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Ehtesham Arif

Title
InstitutionMedical University of South Carolina
DepartmentNephrology
AddressP.O. Box MSC 629
Drug Discovery Building, 5th Floor
Drug Discovery Building - 70 President St.
Phone843-876-2369
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hammad SM, Twal WO, Arif E, Semler AJ, Klein RL, Nihalani D. Transcriptomics Reveal Altered Metabolic and Signaling Pathways in Podocytes Exposed to C16 Ceramide-Enriched Lipoproteins. Genes (Basel). 2020 Feb 07; 11(2). PMID: 32045989.
      View in: PubMed
    2. Solanki AK, Srivastava P, Rahman B, Lipschutz JH, Nihalani D, Arif E. The Use of High-Throughput Transcriptomics to Identify Pathways with Therapeutic Significance in Podocytes. Int J Mol Sci. 2019 Dec 31; 21(1). PMID: 31906131.
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    3. Lombardi AA, Gibb AA, Arif E, Kolmetzky DW, Tomar D, Luongo TS, Jadiya P, Murray EK, Lorkiewicz PK, Hajnóczky G, Murphy E, Arany ZP, Kelly DP, Margulies KB, Hill BG, Elrod JW. Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation. Nat Commun. 2019 10 04; 10(1):4509. PMID: 31586055.
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    4. Solanki AK, Widmeier E, Arif E, Sharma S, Daga A, Srivastava P, Kwon SH, Hugo H, Nakayama M, Mann N, Majmundar AJ, Tan W, Gee HY, Sadowski CE, Rinat C, Becker-Cohen R, Bergmann C, Rosen S, Somers M, Shril S, Huber TB, Mane S, Hildebrandt F, Nihalani D. Mutations in KIRREL1, a slit diaphragm component, cause steroid-resistant nephrotic syndrome. Kidney Int. 2019 Oct; 96(4):883-889. PMID: 31472902.
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    5. Nihalani D, Solanki AK, Arif E, Srivastava P, Rahman B, Zuo X, Dang Y, Fogelgren B, Fermin D, Gillies CE, Sampson MG, Lipschutz JH. Disruption of the exocyst induces podocyte loss and dysfunction. J Biol Chem. 2019 06 28; 294(26):10104-10119. PMID: 31073028.
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    6. Arif E, Solanki AK, Srivastava P, Rahman B, Fitzgibbon WR, Deng P, Budisavljevic MN, Baicu CF, Zile MR, Megyesi J, Janech MG, Kwon SH, Collier J, Schnellmann RG, Nihalani D. Mitochondrial biogenesis induced by the ß2-adrenergic receptor agonist formoterol accelerates podocyte recovery from glomerular injury. Kidney Int. 2019 Sep; 96(3):656-673. PMID: 31262488.
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    7. Arif E, Nihalani D. Beta2-adrenergic receptor in kidney biology: A current prospective. Nephrology (Carlton). 2019 May; 24(5):497-503. PMID: 30848004.
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    8. Arif E, Solanki AK, Srivastava P, Rahman B, Tash BR, Holzman LB, Janech MG, Martin R, Knölker HJ, Fitzgibbon WR, Deng P, Budisavljevic MN, Syn WK, Wang C, Lipschutz JH, Kwon SH, Nihalani D. The motor protein Myo1c regulates transforming growth factor-ß-signaling and fibrosis in podocytes. Kidney Int. 2019 Jul; 96(1):139-158. PMID: 31097328.
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    9. Srivastava P, Solanki AK, Arif E, Wolf BJ, Janech MG, Budisavljevic MN, Kwon SH, Nihalani D. Development of a novel cell-based assay to diagnose recurrent focal segmental glomerulosclerosis patients. Kidney Int. 2019 03; 95(3):708-716. PMID: 30709661.
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    10. Solanki AK, Arif E, Morinelli T, Wilson RC, Hardiman G, Deng P, Arthur JM, Velez JC, Nihalani D, Janech MG, Budisavljevic MN. A Novel CLCN5 Mutation Associated With Focal Segmental Glomerulosclerosis and Podocyte Injury. Kidney Int Rep. 2018 Nov; 3(6):1443-1453. PMID: 30426109.
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    11. Lee HW, Arif E, Altintas MM, Quick K, Maheshwari S, Plezia A, Mahmood A, Reiser J, Nihalani D, Gupta V. High-content screening assay-based discovery of paullones as novel podocyte-protective agents. Am J Physiol Renal Physiol. 2018 02 01; 314(2):F280-F292. PMID: 29046299.
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    12. Sagar A, Arif E, Solanki AK, Srivastava P, Janech MG, Kim SH, Lipschutz JH, Kwon SH, Nihalani D. Targeting Neph1 and ZO-1 protein-protein interaction in podocytes prevents podocyte injury and preserves glomerular filtration function. Sci Rep. 2017 09 21; 7(1):12047. PMID: 28935902.
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    13. Velez JCQ, Arif E, Rodgers J, Hicks MP, Arthur JM, Nihalani D, Bruner ET, Budisavljevic MN, Atkinson C, Fitzgibbon WR, Janech MG. Deficiency of the Angiotensinase Aminopeptidase A Increases Susceptibility to Glomerular Injury. J Am Soc Nephrol. 2017 Jul; 28(7):2119-2132. PMID: 28202497.
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    14. Arif E, Sharma P, Solanki A, Mallik L, Rathore YS, Twal WO, Nath SK, Gandhi D, Holzman LB, Ostap EM, Nihalani D. Structural Analysis of the Myo1c and Neph1 Complex Provides Insight into the Intracellular Movement of Neph1. Mol Cell Biol. 2016 06 01; 36(11):1639-54. PMID: 27044863.
