Acetylcysteine

"Acetylcysteine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to reduce the viscosity of mucous secretions. It has also been shown to have antiviral effects in patients with HIV due to inhibition of viral stimulation by reactive oxygen intermediates.

Descriptor ID	D000111
MeSH Number(s)	D02.886.030.230.259 D12.125.166.230.259
Concept/Terms	Acetylcysteine Acetylcysteine N-Acetyl-L-cysteine N Acetyl L cysteine N-Acetylcysteine N Acetylcysteine Mercapturic Acid Acid, Mercapturic Solmucol Solmucol Genac Acemuc Acemuc Acetabs Acetabs Acetylcystein AL Acetylcystein AL NAC AL Acetylcystein Atid Acetylcystein Atid Acetylcystein Heumann Acetylcystein Heumann Acetylcystein Trom Acetylcystein Trom Acetylcysteine Hydrochloride Acetylcysteine Hydrochloride Hydrochloride, Acetylcysteine Acetylcysteine Sodium Acetylcysteine Sodium Sodium, Acetylcysteine Acetylcysteine, Monosodium Salt Monosodium Salt Acetylcysteine Acetylcysteine Zinc Acetylcysteine Zinc Zinc, Acetylcysteine Acetylcysteine, (D)-Isomer Acetylcysteine, (D)-Isomer Acetylcysteine, (DL)-Isomer Acetylcysteine, (DL)-Isomer Acetylcysteine, Monoammonium Salt Acetylcysteine, Monoammonium Salt Monoammonium Salt Acetylcysteine Acetyst Acetyst Acétylcystéine GNR Acétylcystéine GNR Airbron Airbron Alveolex Alveolex Bromuc Azubronchin Azubronchin Bisolvon NAC Bisolvon NAC NAC, Bisolvon Broncho-Fips Broncho-Fips Broncho Fips BronchoFips Broncholysin Broncholysin Broncoclar Broncoclar Codotussyl Codotussyl Cystamucil Cystamucil Dampo Mucopect Dampo Mucopect Mucopect, Dampo durabronchal durabronchal Larylin NAC Eurespiran Eurespiran Exomuc Exomuc Fluimucil Fluimucil NAC Zambon Zambon, NAC Fabrol Fabrol Fluprowit Fluprowit Optipect Hustengetränk Hustengetränk, Optipect Muco Sanigen Sanigen, Muco Frekatuss Frekatuss Jenacystein Jenacystein Jenapharm Lantamed Lantamed Lindocetyl Lindocetyl M-Pectil M-Pectil M Pectil MPectil mentopin Acetylcystein mentopin Acetylcystein Acetylcystein, mentopin Muciteran Muciteran Mucomyst Mucomyst Acetylin Mucosil Mucosil Mucosol Mucosolvin Mucosolvin Siccoral Siccoral Siran Ilube Ilube Hoestil Hoestil acebraus acebraus

Below are MeSH descriptors whose meaning is more general than "Acetylcysteine".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Sulfur Compounds [D02.886]
Amino Acids, Sulfur [D02.886.030]
Cysteine [D02.886.030.230]
Acetylcysteine [D02.886.030.230.259]
Amino Acids, Peptides, and Proteins [D12]
Amino Acids [D12.125]
Amino Acids, Sulfur [D12.125.166]
Cysteine [D12.125.166.230]
Acetylcysteine [D12.125.166.230.259]

Below are MeSH descriptors whose meaning is related to "Acetylcysteine".

Below are MeSH descriptors whose meaning is more specific than "Acetylcysteine".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Acetylcysteine" by people in this website by year, and whether "Acetylcysteine" was a major or minor topic of these publications.

Bar chart showing 106 publications over 24 distinct years, with a maximum of 9 publications in 2014 and 2015 and 2017 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1998	1	4	5
1999	0	1	1
2000	0	1	1
2001	0	2	2
2002	2	0	2
2003	3	1	4
2004	4	3	7
2005	2	0	2
2006	3	1	4
2007	4	2	6
2008	2	1	3
2009	2	2	4
2010	2	1	3
2011	4	0	4
2012	3	3	6
2013	2	2	4
2014	7	2	9
2015	4	5	9
2016	7	0	7
2017	8	1	9
2018	8	1	9
2019	3	0	3
2020	1	0	1

Below are the most recent publications written about "Acetylcysteine" by people in Profiles.

Maier A, Dharan A, Oliver G, Berk M, Redston S, Back SE, Kalivas P, Ng C, Kanaan RA. A multi-centre, double-blind, 12-week, randomized, placebo-controlled trial to assess the efficacy of adjunctive N-Acetylcysteine for treatment-resistant PTSD: a study protocol. BMC Psychiatry. 2020 08 06; 20(1):397.

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Tomko RL, Baker NL, Hood CO, Gilmore AK, McClure EA, Squeglia LM, McRae-Clark AL, Sonne SC, Gray KM. Depressive symptoms and cannabis use in a placebo-controlled trial of N-Acetylcysteine for adult cannabis use disorder. Psychopharmacology (Berl). 2020 Feb; 237(2):479-490.

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Goenaga J, Powell GL, Leyrer-Jackson JM, Piña J, Phan S, Prakapenka AV, Koebele SV, Namba MD, McClure EA, Bimonte-Nelson HA, Gipson CD. N-acetylcysteine yields sex-specific efficacy for cue-induced reinstatement of nicotine seeking. Addict Biol. 2020 01; 25(1):e12711.

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Powell GL, Leyrer-Jackson JM, Goenaga J, Namba MD, Piña J, Spencer S, Stankeviciute N, Schwartz D, Allen NP, Del Franco AP, McClure EA, Olive MF, Gipson CD. Chronic treatment with N-acetylcysteine decreases extinction responding and reduces cue-induced nicotine-seeking. Physiol Rep. 2019 01; 7(1):e13958.

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Kalivas PW, Spencer S. Reply to: N-Acetylcysteine in Treatment of Substance Use Disorders. Biol Psychiatry. 2019 06 01; 85(11):e61.

View in: PubMed
Womersley JS, Townsend DM, Kalivas PW, Uys JD. Targeting redox regulation to treat substance use disorder using N-acetylcysteine Eur J Neurosci. 2019 08; 50(3):2538-2551.

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McClure EA, Baker NL, Sonne SC, Ghitza UE, Tomko RL, Montgomery L, Babalonis S, Terry GE, Gray KM. Tobacco use during cannabis cessation: Use patterns and impact on abstinence in a National Drug Abuse Treatment Clinical Trials Network study. Drug Alcohol Depend. 2018 11 01; 192:59-66.

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Morley KC, Baillie A, Van Den Brink W, Chitty KE, Brady K, Back SE, Seth D, Sutherland G, Leggio L, Haber PS. N-acetyl cysteine in the treatment of alcohol use disorder in patients with liver disease: Rationale for further research. Expert Opin Investig Drugs. 2018 08; 27(8):667-675.

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Tomko RL, Gilmore AK, Gray KM. The role of depressive symptoms in treatment of adolescent cannabis use disorder with N-Acetylcysteine. Addict Behav. 2018 10; 85:26-30.

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Hodebourg R, Murray JE, Fouyssac M, Puaud M, Everitt BJ, Belin D. Heroin seeking becomes dependent on dorsal striatal dopaminergic mechanisms and can be decreased by N-acetylcysteine. Eur J Neurosci. 2019 08; 50(3):2036-2044.

View in: PubMed

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