Keywords
Last Name
Institution

Mitzi Nagarkatti

TitleDEPARTMENT CHAIR/PROF
InstitutionUniversity of South Carolina School of Medicine
DepartmentMDC PATH-MICRO
AddressMEDICAL V.A. #1
Columbia, South Carolina 29209
Phone(803)216-3404
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Busbee PB, Menzel L, Alrafas HR, Dopkins N, Becker W, Miranda K, Tang C, Chatterjee S, Singh U, Nagarkatti M, Nagarkatti PS. Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22-dependent manner. JCI Insight. 2020 01 16; 5(1). PMID: 31941837.
      View in: PubMed
    2. Rahman MA, Jui MS, Bam M, Cha Y, Luat E, Alabresm A, Nagarkatti M, Decho AW, Tang C. Facial Amphiphilicity-Induced Polymer Nanostructures for Antimicrobial Applications. ACS Appl Mater Interfaces. 2020 Jan 15. PMID: 31939652.
      View in: PubMed
    3. Alrafas HR, Busbee PB, Nagarkatti M, Nagarkatti PS. Resveratrol Downregulates miR-31 to Promote T Regulatory Cells during Prevention of TNBS-Induced Colitis. Mol Nutr Food Res. 2020 Jan; 64(1):e1900633. PMID: 31730734.
      View in: PubMed
    4. Yang X, Bam M, Nagarkatti PS, Nagarkatti M. Cannabidiol Regulates Gene Expression in Encephalitogenic T cells Using Histone Methylation and noncoding RNA during Experimental Autoimmune Encephalomyelitis. Sci Rep. 2019 Oct 31; 9(1):15780. PMID: 31673072.
      View in: PubMed
    5. Sarkar S, Alhasson F, Kimono D, Albadrani M, Seth RK, Xiao S, Porter DE, Scott GI, Brooks B, Nagarkatti M, Nagarkatti P, Chatterjee S. Microcystin exposure worsens nonalcoholic fatty liver disease associated ectopic glomerular toxicity via NOX-2-MIR21 axis. Environ Toxicol Pharmacol. 2020 Jan; 73:103281. PMID: 31706246.
      View in: PubMed
    6. Al-Ghezi ZZ, Singh N, Mehrpouya-Bahrami P, Busbee PB, Nagarkatti M, Nagarkatti PS. AhR Activation by TCDD (2,3,7,8-Tetrachlorodibenzo-p-dioxin) Attenuates Pertussis Toxin-Induced Inflammatory Responses by Differential Regulation of Tregs and Th17 Cells Through Specific Targeting by microRNA. Front Microbiol. 2019; 10:2349. PMID: 31681214.
      View in: PubMed
    7. Kimono D, Sarkar S, Albadrani M, Seth R, Bose D, Mondal A, Li Y, Kar AN, Nagarkatti M, Nagarkatti P, Sullivan K, Janulewicz P, Lasley S, Horner R, Klimas N, Chatterjee S. Dysbiosis-Associated Enteric Glial Cell Immune-Activation and Redox Imbalance Modulate Tight Junction Protein Expression in Gulf War Illness Pathology. Front Physiol. 2019; 10:1229. PMID: 31680990.
      View in: PubMed
    8. Neamah WH, Singh NP, Alghetaa H, Abdulla OA, Chatterjee S, Busbee PB, Nagarkatti M, Nagarkatti P. AhR Activation Leads to Massive Mobilization of Myeloid-Derived Suppressor Cells with Immunosuppressive Activity through Regulation of CXCR2 and MicroRNA miR-150-5p and miR-543-3p That Target Anti-Inflammatory Genes. J Immunol. 2019 Oct 01; 203(7):1830-1844. PMID: 31492743.
      View in: PubMed
    9. Velázquez KT, Enos RT, Bader JE, Sougiannis AT, Carson MS, Chatzistamou I, Carson JA, Nagarkatti PS, Nagarkatti M, Murphy EA. Prolonged high-fat-diet feeding promotes non-alcoholic fatty liver disease and alters gut microbiota in mice. World J Hepatol. 2019 Aug 27; 11(8):619-637. PMID: 31528245.
      View in: PubMed
    10. Al-Ghezi ZZ, Miranda K, Nagarkatti M, Nagarkatti PS. Combination of Cannabinoids, ?9- Tetrahydrocannabinol and Cannabidiol, Ameliorates Experimental Multiple Sclerosis by Suppressing Neuroinflammation Through Regulation of miRNA-Mediated Signaling Pathways. Front Immunol. 2019; 10:1921. PMID: 31497013.
      View in: PubMed
    11. Wang Y, Liu M, Johnson SB, Yuan G, Arriba AK, Zubizarreta ME, Chatterjee S, Nagarkatti M, Nagarkatti P, Xiao S. Doxorubicin obliterates mouse ovarian reserve through both primordial follicle atresia and overactivation. Toxicol Appl Pharmacol. 2019 Oct 15; 381:114714. PMID: 31437492.
      View in: PubMed
    12. Albadrani M, Seth RK, Sarkar S, Kimono D, Mondal A, Bose D, Porter DE, Scott GI, Brooks B, Raychoudhury S, Nagarkatti M, Nagarkatti P, Jule Y, Diehl AM, Chatterjee S. Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21. Am J Physiol Gastrointest Liver Physiol. 2019 Oct 01; 317(4):G408-G428. PMID: 31393787.
      View in: PubMed
    13. Al-Ghezi ZZ, Busbee PB, Alghetaa H, Nagarkatti PS, Nagarkatti M. Combination of cannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), mitigates experimental autoimmune encephalomyelitis (EAE) by altering the gut microbiome. Brain Behav Immun. 2019 Nov; 82:25-35. PMID: 31356922.
      View in: PubMed
    14. Oza M, Becker W, Gummadidala PM, Dias T, Omebeyinje MH, Chen L, Mitra C, Jesmin R, Chakraborty P, Sajish M, Hofseth LJ, Banerjee K, Wang Q, Moeller PDR, Nagarkatti M, Nagarkatti P, Chanda A. Acute and short-term administrations of delta-9-tetrahydrocannabinol modulate major gut metabolomic regulatory pathways in C57BL/6 mice. Sci Rep. 2019 Jul 19; 9(1):10520. PMID: 31324830.
      View in: PubMed
    15. Sarkar S, Kimono D, Albadrani M, Seth RK, Busbee P, Alghetaa H, Porter DE, Scott GI, Brooks B, Nagarkatti M, Nagarkatti P, Chatterjee S. Environmental microcystin targets the microbiome and increases the risk of intestinal inflammatory pathology via NOX2 in underlying murine model of Nonalcoholic Fatty Liver Disease. Sci Rep. 2019 Jun 19; 9(1):8742. PMID: 31217465.
      View in: PubMed
    16. Chitrala KN, Nagarkatti M, Nagarkatti P, Yeguvapalli S. Analysis of the TP53 Deleterious Single Nucleotide Polymorphisms Impact on Estrogen Receptor Alpha-p53 Interaction: A Machine Learning Approach. Int J Mol Sci. 2019 Jun 18; 20(12). PMID: 31216622.
      View in: PubMed
    17. Miranda K, Mehrpouya-Bahrami P, Nagarkatti PS, Nagarkatti M. Cannabinoid Receptor 1 Blockade Attenuates Obesity and Adipose Tissue Type 1 Inflammation Through miR-30e-5p Regulation of Delta-Like-4 in Macrophages and Consequently Downregulation of Th1 Cells. Front Immunol. 2019; 10:1049. PMID: 31134094.
      View in: PubMed
    18. Gandy KAO, Zhang J, Nagarkatti P, Nagarkatti M. The role of gut microbiota in shaping the relapse-remitting and chronic-progressive forms of multiple sclerosis in mouse models. Sci Rep. 2019 May 06; 9(1):6923. PMID: 31061496.
      View in: PubMed
    19. Chitrala KN, Yang X, Busbee B, Singh NP, Bonati L, Xing Y, Nagarkatti P, Nagarkatti M. Computational prediction and in vitro validation of VEGFR1 as a novel protein target for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Sci Rep. 2019 May 02; 9(1):6810. PMID: 31048752.
      View in: PubMed
    20. Shidal C, Singh NP, Nagarkatti P, Nagarkatti M. MicroRNA-92 Expression in CD133+ Melanoma Stem Cells Regulates Immunosuppression in the Tumor Microenvironment via Integrin-Dependent Activation of TGFß. Cancer Res. 2019 Jul 15; 79(14):3622-3635. PMID: 31015227.
      View in: PubMed
    21. Gandy KAO, Zhang J, Nagarkatti P, Nagarkatti M. Resveratrol (3, 5, 4'-Trihydroxy-trans-Stilbene) Attenuates a Mouse Model of Multiple Sclerosis by Altering the miR-124/Sphingosine Kinase 1 Axis in Encephalitogenic T Cells in the Brain. J Neuroimmune Pharmacol. 2019 Sep; 14(3):462-477. PMID: 30941623.
      View in: PubMed
    22. Mehrpouya-Bahrami P, Miranda K, Singh NP, Zumbrun EE, Nagarkatti M, Nagarkatti PS. Role of microRNA in CB1 antagonist-mediated regulation of adipose tissue macrophage polarization and chemotaxis during diet-induced obesity. J Biol Chem. 2019 05 10; 294(19):7669-7681. PMID: 30910812.
      View in: PubMed
    23. Alrafas HR, Busbee PB, Nagarkatti M, Nagarkatti PS. Resveratrol modulates the gut microbiota to prevent murine colitis development through induction of Tregs and suppression of Th17 cells. J Leukoc Biol. 2019 Aug; 106(2):467-480. PMID: 30897248.
      View in: PubMed
    24. Sougiannis AT, VanderVeen BN, Enos RT, Velazquez KT, Bader JE, Carson M, Chatzistamou I, Walla M, Pena MM, Kubinak JL, Nagarkatti M, Carson JA, Murphy EA. Impact of 5 fluorouracil chemotherapy on gut inflammation, functional parameters, and gut microbiota. Brain Behav Immun. 2019 08; 80:44-55. PMID: 30807838.
      View in: PubMed
    25. Alharris E, Singh NP, Nagarkatti PS, Nagarkatti M. Role of miRNA in the regulation of cannabidiol-mediated apoptosis in neuroblastoma cells. Oncotarget. 2019 Jan 01; 10(1):45-59. PMID: 30713602.
      View in: PubMed
    26. Alharris E, Alghetaa H, Seth R, Chatterjee S, Singh NP, Nagarkatti M, Nagarkatti P. Resveratrol Attenuates Allergic Asthma and Associated Inflammation in the Lungs Through Regulation of miRNA-34a That Targets FoxP3 in Mice. Front Immunol. 2018; 9:2992. PMID: 30619345.
      View in: PubMed
    27. Kadhim S, Singh NP, Zumbrun EE, Cui T, Chatterjee S, Hofseth L, Abood A, Nagarkatti P, Nagarkatti M. Resveratrol-Mediated Attenuation of Staphylococcus aureus Enterotoxin B-Induced Acute Liver Injury Is Associated With Regulation of microRNA and Induction of Myeloid-Derived Suppressor Cells. Front Microbiol. 2018; 9:2910. PMID: 30619104.
      View in: PubMed
    28. Rahman MA, Bam M, Luat E, Jui MS, Ganewatta MS, Shokfai T, Nagarkatti M, Decho AW, Tang C. Macromolecular-clustered facial amphiphilic antimicrobials. Nat Commun. 2018 12 07; 9(1):5231. PMID: 30531920.
      View in: PubMed
    29. Chitrala KN, Yang X, Nagarkatti P, Nagarkatti M. Comparative analysis of interactions between aryl hydrocarbon receptor ligand binding domain with its ligands: a computational study. BMC Struct Biol. 2018 12 06; 18(1):15. PMID: 30522477.
