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Peggi Melissa Angel

Title
InstitutionMedical University of South Carolina
DepartmentCell and Molecular Pharmacology and Experimental Therapeutics
AddressP.O. Box MSC 509
CRI315
Children's Research Inst. - 173 Ashley Ave.
Phone843-792-8410
Fax843-792-2475
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Clift CL, Su YR, Bichell D, Jensen Smith HC, Bethard JR, Norris-Caneda K, Comte-Walters S, Ball LE, Hollingsworth MA, Mehta AS, Drake RR, Angel PM. Collagen fiber regulation in human pediatric aortic valve development and disease. Sci Rep. 2021 May 07; 11(1):9751. PMID: 33963260.
      View in: PubMed
    2. Blaschke CRK, McDowell CT, Black AP, Mehta AS, Angel PM, Drake RR. Glycan Imaging Mass Spectrometry: Progress in Developing Clinical Diagnostic Assays for Tissues, Biofluids, and Cells. Clin Lab Med. 2021 Jun; 41(2):247-266. PMID: 34020762.
      View in: PubMed
    3. Angel PM. On the Cutting Edge of Translational Research. Clin Chem. 2021 Mar 31; 67(4):583-584. PMID: 33230521.
      View in: PubMed
    4. Angel PM, Drake RR, Park Y, Clift CL, West C, Berkhiser S, Hardiman G, Mehta AS, Bichell DP, Su YR. Spatial N-glycomics of the human aortic valve in development and pediatric endstage congenital aortic valve stenosis. J Mol Cell Cardiol. 2021 05; 154:6-20. PMID: 33516683.
      View in: PubMed
    5. Sundararaj K, Rodgers J, Angel P, Wolf B, Nowling TK. The role of neuraminidase in TLR4-MAPK signalling and the release of cytokines by lupus serum-stimulated mesangial cells. Immunology. 2021 Apr; 162(4):418-433. PMID: 33314123.
      View in: PubMed
    6. West CA, Lu X, Grimsley G, Norris-Caneda K, Mehta AS, Angel PM, Drake RR. Optimization of Multiple Glycosidase and Chemical Stabilization Strategies for N-Glycan Isomer Detection by Mass Spectrometry Imaging in Formalin-Fixed, Paraffin-Embedded Tissues. Methods Mol Biol. 2021; 2271:303-316. PMID: 33908016.
      View in: PubMed
    7. Angel PM, Mehta AS, Drake RR. Array-Based N-Glycan Profiling of Cells in Culture. Methods Mol Biol. 2021; 2271:331-342. PMID: 33908018.
      View in: PubMed
    8. McDowell CT, Klamer Z, Hall J, West CA, Wisniewski L, Powers TW, Angel PM, Mehta AS, Lewin DN, Haab BB, Drake RR. Imaging Mass Spectrometry and Lectin Analysis of N-Linked Glycans in Carbohydrate Antigen-Defined Pancreatic Cancer Tissues. Mol Cell Proteomics. 2020 Dec 08; 20:100012. PMID: 33581409.
      View in: PubMed
    9. Clift CL, Drake RR, Mehta A, Angel PM. Multiplexed imaging mass spectrometry of the extracellular matrix using serial enzyme digests from formalin-fixed paraffin-embedded tissue sections. Anal Bioanal Chem. 2021 Apr; 413(10):2709-2719. PMID: 33206215.
      View in: PubMed
    10. Blaschke CRK, Black AP, Mehta AS, Angel PM, Drake RR. Rapid N-Glycan Profiling of Serum and Plasma by a Novel Slide-Based Imaging Mass Spectrometry Workflow. J Am Soc Mass Spectrom. 2020 Dec 02; 31(12):2511-2520. PMID: 32809822.
      View in: PubMed
    11. Angel PM, Spruill L, Jefferson M, Bethard JR, Ball LE, Hughes-Halbert C, Drake RR. Zonal regulation of collagen-type proteins and posttranslational modifications in prostatic benign and cancer tissues by imaging mass spectrometry. Prostate. 2020 09; 80(13):1071-1086. PMID: 32687633.
      View in: PubMed
    12. Holmes DT, Romney MG, Angel P, DeMarco ML. Proteomic applications in pathology and laboratory medicine: Present state and future prospects. Clin Biochem. 2020 Aug; 82:12-20. PMID: 32442429.
