Lymphocyte Activation

"Lymphocyte Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.

Descriptor ID	D008213
MeSH Number(s)	E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.450.050.400.545 G12.565
Concept/Terms	Lymphocyte Activation Lymphocyte Activation Activation, Lymphocyte Blast Transformation Blastogenesis Lymphocyte Stimulation Stimulation, Lymphocyte Lymphocyte Transformation Transformation, Lymphoblast Lymphoblast Transformation Transformation, Blast Transformation, Lymphocyte

Below are MeSH descriptors whose meaning is more general than "Lymphocyte Activation".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Diagnosis [E01]
Diagnostic Techniques and Procedures [E01.370]
Clinical Laboratory Techniques [E01.370.225]
Immunologic Tests [E01.370.225.812]
Lymphocyte Activation [E01.370.225.812.482]
Investigative Techniques [E05]
Clinical Laboratory Techniques [E05.200]
Immunologic Tests [E05.200.812]
Lymphocyte Activation [E05.200.812.482]
Immunologic Techniques [E05.478]
Immunologic Tests [E05.478.594]
Lymphocyte Activation [E05.478.594.530]
Biological Sciences [G]
Immune System Phenomena [G12]
Immunity [G12.450]
Adaptive Immunity [G12.450.050]
Immunity, Cellular [G12.450.050.400]
Lymphocyte Activation [G12.450.050.400.545]
Lymphocyte Activation [G12.565]

Below are MeSH descriptors whose meaning is related to "Lymphocyte Activation".

Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Activation".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Lymphocyte Activation" by people in this website by year, and whether "Lymphocyte Activation" was a major or minor topic of these publications.

Bar chart showing 233 publications over 30 distinct years, with a maximum of 19 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	1	2	3
1993	2	3	5
1994	4	4	8
1995	3	0	3
1996	4	9	13
1997	3	2	5
1998	3	7	10
1999	3	8	11
2000	0	4	4
2001	3	3	6
2002	2	6	8
2003	2	3	5
2004	4	15	19
2005	2	5	7
2006	3	5	8
2007	1	3	4
2008	4	9	13
2009	1	8	9
2010	4	6	10
2011	3	6	9
2012	1	4	5
2013	1	6	7
2014	2	5	7
2015	3	9	12
2016	5	5	10
2017	2	4	6
2018	2	10	12
2019	1	6	7
2020	1	4	5
2021	1	1	2

Below are the most recent publications written about "Lymphocyte Activation" by people in Profiles.

Bhattacharya S, Mereness JA, Baran AM, Misra RS, Peterson DR, Ryan RM, Reynolds AM, Pryhuber GS, Mariani TJ. Lymphocyte-Specific Biomarkers Associated With Preterm Birth and Bronchopulmonary Dysplasia. Front Immunol. 2020; 11:563473.

View in: PubMed
Johnson DK, Magoffin W, Myers SJ, Finnell JG, Hancock JC, Orton TS, Persaud SP, Christensen KA, Weber KS. CD4 Inhibits Helper T Cell Activation at Lower Affinity Threshold for Full-Length T Cell Receptors Than Single Chain Signaling Constructs. Front Immunol. 2020; 11:561889.

View in: PubMed
Tran-Nguyen TK, Xue J, Feghali-Bostwick C, Sciurba FC, Kass DJ, Duncan SR. CD70 Activation Decreases Pulmonary Fibroblast Production of Extracellular Matrix Proteins. Am J Respir Cell Mol Biol. 2020 08; 63(2):255-265.

View in: PubMed
Yang X, Bam M, Becker W, Nagarkatti PS, Nagarkatti M. Long Noncoding RNA AW112010 Promotes the Differentiation of Inflammatory T Cells by Suppressing IL-10 Expression through Histone Demethylation. J Immunol. 2020 08 15; 205(4):987-993.

View in: PubMed
Haque A, Samantaray S, Knaryan VH, Capone M, Hossain A, Matzelle D, Chandran R, Shields DC, Farrand AQ, Boger HA, Banik NL. Calpain mediated expansion of CD4+ cytotoxic T cells in rodent models of Parkinson's disease. Exp Neurol. 2020 08; 330:113315.

View in: PubMed
Lopes JE, Fisher JL, Flick HL, Wang C, Sun L, Ernstoff MS, Alvarez JC, Losey HC. ALKS 4230: a novel engineered IL-2 fusion protein with an improved cellular selectivity profile for cancer immunotherapy. J Immunother Cancer. 2020 04; 8(1).

View in: PubMed
Hurst KE, Lawrence KA, Robino RA, Ball LE, Chung D, Thaxton JE. Remodeling Translation Primes CD8+ T-cell Antitumor Immunity. Cancer Immunol Res. 2020 05; 8(5):587-595.

View in: PubMed
Gudi RR, Karumuthil-Melethil S, Perez N, Li G, Vasu C. Engineered Dendritic Cell-Directed Concurrent Activation of Multiple T cell Inhibitory Pathways Induces Robust Immune Tolerance. Sci Rep. 2019 08 19; 9(1):12065.

View in: PubMed
Sanseviero E, O'Brien EM, Karras JR, Shabaneh TB, Aksoy BA, Xu W, Zheng C, Yin X, Xu X, Karakousis GC, Amaravadi RK, Nam B, Turk MJ, Hammerbacher J, Rubinstein MP, Schuchter LM, Mitchell TC, Liu Q, Stone EL. Anti-CTLA-4 Activates Intratumoral NK Cells and Combined with IL15/IL15Ra Complexes Enhances Tumor Control. Cancer Immunol Res. 2019 08; 7(8):1371-1380.

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Jackson L, Li W, Abdul Y, Dong G, Baban B, Ergul A. Diabetic Stroke Promotes a Sexually Dimorphic Expansion of T Cells. Neuromolecular Med. 2019 12; 21(4):445-453.

View in: PubMed

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