Neural Tube Defects
"Neural Tube Defects" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)
Descriptor ID |
D009436
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MeSH Number(s) |
C10.500.680 C16.131.666.680
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Concept/Terms |
Neural Tube Defects- Neural Tube Defects
- Defect, Neural Tube
- Defects, Neural Tube
- Neural Tube Defect
- Developmental Neural Tube Defects
- Neural Tube Developmental Defects
- Developmental Defects, Neural Tube
Tethered Cord Syndrome- Tethered Cord Syndrome
- Tethered Cord Syndromes
- Occult Spinal Dysraphism Sequence
- Tethered Spinal Cord Syndrome
- Occult Spinal Dysraphism
- Dysraphism, Occult Spinal
- Dysraphisms, Occult Spinal
- Occult Spinal Dysraphisms
- Spinal Dysraphism, Occult
- Spinal Dysraphisms, Occult
Neurenteric Cyst- Neurenteric Cyst
- Cyst, Neurenteric
- Cysts, Neurenteric
- Neurenteric Cysts
- Neuroenteric Cyst
- Cyst, Neuroenteric
- Cysts, Neuroenteric
- Neuroenteric Cysts
Spinal Cord Myelodysplasia- Spinal Cord Myelodysplasia
- Myelodysplasia, Spinal Cord
- Myelodysplasias, Spinal Cord
- Spinal Cord Myelodysplasias
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Below are MeSH descriptors whose meaning is more general than "Neural Tube Defects".
Below are MeSH descriptors whose meaning is more specific than "Neural Tube Defects".
This graph shows the total number of publications written about "Neural Tube Defects" by people in this website by year, and whether "Neural Tube Defects" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1991 | 0 | 2 | 2 | 1992 | 1 | 0 | 1 | 1993 | 1 | 0 | 1 | 1996 | 1 | 0 | 1 | 1997 | 1 | 0 | 1 | 2000 | 1 | 0 | 1 | 2001 | 1 | 0 | 1 | 2003 | 1 | 0 | 1 | 2005 | 0 | 1 | 1 | 2006 | 0 | 1 | 1 | 2008 | 1 | 0 | 1 | 2010 | 1 | 0 | 1 | 2011 | 1 | 0 | 1 | 2012 | 1 | 1 | 2 | 2013 | 1 | 0 | 1 | 2015 | 2 | 0 | 2 | 2016 | 0 | 1 | 1 | 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Neural Tube Defects" by people in Profiles.
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Rogers LM, Cordero AM, Pfeiffer CM, Hausman DB, Tsang BL, De-Regil LM, Rosenthal J, Razzaghi H, Wong EC, Weakland AP, Bailey LB. Global folate status in women of reproductive age: a systematic review with emphasis on methodological issues. Ann N Y Acad Sci. 2018 11; 1431(1):35-57.
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Spellicy CJ, Norris J, Bend R, Bupp C, Mester P, Reynolds T, Dean J, Peng Y, Alexov E, Schwartz CE, Stevenson RS, J Friez M. Key apoptotic genes APAF1 and CASP9 implicated in recurrent folate-resistant neural tube defects. Eur J Hum Genet. 2018 03; 26(3):420-427.
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Pfeiffer CM, Sternberg MR, Hamner HC, Crider KS, Lacher DA, Rogers LM, Bailey RL, Yetley EA. Applying inappropriate cutoffs leads to misinterpretation of folate status in the US population. Am J Clin Nutr. 2016 12; 104(6):1607-1615.
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Cordero AM, Crider KS, Rogers LM, Cannon MJ, Berry RJ. Optimal serum and red blood cell folate concentrations in women of reproductive age for prevention of neural tube defects: World Health Organization guidelines. MMWR Morb Mortal Wkly Rep. 2015 Apr 24; 64(15):421-3.
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Taylor CM, Atkinson C, Penfold C, Bhattacharya S, Campbell D, Davey Smith G, Leary S, Ness A. Folic acid in pregnancy and mortality from cancer and cardiovascular disease: further follow-up of the Aberdeen folic acid supplementation trial. J Epidemiol Community Health. 2015 Aug; 69(8):789-94.
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Bond S. Maternal use of opioids near conception may increase risk of neural tube defects. J Midwifery Womens Health. 2014 Jan-Feb; 59(1):101-3.
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Strickland KC, Krupenko NI, Krupenko SA. Molecular mechanisms underlying the potentially adverse effects of folate. Clin Chem Lab Med. 2013 Mar 01; 51(3):607-16.
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McMahon DM, Liu J, Zhang H, Torres ME, Best RG. Maternal obesity, folate intake, and neural tube defects in offspring. Birth Defects Res A Clin Mol Teratol. 2013 Feb; 97(2):115-22.
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Mooney JF, Glazier SS, Barfield WR. Concurrent orthopedic and neurosurgical procedures in pediatric patients with spinal deformity. J Pediatr Orthop B. 2012 Nov; 21(6):602-5.
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Singh CK, Kumar A, LaVoie HA, DiPette DJ, Singh US. Resveratrol prevents impairment in activation of retinoic acid receptors and MAP kinases in the embryos of a rodent model of diabetic embryopathy. Reprod Sci. 2012 Sep; 19(9):949-61.
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