      View in: PubMed
    13. Angel PM, Bruner E, Bethard J, Clift CL, Ball L, Drake RR, Feghali-Bostwick C. Extracellular matrix alterations in low-grade lung adenocarcinoma compared with normal lung tissue by imaging mass spectrometry. J Mass Spectrom. 2020 Apr; 55(4):e4450. PMID: 31654589.
      View in: PubMed
    14. Drake RR, McDowell C, West C, David F, Powers TW, Nowling T, Bruner E, Mehta AS, Angel PM, Marlow LA, Tun HW, Copland JA. Defining the human kidney N-glycome in normal and cancer tissues using MALDI imaging mass spectrometry. J Mass Spectrom. 2020 Apr; 55(4):e4490. PMID: 31860772.
      View in: PubMed
    15. Black AP, Angel PM, Drake RR, Mehta AS. Antibody Panel Based N-Glycan Imaging for N-Glycoprotein Biomarker Discovery. Curr Protoc Protein Sci. 2019 12; 98(1):e99. PMID: 31721442.
      View in: PubMed
    16. Pati S, Angel P, Drake RR, Wagner JJ, Cummings BS. Lipidomic changes in the rat hippocampus following cocaine conditioning, extinction, and reinstatement of drug-seeking. Brain Behav. 2019 12; 9(12):e01451. PMID: 31701674.
      View in: PubMed
    17. Angel PM, Saunders J, Clift CL, White-Gilbertson S, Voelkel-Johnson C, Yeh E, Mehta A, Drake RR. A Rapid Array-Based Approach to N-Glycan Profiling of Cultured Cells. J Proteome Res. 2019 10 04; 18(10):3630-3639. PMID: 31535553.
      View in: PubMed
    18. Drake RR, Angel PM, Wu J, Pachynski RK, Ippolito JE. How else can we approach prostate cancer biomarker discovery? Expert Rev Mol Diagn. 2020 02; 20(2):123-125. PMID: 31498690.
      View in: PubMed
    19. Black AP, Liang H, West CA, Wang M, Herrera HP, Haab BB, Angel PM, Drake RR, Mehta AS. A Novel Mass Spectrometry Platform for Multiplexed N-Glycoprotein Biomarker Discovery from Patient Biofluids by Antibody Panel Based N-Glycan Imaging. Anal Chem. 2019 07 02; 91(13):8429-8435. PMID: 31177770.
      View in: PubMed
    20. Herrera H, Dilday T, Uber A, Scott D, Zambrano JN, Wang M, Angel PM, Mehta AS, Drake RR, Hill EG, Yeh ES. Core-Fucosylated Tetra-Antennary N-Glycan Containing A Single N-Acetyllactosamine Branch Is Associated with Poor Survival Outcome in Breast Cancer. Int J Mol Sci. 2019 May 23; 20(10). PMID: 31126011.
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    21. Yang L, Kraemer M, Fang XF, Angel PM, Drake RR, Morris AJ, Smyth SS. LPA receptor 4 deficiency attenuates experimental atherosclerosis. J Lipid Res. 2019 05; 60(5):972-980. PMID: 30796085.
      View in: PubMed
    22. Angel PM, Schwamborn K, Comte-Walters S, Clift CL, Ball LE, Mehta AS, Drake RR. Extracellular Matrix Imaging of Breast Tissue Pathologies by MALDI-Imaging Mass Spectrometry. Proteomics Clin Appl. 2019 01; 13(1):e1700152. PMID: 30251340.
      View in: PubMed
    23. West CA, Wang M, Herrera H, Liang H, Black A, Angel PM, Drake RR, Mehta AS. N-Linked Glycan Branching and Fucosylation Are Increased Directly in Hcc Tissue As Determined through in Situ Glycan Imaging. J Proteome Res. 2018 10 05; 17(10):3454-3462. PMID: 30110170.
      View in: PubMed
    24. Angel PM, Norris-Caneda K, Drake RR. In Situ Imaging of Tryptic Peptides by MALDI Imaging Mass Spectrometry Using Fresh-Frozen or Formalin-Fixed, Paraffin-Embedded Tissue. Curr Protoc Protein Sci. 2018 11; 94(1):e65. PMID: 30114342.
