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David John Jollow

Title
InstitutionMedical University of South Carolina
DepartmentCell and Molecular Pharmacology and Experimental Therapeutics
AddressP.O. Box MSC 505
326A
173 Ashley Ave.
Phone843-792-2509
Fax843-792-2475
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Jollow DJ, Bruckner JV, McMillan DC, Fisher JW, Hoel DG, Mohr LC. Trichloroethylene risk assessment: a review and commentary. Crit Rev Toxicol. 2009; 39(9):782-97. PMID: 19852561.
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    2. Bronley-DeLancey A, McMillan DC, McMillan JM, Jollow DJ, Mohr LC, Hoel DG. Application of cryopreserved human hepatocytes in trichloroethylene risk assessment: relative disposition of chloral hydrate to trichloroacetate and trichloroethanol. Environ Health Perspect. 2006 Aug; 114(8):1237-42. PMID: 16882532.
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    3. McMillan DC, Powell CL, Bowman ZS, Morrow JD, Jollow DJ. Lipids versus proteins as major targets of pro-oxidant, direct-acting hemolytic agents. Toxicol Sci. 2005 Nov; 88(1):274-83. PMID: 16107547.
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    4. Bowman ZS, Jollow DJ, McMillan DC. Primaquine-induced hemolytic anemia: role of splenic macrophages in the fate of 5-hydroxyprimaquine-treated rat erythrocytes. J Pharmacol Exp Ther. 2005 Dec; 315(3):980-6. PMID: 16099929.
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    5. Bowman ZS, Morrow JD, Jollow DJ, McMillan DC. Primaquine-induced hemolytic anemia: role of membrane lipid peroxidation and cytoskeletal protein alterations in the hemotoxicity of 5-hydroxyprimaquine. J Pharmacol Exp Ther. 2005 Aug; 314(2):838-45. PMID: 15840764.
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    6. McMillan DC, Sarvate SD, Oatis JE, Jollow DJ. Role of oxidant stress in lawsone-induced hemolytic anemia. Toxicol Sci. 2004 Dec; 82(2):647-55. PMID: 15456924.
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    7. Walgren JL, Jollow DJ, McMillan JM. Induction of peroxisome proliferation in cultured hepatocytes by a series of halogenated acetates. Toxicology. 2004 May 03; 197(3):189-97. PMID: 15033542.
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    8. Bowman ZS, Oatis JE, Whelan JL, Jollow DJ, McMillan DC. Primaquine-induced hemolytic anemia: susceptibility of normal versus glutathione-depleted rat erythrocytes to 5-hydroxyprimaquine. J Pharmacol Exp Ther. 2004 Apr; 309(1):79-85. PMID: 14724225.
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    9. Jollow DJ. Highlights of International meeting on Alternative Methods of Carcinogenicity Testing, Leesburg, VA, November 1-3, 2000, Sponsored by the Health and Environmental Sciences Institute. J Agromedicine. 2004; 9(2):427-9. PMID: 19785235.
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    10. Bolchoz LJ, Gelasco AK, Jollow DJ, McMillan DC. Primaquine-induced hemolytic anemia: formation of free radicals in rat erythrocytes exposed to 6-methoxy-8-hydroxylaminoquinoline. J Pharmacol Exp Ther. 2002 Dec; 303(3):1121-9. PMID: 12438535.
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    11. Bolchoz LJ, Morrow JD, Jollow DJ, McMillan DC. Primaquine-induced hemolytic anemia: effect of 6-methoxy-8-hydroxylaminoquinoline on rat erythrocyte sulfhydryl status, membrane lipids, cytoskeletal proteins, and morphology. J Pharmacol Exp Ther. 2002 Oct; 303(1):141-8. PMID: 12235244.
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    12. McMillan DC, Bolchoz LJ, Jollow DJ. Favism: effect of divicine on rat erythrocyte sulfhydryl status, hexose monophosphate shunt activity, morphology, and membrane skeletal proteins. Toxicol Sci. 2001 Aug; 62(2):353-9. PMID: 11452148.
