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Truman Roscoe Brown

TitleEndowed Chair, Stephen S. Schabel Endowed Chair in Radiology
InstitutionMedical University of South Carolina
DepartmentRadiology and Radiological Science
AddressP.O. Box 323
205
68 President St.
Phone843-876-2462
Fax843-876-2469
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Turan TN, Rumboldt Z, Granholm AC, Columbo L, Welsh CT, Lopes-Virella MF, Spampinato MV, Brown TR. Intracranial atherosclerosis: Correlation between in-vivo 3T high resolution MRI and pathology. Atherosclerosis. 2014 Dec; 237(2):460-3.
      View in: PubMed
    2. Laothamatas J, Sammet CL, Golay X, Van Cauteren M, Lekprasert V, Tangpukdee N, Krudsood S, Leowattana W, Wilairatana P, Swaminathan SV, DeLaPaz RL, Brown TR, Looareesuwan S, Brittenham GM. Transient lesion in the splenium of the corpus callosum in acute uncomplicated falciparum malaria. Am J Trop Med Hyg. 2014 Jun; 90(6):1117-23.
      View in: PubMed
    3. Walz JM, Goldman RI, Carapezza M, Muraskin J, Brown TR, Sajda P. Simultaneous EEG-fMRI reveals temporal evolution of coupling between supramodal cortical attention networks and the brainstem. J Neurosci. 2013 Dec 4; 33(49):19212-22.
      View in: PubMed
    4. Arias-Mendoza F, Payne GS, Zakian K, Stubbs M, O'Connor OA, Mojahed H, Smith MR, Schwarz AJ, Shukla-Dave A, Howe F, Poptani H, Lee SC, Pettengel R, Schuster SJ, Cunningham D, Heerschap A, Glickson JD, Griffiths JR, Koutcher JA, Leach MO, Brown TR. Noninvasive phosphorus magnetic resonance spectroscopic imaging predicts outcome to first-line chemotherapy in newly diagnosed patients with diffuse large B-cell lymphoma. Acad Radiol. 2013 Sep; 20(9):1122-9.
      View in: PubMed
    5. Walz JM, Goldman RI, Carapezza M, Muraskin J, Brown TR, Sajda P. Simultaneous EEG-fMRI reveals a temporal cascade of task-related and default-mode activations during a simple target detection task. Neuroimage. 2014 Nov 15; 102 Pt 1:229-39.
      View in: PubMed
    6. Zou X, Brown TR. Relaxation by amplitude modulation: A rapid T1 measurement method. Magn Reson Med. 2014 Jun; 71(6):2155-65.
      View in: PubMed
    7. Hanlon CA, Canterberry M, Taylor JJ, DeVries W, Li X, Brown TR, George MS. Probing the frontostriatal loops involved in executive and limbic processing via interleaved TMS and functional MRI at two prefrontal locations: a pilot study. PLoS One. 2013; 8(7):e67917.
      View in: PubMed
    8. Tang H, Jensen JH, Sammet CL, Sheth S, Swaminathan SV, Hultman K, Kim D, Wu EX, Brown TR, Brittenham GM. MR characterization of hepatic storage iron in transfusional iron overload. J Magn Reson Imaging. 2014 Feb; 39(2):307-16.
      View in: PubMed
    9. Taylor JJ, Borckardt JJ, Canterberry M, Li X, Hanlon CA, Brown TR, George MS. Naloxone-reversible modulation of pain circuitry by left prefrontal rTMS. Neuropsychopharmacology. 2013 Jun; 38(7):1189-97.
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    10. Muraskin J, Ooi MB, Goldman RI, Krueger S, Thomas WJ, Sajda P, Brown TR. Prospective active marker motion correction improves statistical power in BOLD fMRI. Neuroimage. 2013 Mar; 68:154-61.
      View in: PubMed
    11. Brickman AM, Provenzano FA, Muraskin J, Manly JJ, Blum S, Apa Z, Stern Y, Brown TR, Luchsinger JA, Mayeux R. Regional white matter hyperintensity volume, not hippocampal atrophy, predicts incident Alzheimer disease in the community. Arch Neurol. 2012 Dec; 69(12):1621-7.
