"Glutathione" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
| Descriptor ID |
D005978
|
| MeSH Number(s) |
D12.644.456.448
|
| Concept/Terms |
Glutathione- Glutathione
- gamma-L-Glutamyl-L-Cysteinylglycine
- gamma L Glutamyl L Cysteinylglycine
- gamma-L-Glu-L-Cys-Gly
- gamma L Glu L Cys Gly
|
Below are MeSH descriptors whose meaning is more general than "Glutathione".
Below are MeSH descriptors whose meaning is more specific than "Glutathione".
This graph shows the total number of publications written about "Glutathione" by people in this website by year, and whether "Glutathione" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 4 | 2 | 6 |
| 1993 | 1 | 2 | 3 |
| 1994 | 1 | 4 | 5 |
| 1995 | 2 | 5 | 7 |
| 1996 | 8 | 3 | 11 |
| 1997 | 3 | 1 | 4 |
| 1998 | 4 | 3 | 7 |
| 1999 | 2 | 3 | 5 |
| 2000 | 2 | 2 | 4 |
| 2001 | 2 | 3 | 5 |
| 2002 | 2 | 2 | 4 |
| 2003 | 3 | 4 | 7 |
| 2004 | 1 | 6 | 7 |
| 2005 | 3 | 6 | 9 |
| 2006 | 5 | 6 | 11 |
| 2007 | 2 | 7 | 9 |
| 2008 | 4 | 2 | 6 |
| 2009 | 3 | 4 | 7 |
| 2010 | 1 | 8 | 9 |
| 2011 | 5 | 3 | 8 |
| 2012 | 1 | 3 | 4 |
| 2013 | 3 | 3 | 6 |
| 2014 | 2 | 6 | 8 |
| 2015 | 2 | 1 | 3 |
| 2016 | 2 | 6 | 8 |
| 2017 | 0 | 1 | 1 |
| 2018 | 5 | 2 | 7 |
| 2019 | 3 | 0 | 3 |
| 2021 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Glutathione" by people in Profiles.
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Zhang J, Ye ZW, Janssen-Heininger Y, Townsend DM, Tew KD. Development of Telintra as an Inhibitor of Glutathione S-Transferase P. Handb Exp Pharmacol. 2021; 264:71-91.
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Prisciandaro JJ, Mikkelsen M, Saleh MG, Edden RAE. An evaluation of the reproducibility of 1H-MRS GABA and GSH levels acquired in healthy volunteers with J-difference editing sequences at varying echo times. Magn Reson Imaging. 2020 01; 65:109-113.
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Kruyer A, Ball LE, Townsend DM, Kalivas PW, Uys JD. Post-translational S-glutathionylation of cofilin increases actin cycling during cocaine seeking. PLoS One. 2019; 14(9):e0223037.
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Reginald-Opara JN, Svirskis D, O'Carroll SJ, Sreebhavan S, Dean JM, Wu Z. Optimisation of glutathione conjugation to liposomes quantified with a validated HPLC assay. Int J Pharm. 2019 Aug 15; 567:118451.
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Wiegand MJ, Kubacki GW, Gilbert JL. Electrochemical potential zone of viability on CoCrMo surfaces is affected by cell type: Macrophages under cathodic bias are more resistant to killing. J Biomed Mater Res A. 2019 03; 107(3):526-534.
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Womersley JS, Townsend DM, Kalivas PW, Uys JD. Targeting redox regulation to treat substance use disorder using N-acetylcysteine Eur J Neurosci. 2019 08; 50(3):2538-2551.
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Song JH, Singh N, Luevano LA, Padi SKR, Okumura K, Olive V, Black SM, Warfel NA, Goodrich DW, Kraft AS. Mechanisms Behind Resistance to PI3K Inhibitor Treatment Induced by the PIM Kinase. . 2018 12; 17(12):2710-2721.
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Zhang J, Ye ZW, Singh S, Townsend DM, Tew KD. An evolving understanding of the S-glutathionylation cycle in pathways of redox regulation. Free Radic Biol Med. 2018 05 20; 120:204-216.
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Moss HG, Brown TR, Wiest DB, Jenkins DD. N-Acetylcysteine rapidly replenishes central nervous system glutathione measured via magnetic resonance spectroscopy in human neonates with hypoxic-ischemic encephalopathy. J Cereb Blood Flow Metab. 2018 06; 38(6):950-958.
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Zhang J, Ye ZW, Chen W, Manevich Y, Mehrotra S, Ball L, Janssen-Heininger Y, Tew KD, Townsend DM. S-Glutathionylation of estrogen receptor a affects dendritic cell function. J Biol Chem. 2018 03 23; 293(12):4366-4380.