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    13. Bolchoz LJ, Budinsky RA, McMillan DC, Jollow DJ. Primaquine-induced hemolytic anemia: formation and hemotoxicity of the arylhydroxylamine metabolite 6-methoxy-8-hydroxylaminoquinoline. J Pharmacol Exp Ther. 2001 May; 297(2):509-15. PMID: 11303037.
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    14. Jollow DJ, McMillan DC. Oxidative stress, glucose-6-phosphate dehydrogenase and the red cell. Adv Exp Med Biol. 2001; 500:595-605. PMID: 11765001.
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    15. McMillan DC, Jollow DJ. Favism: divicine hemotoxicity in the rat. Toxicol Sci. 1999 Oct; 51(2):310-6. PMID: 10543033.
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    16. McMillan DC, Jensen CB, Jollow DJ. Role of lipid peroxidation in dapsone-induced hemolytic anemia. J Pharmacol Exp Ther. 1998 Dec; 287(3):868-76. PMID: 9864266.
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    17. Bradshaw TP, McMillan DC, Crouch RK, Jollow DJ. Formation of free radicals and protein mixed disulfides in rat red cells exposed to dapsone hydroxylamine. Free Radic Biol Med. 1997; 22(7):1183-93. PMID: 9098092.
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    18. Newman WH, Zhang LM, McDonald MH, Jollow DJ, Castresana MR. Tolerance to nitroglycerin in vascular smooth muscle cells is not affected by the level of intracellular glutathione or L-cysteine. Anesth Analg. 1995 Dec; 81(6):1229-34. PMID: 7486109.
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    19. McMillan DC, Simson JV, Budinsky RA, Jollow DJ. Dapsone-induced hemolytic anemia: effect of dapsone hydroxylamine on sulfhydryl status, membrane skeletal proteins and morphology of human and rat erythrocytes. J Pharmacol Exp Ther. 1995 Jul; 274(1):540-7. PMID: 7616443.
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    20. McMillan JM, Jollow DJ. Macrophage enhancement of galactosamine hepatotoxicity using a rat hepatocyte culture system. Res Commun Mol Pathol Pharmacol. 1995 Jun; 88(3):327-38. PMID: 8564388.
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    21. Grossman S, Budinsky R, Jollow D. Dapsone-induced hemolytic anemia: role of glucose-6-phosphate dehydrogenase in the hemolytic response of rat erythrocytes to N-hydroxydapsone. J Pharmacol Exp Ther. 1995 May; 273(2):870-7. PMID: 7752092.
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    22. Laskin DL, Gardner CR, Price VF, Jollow DJ. Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen. Hepatology. 1995 Apr; 21(4):1045-50. PMID: 7705777.
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    23. Bradshaw TP, McMillan DC, Crouch RK, Jollow DJ. Identification of free radicals produced in rat erythrocytes exposed to hemolytic concentrations of phenylhydroxylamine. Free Radic Biol Med. 1995 Feb; 18(2):279-85. PMID: 7744312.
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    24. Jollow DJ, Bradshaw TP, McMillan DC. Dapsone-induced hemolytic anemia. Drug Metab Rev. 1995; 27(1-2):107-24. PMID: 7641572.
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    25. McMillan DC, Schey KL, Meier GP, Jollow DJ. Chemical analysis and hemolytic activity of the fava bean aglycon divicine. Chem Res Toxicol. 1993 Jul-Aug; 6(4):439-44. PMID: 8374040.
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    26. Sanders TW, Reinhard MK, Jollow DJ, Hottendorf GH. Lack of in vivo evidence of a cytochrome P450 metabolite participating in aminoglycoside nephrotoxicity. Biochem Pharmacol. 1993 Feb 09; 45(3):780-2. PMID: 8442776.