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    12. Turan TN, Rumboldt Z, Brown TR. High-resolution MRI of basilar atherosclerosis: three-dimensional acquisition and FLAIR sequences. Brain Behav. 2013 Jan; 3(1):1-3.
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    13. Ooi MB, Muraskin J, Zou X, Thomas WJ, Krueger S, Aksoy M, Bammer R, Brown TR. Combined prospective and retrospective correction to reduce motion-induced image misalignment and geometric distortions in EPI. Magn Reson Med. 2013 Mar 1; 69(3):803-11.
      View in: PubMed
    14. Blum S, Luchsinger JA, Manly JJ, Schupf N, Stern Y, Brown TR, DeCarli C, Small SA, Mayeux R, Brickman AM. Memory after silent stroke: hippocampus and infarcts both matter. Neurology. 2012 Jan 3; 78(1):38-46.
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    15. Taei-Tehrani MR, Van Osch MJ, Brown TR. Pseudo-random arterial modulation (PRAM): a novel arterial spin labeling approach to measure flow and blood transit times. J Magn Reson Imaging. 2012 Jan; 35(1):223-8.
      View in: PubMed
    16. Cheung JS, Au WY, Ha SY, Kim D, Jensen JH, Zhou IY, Cheung MM, Wu Y, Guo H, Khong PL, Brown TR, Brittenham GM, Wu EX. Reduced transverse relaxation rate (RR2) for improved sensitivity in monitoring myocardial iron in thalassemia. J Magn Reson Imaging. 2011 Jun; 33(6):1510-6.
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    17. Debettencourt M, Goldman R, Brown T, Sajda P. Adaptive Thresholding for Improving Sensitivity in Single-Trial Simultaneous EEG/fMRI. Front Psychol. 2011; 2:91.
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    18. Ooi MB, Krueger S, Muraskin J, Thomas WJ, Brown TR. Echo-planar imaging with prospective slice-by-slice motion correction using active markers. Magn Reson Med. 2011 Jul; 66(1):73-81.
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    19. Chen C, Brenner DJ, Brown TR. Identification of urinary biomarkers from X-irradiated mice using NMR spectroscopy. Radiat Res. 2011 May; 175(5):622-30.
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    20. Wu EX, Kim D, Tosti CL, Tang H, Jensen JH, Cheung JS, Feng L, Au WY, Ha SY, Sheth SS, Brown TR, Brittenham GM. Magnetic resonance assessment of iron overload by separate measurement of tissue ferritin and hemosiderin iron. Ann N Y Acad Sci. 2010 Aug; 1202:115-22.
      View in: PubMed
    21. Jensen JH, Tang H, Tosti CL, Swaminathan SV, Nunez A, Hultman K, Szulc KU, Wu EX, Kim D, Sheth S, Brown TR, Brittenham GM. Separate MRI quantification of dispersed (ferritin-like) and aggregated (hemosiderin-like) storage iron. Magn Reson Med. 2010 May; 63(5):1201-9.
      View in: PubMed
    22. Brickman AM, Reitz C, Luchsinger JA, Manly JJ, Schupf N, Muraskin J, DeCarli C, Brown TR, Mayeux R. Long-term blood pressure fluctuation and cerebrovascular disease in an elderly cohort. Arch Neurol. 2010 May; 67(5):564-9.
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    23. Brickman AM, Siedlecki KL, Muraskin J, Manly JJ, Luchsinger JA, Yeung LK, Brown TR, DeCarli C, Stern Y. White matter hyperintensities and cognition: testing the reserve hypothesis. Neurobiol Aging. 2011 Sep; 32(9):1588-98.
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    24. Reitz C, Brickman AM, Brown TR, Manly J, DeCarli C, Small SA, Mayeux R. Linking hippocampal structure and function to memory performance in an aging population. Arch Neurol. 2009 Nov; 66(11):1385-92.
      View in: PubMed
    25. Looareesuwan S, Laothamatas J, Brown TR, Brittenham GM. Cerebral malaria: a new way forward with magnetic resonance imaging (MRI). Am J Trop Med Hyg. 2009 Oct; 81(4):545-7.