      View in: PubMed
    30. Yang P, Pageni P, Rahman MA, Bam M, Zhu T, Chen YP, Nagarkatti M, Decho AW, Tang C. Gold Nanoparticles with Antibiotic-Metallopolymers toward Broad-Spectrum Antibacterial Effects. Adv Healthc Mater. 2019 03; 8(6):e1800854. PMID: 30480381.
      View in: PubMed
    31. Cranford TL, Velázquez KT, Enos RT, Sougiannis AT, Bader JE, Carson MS, Bellone RR, Chatzistamou I, Nagarkatti M, Murphy EA. Effects of high fat diet-induced obesity on mammary tumorigenesis in the PyMT/MMTV murine model. Cancer Biol Ther. 2019; 20(4):487-496. PMID: 30388923.
      View in: PubMed
    32. Guo G, Zhou J, Yang X, Feng J, Shao Y, Jia T, Huang Q, Li Y, Zhong Y, Nagarkatti PS, Nagarkatti M. Role of MicroRNAs Induced by Chinese Herbal Medicines Against Hepatocellular Carcinoma: A Brief Review. Integr Cancer Ther. 2018 12; 17(4):1059-1067. PMID: 30343602.
      View in: PubMed
    33. Dattaroy D, Seth RK, Sarkar S, Kimono D, Albadrani M, Chandrashekaran V, Hasson FA, Singh UP, Fan D, Nagarkatti M, Nagarkatti P, Diehl AM, Chatterjee S. Sparstolonin B (SsnB) attenuates liver fibrosis via a parallel conjugate pathway involving P53-P21 axis, TGF-beta signaling and focal adhesion that is TLR4 dependent. Eur J Pharmacol. 2018 Dec 15; 841:33-48. PMID: 30194936.
      View in: PubMed
    34. Singh NP, Miranda K, Singh UP, Nagarkatti P, Nagarkatti M. Diethylstilbestrol (DES) induces autophagy in thymocytes by regulating Beclin-1 expression through epigenetic modulation. Toxicology. 2018 12 01; 410:49-58. PMID: 30153466.
      View in: PubMed
    35. Elliott DM, Singh N, Nagarkatti M, Nagarkatti PS. Cannabidiol Attenuates Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Through Induction of Myeloid-Derived Suppressor Cells. Front Immunol. 2018; 9:1782. PMID: 30123217.
      View in: PubMed
    36. Abron JD, Singh NP, Price RL, Nagarkatti M, Nagarkatti PS, Singh UP. Genistein induces macrophage polarization and systemic cytokine to ameliorate experimental colitis. PLoS One. 2018; 13(7):e0199631. PMID: 30024891.
      View in: PubMed
    37. Miranda K, Yang X, Bam M, Murphy EA, Nagarkatti PS, Nagarkatti M. MicroRNA-30 modulates metabolic inflammation by regulating Notch signaling in adipose tissue macrophages. Int J Obes (Lond). 2018 06; 42(6):1140-1150. PMID: 29899524.
      View in: PubMed
    38. Seth RK, Kimono D, Alhasson F, Sarkar S, Albadrani M, Lasley SK, Horner R, Janulewicz P, Nagarkatti M, Nagarkatti P, Sullivan K, Chatterjee S. Increased butyrate priming in the gut stalls microbiome associated-gastrointestinal inflammation and hepatic metabolic reprogramming in a mouse model of Gulf War Illness. Toxicol Appl Pharmacol. 2018 07 01; 350:64-77. PMID: 29751049.
      View in: PubMed
    39. Pageni P, Yang P, Bam M, Zhu T, Chen YP, Decho AW, Nagarkatti M, Tang C. Recyclable magnetic nanoparticles grafted with antimicrobial metallopolymer-antibiotic bioconjugates. Biomaterials. 2018 09; 178:363-372. PMID: 29759729.
      View in: PubMed
    40. Abron JD, Singh NP, Mishra MK, Price RL, Nagarkatti M, Nagarkatti PS, Singh UP. An endogenous aryl hydrocarbon receptor ligand, ITE, induces regulatory T cells and ameliorates experimental colitis. Am J Physiol Gastrointest Liver Physiol. 2018 08 01; 315(2):G220-G230. PMID: 29672155.
      View in: PubMed
    41. Becker W, Nagarkatti M, Nagarkatti PS. miR-466a Targeting of TGF-ß2 Contributes to FoxP3+ Regulatory T Cell Differentiation in a Murine Model of Allogeneic Transplantation. Front Immunol. 2018; 9:688. PMID: 29686677.
      View in: PubMed
    42. Alhasson F, Seth RK, Sarkar S, Kimono DA, Albadrani MS, Dattaroy D, Chandrashekaran V, Scott GI, Raychoudhury S, Nagarkatti M, Nagarkatti P, Diehl AM, Chatterjee S. High circulatory leptin mediated NOX-2-peroxynitrite-miR21 axis activate mesangial cells and promotes renal inflammatory pathology in nonalcoholic fatty liver disease. Redox Biol. 2018 07; 17:1-15. PMID: 29660503.
      View in: PubMed
    43. Abron JD, Singh NP, Murphy AE, Mishra MK, Price RL, Nagarkatti M, Nagarkatti PS, Singh UP. Differential role of CXCR3 in inflammation and colorectal cancer. Oncotarget. 2018 Apr 03; 9(25):17928-17936. PMID: 29707158.
      View in: PubMed
    44. Zhang T, Zhou J, Man GCW, Leung KT, Liang B, Xiao B, Ma X, Huang S, Huang H, Hegde VL, Zhong Y, Li Y, Kong GWS, Yiu AKW, Kwong J, Ng PC, Lessey BA, Nagarkatti PS, Nagarkatti M, Wang CC. MDSCs drive the process of endometriosis by enhancing angiogenesis and are a new potential therapeutic target. Eur J Immunol. 2018 06; 48(6):1059-1073. PMID: 29460338.
      View in: PubMed
    45. Alghetaa H, Mohammed A, Sultan M, Busbee P, Murphy A, Chatterjee S, Nagarkatti M, Nagarkatti P. Resveratrol protects mice against SEB-induced acute lung injury and mortality by miR-193a modulation that targets TGF-ß signalling. J Cell Mol Med. 2018 05; 22(5):2644-2655. PMID: 29512867.
      View in: PubMed
    46. Dopkins N, Nagarkatti PS, Nagarkatti M. The role of gut microbiome and associated metabolome in the regulation of neuroinflammation in multiple sclerosis and its implications in attenuating chronic inflammation in other inflammatory and autoimmune disorders. Immunology. 2018 06; 154(2):178-185. PMID: 29392733.
      View in: PubMed
    47. Dubey S, Yoon H, Cohen MS, Nagarkatti P, Nagarkatti M, Karan D. Withaferin A Associated Differential Regulation of Inflammatory Cytokines. Front Immunol. 2018; 9:195. PMID: 29479354.
      View in: PubMed
    48. Pageni P, Yang P, Chen YP, Huang Y, Bam M, Zhu T, Nagarkatti M, Benicewicz BC, Decho AW, Tang C. Charged Metallopolymer-Grafted Silica Nanoparticles for Antimicrobial Applications. Biomacromolecules. 2018 02 12; 19(2):417-425. PMID: 29384661.
      View in: PubMed
    49. Nagarkatti M, Rieder SA, Nagarkatti PS. Evaluation of Cell Proliferation and Apoptosis in Immunotoxicity Testing. Methods Mol Biol. 2018; 1803:209-230. PMID: 29882142.
      View in: PubMed
    50. Mehrpouya-Bahrami P, Chitrala KN, Ganewatta MS, Tang C, Murphy EA, Enos RT, Velazquez KT, McCellan J, Nagarkatti M, Nagarkatti P. Blockade of CB1 cannabinoid receptor alters gut microbiota and attenuates inflammation and diet-induced obesity. Sci Rep. 2017 11 15; 7(1):15645. PMID: 29142285.
      View in: PubMed
    51. Bader JE, Enos RT, Velázquez KT, Carson MS, Nagarkatti M, Nagarkatti PS, Chatzistamou I, Davis JM, Carson JA, Robinson CM, Murphy EA. Macrophage depletion using clodronate liposomes decreases tumorigenesis and alters gut microbiota in the AOM/DSS mouse model of colon cancer. Am J Physiol Gastrointest Liver Physiol. 2018 01 01; 314(1):G22-G31. PMID: 29025731.
      View in: PubMed
    52. Yang P, Bam M, Pageni P, Zhu T, Chen YP, Nagarkatti M, Decho AW, Tang C. Trio Act of Boronolectin with Antibiotic-Metal Complexed Macromolecules toward Broad-Spectrum Antimicrobial Efficacy. ACS Infect Dis. 2017 11 10; 3(11):845-853. PMID: 28976179.
      View in: PubMed
    53. Nimpong JA, Gebregziabher W, Singh UP, Nagarkatti P, Nagarkatti M, Hodge J, Liu C, Fan D, Ai W. Deficiency of KLF4 compromises the lung function in an acute mouse model of allergic asthma. Biochem Biophys Res Commun. 2017 11 04; 493(1):598-603. PMID: 28867182.
      View in: PubMed
    54. Bam M, Yang X, Zumbrun EE, Ginsberg JP, Leyden Q, Zhang J, Nagarkatti PS, Nagarkatti M. Decreased AGO2 and DCR1 in PBMCs from War Veterans with PTSD leads to diminished miRNA resulting in elevated inflammation. Transl Psychiatry. 2017 08 29; 7(8):e1222. PMID: 28850112.
      View in: PubMed
    55. Chitrala KN, Guan H, Singh NP, Busbee B, Gandy A, Mehrpouya-Bahrami P, Ganewatta MS, Tang C, Chatterjee S, Nagarkatti P, Nagarkatti M. CD44 deletion leading to attenuation of experimental autoimmune encephalomyelitis results from alterations in gut microbiome in mice. Eur J Immunol. 2017 07; 47(7):1188-1199. PMID: 28543188.
      View in: PubMed
    56. Sagar D, Singh NP, Ginwala R, Huang X, Philip R, Nagarkatti M, Nagarkatti P, Neumann K, Ruland J, Andrews AM, Ramirez SH, Khan ZK, Jain P. Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity. Sci Rep. 2017 06 02; 7(1):2707. PMID: 28578388.
      View in: PubMed
    57. Alhasson F, Das S, Seth R, Dattaroy D, Chandrashekaran V, Ryan CN, Chan LS, Testerman T, Burch J, Hofseth LJ, Horner R, Nagarkatti M, Nagarkatti P, Lasley SM, Chatterjee S. Altered gut microbiome in a mouse model of Gulf War Illness causes neuroinflammation and intestinal injury via leaky gut and TLR4 activation. PLoS One. 2017; 12(3):e0172914. PMID: 28328972.
      View in: PubMed
    58. Bam M, Yang X, Sen S, Zumbrun EE, Dennis L, Zhang J, Nagarkatti PS, Nagarkatti M. Characterization of Dysregulated miRNA in Peripheral Blood Mononuclear Cells from Ischemic Stroke Patients. Mol Neurobiol. 2018 02; 55(2):1419-1429. PMID: 28168424.
      View in: PubMed
    59. Cranford TL, Velázquez KT, Enos RT, Bader JE, Carson MS, Chatzistamou I, Nagarkatti M, Murphy EA. Loss of monocyte chemoattractant protein-1 expression delays mammary tumorigenesis and reduces localized inflammation in the C3(1)/SV40Tag triple negative breast cancer model. Cancer Biol Ther. 2017 02; 18(2):85-93. PMID: 28075192.
      View in: PubMed
    60. Chumanevich AA, Chaparala A, Witalison EE, Tashkandi H, Hofseth AB, Lane C, Pena E, Liu P, Pittman DL, Nagarkatti P, Nagarkatti M, Hofseth LJ, Chumanevich AA. Looking for the best anti-colitis medicine: A comparative analysis of current and prospective compounds. Oncotarget. 2017 Jan 03; 8(1):228-237. PMID: 27974688.
