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Ana Pocivavsek

TitleASST PROFESSOR-USC
InstitutionUniversity of South Carolina School of Medicine
DepartmentMDC PHARM/PHYS & NEURO
AddressMEDICAL V.A. #1
Columbia, South Carolina 29209
Phone(803)216-3509
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Pocivavsek A, Elmer GI, Schwarcz R. Inhibition of kynurenine aminotransferase II attenuates hippocampus-dependent memory deficit in adult rats treated prenatally with kynurenine. Hippocampus. 2019 02; 29(2):73-77. PMID: 30311334.
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    2. Baratta AM, Viechweg SS, Mong JA, Pocivavsek A. A High-performance Liquid Chromatography Measurement of Kynurenine and Kynurenic Acid: Relating Biochemistry to Cognition and Sleep in Rats. J Vis Exp. 2018 08 19; (138). PMID: 30176006.
      View in: PubMed
    3. Notarangelo FM, Pocivavsek A, Schwarcz R. Exercise Your Kynurenines to Fight Depression. Trends Neurosci. 2018 08; 41(8):491-493. PMID: 30053952.
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    4. Glassman M, Wehring HJ, Pocivavsek A, Sullivan KM, Rowland LM, McMahon RP, Chiappelli J, Liu F, Kelly DL. Peripheral Cortisol and Inflammatory Response to a Psychosocial Stressor in People with Schizophrenia. J Neuropsychiatry (Foster City). 2018; 2(2). PMID: 30801048.
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    5. Baratta AM, Buck SA, Buchla AD, Fabian CB, Chen S, Mong JA, Pocivavsek A. Sex Differences in Hippocampal Memory and Kynurenic Acid Formation Following Acute Sleep Deprivation in Rats. Sci Rep. 2018 05 03; 8(1):6963. PMID: 29725029.
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    6. Chiappelli J, Rowland LM, Notarangelo FM, Wijtenburg SA, Thomas MAR, Pocivavsek A, Jones A, Wisner K, Kochunov P, Schwarcz R, Hong LE. Salivary kynurenic acid response to psychological stress: inverse relationship to cortical glutamate in schizophrenia. Neuropsychopharmacology. 2018 07; 43(8):1706-1711. PMID: 29728648.
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    7. Chiappelli J, Notarangelo FM, Pocivavsek A, Thomas MAR, Rowland LM, Schwarcz R, Hong LE. Influence of plasma cytokines on kynurenine and kynurenic acid in schizophrenia. Neuropsychopharmacology. 2018 07; 43(8):1675-1680. PMID: 29520060.
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    8. Pocivavsek A, Rowland LM. Basic Neuroscience Illuminates Causal Relationship Between Sleep and Memory: Translating to Schizophrenia. Schizophr Bull. 2018 01 13; 44(1):7-14. PMID: 29136236.
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    9. Hahn B, Reneski CH, Pocivavsek A, Schwarcz R. Prenatal kynurenine treatment in rats causes schizophrenia-like broad monitoring deficits in adulthood. Psychopharmacology (Berl). 2018 03; 235(3):651-661. PMID: 29128872.
      View in: PubMed
    10. Pocivavsek A, Baratta AM, Mong JA, Viechweg SS. Acute Kynurenine Challenge Disrupts Sleep-Wake Architecture and Impairs Contextual Memory in Adult Rats. Sleep. 2017 11 01; 40(11). PMID: 29029302.
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    11. Goeden N, Notarangelo FM, Pocivavsek A, Beggiato S, Bonnin A, Schwarcz R. Prenatal Dynamics of Kynurenine Pathway Metabolism in Mice: Focus on Kynurenic Acid. Dev Neurosci. 2017; 39(6):519-528. PMID: 29080891.
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    12. Erhardt S, Pocivavsek A, Repici M, Liu XC, Imbeault S, Maddison DC, Thomas MAR, Smalley JL, Larsson MK, Muchowski PJ, Giorgini F, Schwarcz R. Adaptive and Behavioral Changes in Kynurenine 3-Monooxygenase Knockout Mice: Relevance to Psychotic Disorders. Biol Psychiatry. 2017 Nov 15; 82(10):756-765. PMID: 28187857.
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    13. Clark SM, Pocivavsek A, Nicholson JD, Notarangelo FM, Langenberg P, McMahon RP, Kleinman JE, Hyde TM, Stiller J, Postolache TT, Schwarcz R, Tonelli LH. Reduced kynurenine pathway metabolism and cytokine expression in the prefrontal cortex of depressed individuals. J Psychiatry Neurosci. 2016 10; 41(6):386-394. PMID: 27070351.
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    14. Pershing ML, Phenis D, Valentini V, Pocivavsek A, Lindquist DH, Schwarcz R, Bruno JP. Prenatal kynurenine exposure in rats: age-dependent changes in NMDA receptor expression and conditioned fear responding. Psychopharmacology (Berl). 2016 Oct; 233(21-22):3725-3735. PMID: 27527585.
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    15. Notarangelo FM, Pocivavsek A. Elevated kynurenine pathway metabolism during neurodevelopment: Implications for brain and behavior. Neuropharmacology. 2017 Jan; 112(Pt B):275-285. PMID: 26944732.
