 Brain Death
"Brain Death" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. Reversible conditions which mimic this clinical state (e.g., sedative overdose, hypothermia, etc.) are excluded prior to making the determination of brain death. (From Adams et al., Principles of Neurology, 6th ed, pp348-9)
| Descriptor ID |
D001926
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| MeSH Number(s) |
C10.228.140.151 C10.597.606.358.800.200.100 C23.550.260.159
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| Concept/Terms |
Brain Death- Brain Death
- Death, Brain
- Coma Depasse
- Brain Dead
- Brain Deads
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Below are MeSH descriptors whose meaning is more general than "Brain Death".
Below are MeSH descriptors whose meaning is more specific than "Brain Death".
This graph shows the total number of publications written about "Brain Death" by people in this website by year, and whether "Brain Death" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 | | 1997 | 0 | 3 | 3 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2003 | 1 | 1 | 2 | | 2009 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 3 | 0 | 3 | | 2016 | 2 | 0 | 2 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Brain Death" by people in Profiles.
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Cheng Q, Patel K, Lei B, Rucker L, Allen DP, Zhu P, Vasu C, Martins PN, Goddard M, Nadig SN, Atkinson C. Donor pretreatment with nebulized complement C3a receptor antagonist mitigates brain-death induced immunological injury post-lung transplant. Am J Transplant. 2018 10; 18(10):2417-2428.
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Cooper LB, Milano CA, Williams M, Swafford W, Croezen D, Van Bakel AB, Rogers JG, Patel CB. Thyroid hormone use during cardiac transplant organ procurement. Clin Transplant. 2016 12; 30(12):1578-1583.
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Clarke MJ, Fenton KN, Sade RM. Does Declaration of Brain Death Serve the Best Interest of Organ Donors Rather Than Merely Facilitating Organ Transplantation? Ann Thorac Surg. 2016 Jun; 101(6):2053-8.
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DuBay DA, Redden DT, Bryant MK, Dorn DP, Fouad MN, Gray SH, White JA, Locke JE, Meeks CB, Taylor GC, Kilgore ML, Eckhoff DE. Resource utilization associated with procurement of transplantable organs from donors that do not meet OPTN eligible death criteria. Transplantation. 2014 May 27; 97(10):1043-8.
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Sade RM. Consequences of the Dead Donor Rule. Ann Thorac Surg. 2014 Apr; 97(4):1131-2.
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Sade RM, Boan A. The paradox of the dead donor rule: increasing death on the waiting list. Am J Bioeth. 2014; 14(8):21-3.
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Atkinson C, Floerchinger B, Qiao F, Casey S, Williamson T, Moseley E, Stoica S, Goddard M, Ge X, Tullius SG, Tomlinson S. Donor brain death exacerbates complement-dependent ischemia/reperfusion injury in transplanted hearts. Circulation. 2013 Mar 26; 127(12):1290-9.
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Sade RM. Brain death, cardiac death, and the dead donor rule. J S C Med Assoc. 2011 Aug; 107(4):146-9.
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Atkinson C, Varela JC, Tomlinson S. Complement-dependent inflammation and injury in a murine model of brain dead donor hearts. Circ Res. 2009 Nov 20; 105(11):1094-101.
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Stoica SC, Satchithananda DK, Atkinson C, White PA, Redington AN, Goddard M, Kealey T, Large SR. The energy metabolism in the right and left ventricles of human donor hearts across transplantation. Eur J Cardiothorac Surg. 2003 Apr; 23(4):503-12.
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