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    27. Grossman SJ, Simson J, Jollow DJ. Dapsone-induced hemolytic anemia: effect of N-hydroxy dapsone on the sulfhydryl status and membrane proteins of rat erythrocytes. Toxicol Appl Pharmacol. 1992 Dec; 117(2):208-17. PMID: 1471153.
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    28. McMillan JM, Jollow DJ. Galactosamine hepatotoxicity: effect of galactosamine on glutathione resynthesis in rat primary hepatocyte cultures. Toxicol Appl Pharmacol. 1992 Aug; 115(2):234-40. PMID: 1641857.
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    29. Jensen CB, Jollow DJ. The role of N-hydroxyphenetidine in phenacetin-induced hemolytic anemia. Toxicol Appl Pharmacol. 1991 Oct; 111(1):1-12. PMID: 1949026.
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    30. McMillan DC, Bradshaw TP, Hinson JA, Jollow DJ. Role of metabolites in propanil-induced hemolytic anemia. Toxicol Appl Pharmacol. 1991 Aug; 110(1):70-8. PMID: 1871773.
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    31. Peters RH, Jollow DJ, Stuart RK. Role of glutathione in the in vitro synergism between 4-hydroperoxy-cyclophosphamide and cisplatin in leukemia cell lines. Cancer Res. 1991 May 15; 51(10):2536-41. PMID: 2021933.
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    32. Bradshaw TP, McMillan DC, Crouch RK, Jollow DJ. Arylamine-induced hemolytic anemia: electron spin resonance spectrometry studies. Adv Exp Med Biol. 1991; 283:253-5. PMID: 1648864.
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    33. McMillan DC, Bradshaw TP, McMillan JM, Hinson JA, Jollow DJ. Contribution of 3,4-dichlorophenylhydroxylamine in propanil-induced hemolytic anemia. Adv Exp Med Biol. 1991; 283:343-5. PMID: 2069006.
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    34. Roberts SA, Price VF, Jollow DJ. Acetaminophen structure-toxicity studies: in vivo covalent binding of a nonhepatotoxic analog, 3-hydroxyacetanilide. Toxicol Appl Pharmacol. 1990 Sep 01; 105(2):195-208. PMID: 2219115.
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    35. Peters RH, Ballard K, Oatis JE, Jollow DJ, Stuart RK. Cellular glutathione as a protective agent against 4-hydroperoxycyclophosphamide cytotoxicity in K-562 cells. Cancer Chemother Pharmacol. 1990; 26(6):397-402. PMID: 2225310.
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    36. Price VF, Jollow DJ. Effects of sulfur-amino acid-deficient diets on acetaminophen metabolism and hepatotoxicity in rats. Toxicol Appl Pharmacol. 1989 Nov; 101(2):356-69. PMID: 2815088.
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    37. Spaethe SM, Jollow DJ. Effect of cobalt protoporphyrin on hepatic drug-metabolizing enzymes. Specificity for cytochrome P-450. Biochem Pharmacol. 1989 Jun 15; 38(12):2027-38. PMID: 2742604.
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    38. Price VF, Jollow DJ. Effect of glucose and gluconeogenic substrates on fasting-induced suppression of acetaminophen glucuronidation in the rat. Biochem Pharmacol. 1989 Jan 15; 38(2):289-97. PMID: 2914012.
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    39. Price VF, Jollow DJ. Mechanism of decreased acetaminophen glucuronidation in the fasted rat. Biochem Pharmacol. 1988 Mar 15; 37(6):1067-75. PMID: 3128294.
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    40. Grossman SJ, Jollow DJ. Role of dapsone hydroxylamine in dapsone-induced hemolytic anemia. J Pharmacol Exp Ther. 1988 Jan; 244(1):118-25. PMID: 3335994.
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    41. Lee WM, Emerson DL, Young WO, Goldschmidt-Clermont PJ, Jollow DJ, Galbraith RM. Diminished serum Gc (vitamin D-binding protein) levels and increased Gc:G-actin complexes in a hamster model of fulminant hepatic necrosis. Hepatology. 1987 Sep-Oct; 7(5):825-30. PMID: 3115882.