      View in: PubMed
    61. Chitrala KN, Nagarkatti P, Nagarkatti M. Prediction of Possible Biomarkers and Novel Pathways Conferring Risk to Post-Traumatic Stress Disorder. PLoS One. 2016; 11(12):e0168404. PMID: 27997584.
      View in: PubMed
    62. Enos RT, Velázquez KT, Carson MS, McClellan JL, Nagarkatti P, Nagarkatti M, Davis JM, Murphy EA. A Low Dose of Dietary Quercetin Fails to Protect against the Development of an Obese Phenotype in Mice. PLoS One. 2016; 11(12):e0167979. PMID: 27959936.
      View in: PubMed
    63. Seth RK, Das S, Dattaroy D, Chandrashekaran V, Alhasson F, Michelotti G, Nagarkatti M, Nagarkatti P, Diehl AM, Bell PD, Liedtke W, Chatterjee S. TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity. Free Radic Biol Med. 2017 01; 102:260-273. PMID: 27913210.
      View in: PubMed
    64. Velázquez KT, Enos RT, Carson MS, Cranford TL, Bader JE, Chatzistamou I, Singh UP, Nagarkatti PS, Nagarkatti M, Davis JM, Carson JA, Murphy EA. Weight loss following diet-induced obesity does not alter colon tumorigenesis in the AOM mouse model. Am J Physiol Gastrointest Liver Physiol. 2016 10 01; 311(4):G699-G712. PMID: 27609769.
      View in: PubMed
    65. Finnell JE, Lombard CM, Melson MN, Singh NP, Nagarkatti M, Nagarkatti P, Fadel JR, Wood CS, Wood SK. The protective effects of resveratrol on social stress-induced cytokine release and depressive-like behavior. Brain Behav Immun. 2017 Jan; 59:147-157. PMID: 27592314.
      View in: PubMed
    66. Chumanevich AA, Witalison EE, Chaparala A, Chumanevich A, Nagarkatti P, Nagarkatti M, Hofseth LJ. Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties. Oncotarget. 2016 Aug 16; 7(33):52928-52939. PMID: 27447967.
      View in: PubMed
    67. Bam M, Yang X, Zumbrun EE, Zhong Y, Zhou J, Ginsberg JP, Leyden Q, Zhang J, Nagarkatti PS, Nagarkatti M. Dysregulated immune system networks in war veterans with PTSD is an outcome of altered miRNA expression and DNA methylation. Sci Rep. 2016 08 11; 6:31209. PMID: 27510991.
      View in: PubMed
    68. Shamran H, Singh NP, Zumbrun EE, Murphy A, Taub DD, Mishra MK, Price RL, Chatterjee S, Nagarkatti M, Nagarkatti PS, Singh UP. Fatty acid amide hydrolase (FAAH) blockade ameliorates experimental colitis by altering microRNA expression and suppressing inflammation. Brain Behav Immun. 2017 Jan; 59:10-20. PMID: 27327245.
      View in: PubMed
    69. Yang X, Bam M, Nagarkatti PS, Nagarkatti M. RNA-seq Analysis of d9-Tetrahydrocannabinol-treated T Cells Reveals Altered Gene Expression Profiles That Regulate Immune Response and Cell Proliferation. J Biol Chem. 2016 07 22; 291(30):15460-72. PMID: 27268054.
      View in: PubMed
    70. Sido JM, Nagarkatti PS, Nagarkatti M. Production of endocannabinoids by activated T cells and B cells modulates inflammation associated with delayed-type hypersensitivity. Eur J Immunol. 2016 06; 46(6):1472-9. PMID: 27064137.
      View in: PubMed
    71. Huang Q, Xiao B, Ma X, Qu M, Li Y, Nagarkatti P, Nagarkatti M, Zhou J. MicroRNAs associated with the pathogenesis of multiple sclerosis. J Neuroimmunol. 2016 06 15; 295-296:148-61. PMID: 27235360.
      View in: PubMed
    72. Elliott DM, Nagarkatti M, Nagarkatti PS. 3,39-Diindolylmethane Ameliorates Staphylococcal Enterotoxin B–Induced Acute Lung Injury through Alterations in the Expression of MicroRNA that Target Apoptosis and Cell-Cycle Arrest in Activated T Cells. J Pharmacol Exp Ther. 2016 Apr; 357(1):177-87. PMID: 26818958.
      View in: PubMed
    73. Sido JM, Jackson AR, Nagarkatti PS, Nagarkatti M. Marijuana-derived ?-9-tetrahydrocannabinol suppresses Th1/Th17 cell-mediated delayed-type hypersensitivity through microRNA regulation. J Mol Med (Berl). 2016 09; 94(9):1039-51. PMID: 27038180.
      View in: PubMed
    74. Enos RT, Velázquez KT, McClellan JL, Cranford TL, Nagarkatti M, Nagarkatti PS, Davis JM, Murphy EA. High-fat diets rich in saturated fat protect against azoxymethane/dextran sulfate sodium-induced colon cancer. Am J Physiol Gastrointest Liver Physiol. 2016 06 01; 310(11):G906-19. PMID: 27033117.
      View in: PubMed
    75. Guan H, Singh UP, Rao R, Mrelashvili D, Sen S, Hao H, Zumbrun EE, Singh NP, Nagarkatti PS, Nagarkatti M. Inverse correlation of expression of microRNA-140-5p with progression of multiple sclerosis and differentiation of encephalitogenic T helper type 1 cells. Immunology. 2016 Apr; 147(4):488-98. PMID: 26780721.
      View in: PubMed
    76. Velázquez KT, Enos RT, McClellan JL, Cranford TL, Chatzistamou I, Singh UP, Nagarkatti M, Nagarkatti PS, Fan D, Murphy EA. MicroRNA-155 deletion promotes tumorigenesis in the azoxymethane-dextran sulfate sodium model of colon cancer. Am J Physiol Gastrointest Liver Physiol. 2016 Mar 15; 310(6):G347-58. PMID: 26744471.
      View in: PubMed
    77. Dattaroy D, Seth RK, Das S, Alhasson F, Chandrashekaran V, Michelotti G, Fan D, Nagarkatti M, Nagarkatti P, Diehl AM, Chatterjee S. Sparstolonin B attenuates early liver inflammation in experimental NASH by modulating TLR4 trafficking in lipid rafts via NADPH oxidase activation. Am J Physiol Gastrointest Liver Physiol. 2016 04 01; 310(7):G510-25. PMID: 26718771.
      View in: PubMed
    78. Singh NP, Singh UP, Rouse M, Zhang J, Chatterjee S, Nagarkatti PS, Nagarkatti M. Dietary Indoles Suppress Delayed-Type Hypersensitivity by Inducing a Switch from Proinflammatory Th17 Cells to Anti-Inflammatory Regulatory T Cells through Regulation of MicroRNA. J Immunol. 2016 Feb 01; 196(3):1108-22. PMID: 26712945.
      View in: PubMed
    79. Monsanto SP, Edwards AK, Zhou J, Nagarkatti P, Nagarkatti M, Young SL, Lessey BA, Tayade C. Surgical removal of endometriotic lesions alters local and systemic proinflammatory cytokines in endometriosis patients. Fertil Steril. 2016 Apr; 105(4):968-977.e5. PMID: 26698677.
      View in: PubMed
    80. Cranford TL, Enos RT, Velázquez KT, McClellan JL, Davis JM, Singh UP, Nagarkatti M, Nagarkatti PS, Robinson CM, Murphy EA. Role of MCP-1 on inflammatory processes and metabolic dysfunction following high-fat feedings in the FVB/N strain. Int J Obes (Lond). 2016 05; 40(5):844-51. PMID: 26620890.
      View in: PubMed
    81. Bam M, Yang X, Zhou J, Ginsberg JP, Leyden Q, Nagarkatti PS, Nagarkatti M. Evidence for Epigenetic Regulation of Pro-Inflammatory Cytokines, Interleukin-12 and Interferon Gamma, in Peripheral Blood Mononuclear Cells from PTSD Patients. J Neuroimmune Pharmacol. 2016 Mar; 11(1):168-181. PMID: 26589234.
      View in: PubMed
    82. Qin Q, Qu C, Niu T, Zang H, Qi L, Lyu L, Wang X, Nagarkatti M, Nagarkatti P, Janicki JS, Wang XL, Cui T. Nrf2-Mediated Cardiac Maladaptive Remodeling and Dysfunction in a Setting of Autophagy Insufficiency. Hypertension. 2016 Jan; 67(1):107-17. PMID: 26573705.
      View in: PubMed
    83. Singh UP, Singh NP, Murphy EA, Price RL, Fayad R, Nagarkatti M, Nagarkatti PS. Chemokine and cytokine levels in inflammatory bowel disease patients. Cytokine. 2016 Jan; 77:44-9. PMID: 26520877.
      View in: PubMed
    84. Chandrashekaran V, Das S, Seth RK, Dattaroy D, Alhasson F, Michelotti G, Nagarkatti M, Nagarkatti P, Diehl AM, Chatterjee S. Purinergic receptor X7 mediates leptin induced GLUT4 function in stellate cells in nonalcoholic steatohepatitis. Biochim Biophys Acta. 2016 01; 1862(1):32-45. PMID: 26474534.
      View in: PubMed
    85. Lyu L, Wang H, Li B, Qin Q, Qi L, Nagarkatti M, Nagarkatti P, Janicki JS, Wang XL, Cui T. A critical role of cardiac fibroblast-derived exosomes in activating renin angiotensin system in cardiomyocytes. J Mol Cell Cardiol. 2015 Dec; 89(Pt B):268-79. PMID: 26497614.
      View in: PubMed
    86. Leach DF, Nagarkatti M, Nagarkatti P, Cui T. Functional states of resident vascular stem cells and vascular remodeling. Front Biol (Beijing). 2015 Oct 01; 10(5):387-397. PMID: 26913049.
      View in: PubMed
    87. Shamran HA, Ghazi HF, Al-Salman A, Al-Juboory AA, Taub DD, Price RL, Nagarkatti M, Nagarkatti PS, Singh UP. Single Nucleotide Polymorphisms in IL-10, IL-12p40, and IL-13 Genes and Susceptibility to Glioma. Int J Med Sci. 2015; 12(10):790-6. PMID: 26516307.
      View in: PubMed
    88. Ganewatta MS, Miller KP, Singleton SP, Mehrpouya-Bahrami P, Chen YP, Yan Y, Nagarkatti M, Nagarkatti P, Decho AW, Tang C. Antibacterial and Biofilm-Disrupting Coatings from Resin Acid-Derived Materials. Biomacromolecules. 2015 Oct 12; 16(10):3336-44. PMID: 26324023.
      View in: PubMed
    89. Ginwala R, McTish E, Raman C, Singh N, Nagarkatti M, Nagarkatti P, Sagar D, Jain P, Khan ZK. Apigenin, a Natural Flavonoid, Attenuates EAE Severity Through the Modulation of Dendritic Cell and Other Immune Cell Functions. J Neuroimmune Pharmacol. 2016 Mar; 11(1):36-47. PMID: 26040501.
      View in: PubMed
    90. Sido JM, Nagarkatti PS, Nagarkatti M. ??-Tetrahydrocannabinol attenuates allogeneic host-versus-graft response and delays skin graft rejection through activation of cannabinoid receptor 1 and induction of myeloid-derived suppressor cells. J Leukoc Biol. 2015 Sep; 98(3):435-47. PMID: 26034207.
      View in: PubMed
    91. Das S, Alhasson F, Dattaroy D, Pourhoseini S, Seth RK, Nagarkatti M, Nagarkatti PS, Michelotti GA, Diehl AM, Kalyanaraman B, Chatterjee S. NADPH Oxidase-Derived Peroxynitrite Drives Inflammation in Mice and Human Nonalcoholic Steatohepatitis via TLR4-Lipid Raft Recruitment. Am J Pathol. 2015 Jul; 185(7):1944-57. PMID: 25989356.