      View in: PubMed
    26. Ooi MB, Krueger S, Thomas WJ, Swaminathan SV, Brown TR. Prospective real-time correction for arbitrary head motion using active markers. Magn Reson Med. 2009 Oct; 62(4):943-54.
      View in: PubMed
    27. Asllani I, Habeck C, Borogovac A, Brown TR, Brickman AM, Stern Y. Separating function from structure in perfusion imaging of the aging brain. Hum Brain Mapp. 2009 Sep; 30(9):2927-35.
      View in: PubMed
    28. Wright CB, Moon Y, Paik MC, Brown TR, Rabbani L, Yoshita M, DeCarli C, Sacco R, Elkind MS. Inflammatory biomarkers of vascular risk as correlates of leukoariosis. Stroke. 2009 Nov; 40(11):3466-71.
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    29. Luchsinger JA, Brickman AM, Reitz C, Cho SJ, Schupf N, Manly JJ, Tang MX, Small SA, Mayeux R, DeCarli C, Brown TR. Subclinical cerebrovascular disease in mild cognitive impairment. Neurology. 2009 Aug 11; 73(6):450-6.
      View in: PubMed
    30. Guo H, Au WY, Cheung JS, Kim D, Jensen JH, Khong PL, Chan Q, Chan KC, Tosti C, Tang H, Brown TR, Lam WW, Ha SY, Brittenham GM, Wu EX. Myocardial T2 quantitation in patients with iron overload at 3 Tesla. J Magn Reson Imaging. 2009 Aug; 30(2):394-400.
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    31. Reitz C, Schupf N, Luchsinger JA, Brickman AM, Manly JJ, Andrews H, Tang MX, DeCarli C, Brown TR, Mayeux R. Validity of self-reported stroke in elderly African Americans, Caribbean Hispanics, and Whites. Arch Neurol. 2009 Jul; 66(7):834-40.
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    32. Goldman RI, Wei CY, Philiastides MG, Gerson AD, Friedman D, Brown TR, Sajda P. Single-trial discrimination for integrating simultaneous EEG and fMRI: identifying cortical areas contributing to trial-to-trial variability in the auditory oddball task. Neuroimage. 2009 Aug 1; 47(1):136-47.
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    33. Friedman D, Goldman R, Stern Y, Brown TR. The brain's orienting response: An event-related functional magnetic resonance imaging investigation. Hum Brain Mapp. 2009 Apr; 30(4):1144-54.
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    34. Brickman AM, Zahra A, Muraskin J, Steffener J, Holland CM, Habeck C, Borogovac A, Ramos MA, Brown TR, Asllani I, Stern Y. Reduction in cerebral blood flow in areas appearing as white matter hyperintensities on magnetic resonance imaging. Psychiatry Res. 2009 May 15; 172(2):117-20.
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    35. Dyrholm M, Goldman R, Sajda P, Brown TR. Removal of BCG artifacts using a non-Kirchhoffian overcomplete representation. IEEE Trans Biomed Eng. 2009 Feb; 56(2):200-4.
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    36. Duan Y, Peterson BS, Liu F, Brown TR, Ibrahim TS, Kangarlu A. Computational and experimental optimization of a double-tuned (1)H/(31)P four-ring birdcage head coil for MRS at 3T. J Magn Reson Imaging. 2009 Jan; 29(1):13-22.
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    37. Louis ED, Brickman AM, DeCarli C, Small SA, Marder K, Schupf N, Brown TR. Quantitative brain measurements in community-dwelling elderly persons with mild parkinsonian signs. Arch Neurol. 2008 Dec; 65(12):1649-54.
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    38. Asllani I, Borogovac A, Brown TR. Regression algorithm correcting for partial volume effects in arterial spin labeling MRI. Magn Reson Med. 2008 Dec; 60(6):1362-71.
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    39. Devanand DP, Tabert MH, Cuasay K, Manly JJ, Schupf N, Brickman AM, Andrews H, Brown TR, DeCarli C, Mayeux R. Olfactory identification deficits and MCI in a multi-ethnic elderly community sample. Neurobiol Aging. 2010 Sep; 31(9):1593-600.
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    40. Lee WN, Qian Z, Tosti CL, Brown TR, Metaxas DN, Konofagou EE. Preliminary validation of angle-independent myocardial elastography using MR tagging in a clinical setting. Ultrasound Med Biol. 2008 Dec; 34(12):1980-97.