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    42. Harrison JH, Jollow DJ. Contribution of aniline metabolites to aniline-induced methemoglobinemia. Mol Pharmacol. 1987 Sep; 32(3):423-31. PMID: 3670278.
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    43. Young WO, Goldschmidt-Clermont PJ, Emerson DL, Lee WM, Jollow DJ, Galbraith RM. Correlation between extent of liver damage in fulminant hepatic necrosis and complexing of circulating group-specific component (vitamin D-binding protein). J Lab Clin Med. 1987 Jul; 110(1):83-90. PMID: 3598340.
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    44. Miller MG, Jollow DJ. Relationship between sulfotransferase activity and susceptibility to acetaminophen-induced liver necrosis in the hamster. Drug Metab Dispos. 1987 Mar-Apr; 15(2):143-50. PMID: 2882969.
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    45. Price VF, Miller MG, Jollow DJ. Mechanisms of fasting-induced potentiation of acetaminophen hepatotoxicity in the rat. Biochem Pharmacol. 1987 Feb 15; 36(4):427-33. PMID: 3827934.
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    46. Grossman SJ, Jollow DJ. Use of the NIH shift to determine the relative contribution of competing pathways of aniline metabolism in the rat. Drug Metab Dispos. 1986 Nov-Dec; 14(6):689-91. PMID: 2877827.
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    47. Harrison JH, Jollow DJ. Role of aniline metabolites in aniline-induced hemolytic anemia. J Pharmacol Exp Ther. 1986 Sep; 238(3):1045-54. PMID: 3746658.
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    48. Miller MG, Jollow DJ. Acetaminophen hepatotoxicity: studies on the mechanism of cysteamine protection. Toxicol Appl Pharmacol. 1986 Mar 30; 83(1):115-25. PMID: 3952741.
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    49. Miller MG, Price VF, Jollow DJ. Anomalous susceptibility of the fasted hamster to acetaminophen hepatotoxicity. Biochem Pharmacol. 1986 Mar 01; 35(5):817-25. PMID: 3754139.
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    50. Price VF, Jollow DJ. Strain differences in susceptibility of normal and diabetic rats to acetaminophen hepatotoxicity. Biochem Pharmacol. 1986 Feb 15; 35(4):687-95. PMID: 3081010.
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    51. Jollow DJ, Grossman SJ, Harrison JH. Hydroxylamines and hemolytic anemia. Adv Exp Med Biol. 1986; 197:573-82. PMID: 3766282.
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    52. Roberts SA, Price VF, Jollow DJ. The mechanisms of cobalt chloride-induced protection against acetaminophen hepatotoxicity. Drug Metab Dispos. 1986 Jan-Feb; 14(1):25-33. PMID: 2868861.
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    53. Jensen CB, Grossman SJ, Jollow DJ. Improved method for determination of cellular thiols, disulfides and protein mixed disulfides using HPLC with electrochemical detection. Adv Exp Med Biol. 1986; 197:407-13. PMID: 3766271.
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    54. Price VF, Schulte JM, Spaethe SM, Jollow DJ. Mechanism of fasting-induced suppression of acetaminophen glucuronidation in the rat. Adv Exp Med Biol. 1986; 197:697-706. PMID: 2945409.
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    55. Price VF, Jollow DJ. Role of UDPGA flux in acetaminophen clearance and hepatotoxicity. Xenobiotica. 1984 Jul; 14(7):553-9. PMID: 6438923.
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    56. Miller MG, Jollow DJ. Effect of L-ascorbic acid on acetaminophen-induced hepatotoxicity and covalent binding in hamsters. Evidence that in vitro covalent binding differs from that in vivo. Drug Metab Dispos. 1984 May-Jun; 12(3):271-9. PMID: 6145552.