      View in: PubMed
    92. Hegde VL, Singh UP, Nagarkatti PS, Nagarkatti M. Critical Role of Mast Cells and Peroxisome Proliferator-Activated Receptor ? in the Induction of Myeloid-Derived Suppressor Cells by Marijuana Cannabidiol In Vivo. J Immunol. 2015 Jun 01; 194(11):5211-22. PMID: 25917103.
      View in: PubMed
    93. Qu C, Li B, Lai Y, Li H, Windust A, Hofseth LJ, Nagarkatti M, Nagarkatti P, Wang XL, Tang D, Janicki JS, Tian X, Cui T. Identifying panaxynol, a natural activator of nuclear factor erythroid-2 related factor 2 (Nrf2) from American ginseng as a suppressor of inflamed macrophage-induced cardiomyocyte hypertrophy. J Ethnopharmacol. 2015 Jun 20; 168:326-36. PMID: 25882312.
      View in: PubMed
    94. Chen L, Yang S, Zumbrun EE, Guan H, Nagarkatti PS, Nagarkatti M. Resveratrol attenuates lipopolysaccharide-induced acute kidney injury by suppressing inflammation driven by macrophages. Mol Nutr Food Res. 2015 May; 59(5):853-64. PMID: 25643926.
      View in: PubMed
    95. Tomar S, Nagarkatti M, Nagarkatti PS. 3,3'-Diindolylmethane attenuates LPS-mediated acute liver failure by regulating miRNAs to target IRAK4 and suppress Toll-like receptor signalling. Br J Pharmacol. 2015 Apr; 172(8):2133-47. PMID: 25521277.
      View in: PubMed
    96. Singh NP, Abbas IK, Menard M, Singh UP, Zhang J, Nagarkatti P, Nagarkatti M. Exposure to diethylstilbestrol during pregnancy modulates microRNA expression profile in mothers and fetuses reflecting oncogenic and immunological changes. Mol Pharmacol. 2015 May; 87(5):842-54. PMID: 25753120.
      View in: PubMed
    97. Tomar S, Zumbrun EE, Nagarkatti M, Nagarkatti PS. Protective role of cannabinoid receptor 2 activation in galactosamine/lipopolysaccharide-induced acute liver failure through regulation of macrophage polarization and microRNAs. J Pharmacol Exp Ther. 2015 May; 353(2):369-79. PMID: 25749929.
      View in: PubMed
    98. Busbee PB, Nagarkatti M, Nagarkatti PS. Natural indoles, indole-3-carbinol (I3C) and 3,3'-diindolylmethane (DIM), attenuate staphylococcal enterotoxin B-mediated liver injury by downregulating miR-31 expression and promoting caspase-2-mediated apoptosis. PLoS One. 2015; 10(2):e0118506. PMID: 25706292.
      View in: PubMed
    99. Sido JM, Yang X, Nagarkatti PS, Nagarkatti M. ?9-Tetrahydrocannabinol-mediated epigenetic modifications elicit myeloid-derived suppressor cell activation via STAT3/S100A8. J Leukoc Biol. 2015 Apr; 97(4):677-88. PMID: 25713087.
      View in: PubMed
    100. Rao R, Nagarkatti PS, Nagarkatti M. ?(9) Tetrahydrocannabinol attenuates Staphylococcal enterotoxin B-induced inflammatory lung injury and prevents mortality in mice by modulation of miR-17-92 cluster and induction of T-regulatory cells. Br J Pharmacol. 2015 Apr; 172(7):1792-806. PMID: 25425209.
      View in: PubMed
    101. Pourhoseini S, Seth RK, Das S, Dattaroy D, Kadiiska MB, Xie G, Michelotti GA, Nagarkatti M, Diehl AM, Chatterjee S. Upregulation of miR21 and repression of Grhl3 by leptin mediates sinusoidal endothelial injury in experimental nonalcoholic steatohepatitis. PLoS One. 2015; 10(2):e0116780. PMID: 25658689.
      View in: PubMed
    102. Shamran HA, Kadhim HS, Hussain AR, Kareem A, Taub DD, Price RL, Nagarkatti M, Nagarkatti PS, Singh UP. Detection of human cytomegalovirus in different histopathological types of glioma in Iraqi patients. Biomed Res Int. 2015; 2015:642652. PMID: 25710012.
      View in: PubMed
    103. Zumbrun EE, Sido JM, Nagarkatti PS, Nagarkatti M. Epigenetic Regulation of Immunological Alterations Following Prenatal Exposure to Marijuana Cannabinoids and its Long Term Consequences in Offspring. J Neuroimmune Pharmacol. 2015 Jun; 10(2):245-54. PMID: 25618446.
      View in: PubMed
    104. Ou L, Shi Y, Dong W, Liu C, Schmidt TJ, Nagarkatti P, Nagarkatti M, Fan D, Ai W. Kruppel-like factor KLF4 facilitates cutaneous wound healing by promoting fibrocyte generation from myeloid-derived suppressor cells. J Invest Dermatol. 2015 May; 135(5):1425-1434. PMID: 25581502.
      View in: PubMed
    105. Rao R, Nagarkatti P, Nagarkatti M. Role of miRNA in the regulation of inflammatory genes in staphylococcal enterotoxin B-induced acute inflammatory lung injury and mortality. Toxicol Sci. 2015 Apr; 144(2):284-97. PMID: 25564423.
      View in: PubMed
    106. Radwan FF, Hossain A, God JM, Leaphart N, Elvington M, Nagarkatti M, Tomlinson S, Haque A. Reduction of myeloid-derived suppressor cells and lymphoma growth by a natural triterpenoid. J Cell Biochem. 2015 Jan; 116(1):102-14. PMID: 25142864.
      View in: PubMed
    107. Dattaroy D, Pourhoseini S, Das S, Alhasson F, Seth RK, Nagarkatti M, Michelotti GA, Diehl AM, Chatterjee S. Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis. Am J Physiol Gastrointest Liver Physiol. 2015 Feb 15; 308(4):G298-312. PMID: 25501551.
      View in: PubMed
    108. Shi Y, Ou L, Han S, Li M, Pena MM, Pena EA, Liu C, Nagarkatti M, Fan D, Ai W. Deficiency of Kruppel-like factor KLF4 in myeloid-derived suppressor cells inhibits tumor pulmonary metastasis in mice accompanied by decreased fibrocytes. Oncogenesis. 2014 Nov 24; 3:e129. PMID: 25417726.
      View in: PubMed
    109. Singh UP, Murphy AE, Enos RT, Shamran HA, Singh NP, Guan H, Hegde VL, Fan D, Price RL, Taub DD, Mishra MK, Nagarkatti M, Nagarkatti PS. miR-155 deficiency protects mice from experimental colitis by reducing T helper type 1/type 17 responses. Immunology. 2014 Nov; 143(3):478-89. PMID: 24891206.
      View in: PubMed
    110. Zhou J, Chaudhry H, Zhong Y, Ali MM, Perkins LA, Owens WB, Morales JE, McGuire FR, Zumbrun EE, Zhang J, Nagarkatti PS, Nagarkatti M. Dysregulation in microRNA expression in peripheral blood mononuclear cells of sepsis patients is associated with immunopathology. Cytokine. 2015 Jan; 71(1):89-100. PMID: 25265569.
      View in: PubMed
    111. Chakrabarti M, Haque A, Banik NL, Nagarkatti P, Nagarkatti M, Ray SK. Estrogen receptor agonists for attenuation of neuroinflammation and neurodegeneration. Brain Res Bull. 2014 Oct; 109:22-31. PMID: 25245209.
      View in: PubMed
    112. Shamran HA, Hamza SJ, Yaseen NY, Al-Juboory AA, Taub DD, Price RL, Nagarkatti M, Nagarkatti PS, Singh UP. Impact of single nucleotide polymorphism in IL-4, IL-4R genes and systemic concentration of IL-4 on the incidence of glioma in Iraqi patients. Int J Med Sci. 2014; 11(11):1147-53. PMID: 25170298.
      View in: PubMed
    113. Sido JM, Nagarkatti PS, Nagarkatti M. Role of Endocannabinoid Activation of Peripheral CB1 Receptors in the Regulation of Autoimmune Disease. Int Rev Immunol. 2015; 34(5):403-14. PMID: 24911431.
      View in: PubMed
    114. Rouse M, Rao R, Nagarkatti M, Nagarkatti PS. 3,3'-diindolylmethane ameliorates experimental autoimmune encephalomyelitis by promoting cell cycle arrest and apoptosis in activated T cells through microRNA signaling pathways. J Pharmacol Exp Ther. 2014 Aug; 350(2):341-52. PMID: 24898268.
      View in: PubMed
    115. Ma X, Zhou J, Zhong Y, Jiang L, Mu P, Li Y, Singh N, Nagarkatti M, Nagarkatti P. Expression, regulation and function of microRNAs in multiple sclerosis. Int J Med Sci. 2014; 11(8):810-8. PMID: 24936144.
      View in: PubMed
    116. Yang X, Hegde VL, Rao R, Zhang J, Nagarkatti PS, Nagarkatti M. Histone modifications are associated with ?9-tetrahydrocannabinol-mediated alterations in antigen-specific T cell responses. J Biol Chem. 2014 Jul 04; 289(27):18707-18. PMID: 24841204.
      View in: PubMed
    117. Altamemi I, Murphy EA, Catroppo JF, Zumbrun EE, Zhang J, McClellan JL, Singh UP, Nagarkatti PS, Nagarkatti M. Role of microRNAs in resveratrol-mediated mitigation of colitis-associated tumorigenesis in Apc(Min/+) mice. J Pharmacol Exp Ther. 2014 Jul; 350(1):99-109. PMID: 24817032.
      View in: PubMed
    118. Rao R, Rieder SA, Nagarkatti P, Nagarkatti M. Staphylococcal enterotoxin B-induced microRNA-155 targets SOCS1 to promote acute inflammatory lung injury. Infect Immun. 2014 Jul; 82(7):2971-9. PMID: 24778118.
      View in: PubMed
    119. Zhou J, Nagarkatti P, Zhong Y, Ginsberg JP, Singh NP, Zhang J, Nagarkatti M. Dysregulation in microRNA expression is associated with alterations in immune functions in combat veterans with post-traumatic stress disorder. PLoS One. 2014; 9(4):e94075. PMID: 24759737.
      View in: PubMed
    120. Jackson AR, Nagarkatti P, Nagarkatti M. Anandamide attenuates Th-17 cell-mediated delayed-type hypersensitivity response by triggering IL-10 production and consequent microRNA induction. PLoS One. 2014; 9(4):e93954. PMID: 24699635.
      View in: PubMed
    121. Zhang J, Chen YP, Miller KP, Ganewatta MS, Bam M, Yan Y, Nagarkatti M, Decho AW, Tang C. Antimicrobial metallopolymers and their bioconjugates with conventional antibiotics against multidrug-resistant bacteria. J Am Chem Soc. 2014 Apr 02; 136(13):4873-6. PMID: 24628053.
      View in: PubMed
    122. Steiner J, Davis J, McClellan J, Enos R, Carson J, Fayad R, Nagarkatti M, Nagarkatti P, Altomare D, Creek K, Murphy E. Dose-dependent benefits of quercetin on tumorigenesis in the C3(1)/SV40Tag transgenic mouse model of breast cancer. Cancer Biol Ther. 2014; 15(11):1456-67. PMID: 25482952.
      View in: PubMed
    123. Jackson AR, Hegde VL, Nagarkatti PS, Nagarkatti M. Characterization of endocannabinoid-mediated induction of myeloid-derived suppressor cells involving mast cells and MCP-1. J Leukoc Biol. 2014 Apr; 95(4):609-19. PMID: 24319288.
      View in: PubMed
    124. Singh UP, Singh NP, Guan H, Hegde VL, Price RL, Taub DD, Mishra MK, Nagarkatti M, Nagarkatti PS. The severity of experimental autoimmune cystitis can be ameliorated by anti-CXCL10 Ab treatment. PLoS One. 2013; 8(11):e79751. PMID: 24278169.