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    41. Brickman AM, Schupf N, Manly JJ, Luchsinger JA, Andrews H, Tang MX, Reitz C, Small SA, Mayeux R, DeCarli C, Brown TR. Brain morphology in older African Americans, Caribbean Hispanics, and whites from northern Manhattan. Arch Neurol. 2008 Aug; 65(8):1053-61.
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    42. Choi JJ, Wang S, Brown TR, Small SA, Duff KE, Konofagou EE. Noninvasive and transient blood-brain barrier opening in the hippocampus of Alzheimer's double transgenic mice using focused ultrasound. Ultrason Imaging. 2008 Jul; 30(3):189-200.
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    43. Hultman KL, Raffo AJ, Grzenda AL, Harris PE, Brown TR, O'Brien S. Magnetic resonance imaging of major histocompatibility class II expression in the renal medulla using immunotargeted superparamagnetic iron oxide nanoparticles. ACS Nano. 2008 Mar; 2(3):477-84.
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    44. Wright CB, Festa JR, Paik MC, Schmiedigen A, Brown TR, Yoshita M, DeCarli C, Sacco R, Stern Y. White matter hyperintensities and subclinical infarction: associations with psychomotor speed and cognitive flexibility. Stroke. 2008 Mar; 39(3):800-5.
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    45. Sigmund EE, Cho H, Chen P, Byrnes S, Song YQ, Guo XE, Brown TR. Diffusion-based MR methods for bone structure and evolution. Magn Reson Med. 2008 Jan; 59(1):28-39.
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    46. Asllani I, Habeck C, Scarmeas N, Borogovac A, Brown TR, Stern Y. Multivariate and univariate analysis of continuous arterial spin labeling perfusion MRI in Alzheimer's disease. J Cereb Blood Flow Metab. 2008 Apr; 28(4):725-36.
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    47. Asllani I, Borogovac A, Wright C, Sacco R, Brown TR, Zarahn E. An investigation of statistical power for continuous arterial spin labeling imaging at 1.5 T. Neuroimage. 2008 Feb 1; 39(3):1246-56.
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    48. Moreno H, Wu WE, Lee T, Brickman A, Mayeux R, Brown TR, Small SA. Imaging the Abeta-related neurotoxicity of Alzheimer disease. Arch Neurol. 2007 Oct; 64(10):1467-77.
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    49. Choi JJ, Pernot M, Brown TR, Small SA, Konofagou EE. Spatio-temporal analysis of molecular delivery through the blood-brain barrier using focused ultrasound. Phys Med Biol. 2007 Sep 21; 52(18):5509-30.
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    50. Pereira AC, Huddleston DE, Brickman AM, Sosunov AA, Hen R, McKhann GM, Sloan R, Gage FH, Brown TR, Small SA. An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus. Proc Natl Acad Sci U S A. 2007 Mar 27; 104(13):5638-43.
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    51. Tabert MH, Steffener J, Albers MW, Kern DW, Michael M, Tang H, Brown TR, Devanand DP. Validation and optimization of statistical approaches for modeling odorant-induced fMRI signal changes in olfactory-related brain areas. Neuroimage. 2007 Feb 15; 34(4):1375-90.
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    52. Zhao Q, Stoyanova R, Du S, Sajda P, Brown TR. HiRes--a tool for comprehensive assessment and interpretation of metabolomic data. Bioinformatics. 2006 Oct 15; 22(20):2562-4.
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    53. Arias-Mendoza F, Payne GS, Zakian KL, Schwarz AJ, Stubbs M, Stoyanova R, Ballon D, Howe FA, Koutcher JA, Leach MO, Griffiths JR, Heerschap A, Glickson JD, Nelson SJ, Evelhoch JL, Charles HC, Brown TR. In vivo 31P MR spectral patterns and reproducibility in cancer patients studied in a multi-institutional trial. NMR Biomed. 2006 Jun; 19(4):504-12.
