Alessandra Metelli

Title
InstitutionMedical University of South Carolina
DepartmentMicro And Immuno - Research And PI
AddressP.O. Box MSC 955
HO603
Hollings Cancer Center - 86 Jonathan Lucas St.
Phone843-792-7522
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Metelli A, Wu BX, Riesenberg B, Guglietta S, Huck JD, Mills C, Li A, Rachidi S, Krieg C, Rubinstein MP, Gewirth DT, Sun S, Lilly MB, Wahlquist AH, Carbone DP, Yang Y, Liu B, Li Z. Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-ß. Sci Transl Med. 2020 01 08; 12(525). PMID: 31915300.
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    2. Salem M, Wallace C, Velegraki M, Li A, Ansa-Addo E, Metelli A, Kwon H, Riesenberg B, Wu B, Zhang Y, Guglietta S, Sun S, Liu B, Li Z. GARP Dampens Cancer Immunity by Sustaining Function and Accumulation of Regulatory T Cells in the Colon. Cancer Res. 2019 03 15; 79(6):1178-1190. PMID: 30674536.
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    3. Wallace CH, Wu BX, Salem M, Ansa-Addo EA, Metelli A, Sun S, Gilkeson G, Shlomchik MJ, Liu B, Li Z. B lymphocytes confer immune tolerance via cell surface GARP-TGF-ß complex. JCI Insight. 2018 04 05; 3(7). PMID: 29618665.
      Citations:    
    4. Metelli A, Salem M, Wallace CH, Wu BX, Li A, Li X, Li Z. Immunoregulatory functions and the therapeutic implications of GARP-TGF-ß in inflammation and cancer. J Hematol Oncol. 2018 02 20; 11(1):24. PMID: 29458436.
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    5. Rachidi S, Metelli A, Riesenberg B, Wu BX, Nelson MH, Wallace C, Paulos CM, Rubinstein MP, Garrett-Mayer E, Hennig M, Bearden DW, Yang Y, Liu B, Li Z. Platelets subvert T cell immunity against cancer via GARP-TGFß axis. Sci Immunol. 2017 May 05; 2(11). PMID: 28763790.
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    6. Metelli A, Wu BX, Fugle CW, Rachidi S, Sun S, Zhang Y, Wu J, Tomlinson S, Howe PH, Yang Y, Garrett-Mayer E, Liu B, Li Z. Surface Expression of TGFß Docking Receptor GARP Promotes Oncogenesis and Immune Tolerance in Breast Cancer. Cancer Res. 2016 12 15; 76(24):7106-7117. PMID: 27913437.
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    7. Ansa-Addo EA, Thaxton J, Hong F, Wu BX, Zhang Y, Fugle CW, Metelli A, Riesenberg B, Williams K, Gewirth DT, Chiosis G, Liu B, Li Z. Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94. Curr Top Med Chem. 2016; 16(25):2765-78. PMID: 27072698.
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    8. Ferradini N, Iannacone R, Capomaccio S, Metelli A, Armentano N, Semeraro L, Cellini F, Veronesi F, Rosellini D. Assessment of heat shock protein 70 induction by heat in alfalfa varieties and constitutive overexpression in transgenic plants. PLoS One. 2015; 10(5):e0126051. PMID: 25951604.
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    9. Zhang Y, Wu BX, Metelli A, Thaxton JE, Hong F, Rachidi S, Ansa-Addo E, Sun S, Vasu C, Yang Y, Liu B, Li Z. GP96 is a GARP chaperone and controls regulatory T cell functions. J Clin Invest. 2015 Feb; 125(2):859-69. PMID: 25607841.
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    10. Matmati N, Metelli A, Tripathi K, Yan S, Mohanty BK, Hannun YA. Identification of C18:1-phytoceramide as the candidate lipid mediator for hydroxyurea resistance in yeast. J Biol Chem. 2013 Jun 14; 288(24):17272-84. PMID: 23620586.
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    11. Zhou C, Han L, Hou C, Metelli A, Qi L, Tadege M, Mysore KS, Wang ZY. Developmental analysis of a Medicago truncatula smooth leaf margin1 mutant reveals context-dependent effects on compound leaf development. Plant Cell. 2011 Jun; 23(6):2106-24. PMID: 21693694.
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