      View in: PubMed
    125. Hegde VL, Tomar S, Jackson A, Rao R, Yang X, Singh UP, Singh NP, Nagarkatti PS, Nagarkatti M. Distinct microRNA expression profile and targeted biological pathways in functional myeloid-derived suppressor cells induced by ?9-tetrahydrocannabinol in vivo: regulation of CCAAT/enhancer-binding protein a by microRNA-690. J Biol Chem. 2013 Dec 27; 288(52):36810-26. PMID: 24202177.
      View in: PubMed
    126. Busbee PB, Nagarkatti M, Nagarkatti PS. Natural indoles, indole-3-carbinol and 3,3'-diindolymethane, inhibit T cell activation by staphylococcal enterotoxin B through epigenetic regulation involving HDAC expression. Toxicol Appl Pharmacol. 2014 Jan 01; 274(1):7-16. PMID: 24200994.
      View in: PubMed
    127. Chaudhry H, Zhou J, Zhong Y, Ali MM, McGuire F, Nagarkatti PS, Nagarkatti M. Role of cytokines as a double-edged sword in sepsis. In Vivo. 2013 Nov-Dec; 27(6):669-84. PMID: 24292568.
      View in: PubMed
    128. Poudyal D, Cui X, Le PM, Hofseth AB, Windust A, Nagarkatti M, Nagarkatti PS, Schetter AJ, Harris CC, Hofseth LJ. A key role of microRNA-29b for the suppression of colon cancer cell migration by American ginseng. PLoS One. 2013; 8(10):e75034. PMID: 24130681.
      View in: PubMed
    129. Singh UP, Singh NP, Guan H, Busbee B, Price RL, Taub DD, Mishra MK, Fayad R, Nagarkatti M, Nagarkatti PS. The emerging role of leptin antagonist as potential therapeutic option for inflammatory bowel disease. Int Rev Immunol. 2014 Jan; 33(1):23-33. PMID: 23841494.
      View in: PubMed
    130. Rouse M, Singh NP, Nagarkatti PS, Nagarkatti M. Indoles mitigate the development of experimental autoimmune encephalomyelitis by induction of reciprocal differentiation of regulatory T cells and Th17 cells. Br J Pharmacol. 2013 Jul; 169(6):1305-21. PMID: 23586923.
      View in: PubMed
    131. Singh UP, Singh NP, Guan H, Busbee B, Price RL, Taub DD, Mishra MK, Fayad R, Nagarkatti M, Nagarkatti PS. Leptin antagonist ameliorates chronic colitis in IL-10?/? mice. Immunobiology. 2013 Dec; 218(12):1439-51. PMID: 23726523.
      View in: PubMed
    132. Busbee PB, Rouse M, Nagarkatti M, Nagarkatti PS. Use of natural AhR ligands as potential therapeutic modalities against inflammatory disorders. Nutr Rev. 2013 Jun; 71(6):353-69. PMID: 23731446.
      View in: PubMed
    133. Hassuneh MR, Nagarkatti M, Nagarkatti PS. Role of interleukin-10 in the regulation of tumorigenicity of a T cell lymphoma. Leuk Lymphoma. 2013 Apr; 54(4):827-34. PMID: 22946665.
      View in: PubMed
    134. Guan H, Fan D, Mrelashvili D, Hao H, Singh NP, Singh UP, Nagarkatti PS, Nagarkatti M. MicroRNA let-7e is associated with the pathogenesis of experimental autoimmune encephalomyelitis. Eur J Immunol. 2013 Jan; 43(1):104-14. PMID: 23079871.
      View in: PubMed
    135. Chen Y, Wilbon PA, Zhou J, Nagarkatti M, Wang C, Chu F, Tang C. Multifunctional self-fluorescent polymer nanogels for label-free imaging and drug delivery. Chem Commun (Camb). 2013 Jan 11; 49(3):297-9. PMID: 23183550.
      View in: PubMed
    136. Rieder SA, Nagarkatti P, Nagarkatti M. Multiple anti-inflammatory pathways triggered by resveratrol lead to amelioration of staphylococcal enterotoxin B-induced lung injury. Br J Pharmacol. 2012 Nov; 167(6):1244-58. PMID: 22646800.
      View in: PubMed
    137. Mehla R, Bivalkar-Mehla S, Nagarkatti M, Chauhan A. Programming of neurotoxic cofactor CXCL-10 in HIV-1-associated dementia: abrogation of CXCL-10-induced neuro-glial toxicity in vitro by PKC activator. J Neuroinflammation. 2012 Oct 18; 9:239. PMID: 23078780.
      View in: PubMed
    138. Wu Q, Wang W, Li S, Nagarkatti P, Nagarkatti M, Windust A, Wang XL, Tang D, Cui T. American ginseng inhibits vascular smooth muscle cell proliferation via suppressing Jak/Stat pathway. J Ethnopharmacol. 2012 Dec 18; 144(3):782-5. PMID: 23041701.
      View in: PubMed
    139. Singh NP, Singh UP, Guan H, Nagarkatti P, Nagarkatti M. Prenatal exposure to TCDD triggers significant modulation of microRNA expression profile in the thymus that affects consequent gene expression. PLoS One. 2012; 7(9):e45054. PMID: 23024791.
      View in: PubMed
    140. Singh NP, Singh UP, Nagarkatti PS, Nagarkatti M. Prenatal exposure of mice to diethylstilbestrol disrupts T-cell differentiation by regulating Fas/Fas ligand expression through estrogen receptor element and nuclear factor-?B motifs. J Pharmacol Exp Ther. 2012 Nov; 343(2):351-61. PMID: 22888145.
      View in: PubMed
    141. Rouse M, Nagarkatti M, Nagarkatti PS. The role of IL-2 in the activation and expansion of regulatory T-cells and the development of experimental autoimmune encephalomyelitis. Immunobiology. 2013 Apr; 218(4):674-82. PMID: 22954711.
      View in: PubMed
    142. Poudyal D, Cui X, Mai Le P, Davis T, Hofseth AB, Jin Y, Chumanevich AA, Wargovich MJ, Nagarkatti M, Nagarkatti PS, Windust A, Hofseth LJ. A limited role of p53 on the ability of a Hexane fraction of American ginseng to suppress mouse colitis. J Biomed Biotechnol. 2012; 2012:785739. PMID: 22899889.
      View in: PubMed
    143. Saeed AI, Rieder SA, Price RL, Barker J, Nagarkatti P, Nagarkatti M. Acute lung injury induced by Staphylococcal enterotoxin B: disruption of terminal vessels as a mechanism of induction of vascular leak. Microsc Microanal. 2012 Jun; 18(3):445-452. PMID: 22571856.
      View in: PubMed
    144. Guan H, Singh NP, Singh UP, Nagarkatti PS, Nagarkatti M. Resveratrol prevents endothelial cells injury in high-dose interleukin-2 therapy against melanoma. PLoS One. 2012; 7(4):e35650. PMID: 22532866.
      View in: PubMed
    145. Singh UP, Singh NP, Busbee B, Guan H, Singh B, Price RL, Taub DD, Mishra MK, Nagarkatti M, Nagarkatti PS. Alternative medicines as emerging therapies for inflammatory bowel diseases. Int Rev Immunol. 2012 Feb; 31(1):66-84. PMID: 22251008.
      View in: PubMed
    146. Poudyal D, Le PM, Davis T, Hofseth AB, Chumanevich A, Chumanevich AA, Wargovich MJ, Nagarkatti M, Nagarkatti PS, Windust A, Hofseth LJ. A hexane fraction of American ginseng suppresses mouse colitis and associated colon cancer: anti-inflammatory and proapoptotic mechanisms. Cancer Prev Res (Phila). 2012 Apr; 5(4):685-96. PMID: 22293630.
      View in: PubMed
    147. Wang J, Chen YP, Yao K, Wilbon PA, Zhang W, Ren L, Zhou J, Nagarkatti M, Wang C, Chu F, He X, Decho AW, Tang C. Robust antimicrobial compounds and polymers derived from natural resin acids. Chem Commun (Camb). 2012 Jan 21; 48(6):916-8. PMID: 22143352.
      View in: PubMed
    148. Zhou J, Nagarkatti P, Zhong Y, Nagarkatti M. Characterization of T-cell memory phenotype after in vitro expansion of tumor-infiltrating lymphocytes from melanoma patients. Anticancer Res. 2011 Dec; 31(12):4099-109. PMID: 22199267.
      View in: PubMed
    149. Singh UP, Singh NP, Singh B, Price RL, Nagarkatti M, Nagarkatti PS. Cannabinoid receptor-2 (CB2) agonist ameliorates colitis in IL-10(-/-) mice by attenuating the activation of T cells and promoting their apoptosis. Toxicol Appl Pharmacol. 2012 Jan 15; 258(2):256-67. PMID: 22119709.
      View in: PubMed
    150. Zhou J, Nagarkatti PS, Zhong Y, Zhang J, Nagarkatti M. Implications of single nucleotide polymorphisms in CD44 exon 2 for risk of breast cancer. Eur J Cancer Prev. 2011 Sep; 20(5):396-402. PMID: 21804359.
      View in: PubMed
    151. Zhao D, Amria S, Hossain A, Sundaram K, Komlosi P, Nagarkatti M, Haque A. Enhancement of HLA class II-restricted CD4+ T cell recognition of human melanoma cells following treatment with bryostatin-1. Cell Immunol. 2011; 271(2):392-400. PMID: 21903207.
      View in: PubMed
    152. Singh NP, Singh UP, Singh B, Price RL, Nagarkatti M, Nagarkatti PS. Activation of aryl hydrocarbon receptor (AhR) leads to reciprocal epigenetic regulation of FoxP3 and IL-17 expression and amelioration of experimental colitis. PLoS One. 2011; 6(8):e23522. PMID: 21858153.
      View in: PubMed
    153. Lombard C, Hegde VL, Nagarkatti M, Nagarkatti PS. Perinatal exposure to ?9-tetrahydrocannabinol triggers profound defects in T cell differentiation and function in fetal and postnatal stages of life, including decreased responsiveness to HIV antigens. J Pharmacol Exp Ther. 2011 Nov; 339(2):607-17. PMID: 21831965.
      View in: PubMed
    154. Singh UP, Singh NP, Singh B, Hofseth LJ, Taub DD, Price RL, Nagarkatti M, Nagarkatti PS. Role of resveratrol-induced CD11b(+) Gr-1(+) myeloid derived suppressor cells (MDSCs) in the reduction of CXCR3(+) T cells and amelioration of chronic colitis in IL-10(-/-) mice. Brain Behav Immun. 2012 Jan; 26(1):72-82. PMID: 21807089.
      View in: PubMed
    155. Pandey R, Hegde VL, Nagarkatti M, Nagarkatti PS. Targeting cannabinoid receptors as a novel approach in the treatment of graft-versus-host disease: evidence from an experimental murine model. J Pharmacol Exp Ther. 2011 Sep; 338(3):819-28. PMID: 21673072.
      View in: PubMed
    156. Rieder SA, Nagarkatti P, Nagarkatti M. CD1d-independent activation of invariant natural killer T cells by staphylococcal enterotoxin B through major histocompatibility complex class II/T cell receptor interaction results in acute lung injury. Infect Immun. 2011 Aug; 79(8):3141-8. PMID: 21628519.
      View in: PubMed
    157. Guan H, Nagarkatti PS, Nagarkatti M. CD44 Reciprocally regulates the differentiation of encephalitogenic Th1/Th17 and Th2/regulatory T cells through epigenetic modulation involving DNA methylation of cytokine gene promoters, thereby controlling the development of experimental autoimmune encephalomyelitis. J Immunol. 2011 Jun 15; 186(12):6955-64. PMID: 21551360.
      View in: PubMed
    158. Singh NP, Singh UP, Hegde VL, Guan H, Hofseth L, Nagarkatti M, Nagarkatti PS. Resveratrol (trans-3,5,4'-trihydroxystilbene) suppresses EL4 tumor growth by induction of apoptosis involving reciprocal regulation of SIRT1 and NF-?B. Mol Nutr Food Res. 2011 Aug; 55(8):1207-18. PMID: 21520490.