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    57. Harrison JH, Jollow DJ. Rapid and sensitive method for the microassay of nitrosobenzene plus phenylhydroxylamine in blood. J Chromatogr. 1983 Oct 14; 277:173-82. PMID: 6643603.
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    58. Price VF, Jollow DJ. Mechanism of ketone-induced protection from acetaminophen hepatotoxicity in the rat. Drug Metab Dispos. 1983 Sep-Oct; 11(5):451-7. PMID: 6138230.
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    59. Chong KP, Burch RM, Black M, Maloney E, Jollow DJ, Halushka PV. Vasopressin stimulates thromboxane synthesis in isolated hamster hepatocytes: relation to hepatocyte calcium content. Prostaglandins. 1983 Sep; 26(3):397-408. PMID: 6419286.
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    60. Price VF, Jollow DJ. Increased resistance of diabetic rats to acetaminophen-induced hepatotoxicity. J Pharmacol Exp Ther. 1982 Mar; 220(3):504-13. PMID: 7062262.
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    61. Jollow DJ, Roberts S, Price V, Longacre S, Smith C. Pharmacokinetic considerations in toxicity testing. Drug Metab Rev. 1982; 13(6):983-1007. PMID: 6754320.
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    62. Jollow DJ, Roberts S, Price V, Smith C. Biochemical basis for dose response relationships in reactive metabolite toxicity. Adv Exp Med Biol. 1981; 136 Pt A:99-113. PMID: 7344497.
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    63. Gillette JR, Nelson SD, Mulder GJ, Jollow DJ, Mitchell JR, Pohl LR, Hinson JA. Formation of chemically reactive metabolites of phenacetin and acetaminophen. Adv Exp Med Biol. 1981; 136 Pt B:931-50. PMID: 6953755.
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    64. Jollow DJ. Glutathione thresholds in reactive metabolite toxicity. Arch Toxicol Suppl. 1980; 3:95-110. PMID: 6930953.
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    65. Sawyer PR, Cowart TD, Hurwitz GA, Halushka PV, Jollow DJ. Acetaminophen overdosage. J S C Med Assoc. 1977 Nov; 73(11):474-80. PMID: 270599.
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    66. Mitchell JR, Nelson WL, Potter WZ, Sasame HA, Jollow DJ. Metabolic activation of furosemide to a chemically reactive, hepatotoxic metabolite. J Pharmacol Exp Ther. 1976 Oct; 199(1):41-52. PMID: 978483.
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    67. Hinson JA, Mitchell JR, Jollow DJ. N-hydroxylation of p-chloroacetanilde in hamsters. Biochem Pharmacol. 1976 Mar 01; 25(5):599-601. PMID: 942495.
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    68. Thorgeirsson SS, Sasame HA, Mitchell JR, Jollow DJ, Potter WZ. Biochemical changes after hepatic injury from toxic doses of acetaminophen or furosemide. Pharmacology. 1976; 14(3):205-17. PMID: 183224.
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    69. Mitchell JR, Long MW, Thorgeirsson UP, Jollow DJ. Acetylation rates and monthly liver function tests during one year of isoniazid preventive therapy. Chest. 1975 Aug; 68(2):181-90. PMID: 1080096.
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    70. Mitchell JR, Potter WZ, Hinson JA, Jollow DJ. Hepatic necrosis caused by furosemide. Nature. 1974 Oct 11; 251(5475):508-11. PMID: 4424638.
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    71. Mitchell JR, Thorgeirsson SS, Potter WZ, Jollow DJ, Keiser H. Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy. Clin Pharmacol Ther. 1974 Oct; 16(4):676-84. PMID: 4417718.
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    72. Davis DC, Potter WZ, Jollow DJ, Mitchell JR. Species differences in hepatic glutathione depletion, covalent binding and hepatic necrosis after acetaminophen. Life Sci. 1974 Jun 01; 14(11):2099-109. PMID: 4847802.