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    54. Coon AL, Arias-Mendoza F, Colby GP, Cruz-Lobo J, Mocco J, Mack WJ, Komotar RJ, Brown TR, Connolly ES. Correlation of cerebral metabolites with functional outcome in experimental primate stroke using in vivo 1H-magnetic resonance spectroscopy. AJNR Am J Neuroradiol. 2006 May; 27(5):1053-8.
      View in: PubMed
    55. Wright CB, Paik MC, Brown TR, Stabler SP, Allen RH, Sacco RL, DeCarli C. Total homocysteine is associated with white matter hyperintensity volume: the Northern Manhattan Study. Stroke. 2005 Jun; 36(6):1207-11.
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    56. Sheth S, Tang H, Jensen JH, Altmann K, Prakash A, Printz BF, Hordof AJ, Tosti CL, Azabagic A, Swaminathan S, Brown TR, Olivieri NF, Brittenham GM. Methods for noninvasive measurement of tissue iron in Cooley's anemia. Ann N Y Acad Sci. 2005; 1054:358-72.
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    57. Sajda P, Du S, Brown TR, Stoyanova R, Shungu DC, Mao X, Parra LC. Nonnegative matrix factorization for rapid recovery of constituent spectra in magnetic resonance chemical shift imaging of the brain. IEEE Trans Med Imaging. 2004 Dec; 23(12):1453-65.
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    58. Robinson JN, Cleary-Goldman J, Arias-Mendoza F, Cruz-Lobo J, Tempany C, Mulkern RV, Feinberg BB, Brown TR. Detection of fetal lactate with two-dimensional-localized proton magnetic resonance spectroscopy. Obstet Gynecol. 2004 Nov; 104(5 Pt 2):1208-10.
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    59. Arias-Mendoza F, Zakian K, Schwartz A, Howe FA, Koutcher JA, Leach MO, Griffiths JR, Heerschap A, Glickson JD, Nelson SJ, Evelhoch JL, Charles HC, Brown TR. Methodological standardization for a multi-institutional in vivo trial of localized 31P MR spectroscopy in human cancer research. In vitro and normal volunteer studies. NMR Biomed. 2004 Oct; 17(6):382-91.
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    60. Stoyanova R, Nicholls AW, Nicholson JK, Lindon JC, Brown TR. Automatic alignment of individual peaks in large high-resolution spectral data sets. J Magn Reson. 2004 Oct; 170(2):329-35.
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    61. Stoyanova R, Nicholson JK, Lindon JC, Brown TR. Sample classification based on Bayesian spectral decomposition of metabonomic NMR data sets. Anal Chem. 2004 Jul 1; 76(13):3666-74.
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    62. Arias-Mendoza F, Smith MR, Brown TR. Predicting treatment response in non-Hodgkin's lymphoma from the pretreatment tumor content of phosphoethanolamine plus phosphocholine. Acad Radiol. 2004 Apr; 11(4):368-76.
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    63. Stoyanova R, Querec TD, Brown TR, Patriotis C. Normalization of single-channel DNA array data by principal component analysis. Bioinformatics. 2004 Jul 22; 20(11):1772-84.
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    64. Brown TR, Su B, Brown KA, Schwartz MA, Tobia AM, Kappler F. Modulation of in vivo 3-deoxyglucosone levels. Biochem Soc Trans. 2003 Dec; 31(Pt 6):1433-7.
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    65. Arias-Mendoza F, Brown TR. In vivo measurement of phosphorous markers of disease. Dis Markers. 2003-2004; 19(2-3):49-68.
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    66. Franks SE, Smith MR, Arias-Mendoza F, Shaller C, Padavic-Shaller K, Kappler F, Zhang Y, Negendank WG, Brown TR. Phosphomonoester concentrations differ between chronic lymphocytic leukemia cells and normal human lymphocytes. Leuk Res. 2002 Oct; 26(10):919-26.
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    67. Shukla-Dave A, Poptani H, Loevner LA, Mancuso A, Serrai H, Rosenthal DI, Kilger AM, Nelson DS, Zakian KL, Arias-Mendoza F, Rijpkema M, Koutcher JA, Brown TR, Heerschap A, Glickson JD. Prediction of treatment response of head and neck cancers with P-31 MR spectroscopy from pretreatment relative phosphomonoester levels. Acad Radiol. 2002 Jun; 9(6):688-94.
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