      View in: PubMed
    159. Hegde VL, Nagarkatti PS, Nagarkatti M. Role of myeloid-derived suppressor cells in amelioration of experimental autoimmune hepatitis following activation of TRPV1 receptors by cannabidiol. PLoS One. 2011 Apr 01; 6(4):e18281. PMID: 21483776.
      View in: PubMed
    160. Hegde VL, Nagarkatti M, Nagarkatti PS. Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties. Eur J Immunol. 2010 Dec; 40(12):3358-71. PMID: 21110319.
      View in: PubMed
    161. Ariza ME, Ramakrishnan R, Singh NP, Chauhan A, Nagarkatti PS, Nagarkatti M. Bryostatin-1, a naturally occurring antineoplastic agent, acts as a Toll-like receptor 4 (TLR-4) ligand and induces unique cytokines and chemokines in dendritic cells. J Biol Chem. 2011 Jan 07; 286(1):24-34. PMID: 21036898.
      View in: PubMed
    162. Cui X, Jin Y, Poudyal D, Chumanevich AA, Davis T, Windust A, Hofseth A, Wu W, Habiger J, Pena E, Wood P, Nagarkatti M, Nagarkatti PS, Hofseth L. Mechanistic insight into the ability of American ginseng to suppress colon cancer associated with colitis. Carcinogenesis. 2010 Oct; 31(10):1734-41. PMID: 20729391.
      View in: PubMed
    163. Singh NP, Singh US, Nagarkatti M, Nagarkatti PS. Resveratrol (3,5,4'-trihydroxystilbene) protects pregnant mother and fetus from the immunotoxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Mol Nutr Food Res. 2011 Feb; 55(2):209-19. PMID: 20715097.
      View in: PubMed
    164. Nagarkatti M, Rieder SA, Hegde VL, Kanada S, Nagarkatti P. Do cannabinoids have a therapeutic role in transplantation? Trends Pharmacol Sci. 2010 Aug; 31(8):345-50. PMID: 20591510.
      View in: PubMed
    165. Mehla R, Bivalkar-Mehla S, Zhang R, Handy I, Albrecht H, Giri S, Nagarkatti P, Nagarkatti M, Chauhan A. Bryostatin modulates latent HIV-1 infection via PKC and AMPK signaling but inhibits acute infection in a receptor independent manner. PLoS One. 2010 Jun 16; 5(6):e11160. PMID: 20585398.
      View in: PubMed
    166. Singh UP, Singh NP, Singh B, Mishra MK, Nagarkatti M, Nagarkatti PS, Singh SR. Stem cells as potential therapeutic targets for inflammatory bowel disease. Front Biosci (Schol Ed). 2010 Jun 01; 2:993-1008. PMID: 20515838.
      View in: PubMed
    167. Zhou J, Nagarkatti P, Zhong Y, Nagarkatti M. Immune modulation by chondroitin sulfate and its degraded disaccharide product in the development of an experimental model of multiple sclerosis. J Neuroimmunol. 2010 Jun; 223(1-2):55-64. PMID: 20434781.
      View in: PubMed
    168. Li J, Ichikawa T, Jin Y, Hofseth LJ, Nagarkatti P, Nagarkatti M, Windust A, Cui T. An essential role of Nrf2 in American ginseng-mediated anti-oxidative actions in cardiomyocytes. J Ethnopharmacol. 2010 Jul 20; 130(2):222-30. PMID: 20447451.
      View in: PubMed
    169. Zhou J, Nagarkatti PS, Zhong Y, Creek K, Zhang J, Nagarkatti M. Unique SNP in CD44 intron 1 and its role in breast cancer development. Anticancer Res. 2010 Apr; 30(4):1263-72. PMID: 20530438.
      View in: PubMed
    170. Hofseth LJ, Singh UP, Singh NP, Nagarkatti M, Nagarkatti PS. Taming the beast within: resveratrol suppresses colitis and prevents colon cancer. Aging (Albany NY). 2010 Apr; 2(4):183-4. PMID: 20436227.
      View in: PubMed
    171. Cui X, Jin Y, Hofseth AB, Pena E, Habiger J, Chumanevich A, Poudyal D, Nagarkatti M, Nagarkatti PS, Singh UP, Hofseth LJ. Resveratrol suppresses colitis and colon cancer associated with colitis. Cancer Prev Res (Phila). 2010 Apr; 3(4):549-59. PMID: 20332304.
      View in: PubMed
    172. Jin Y, Hofseth AB, Cui X, Windust AJ, Poudyal D, Chumanevich AA, Matesic LE, Singh NP, Nagarkatti M, Nagarkatti PS, Hofseth LJ. American ginseng suppresses colitis through p53-mediated apoptosis of inflammatory cells. Cancer Prev Res (Phila). 2010 Mar; 3(3):339-47. PMID: 20179294.
      View in: PubMed
    173. Nagarkatti M, Rieder SA, Vakharia D, Nagarkatti PS. Evaluation of apoptosis in immunotoxicity testing. Methods Mol Biol. 2010; 598:241-57. PMID: 19967519.
      View in: PubMed
    174. Singh UP, Singh NP, Singh B, Hofseth LJ, Price RL, Nagarkatti M, Nagarkatti PS. Resveratrol (trans-3,5,4'-trihydroxystilbene) induces silent mating type information regulation-1 and down-regulates nuclear transcription factor-kappaB activation to abrogate dextran sulfate sodium-induced colitis. J Pharmacol Exp Ther. 2010 Mar; 332(3):829-39. PMID: 19940103.
      View in: PubMed
    175. Nagarkatti P, Pandey R, Rieder SA, Hegde VL, Nagarkatti M. Cannabinoids as novel anti-inflammatory drugs. Future Med Chem. 2009 Oct; 1(7):1333-49. PMID: 20191092.
      View in: PubMed
    176. Guan H, Nagarkatti PS, Nagarkatti M. Role of CD44 in the differentiation of Th1 and Th2 cells: CD44-deficiency enhances the development of Th2 effectors in response to sheep RBC and chicken ovalbumin. J Immunol. 2009 Jul 01; 183(1):172-80. PMID: 19542428.
      View in: PubMed
    177. Ichikawa T, Li J, Nagarkatti P, Nagarkatti M, Hofseth LJ, Windust A, Cui T. American ginseng preferentially suppresses STAT/iNOS signaling in activated macrophages. J Ethnopharmacol. 2009 Aug 17; 125(1):145-50. PMID: 19505555.
      View in: PubMed
    178. Rieder SA, Chauhan A, Singh U, Nagarkatti M, Nagarkatti P. Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. Immunobiology. 2010 Aug; 215(8):598-605. PMID: 19457575.
      View in: PubMed
    179. Pandey R, Mousawy K, Nagarkatti M, Nagarkatti P. Endocannabinoids and immune regulation. Pharmacol Res. 2009 Aug; 60(2):85-92. PMID: 19428268.
      View in: PubMed
    180. Pandey R, Hegde VL, Singh NP, Hofseth L, Singh U, Ray S, Nagarkatti M, Nagarkatti PS. Use of cannabinoids as a novel therapeutic modality against autoimmune hepatitis. Vitam Horm. 2009; 81:487-504. PMID: 19647124.
      View in: PubMed
    181. Jin Y, Kotakadi VS, Ying L, Hofseth AB, Cui X, Wood PA, Windust A, Matesic LE, Pena EA, Chiuzan C, Singh NP, Nagarkatti M, Nagarkatti PS, Wargovich MJ, Hofseth LJ. American ginseng suppresses inflammation and DNA damage associated with mouse colitis. Carcinogenesis. 2008 Dec; 29(12):2351-9. PMID: 18802031.
      View in: PubMed
    182. Kotakadi VS, Jin Y, Hofseth AB, Ying L, Cui X, Volate S, Chumanevich A, Wood PA, Price RL, McNeal A, Singh UP, Singh NP, Nagarkatti M, Nagarkatti PS, Matesic LE, Auclair K, Wargovich MJ, Hofseth LJ. Ginkgo biloba extract EGb 761 has anti-inflammatory properties and ameliorates colitis in mice by driving effector T cell apoptosis. Carcinogenesis. 2008 Sep; 29(9):1799-806. PMID: 18567620.
      View in: PubMed
    183. Hegde VL, Hegde S, Cravatt BF, Hofseth LJ, Nagarkatti M, Nagarkatti PS. Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: involvement of regulatory T cells. Mol Pharmacol. 2008 Jul; 74(1):20-33. PMID: 18388242.
      View in: PubMed
    184. Hegde VL, Singh NP, Nagarkatti PS, Nagarkatti M. CD44 mobilization in allogeneic dendritic cell-T cell immunological synapse plays a key role in T cell activation. J Leukoc Biol. 2008 Jul; 84(1):134-42. PMID: 18388297.
      View in: PubMed
    185. Singh NP, Nagarkatti M, Nagarkatti P. Primary peripheral T cells become susceptible to 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated apoptosis in vitro upon activation and in the presence of dendritic cells. Mol Pharmacol. 2008 Jun; 73(6):1722-35. PMID: 18334599.
      View in: PubMed
    186. Ying L, Hofseth AB, Browning DD, Nagarkatti M, Nagarkatti PS, Hofseth LJ. Nitric oxide inactivates the retinoblastoma pathway in chronic inflammation. Cancer Res. 2007 Oct 01; 67(19):9286-93. PMID: 17909036.
      View in: PubMed
    187. Guan H, Nagarkatti PS, Nagarkatti M. Blockade of hyaluronan inhibits IL-2-induced vascular leak syndrome and maintains effectiveness of IL-2 treatment for metastatic melanoma. J Immunol. 2007 Sep 15; 179(6):3715-23. PMID: 17785808.
      View in: PubMed
    188. Singh NP, Hegde VL, Hofseth LJ, Nagarkatti M, Nagarkatti P. Resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis, primarily via induction of apoptosis in T cells involving activation of aryl hydrocarbon receptor and estrogen receptor. Mol Pharmacol. 2007 Dec; 72(6):1508-21. PMID: 17872969.
      View in: PubMed
    189. Lombard C, Nagarkatti M, Nagarkatti P. CB2 cannabinoid receptor agonist, JWH-015, triggers apoptosis in immune cells: potential role for CB2-selective ligands as immunosuppressive agents. Clin Immunol. 2007 Mar; 122(3):259-70. PMID: 17185040.
      View in: PubMed
    190. Singh NP, Nagarkatti M, Nagarkatti PS. Role of dioxin response element and nuclear factor-kappaB motifs in 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated regulation of Fas and Fas ligand expression. Mol Pharmacol. 2007 Jan; 71(1):145-57. PMID: 16940415.
      View in: PubMed
    191. Melencio L, McKallip RJ, Guan H, Ramakrishnan R, Jain R, Nagarkatti PS, Nagarkatti M. Role of CD4(+)CD25(+) T regulatory cells in IL-2-induced vascular leak. Int Immunol. 2006 Oct; 18(10):1461-71. PMID: 16914509.
      View in: PubMed
    192. Jia W, Hegde VL, Singh NP, Sisco D, Grant S, Nagarkatti M, Nagarkatti PS. Delta9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria. Mol Cancer Res. 2006 Aug; 4(8):549-62. PMID: 16908594.
      View in: PubMed
    193. McKallip RJ, Jia W, Schlomer J, Warren JW, Nagarkatti PS, Nagarkatti M. Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression. Mol Pharmacol. 2006 Sep; 70(3):897-908. PMID: 16754784.
      View in: PubMed
    194. Brown N, Nagarkatti M, Nagarkatti PS. Induction of apoptosis in murine fetal thymocytes following perinatal exposure to diethylstilbestrol. Int J Toxicol. 2006 Jan-Feb; 25(1):9-15. PMID: 16510352.
      View in: PubMed
    195. Faulconer L, Camacho I, Nagarkatti M, Nagarkatti PS. Superantigen-primed T cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) replicate poorly following recall encounter. Arch Toxicol. 2006 Mar; 80(3):134-45. PMID: 16189661.