      View in: PubMed
    25. Drake RR, Powers TW, Norris-Caneda K, Mehta AS, Angel PM. In Situ Imaging of N-Glycans by MALDI Imaging Mass Spectrometry of Fresh or Formalin-Fixed Paraffin-Embedded Tissue. Curr Protoc Protein Sci. 2018 11; 94(1):e68. PMID: 30074304.
      View in: PubMed
    26. Helke K, Angel P, Lu P, Garrett-Mayer E, Ogretmen B, Drake R, Voelkel-Johnson C. Ceramide Synthase 6 Deficiency Enhances Inflammation in the DSS model of Colitis. Sci Rep. 2018 01 26; 8(1):1627. PMID: 29374263.
      View in: PubMed
    27. Scott DA, Norris-Caneda K, Spruill L, Bruner E, Kono Y, Angel PM, Mehta AS, Drake RR. Specific N-Linked Glycosylation Patterns in Areas of Necrosis in Tumor Tissues. Int J Mass Spectrom. 2019 Mar; 437:69-76. PMID: 31031563.
      View in: PubMed
    28. Drake RR, West CA, Mehta AS, Angel PM. MALDI Mass Spectrometry Imaging of N-Linked Glycans in Tissues. Adv Exp Med Biol. 2018; 1104:59-76. PMID: 30484244.
      View in: PubMed
    29. Angel PM, Mehta A, Norris-Caneda K, Drake RR. MALDI Imaging Mass Spectrometry of N-glycans and Tryptic Peptides from the Same Formalin-Fixed, Paraffin-Embedded Tissue Section. Methods Mol Biol. 2018; 1788:225-241. PMID: 29058228.
      View in: PubMed
    30. Angel PM, Comte-Walters S, Ball LE, Talbot K, Mehta A, Brockbank KGM, Drake RR. Mapping Extracellular Matrix Proteins in Formalin-Fixed, Paraffin-Embedded Tissues by MALDI Imaging Mass Spectrometry. J Proteome Res. 2018 01 05; 17(1):635-646. PMID: 29161047.
      View in: PubMed
    31. Angel PM, Baldwin HS, Gottlieb Sen D, Su YR, Mayer JE, Bichell D, Drake RR. Advances in MALDI imaging mass spectrometry of proteins in cardiac tissue, including the heart valve. Biochim Biophys Acta Proteins Proteom. 2017 Jul; 1865(7):927-935. PMID: 28341601.
      View in: PubMed
    32. Angel PM, Bayoumi AS, Hinton RB, Ru Su Y, Bichell D, Mayer JE, Scott Baldwin H, Caprioli RM. MALDI Imaging Mass Spectrometry as a Lipidomic Approach to Heart Valve Research. J Heart Valve Dis. 2016 03; 25(2):240-252. PMID: 27989075.
      View in: PubMed
    33. Paglia G, Stocchero M, Cacciatore S, Lai S, Angel P, Alam MT, Keller M, Ralser M, Astarita G. Unbiased Metabolomic Investigation of Alzheimer's Disease Brain Points to Dysregulation of Mitochondrial Aspartate Metabolism. J Proteome Res. 2016 Feb 05; 15(2):608-18. PMID: 26717242.
      View in: PubMed
    34. Moses BS, Slone WL, Thomas P, Evans R, Piktel D, Angel PM, Walsh CM, Cantrell PS, Rellick SL, Martin KH, Simpkins JW, Gibson LF. Bone marrow microenvironment modulation of acute lymphoblastic leukemia phenotype. Exp Hematol. 2016 Jan; 44(1):50-9.e1-2. PMID: 26407636.
      View in: PubMed
    35. Paglia G, Angel P, Williams JP, Richardson K, Olivos HJ, Thompson JW, Menikarachchi L, Lai S, Walsh C, Moseley A, Plumb RS, Grant DF, Palsson BO, Langridge J, Geromanos S, Astarita G. Ion mobility-derived collision cross section as an additional measure for lipid fingerprinting and identification. Anal Chem. 2015 Jan 20; 87(2):1137-44. PMID: 25495617.