      View in: PubMed
    16. Pershing ML, Bortz DM, Pocivavsek A, Fredericks PJ, Jørgensen CV, Vunck SA, Leuner B, Schwarcz R, Bruno JP. Elevated levels of kynurenic acid during gestation produce neurochemical, morphological, and cognitive deficits in adulthood: implications for schizophrenia. Neuropharmacology. 2015 Mar; 90:33-41. PMID: 25446576.
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    17. Chiappelli J, Pocivavsek A, Nugent KL, Notarangelo FM, Kochunov P, Rowland LM, Schwarcz R, Hong LE. Stress-induced increase in kynurenic acid as a potential biomarker for patients with schizophrenia and distress intolerance. JAMA Psychiatry. 2014 Jul 01; 71(7):761-8. PMID: 24806441.
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    18. Pocivavsek A, Thomas MA, Elmer GI, Bruno JP, Schwarcz R. Continuous kynurenine administration during the prenatal period, but not during adolescence, causes learning and memory deficits in adult rats. Psychopharmacology (Berl). 2014 Jul; 231(14):2799-809. PMID: 24590052.
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    19. Wu HQ, Okuyama M, Kajii Y, Pocivavsek A, Bruno JP, Schwarcz R. Targeting kynurenine aminotransferase II in psychiatric diseases: promising effects of an orally active enzyme inhibitor. Schizophr Bull. 2014 Mar; 40 Suppl 2:S152-8. PMID: 24562494.
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    20. Alexander KS, Pocivavsek A, Wu HQ, Pershing ML, Schwarcz R, Bruno JP. Early developmental elevations of brain kynurenic acid impair cognitive flexibility in adults: reversal with galantamine. Neuroscience. 2013 May 15; 238:19-28. PMID: 23395862.
      View in: PubMed
    21. Pocivavsek A, Wu HQ, Elmer GI, Bruno JP, Schwarcz R. Pre- and postnatal exposure to kynurenine causes cognitive deficits in adulthood. Eur J Neurosci. 2012 May; 35(10):1605-12. PMID: 22515201.
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    22. Pocivavsek A, Wu HQ, Potter MC, Elmer GI, Pellicciari R, Schwarcz R. Fluctuations in endogenous kynurenic acid control hippocampal glutamate and memory. Neuropsychopharmacology. 2011 Oct; 36(11):2357-67. PMID: 21796108.
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    23. Loane DJ, Washington PM, Vardanian L, Pocivavsek A, Hoe HS, Duff KE, Cernak I, Rebeck GW, Faden AI, Burns MP. Modulation of ABCA1 by an LXR agonist reduces ß-amyloid levels and improves outcome after traumatic brain injury. J Neurotrauma. 2011 Feb; 28(2):225-36. PMID: 21175399.
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    24. Pocivavsek A, Rebeck GW. Inhibition of c-Jun N-terminal kinase increases apoE expression in vitro and in vivo. Biochem Biophys Res Commun. 2009 Sep 25; 387(3):516-20. PMID: 19615334.
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    25. Pocivavsek A, Mikhailenko I, Strickland DK, Rebeck GW. Microglial low-density lipoprotein receptor-related protein 1 modulates c-Jun N-terminal kinase activation. J Neuroimmunol. 2009 Sep 29; 214(1-2):25-32. PMID: 19586665.
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    26. Liu Y, Pocivavsek A, Papadopoulos V. Dehydroepiandrosterone formation is independent of cytochrome P450 17alpha-hydroxylase/17, 20 lyase activity in the mouse brain. J Steroid Biochem Mol Biol. 2009 Jul; 115(3-5):86-90. PMID: 19500726.
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    27. Loane DJ, Pocivavsek A, Moussa CE, Thompson R, Matsuoka Y, Faden AI, Rebeck GW, Burns MP. Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury. Nat Med. 2009 Apr; 15(4):377-9. PMID: 19287391.
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    28. Pocivavsek A, Burns MP, Rebeck GW. Low-density lipoprotein receptors regulate microglial inflammation through c-Jun N-terminal kinase. Glia. 2009 Mar; 57(4):444-53. PMID: 18803301.
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    29. Hoe HS, Pocivavsek A, Dai H, Chakraborty G, Harris DC, Rebeck GW. Effects of apoE on neuronal signaling and APP processing in rodent brain. Brain Res. 2006 Sep 27; 1112(1):70-9. PMID: 16905123.
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    30. Pocivavsek A, Icenogle L, Levin ED. Ventral hippocampal alpha7 and alpha4beta2 nicotinic receptor blockade and clozapine effects on memory in female rats. Psychopharmacology (Berl). 2006 Nov; 188(4):597-604. PMID: 16715255.
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    31. Hoe HS, Pocivavsek A, Chakraborty G, Fu Z, Vicini S, Ehlers MD, Rebeck GW. Apolipoprotein E receptor 2 interactions with the N-methyl-D-aspartate receptor. J Biol Chem. 2006 Feb 10; 281(6):3425-31. PMID: 16332682.
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    32. Addy NA, Pocivavsek A, Levin ED. Reversal of clozapine effects on working memory in rats with fimbria-fornix lesions. Neuropsychopharmacology. 2005 Jun; 30(6):1121-7. PMID: 15688087.
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