      View in: PubMed
    196. Brown N, Nagarkatti M, Nagarkatti PS. Diethylstilbestrol alters positive and negative selection of T cells in the thymus and modulates T-cell repertoire in the periphery. Toxicol Appl Pharmacol. 2006 Apr 15; 212(2):119-26. PMID: 16122773.
      View in: PubMed
    197. Camacho IA, Singh N, Hegde VL, Nagarkatti M, Nagarkatti PS. Treatment of mice with 2,3,7,8-tetrachlorodibenzo-p-dioxin leads to aryl hydrocarbon receptor-dependent nuclear translocation of NF-kappaB and expression of Fas ligand in thymic stromal cells and consequent apoptosis in T cells. J Immunol. 2005 Jul 01; 175(1):90-103. PMID: 15972635.
      View in: PubMed
    198. Fisher MT, Nagarkatti M, Nagarkatti PS. Aryl hydrocarbon receptor-dependent induction of loss of mitochondrial membrane potential in epididydimal spermatozoa by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol Lett. 2005 Jun 17; 157(2):99-107. PMID: 15836997.
      View in: PubMed
    199. McKallip RJ, Nagarkatti M, Nagarkatti PS. Delta-9-tetrahydrocannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response. J Immunol. 2005 Mar 15; 174(6):3281-9. PMID: 15749859.
      View in: PubMed
    200. Lombard C, Nagarkatti M, Nagarkatti PS. Targeting cannabinoid receptors to treat leukemia: role of cross-talk between extrinsic and intrinsic pathways in Delta9-tetrahydrocannabinol (THC)-induced apoptosis of Jurkat cells. Leuk Res. 2005 Aug; 29(8):915-22. PMID: 15978942.
      View in: PubMed
    201. McKallip RJ, Fisher M, Gunthert U, Szakal AK, Nagarkatti PS, Nagarkatti M. Role of CD44 and its v7 isoform in staphylococcal enterotoxin B-induced toxic shock: CD44 deficiency on hepatic mononuclear cells leads to reduced activation-induced apoptosis that results in increased liver damage. Infect Immun. 2005 Jan; 73(1):50-61. PMID: 15618140.
      View in: PubMed
    202. Wyant TL, Fisher MT, McKallip RJ, Nagarkatti PS, Nagarkatti M, Conrad DH. Mouse B cell activation is inhibited by CD44 cross-linking. Immunol Invest. 2005; 34(4):399-416. PMID: 16304729.
      View in: PubMed
    203. Do Y, Mainali E, Nagarkatti PS, Nagarkatti M. Bryostatin-1 in combination with calcium ionophore promotes the maturation of human umbilical cord-blood monocyte-derived dendritic cells capable of activating neonatal alloreactive T cells. Cell Immunol. 2004 Sep-Oct; 231(1-2):8-13. PMID: 15919364.
      View in: PubMed
    204. Fisher MT, Nagarkatti M, Nagarkatti PS. 2,3,7,8-tetrachlorodibenzo-p-dioxin enhances negative selection of T cells in the thymus but allows autoreactive T cells to escape deletion and migrate to the periphery. Mol Pharmacol. 2005 Jan; 67(1):327-35. PMID: 15492116.
      View in: PubMed
    205. Do Y, Hegde VL, Nagarkatti PS, Nagarkatti M. Bryostatin-1 enhances the maturation and antigen-presenting ability of murine and human dendritic cells. Cancer Res. 2004 Sep 15; 64(18):6756-65. PMID: 15374994.
      View in: PubMed
    206. Do Y, McKallip RJ, Nagarkatti M, Nagarkatti PS. Activation through cannabinoid receptors 1 and 2 on dendritic cells triggers NF-kappaB-dependent apoptosis: novel role for endogenous and exogenous cannabinoids in immunoregulation. J Immunol. 2004 Aug 15; 173(4):2373-82. PMID: 15294950.
      View in: PubMed
    207. Fisher MT, Nagarkatti M, Nagarkatti PS. Combined screening of thymocytes using apoptosis-specific cDNA array and promoter analysis yields novel gene targets mediating TCDD-induced toxicity. Toxicol Sci. 2004 Mar; 78(1):116-24. PMID: 14718646.
      View in: PubMed
    208. Camacho IA, Nagarkatti M, Nagarkatti PS. Evidence for induction of apoptosis in T cells from murine fetal thymus following perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol Sci. 2004 Mar; 78(1):96-106. PMID: 14718643.
      View in: PubMed
    209. Camacho IA, Nagarkatti M, Nagarkatti PS. Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on maternal immune response during pregnancy. Arch Toxicol. 2004 May; 78(5):290-300. PMID: 15146310.
      View in: PubMed
    210. Do Y, Nagarkatti PS, Nagarkatti M. Role of CD44 and hyaluronic acid (HA) in activation of alloreactive and antigen-specific T cells by bone marrow-derived dendritic cells. J Immunother. 2004 Jan-Feb; 27(1):1-12. PMID: 14676629.
      View in: PubMed
    211. Do Y, Rafi-Janajreh AQ, McKallip RJ, Nagarkatti PS, Nagarkatti M. Combined deficiency in CD44 and Fas leads to exacerbation of lymphoproliferative and autoimmune disease. Int Immunol. 2003 Nov; 15(11):1327-40. PMID: 14565931.
      View in: PubMed
    212. Lombard C, McKallip RJ, Hylemon PB, Nagarkatti PS, Nagarkatti M. Fas Ligand-dependent and -independent mechanisms of toxicity induced by T cell lymphomas in lymphoid organs and in the liver. Clin Immunol. 2003 Nov; 109(2):144-53. PMID: 14597213.
      View in: PubMed
    213. McKallip RJ, Fisher M, Do Y, Szakal AK, Gunthert U, Nagarkatti PS, Nagarkatti M. Targeted deletion of CD44v7 exon leads to decreased endothelial cell injury but not tumor cell killing mediated by interleukin-2-activated cytolytic lymphocytes. J Biol Chem. 2003 Oct 31; 278(44):43818-30. PMID: 12904302.
      View in: PubMed
    214. Linzey D, Burroughs J, Hudson L, Marini M, Robertson J, Bacon J, Nagarkatti M, Nagarkatti P. Role of environmental pollutants on immune functions, parasitic infections and limb malformations in marine toads and whistling frogs from Bermuda. Int J Environ Health Res. 2003 Jun; 13(2):125-48. PMID: 12745335.
      View in: PubMed
    215. Do Y, Ryu S, Nagarkatti M, Nagarkatti PS. Role of death receptor pathway in estradiol-induced T-cell apoptosis in vivo. Toxicol Sci. 2002 Nov; 70(1):63-72. PMID: 12388836.
      View in: PubMed
    216. Mustafa A, McKallip RJ, Fisher M, Duncan R, Nagarkatti PS, Nagarkatti M. Regulation of interleukin-2-induced vascular leak syndrome by targeting CD44 using hyaluronic acid and anti-CD44 antibodies. J Immunother. 2002 Nov-Dec; 25(6):476-88. PMID: 12439345.
      View in: PubMed
    217. Zeytun A, McKallip RJ, Fisher M, Camacho I, Nagarkatti M, Nagarkatti PS. Analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced gene expression profile in vivo using pathway-specific cDNA arrays. Toxicology. 2002 Sep 16; 178(3):241-60. PMID: 12167310.
      View in: PubMed
    218. McKallip RJ, Do Y, Fisher MT, Robertson JL, Nagarkatti PS, Nagarkatti M. Role of CD44 in activation-induced cell death: CD44-deficient mice exhibit enhanced T cell response to conventional and superantigens. Int Immunol. 2002 Sep; 14(9):1015-26. PMID: 12202399.
      View in: PubMed
    219. Camacho IA, Nagarkatti M, Nagarkatti PS. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces Fas-dependent activation-induced cell death in superantigen-primed T cells. Arch Toxicol. 2002 Oct; 76(10):570-80. PMID: 12373453.
      View in: PubMed
    220. McKallip RJ, Lombard C, Martin BR, Nagarkatti M, Nagarkatti PS. Delta(9)-tetrahydrocannabinol-induced apoptosis in the thymus and spleen as a mechanism of immunosuppression in vitro and in vivo. J Pharmacol Exp Ther. 2002 Aug; 302(2):451-65. PMID: 12130702.
      View in: PubMed
    221. McKallip RJ, Lombard C, Fisher M, Martin BR, Ryu S, Grant S, Nagarkatti PS, Nagarkatti M. Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. Blood. 2002 Jul 15; 100(2):627-34. PMID: 12091357.
      View in: PubMed
    222. Camacho IA, Hassuneh MR, Nagarkatti M, Nagarkatti PS. Enhanced activation-induced cell death as a mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immunotoxicity in peripheral T cells. Toxicology. 2001 Aug 13; 165(1):51-63. PMID: 11551431.
      View in: PubMed
    223. Okasha SA, Ryu S, Do Y, McKallip RJ, Nagarkatti M, Nagarkatti PS. Evidence for estradiol-induced apoptosis and dysregulated T cell maturation in the thymus. Toxicology. 2001 May 28; 163(1):49-62. PMID: 11376864.
      View in: PubMed
    224. Chen D, McKallip RJ, Zeytun A, Do Y, Lombard C, Robertson JL, Mak TW, Nagarkatti PS, Nagarkatti M. CD44-deficient mice exhibit enhanced hepatitis after concanavalin A injection: evidence for involvement of CD44 in activation-induced cell death. J Immunol. 2001 May 15; 166(10):5889-97. PMID: 11342603.
      View in: PubMed
    225. Zeytun A, Nagarkatti M, Nagarkatti PS. Growth of FasL-bearing tumor cells in syngeneic murine host induces apoptosis and toxicity in Fas(+) organs. Blood. 2000 Mar 15; 95(6):2111-7. PMID: 10706882.
      View in: PubMed
    226. Kamath AB, Camacho I, Nagarkatti PS, Nagarkatti M. Role of Fas-Fas ligand interactions in 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD)-induced immunotoxicity: increased resistance of thymocytes from Fas-deficient (lpr) and Fas ligand-defective (gld) mice to TCDD-induced toxicity. Toxicol Appl Pharmacol. 1999 Oct 15; 160(2):141-55. PMID: 10527913.
      View in: PubMed
    227. Rafi-Janajreh AQ, Chen D, Schmits R, Mak TW, Grayson RL, Sponenberg DP, Nagarkatti M, Nagarkatti PS. Evidence for the involvement of CD44 in endothelial cell injury and induction of vascular leak syndrome by IL-2. J Immunol. 1999 Aug 01; 163(3):1619-27. PMID: 10415067.
      View in: PubMed
    228. Bradley M, Zeytun A, Rafi-Janajreh A, Nagarkatti PS, Nagarkatti M. Role of spontaneous and interleukin-2-induced natural killer cell activity in the cytotoxicity and rejection of Fas+ and Fas- tumor cells. Blood. 1998 Dec 01; 92(11):4248-55. PMID: 9834230.
      View in: PubMed
    229. Rafi AQ, Zeytun A, Bradley MJ, Sponenberg DP, Grayson RL, Nagarkatti M, Nagarkatti PS. Evidence for the involvement of Fas ligand and perforin in the induction of vascular leak syndrome. J Immunol. 1998 Sep 15; 161(6):3077-86. PMID: 9743374.
      View in: PubMed
    230. Pryputniewicz SJ, Nagarkatti M, Nagarkatti PS. Differential induction of apoptosis in activated and resting T cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and its repercussion on T cell responsiveness. Toxicology. 1998 Aug 21; 129(2-3):211-26. PMID: 9772099.
      View in: PubMed
    231. Rafi-Janajreh AQ, Nagarkatti PS, Nagarkatti M. Role of CD44 in CTL and NK cell activity. Front Biosci. 1998 Jul 01; 3:d665-71. PMID: 9634546.
