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Christina L Grek

Title
InstitutionMedical University of South Carolina
DepartmentCell and Molecular Pharmacology and Experimental Therapeutics
AddressCR 304
173 Ashley Ave.
Phone843-792-2112
Fax843-792-8801
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hansen RS, Thuesen KKH, Bregnhøj A, Moldovan LI, Kristensen LS, Grek CL, Ghatnekar GS, Iversen L, Johansen C. The HSP90 inhibitor RGRN-305 exhibits strong immunomodulatory effects in human keratinocytes. Exp Dermatol. 2021 Feb 14. PMID: 33583094.
      View in: PubMed
    2. Roberts R, Smyth JW, Will J, Roberts P, Grek CL, Ghatnekar GS, Sheng Z, Gourdie RG, Lamouille S, Foster EJ. Development of PLGA nanoparticles for sustained release of a connexin43 mimetic peptide to target glioblastoma cells. Mater Sci Eng C Mater Biol Appl. 2020 Mar; 108:110191. PMID: 31923988.
      View in: PubMed
    3. Montgomery J, Ghatnekar GS, Grek CL, Moyer KE, Gourdie RG. Connexin 43-Based Therapeutics for Dermal Wound Healing. Int J Mol Sci. 2018 06 15; 19(6). PMID: 29914066.
      View in: PubMed
    4. Grek CL, Sheng Z, Naus CC, Sin WC, Gourdie RG, Ghatnekar GG. Novel approach to temozolomide resistance in malignant glioma: connexin43-directed therapeutics. Curr Opin Pharmacol. 2018 08; 41:79-88. PMID: 29803991.
      View in: PubMed
    5. Cox AA, Sagot Y, Hedou G, Grek C, Wilkes T, Vinik AI, Ghatnekar G. Low-Dose Pulsatile Interleukin-6 As a Treatment Option for Diabetic Peripheral Neuropathy. Front Endocrinol (Lausanne). 2017; 8:89. PMID: 28512447.
      View in: PubMed
    6. Obert E, Strauss R, Brandon C, Grek C, Ghatnekar G, Gourdie R, Rohrer B. Targeting the tight junction protein, zonula occludens-1, with the connexin43 mimetic peptide, aCT1, reduces VEGF-dependent RPE pathophysiology. J Mol Med (Berl). 2017 05; 95(5):535-552. PMID: 28132078.
      View in: PubMed
    7. Grek CL, Montgomery J, Sharma M, Ravi A, Rajkumar JS, Moyer KE, Gourdie RG, Ghatnekar GS. A Multicenter Randomized Controlled Trial Evaluating a Cx43-Mimetic Peptide in Cutaneous Scarring. J Invest Dermatol. 2017 03; 137(3):620-630. PMID: 27856288.
      View in: PubMed
    8. Grek CL, Rhett JM, Bruce JS, Ghatnekar GS, Yeh ES. Connexin 43, breast cancer tumor suppressor: Missed connections? Cancer Lett. 2016 Apr 28; 374(1):117-126. PMID: 26884256.
      View in: PubMed
    9. Abt MA, Grek CL, Ghatnekar GS, Yeh ES. Evaluation of Lung Metastasis in Mouse Mammary Tumor Models by Quantitative Real-time PCR. J Vis Exp. 2016 Jan 29; (107):e53329. PMID: 26862835.
      View in: PubMed
    10. Grek CL, Prasad GM, Viswanathan V, Armstrong DG, Gourdie RG, Ghatnekar GS. Topical administration of a connexin43-based peptide augments healing of chronic neuropathic diabetic foot ulcers: A multicenter, randomized trial. Wound Repair Regen. 2015 Mar-Apr; 23(2):203-12. PMID: 25703647.
      View in: PubMed
    11. Grek CL, Rhett JM, Bruce JS, Abt MA, Ghatnekar GS, Yeh ES. Targeting connexin 43 with a-connexin carboxyl-terminal (ACT1) peptide enhances the activity of the targeted inhibitors, tamoxifen and lapatinib, in breast cancer: clinical implication for ACT1. BMC Cancer. 2015 Apr 03; 15:296. PMID: 25881004.
      View in: PubMed
    12. Grek CL, Reyes L, Townsend DM, Tew KD. S-glutathionylation of buccal cell proteins as biomarkers of exposure to hydrogen peroxide. BBA Clin. 2014 Dec; 2:31-9. PMID: 26673080.
      View in: PubMed
    13. Ghatnekar GS, Grek CL, Armstrong DG, Desai SC, Gourdie RG. The effect of a connexin43-based Peptide on the healing of chronic venous leg ulcers: a multicenter, randomized trial. J Invest Dermatol. 2015 Jan; 135(1):289-298. PMID: 25072595.
      View in: PubMed
    14. Grek CL, Rhett JM, Ghatnekar GS. Cardiac to cancer: connecting connexins to clinical opportunity. FEBS Lett. 2014 Apr 17; 588(8):1349-64. PMID: 24607540.
      View in: PubMed
    15. Zhang J, Grek C, Ye ZW, Manevich Y, Tew KD, Townsend DM. Pleiotropic functions of glutathione S-transferase P. Adv Cancer Res. 2014; 122:143-75. PMID: 24974181.
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    16. Grek CL, Zhang J, Manevich Y, Townsend DM, Tew KD. Causes and consequences of cysteine S-glutathionylation. J Biol Chem. 2013 Sep 13; 288(37):26497-504. PMID: 23861399.
      View in: PubMed
    17. Grek CL, Townsend DM, Uys JD, Manevich Y, Coker WJ, Pazoles CJ, Tew KD. S-glutathionylated serine proteinase inhibitors as plasma biomarkers in assessing response to redox-modulating drugs. Cancer Res. 2012 May 01; 72(9):2383-93. PMID: 22406622.
      View in: PubMed
    18. Tew KD, Manevich Y, Grek C, Xiong Y, Uys J, Townsend DM. The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer. Free Radic Biol Med. 2011 Jul 15; 51(2):299-313. PMID: 21558000.
      View in: PubMed
    19. Grek CL, Townsend DM, Tew KD. The impact of redox and thiol status on the bone marrow: Pharmacological intervention strategies. Pharmacol Ther. 2011 Feb; 129(2):172-84. PMID: 20951732.
      View in: PubMed
    20. Grek CL, Tew KD. Redox metabolism and malignancy. Curr Opin Pharmacol. 2010 Aug; 10(4):362-8. PMID: 20627682.
      View in: PubMed
    21. Grek CL, Newton DA, Spyropoulos DD, Baatz JE. Hypoxia up-regulates expression of hemoglobin in alveolar epithelial cells. Am J Respir Cell Mol Biol. 2011 Apr; 44(4):439-47. PMID: 20508070.
      View in: PubMed
    22. Grek CL, Newton DA, Qiu Y, Wen X, Spyropoulos DD, Baatz JE. Characterization of alveolar epithelial cells cultured in semipermeable hollow fibers. Exp Lung Res. 2009 Mar; 35(2):155-74. PMID: 19263283.
      View in: PubMed
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