      View in: PubMed
    36. Wattacheril J, Seeley EH, Angel P, Chen H, Bowen BP, Lanciault C, Caprioli RM, Abumrad N, Flynn CR. Differential intrahepatic phospholipid zonation in simple steatosis and nonalcoholic steatohepatitis. PLoS One. 2013; 8(2):e57165. PMID: 23451176.
      View in: PubMed
    37. Goudy S, Angel P, Jacobs B, Hill C, Mainini V, Smith AL, Kousa YA, Caprioli R, Prince LS, Baldwin S, Schutte BC. Cell-autonomous and non-cell-autonomous roles for IRF6 during development of the tongue. PLoS One. 2013; 8(2):e56270. PMID: 23451037.
      View in: PubMed
    38. Angel PM, Caprioli RM. Matrix-assisted laser desorption ionization imaging mass spectrometry: in situ molecular mapping. Biochemistry. 2013 Jun 04; 52(22):3818-28. PMID: 23259809.
      View in: PubMed
    39. Angel PM, Spraggins JM, Baldwin HS, Caprioli R. Enhanced sensitivity for high spatial resolution lipid analysis by negative ion mode matrix assisted laser desorption ionization imaging mass spectrometry. Anal Chem. 2012 Feb 07; 84(3):1557-64. PMID: 22243218.
      View in: PubMed
    40. Gerwe BA, Angel PM, West FD, Hasneen K, Young A, Orlando R, Stice SL. Membrane proteomic signatures of karyotypically normal and abnormal human embryonic stem cell lines and derivatives. Proteomics. 2011 Jun; 11(12):2515-27. PMID: 21598385.
      View in: PubMed
    41. Mainini V, Angel PM, Magni F, Caprioli RM. Detergent enhancement of on-tissue protein analysis by matrix-assisted laser desorption/ionization imaging mass spectrometry. Rapid Commun Mass Spectrom. 2011 Jan 15; 25(1):199-204. PMID: 21157864.
      View in: PubMed
    42. Angel PM, Nusinow D, Brown CB, Violette K, Barnett JV, Zhang B, Baldwin HS, Caprioli RM. Networked-based characterization of extracellular matrix proteins from adult mouse pulmonary and aortic valves. J Proteome Res. 2011 Feb 04; 10(2):812-23. PMID: 21133377.
      View in: PubMed
    43. Chaurand P, Cornett DS, Angel PM, Caprioli RM. From whole-body sections down to cellular level, multiscale imaging of phospholipids by MALDI mass spectrometry. Mol Cell Proteomics. 2011 Feb; 10(2):O110.004259. PMID: 20736411.
      View in: PubMed
    44. Reyzer ML, Chaurand P, Angel PM, Caprioli RM. Direct molecular analysis of whole-body animal tissue sections by MALDI imaging mass spectrometry. Methods Mol Biol. 2010; 656:285-301. PMID: 20680598.
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    45. Orlando R, Lim JM, Atwood JA, Angel PM, Fang M, Aoki K, Alvarez-Manilla G, Moremen KW, York WS, Tiemeyer M, Pierce M, Dalton S, Wells L. IDAWG: Metabolic incorporation of stable isotope labels for quantitative glycomics of cultured cells. J Proteome Res. 2009 Aug; 8(8):3816-23. PMID: 19449840.
      View in: PubMed
    46. Lim JM, Aoki K, Angel P, Garrison D, King D, Tiemeyer M, Bergmann C, Wells L. Mapping glycans onto specific N-linked glycosylation sites of Pyrus communis PGIP redefines the interface for EPG-PGIP interactions. J Proteome Res. 2009 Feb; 8(2):673-80. PMID: 19072240.
      View in: PubMed
    47. Angel PM, Orlando R. Quantitative carbamylation as a stable isotopic labeling method for comparative proteomics. Rapid Commun Mass Spectrom. 2007; 21(10):1623-34. PMID: 17465008.
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    48. Angel PM, Lim JM, Wells L, Bergmann C, Orlando R. A potential pitfall in 18O-based N-linked glycosylation site mapping. Rapid Commun Mass Spectrom. 2007; 21(5):674-82. PMID: 17279607.
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    49. Angel PM, Orlando R. Trypsin is the primary mechanism by which the (18)O isotopic label is lost in quantitative proteomic studies. Anal Biochem. 2006 Dec 01; 359(1):26-34. PMID: 17046705.
      View in: PubMed
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