      View in: PubMed
    232. Kamath AB, Nagarkatti PS, Nagarkatti M. Characterization of phenotypic alterations induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin on thymocytes in vivo and its effect on apoptosis. Toxicol Appl Pharmacol. 1998 May; 150(1):117-24. PMID: 9630460.
      View in: PubMed
    233. Zeytun A, Hassuneh M, Nagarkatti M, Nagarkatti PS. Fas-Fas ligand-based interactions between tumor cells and tumor-specific cytotoxic T lymphocytes: a lethal two-way street. Blood. 1997 Sep 01; 90(5):1952-9. PMID: 9292529.
      View in: PubMed
    234. Rafi A, Nagarkatti M, Nagarkatti PS. Hyaluronate-CD44 interactions can induce murine B-cell activation. Blood. 1997 Apr 15; 89(8):2901-8. PMID: 9108410.
      View in: PubMed
    235. Kamath AB, Xu H, Nagarkatti PS, Nagarkatti M. Evidence for the induction of apoptosis in thymocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin in vivo. Toxicol Appl Pharmacol. 1997 Feb; 142(2):367-77. PMID: 9070360.
      View in: PubMed
    236. Hassuneh MR, Nagarkatti PS, Nagarkatti M. Evidence for the participation of interleukin-2 (IL-2) and IL-4 in the regulation of autonomous growth and tumorigenesis of transformed cells of lymphoid origin. Blood. 1997 Jan 15; 89(2):610-20. PMID: 9002965.
      View in: PubMed
    237. Rhile MJ, Nagarkatti M, Nagarkatti PS. Role of Fas apoptosis and MHC genes in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immunotoxicity of T cells. Toxicology. 1996 Jun 17; 110(1-3):153-67. PMID: 8658555.
      View in: PubMed
    238. Nagarkatti M, Nagarkatti PS, Brooks A. Effect of radon on the immune system: alterations in the cellularity and functions of T cells in lymphoid organs of mouse. J Toxicol Environ Health. 1996 Apr 19; 47(6):535-52. PMID: 8614022.
      View in: PubMed
    239. Hammond-McKibben DM, Seth A, Nagarkatti PS, Nagarkatti M. Characterization of factors regulating successful immunotherapy using a tumor-specific cytotoxic T lymphocyte clone: role of interleukin-2, cycling pattern of lytic activity and adhesion molecules. Int J Cancer. 1995 Mar 16; 60(6):828-36. PMID: 7896454.
      View in: PubMed
    240. McKallip RJ, Nagarkatti M, Nagarkatti PS. Immunotoxicity of AZT: inhibitory effect on thymocyte differentiation and peripheral T cell responsiveness to gp120 of human immunodeficiency virus. Toxicol Appl Pharmacol. 1995 Mar; 131(1):53-62. PMID: 7878678.
      View in: PubMed
    241. Nagarkatti M, Hassuneh M, Seth A, Manickasundari K, Nagarkatti PS. Constitutive activation of the interleukin 2 gene in the induction of spontaneous in vitro transformation and tumorigenicity of T cells. Proc Natl Acad Sci U S A. 1994 Aug 02; 91(16):7638-42. PMID: 8052634.
      View in: PubMed
    242. Hammond DM, Nagarkatti PS, Goté LR, Seth A, Hassuneh MR, Nagarkatti M. Double-negative T cells from MRL-lpr/lpr mice mediate cytolytic activity when triggered through adhesion molecules and constitutively express perforin gene. J Exp Med. 1993 Dec 01; 178(6):2225-30. PMID: 8245794.
      View in: PubMed
    243. McKallip RJ, Nagarkatti M, Nagarkatti P. Immunomodulatory properties of AZT. Ann N Y Acad Sci. 1993 Jun 23; 685:464-6. PMID: 8363254.
      View in: PubMed
    244. Kakkanaiah VN, Nagarkatti PS, Nagarkatti M. Murine lymphocytes exhibit heterogeneity in their proliferative responsiveness to calcium ionophore. Cell Mol Biol (Noisy-le-grand). 1992 Aug-Sep; 38(5-6):533-43. PMID: 1483106.
      View in: PubMed
    245. Selvan RS, Nagarkatti PS, Nagarkatti M. Characterization of T lymphocyte clones isolated from BCNU-cured LSA mice. Int J Cell Cloning. 1991 Nov; 9(6):594-605. PMID: 1770232.
      View in: PubMed
    246. Kakkanaiah VN, Nagarkatti M, Bluestone JA, Nagarkatti PS. CD4-CD8- thymocytes from MRL-lpr/lpr mice exhibit abnormal proportions of alpha beta- and gamma delta-TCR+ cells and demonstrate defective responsiveness when activated through the TCR. Cell Immunol. 1991 Oct 15; 137(2):269-82. PMID: 1832583.
      View in: PubMed
    247. Seth A, Gote L, Nagarkatti M, Nagarkatti PS. T-cell-receptor-independent activation of cytolytic activity of cytotoxic T lymphocytes mediated through CD44 and gp90MEL-14. Proc Natl Acad Sci U S A. 1991 Sep 01; 88(17):7877-81. PMID: 1881921.
      View in: PubMed
    248. Dean TN, Kakkanaiah VN, Nagarkatti M, Nagarkatti PS. Immunosuppression by aldicarb of T cell responses to antigen-specific and polyclonal stimuli results from defective IL-1 production by the macrophages. Toxicol Appl Pharmacol. 1990 Dec; 106(3):408-17. PMID: 2260089.
      View in: PubMed
    249. Clary S, Nagarkatti PS, Nagarkatti M. Immunomodulatory effects of nitrosoureas on the phenotype and functions of T cells in the thymus and periphery. Immunopharmacology. 1990 Nov-Dec; 20(3):153-64. PMID: 2149719.
      View in: PubMed
    250. Kakkanaiah VN, Seth A, Nagarkatti M, Nagarkatti PS. Autoreactive T cell clones isolated from normal and autoimmune-susceptible mice exhibit lymphokine secretory and functional properties of both Th1 and Th2 cells. Clin Immunol Immunopathol. 1990 Oct; 57(1):148-62. PMID: 2144221.
      View in: PubMed
    251. Selvan RS, Nagarkatti PS, Nagarkatti M. Role of IL-2, IL-4 and IL-6 in the growth and differentiation of tumor-specific CD4+ T helper and CD8+ T cytotoxic cells. Int J Cancer. 1990 Jun 15; 45(6):1096-104. PMID: 1972141.
      View in: PubMed
    252. Nagarkatti M, Clary SR, Nagarkatti PS. Characterization of tumor-infiltrating CD4+ T cells as Th1 cells based on lymphokine secretion and functional properties. J Immunol. 1990 Jun 15; 144(12):4898-905. PMID: 1972170.
      View in: PubMed
    253. Kakkanaiah VN, Pyle RH, Nagarkatti M, Nagarkatti PS. Evidence for major alterations in the thymocyte subpopulations in murine models of autoimmune diseases. J Autoimmun. 1990 Jun; 3(3):271-88. PMID: 1975741.
      View in: PubMed
    254. Kakkanaiah VN, Nagarkatti M, Nagarkatti PS. Evidence for the existence of distinct heterogeneity among the peripheral CD4-CD8- T cells from MRL-lpr/lpr mice based on the expression of the J11d marker, activation requirements, and functional properties. Cell Immunol. 1990 May; 127(2):442-57. PMID: 2139366.
      View in: PubMed
    255. Seth A, Nagarkatti M, Nagarkatti PS, Subbarao B, Udhayakumar V. Macrophages but not B cells from aged mice are defective in stimulating autoreactive T cells in vitro. Mech Ageing Dev. 1990 Mar 15; 52(2-3):107-24. PMID: 2325428.
      View in: PubMed
    256. Dean TN, Selvan RS, Misra HP, Nagarkatti M, Nagarkatti PS. Aldicarb treatment inhibits the stimulatory activity of macrophages without affecting the T-cell responses in the syngeneic mixed lymphocyte reaction. Int J Immunopharmacol. 1990; 12(3):337-48. PMID: 2139433.
      View in: PubMed
    257. Nagarkatti M, Toney DM, Nagarkatti PS. Immunomodulation by various nitrosoureas and its effect on the survival of the murine host bearing a syngeneic tumor. Cancer Res. 1989 Dec 01; 49(23):6587-92. PMID: 2573418.
      View in: PubMed
    258. Selvan RS, Dean TN, Misra HP, Nagarkatti PS, Nagarkatti M. Aldicarb suppresses macrophage but not natural killer (NK) cell-mediated cytotoxicity of tumor cells. Bull Environ Contam Toxicol. 1989 Nov; 43(5):676-82. PMID: 2804406.
      View in: PubMed
    259. Nagarkatti PS, Seth A, Nagarkatti M, Muthusamy N, Rychlik B, Subbarao B. A specific defect in the proliferative capacity of B cells from old mice stimulated with autoreactive T cells. Cell Immunol. 1989 Apr 15; 120(1):102-13. PMID: 2784718.
      View in: PubMed
    260. Yurochko AD, Nagarkatti PS, Nagarkatti M, Elgert KD. Tumor-induced alteration in macrophage accessory cell activity on autoreactive T cells. Cancer Immunol Immunother. 1989; 30(3):170-6. PMID: 2598186.
      View in: PubMed
    261. Nagarkatti M, Nagarkatti PS. Calcium ionophores at concentrations mitogenic to normal murine T cells inhibit the proliferation of tumor cells in vitro. Cancer Commun. 1989; 1(5):329-34. PMID: 2702038.
      View in: PubMed
    262. Udhayakumar V, Subbarao B, Seth A, Nagarkatti M, Nagarkatti PS. Impaired autoreactive T cell-induced T cell-T cell interaction in aged mice. Cell Immunol. 1988 Oct 15; 116(2):299-307. PMID: 3263214.
      View in: PubMed
    263. Nagarkatti M, Seth A, Nagarkatti PS. Chemotherapy of mice bearing syngeneic tumors with 1,3-bis (2-chloroethyl)-1-nitrosourea is effective only in normal, but not in irradiated or nude, mice: role of L3T4+ (CD4+) and Lyt-2+ (CD8+) T cells. Cell Immunol. 1988 Sep; 115(2):383-92. PMID: 3261638.
      View in: PubMed
    264. Seth A, Pyle RH, Nagarkatti M, Nagarkatti PS. Expression of the J11d marker on peripheral T lymphocytes of MRL-lpr/lpr mice. J Immunol. 1988 Aug 15; 141(4):1120-5. PMID: 2899601.
      View in: PubMed
    265. Nagarkatti PS, Nagarkatti M, Mann LW, Jones LA, Kaplan AM. Characterization of an endogenous Lyt2+ T-suppressor-cell population regulating autoreactive T cells in vitro and in vivo. Cell Immunol. 1988 Mar; 112(1):64-77. PMID: 2964279.
      View in: PubMed
    266. Nagarkatti M, Nagarkatti PS, Kaplan AM. Differential effects of BCNU on T cell, macrophage, natural killer and lymphokine-activated killer cell activities in mice bearing a syngeneic tumor. Cancer Immunol Immunother. 1988; 27(1):38-46. PMID: 3260820.
      View in: PubMed
    267. Nagarkatti M, Kaplan AM. The role of suppressor T cells in BCNU-mediated rejection of a syngeneic tumor. J Immunol. 1985 Aug; 135(2):1510-7. PMID: 3159794.
      View in: PubMed
    268. Nagarkatti PS, Nagarkatti M, Kaplan AM. Normal Lyt-1+2- T cells have the unique capacity to respond to syngeneic autoreactive T cells. Demonstration of a T cell network. J Exp Med. 1985 Jul 01; 162(1):375-80. PMID: 3874260.
      View in: PubMed
    269. Nagarkatti PS, Nagarkatti M. Effect of experimental dengue virus infection on immune response of the host. I. Nature of changes in T suppressor cell activity regulating the B and T cell responses to heterologous antigens. J Gen Virol. 1983 Jul; 64 (Pt 7):1441-7. PMID: 6223130.
      View in: PubMed
    Nagarkatti's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description