Pieter B. Burger

Title
InstitutionMedical University of South Carolina
DepartmentSCCP Drug Discovery and Biomedical Sciences - MUSC Campus
AddressP.O. Box MSC 139
DD402
Drug Discovery Building - 70 President St.
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Strong KL, Epplin MP, Ogden KK, Burger PB, Kaiser TM, Wilding TJ, Kusumoto H, Camp CR, Shaulsky G, Bhattacharya S, Perszyk RE, Menaldino DS, McDaniel MJ, Zhang J, Le P, Banke TG, Hansen KB, Huettner JE, Liotta DC, Traynelis SF. Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N-Methyl-d-aspartate Receptors. ACS Chem Neurosci. 2021 01 06; 12(1):79-98. PMID: 33326224.
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    2. Zhu Z, Yi F, Epplin MP, Liu D, Summer SL, Mizu R, Shaulsky G, XiangWei W, Tang W, Burger PB, Menaldino DS, Myers SJ, Liotta DC, Hansen KB, Yuan H, Traynelis SF. Negative allosteric modulation of GluN1/GluN3 NMDA receptors. Neuropharmacology. 2020 10 01; 176:108117. PMID: 32389749.
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    3. Pribut N, Kaiser TM, Wilson RJ, Jecs E, Dentmon ZW, Pelly SC, Sharma S, Bartsch PW, Burger PB, Hwang SS, Le T, Sourimant J, Yoon JJ, Plemper RK, Liotta DC. Accelerated Discovery of Potent Fusion Inhibitors for Respiratory Syncytial Virus. ACS Infect Dis. 2020 05 08; 6(5):922-929. PMID: 32275393.
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    4. McDaniel MJ, Ogden KK, Kell SA, Burger PB, Liotta DC, Traynelis SF. NMDA receptor channel gating control by the pre-M1 helix. J Gen Physiol. 2020 04 06; 152(4). PMID: 32221541.
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    5. Cleaves HJ, Butch C, Burger PB, Goodwin J, Meringer M. One Among Millions: The Chemical Space of Nucleic Acid-Like Molecules. J Chem Inf Model. 2019 10 28; 59(10):4266-4277. PMID: 31498614.
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    6. Kaiser TM, Burger PB. Error Tolerance of Machine Learning Algorithms across Contemporary Biological Targets. Molecules. 2019 Jun 04; 24(11). PMID: 31167452.
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    7. Holshouser S, Dunworth M, Murray-Stewart T, Peterson YK, Burger P, Kirkpatrick J, Chen HH, Casero RA, Woster PM. Dual inhibitors of LSD1 and spermine oxidase. Medchemcomm. 2019 May 01; 10(5):778-790. PMID: 31191868.
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    8. Zambrano JN, Williams CJ, Williams CB, Hedgepeth L, Burger P, Dilday T, Eblen ST, Armeson K, Hill EG, Yeh ES. Staurosporine, an inhibitor of hormonally up-regulated neu-associated kinase. Oncotarget. 2018 Nov 13; 9(89):35962-35973. PMID: 30542510.
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    9. Kaiser TM, Burger PB, Butch CJ, Pelly SC, Liotta DC. A Machine Learning Approach for Predicting HIV Reverse Transcriptase Mutation Susceptibility of Biologically Active Compounds. J Chem Inf Model. 2018 08 27; 58(8):1544-1552. PMID: 29953819.
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    10. Kaiser TM, Kell SA, Kusumoto H, Shaulsky G, Bhattacharya S, Epplin MP, Strong KL, Miller EJ, Cox BD, Menaldino DS, Liotta DC, Traynelis SF, Burger PB. The Bioactive Protein-Ligand Conformation of GluN2C-Selective Positive Allosteric Modulators Bound to the NMDA Receptor. Mol Pharmacol. 2018 02; 93(2):141-156. PMID: 29242355.
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    11. Strong KL, Epplin MP, Bacsa J, Butch CJ, Burger PB, Menaldino DS, Traynelis SF, Liotta DC. The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate Receptors. J Med Chem. 2017 07 13; 60(13):5556-5585. PMID: 28586221.
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    12. Chen W, Tankovic A, Burger PB, Kusumoto H, Traynelis SF, Yuan H. Functional Evaluation of a De Novo GRIN2A Mutation Identified in a Patient with Profound Global Developmental Delay and Refractory Epilepsy. Mol Pharmacol. 2017 04; 91(4):317-330. PMID: 28126851.
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    13. Swanger SA, Chen W, Wells G, Burger PB, Tankovic A, Bhattacharya S, Strong KL, Hu C, Kusumoto H, Zhang J, Adams DR, Millichap JJ, Petrovski S, Traynelis SF, Yuan H. Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains. Am J Hum Genet. 2016 Dec 01; 99(6):1261-1280. PMID: 27839871.
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    14. Burger PB, Williams M, Sprenger J, Reeksting SB, Botha M, Müller IB, Joubert F, Birkholtz LM, Louw AI. A novel inhibitor of Plasmodium falciparum spermidine synthase: a twist in the tail. Malar J. 2015 Feb 05; 14:54. PMID: 25651815.
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    15. Khatri A, Burger PB, Swanger SA, Hansen KB, Zimmerman S, Karakas E, Liotta DC, Furukawa H, Snyder JP, Traynelis SF. Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator. Mol Pharmacol. 2014 Nov; 86(5):548-60. PMID: 25205677.
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    16. le Roux D, Burger PB, Niemand J, Grobler A, Urbán P, Fernàndez-Busquets X, Barker RH, Serrano AE, I Louw A, Birkholtz LM. Novel S-adenosyl-L-methionine decarboxylase inhibitors as potent antiproliferative agents against intraerythrocytic Plasmodium falciparum parasites. Int J Parasitol Drugs Drug Resist. 2014 Apr; 4(1):28-36. PMID: 24596666.
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    17. Mpangase PT, Szolkiewicz MJ, le Grange M, Smit JH, Burger PB, Joubert F. Discovery-2: an interactive resource for the rational selection and comparison of putative drug target proteins in malaria. Malar J. 2013 Mar 28; 12:116. PMID: 23537208.
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    18. Reeksting SB, Müller IB, Burger PB, Burgos ES, Salmon L, Louw AI, Birkholtz LM, Wrenger C. Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum. Biochem J. 2013 Jan 01; 449(1):175-87. PMID: 23039077.
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    19. Burger PB, Yuan H, Karakas E, Geballe M, Furukawa H, Liotta DC, Snyder JP, Traynelis SF. Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators. Mol Pharmacol. 2012 Aug; 82(2):344-59. PMID: 22596351.
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    20. Acker TM, Yuan H, Hansen KB, Vance KM, Ogden KK, Jensen HS, Burger PB, Mullasseril P, Snyder JP, Liotta DC, Traynelis SF. Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators. Mol Pharmacol. 2011 Nov; 80(5):782-95. PMID: 21807990.
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    21. Dravid SM, Burger PB, Prakash A, Geballe MT, Yadav R, Le P, Vellano K, Snyder JP, Traynelis SF. Structural determinants of D-cycloserine efficacy at the NR1/NR2C NMDA receptors. J Neurosci. 2010 Feb 17; 30(7):2741-54. PMID: 20164358.
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    22. Burger PB, Birkholtz LM, Joubert F, Haider N, Walter RD, Louw AI. Structural and mechanistic insights into the action of Plasmodium falciparum spermidine synthase. Bioorg Med Chem. 2007 Feb 15; 15(4):1628-37. PMID: 17196392.
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