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    15. Arif E, Solanki AK, Nihalani D. Adriamycin susceptibility among C57BL/6 substrains. Kidney Int. 2016 Mar; 89(3):721-3. PMID: 26880466.
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    16. Arif E, Rathore YS, Kumari B, Ashish F, Wong HN, Holzman LB, Nihalani D. Slit diaphragm protein Neph1 and its signaling: a novel therapeutic target for protection of podocytes against glomerular injury. J Biol Chem. 2014 Apr 04; 289(14):9502-18. PMID: 24554715.
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    17. Arif E, Kumari B, Wagner MC, Zhou W, Holzman LB, Nihalani D. Myo1c is an unconventional myosin required for zebrafish glomerular development. Kidney Int. 2013 Dec; 84(6):1154-65. PMID: 23715127.
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    18. Arif E, Nihalani D. Glomerular Filtration Barrier Assembly: An insight. Postdoc J. 2013 Apr; 1(4):33-45. PMID: 27583259.
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    19. Mallik L, Arif E, Sharma P, Rathore YS, Wong HN, Holzman LB, Nihalani D. Solution structure analysis of cytoplasmic domain of podocyte protein Neph1 using small/wide angle x-ray scattering (SWAXS). J Biol Chem. 2012 Mar 16; 287(12):9441-53. PMID: 22262837.
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    20. Sohail M, Kumar R, Kaul A, Arif E, Kumar S, Adak T. Polymorphism in glutathione S-transferase P1 is associated with susceptibility to Plasmodium vivax malaria compared to P. falciparum and upregulates the GST level during malarial infection. Free Radic Biol Med. 2010 Dec 01; 49(11):1746-54. PMID: 20840864.
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    21. Abhishek K, Kumar R, Arif E, Patra PK, Choudhary SB, Sohail M. Induced expression of bone morphogenetic protein-6 and Smads signaling in human monocytes derived dendritic cells during sickle-cell pathology with orthopedic complications. Biochem Biophys Res Commun. 2010 Jun 11; 396(4):950-5. PMID: 20460105.
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    22. Vibhuti A, Arif E, Mishra A, Deepak D, Singh B, Rahman I, Mohammad G, Pasha MA. CYP1A1, CYP1A2 and CYBA gene polymorphisms associated with oxidative stress in COPD. Clin Chim Acta. 2010 Apr 02; 411(7-8):474-80. PMID: 20080081.
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    23. Kumar R, Nejatizadeh A, Arif E, Akhtar S, Gupta M, Tyagi S, Goyal AK, Jain SK, Qadar Pasha MA. Multi-locus interactions of vascular homeostasis genes in essential hypertension: a gender-based study. Clin Chim Acta. 2009 Jul; 405(1-2):87-93. PMID: 19379721.
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    24. Hanif K, Pavar MC, Arif E, Biswas P, Fahim M, Pasha MA, Pasha S. Effect of 3-thienylalanine-ornithine-proline, new sulfur-containing angiotensin-converting enzyme inhibitor on blood pressure and oxidative stress in spontaneously hypertensive rats. J Cardiovasc Pharmacol. 2009 Feb; 53(2):145-50. PMID: 19188834.
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    25. Wagner MC, Rhodes G, Wang E, Pruthi V, Arif E, Saleem MA, Wean SE, Garg P, Verma R, Holzman LB, Gattone V, Molitoris BA, Nihalani D. Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1. J Biol Chem. 2008 Dec 19; 283(51):35579-89. PMID: 18922801.
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    26. Arif E, Vibhuti A, Deepak D, Singh B, Siddiqui MS, Pasha MA. COX2 and p53 risk-alleles coexist in COPD. Clin Chim Acta. 2008 Nov; 397(1-2):48-50. PMID: 18692035.
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    27. Karar J, Dolt KS, Mishra MK, Arif E, Javed S, Pasha MA. Expression and functional activity of pro-oxidants and antioxidants in murine heart exposed to acute hypobaric hypoxia. FEBS Lett. 2007 Oct 02; 581(24):4577-82. PMID: 17825300.
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    28. Arif E, Ahsan A, Vibhuti A, Rajput C, Deepak D, Athar M, Singh B, Pasha MA. Endothelial nitric oxide synthase gene variants contribute to oxidative stress in COPD. Biochem Biophys Res Commun. 2007 Sep 14; 361(1):182-8. PMID: 17658478.
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    29. Vibhuti A, Arif E, Deepak D, Singh B, Qadar Pasha MA. Correlation of oxidative status with BMI and lung function in COPD. Clin Biochem. 2007 Sep; 40(13-14):958-63. PMID: 17631288.
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    30. Vibhuti A, Arif E, Deepak D, Singh B, Qadar Pasha MA. Genetic polymorphisms of GSTP1 and mEPHX correlate with oxidative stress markers and lung function in COPD. Biochem Biophys Res Commun. 2007 Jul 20; 359(1):136-42. PMID: 17532303.
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    31. Arif E, Vibhuti A, Alam P, Deepak D, Singh B, Athar M, Pasha MA. Association of CYP2E1 and NAT2 gene polymorphisms with chronic obstructive pulmonary disease. Clin Chim Acta. 2007 Jul; 382(1-2):37-42. PMID: 17442289.
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    32. Rajput C, Arif E, Vibhuti A, Stobdan T, Khan AP, Norboo T, Afrin F, Qadar Pasha MA. Predominance of interaction among wild-type alleles of CYP11B2 in Himalayan natives associates with high-altitude adaptation. Biochem Biophys Res Commun. 2006 Sep 22; 348(2):735-40. PMID: 16893516.
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