 Receptors, Opioid, kappa
"Receptors, Opioid, kappa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of opioid receptors recognized by its pharmacological profile. Kappa opioid receptors bind dynorphins with a higher affinity than endorphins which are themselves preferred to enkephalins.
| Descriptor ID |
D017473
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| MeSH Number(s) |
D12.776.543.750.100.620.400 D12.776.543.750.720.600.610.400 D12.776.543.750.750.555.610.400
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| Concept/Terms |
Receptors, Opioid, kappa- Receptors, Opioid, kappa
- Opioid Receptors, kappa
- kappa Opioid Receptors
- Receptors, kappa Opioid
- Receptors, kappa
- kappa Receptor
- Receptor, kappa
- kappa Receptors
- kappa Opioid Receptor
- Opioid Receptor, kappa
- Receptor, kappa Opioid
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Opioid, kappa".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Opioid [D12.776.543.750.100.620]
- Receptors, Opioid, kappa [D12.776.543.750.100.620.400]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Opioid [D12.776.543.750.720.600.610]
- Receptors, Opioid, kappa [D12.776.543.750.720.600.610.400]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Opioid [D12.776.543.750.750.555.610]
- Receptors, Opioid, kappa [D12.776.543.750.750.555.610.400]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Opioid, kappa".
This graph shows the total number of publications written about "Receptors, Opioid, kappa" by people in this website by year, and whether "Receptors, Opioid, kappa" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 2 | 1 | 3 | | 2000 | 2 | 0 | 2 | | 2001 | 5 | 0 | 5 | | 2002 | 3 | 0 | 3 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2008 | 1 | 2 | 3 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 2 | 0 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Opioid, kappa" by people in Profiles.
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Beck TC, Reichel CM, Helke KL, Bhadsavle SS, Dix TA. Non-addictive orally-active kappa opioid agonists for the treatment of peripheral pain in rats. Eur J Pharmacol. 2019 Aug 05; 856:172396.
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Anderson RI, Lopez MF, Griffin WC, Haun HL, Bloodgood DW, Pati D, Boyt KM, Kash TL, Becker HC. Dynorphin-kappa opioid receptor activity in the central amygdala modulates binge-like alcohol drinking in mice. Neuropsychopharmacology. 2019 05; 44(6):1084-1092.
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Conway SM, Puttick D, Russell S, Potter D, Roitman MF, Chartoff EH. Females are less sensitive than males to the motivational- and dopamine-suppressing effects of kappa opioid receptor activation. Neuropharmacology. 2019 03 01; 146:231-241.
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Heinsbroek JA, Furbish AB, Peters J. A single, extinction-based treatment with a kappa opioid receptor agonist elicits a long-term reduction in cocaine relapse. Neuropsychopharmacology. 2018 06; 43(7):1492-1497.
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Anderson RI, Becker HC. Role of the Dynorphin/Kappa Opioid Receptor System in the Motivational Effects of Ethanol. Alcohol Clin Exp Res. 2017 Aug; 41(8):1402-1418.
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Sundaramurthy S, Annamalai B, Samuvel DJ, Shippenberg TS, Jayanthi LD, Ramamoorthy S. Modulation of serotonin transporter function by kappa-opioid receptor ligands. Neuropharmacology. 2017 02; 113(Pt A):281-292.
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Dennis TS, Beck KD, Cominski TP, Bobzean SAM, Kuzhikandathil EV, Servatius RJ, Perrotti LI. Exposure to morphine-associated cues increases mu opioid receptor mRNA expression in the nucleus accumbens of Wistar Kyoto rats. Behav Brain Res. 2016 10 15; 313:208-213.
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Rose JH, Karkhanis AN, Chen R, Gioia D, Lopez MF, Becker HC, McCool BA, Jones SR. Supersensitive Kappa Opioid Receptors Promotes Ethanol Withdrawal-Related Behaviors and Reduce Dopamine Signaling in the Nucleus Accumbens. Int J Neuropsychopharmacol. 2016 05; 19(5).
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Scholpa NE, Briggs SB, Wagner JJ, Cummings BS. Cyclin-Dependent Kinase Inhibitor 1a (p21) Modulates Response to Cocaine and Motivated Behaviors. J Pharmacol Exp Ther. 2016 Apr; 357(1):56-65.
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Chartoff EH, Ebner SR, Sparrow A, Potter D, Baker PM, Ragozzino ME, Roitman MF. Relative Timing Between Kappa Opioid Receptor Activation and Cocaine Determines the Impact on Reward and Dopamine Release. Neuropsychopharmacology. 2016 Mar; 41(4):989-1002.
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