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    73. Jollow DJ, Mitchell JR, Zampaglione N, Gillette JR. Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite. Pharmacology. 1974; 11(3):151-69. PMID: 4831804.
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    74. Jollow DJ, Thorgeirsson SS, Potter WZ, Hashimoto M, Mitchell JR. Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen. Pharmacology. 1974; 12(4-5):251-71. PMID: 4449889.
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    75. Potter WZ, Thorgeirsson SS, Jollow DJ, Mitchell JR. Acetaminophen-induced hepatic necrosis. V. Correlation of hepatic necrosis, covalent binding and glutathione depletion in hamsters. Pharmacology. 1974; 12(3):129-43. PMID: 4445191.
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    76. Potter WZ, Davis DC, Mitchell JR, Jollow DJ, Gillette JR, Brodie BB. Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro. J Pharmacol Exp Ther. 1973 Oct; 187(1):203-10. PMID: 4147720.
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    77. Zampaglione N, Jollow DJ, Mitchell JR, Stripp B, Hamrick M, Gillette JR. Role of detoxifying enzymes in bromobenzene-induced liver necrosis. J Pharmacol Exp Ther. 1973 Oct; 187(1):218-27. PMID: 4746330.
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    78. Mitchell JR, Jollow DJ, Potter WZ, Gillette JR, Brodie BB. Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione. J Pharmacol Exp Ther. 1973 Oct; 187(1):211-7. PMID: 4746329.
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    79. Jollow DJ, Mitchell JR, Potter WZ, Davis DC, Gillette JR, Brodie BB. Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo. J Pharmacol Exp Ther. 1973 Oct; 187(1):195-202. PMID: 4746327.
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    80. Mitchell JR, Jollow DJ, Potter WZ, Davis DC, Gillette JR, Brodie BB. Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism. J Pharmacol Exp Ther. 1973 Oct; 187(1):185-94. PMID: 4746326.
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    81. Thorgeirsson SS, Jollow DJ, Sasame HA, Green I, Mitchell JR. The role of cytochrome P-450 in N-hydroxylation of 2-acetylaminofluorene. Mol Pharmacol. 1973 May; 9(3):398-404. PMID: 4122821.
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    82. Mitchell JR, Jollow DJ, Gillette JR, Brodie BB. Drug metabolism as a cause of drug toxicity. Drug Metab Dispos. 1973 Jan-Feb; 1(1):418-23. PMID: 4149413.
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    83. Jollow DJ. Proceedings: Mechanisms of drug absorption and of drug solution. Rev Can Biol. 1973; 32:Suppl:7-19. PMID: 4777606.
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    84. Jollow DJ, Brodie BB. Mechanisms of drug absorption and of drug solution. Pharmacology. 1972; 8(1):21-32. PMID: 4644653.
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    85. Lukins HB, Jollow D, Wallace PG, Linnane AW. The biogenesis of mitochondria. 7. The effects of glucose repression on the lipid and enzyme composition of mitochondria from yeast. Aust J Exp Biol Med Sci. 1968 Dec; 46(6):651-65. PMID: 5729723.
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    86. Jollow D, Kellerman GM, Linnane AW. The biogenesis of mitochondria. 3. The lipid composition of aerobically and anaerobically grown Saccharomyces cerevisiae as related to the membrane systems of the cells. J Cell Biol. 1968 May; 37(2):221-30. PMID: 4297785.
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    87. Proudlock JW, Wheeldon LW, Jollow DJ, Linnane AW. Role of sterols in Saccharomyces cerevisiae. Biochim Biophys Acta. 1968 Mar 04; 152(2):434-7. PMID: 5639274.
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    88. KELLERMAN GM, JOLLOW DJ. CONVERSION OF STEARIC ACID INTO OLEIC ACID IN ADIPOSE TISSUE. Biochim Biophys Acta. 1964 Aug 05; 84:478-80. PMID: 14230826.
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