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David Maria Cachia

Title
InstitutionMedical University of South Carolina
DepartmentNeurosurgery
AddressP.O. Box MSC 606
HE314F
Clinical Science Bldg. - 96 Jonathan Lucas St.
Phone843-792-2568
Fax843-792-2234
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    Collapse Overview 
    Collapse studies/trials
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    Brain Tumor, Cancer, Women-s Health, Glioblastoma, Men-s Health

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ajinkya S, Fox J, Houston P, Greenblatt A, Lekoubou A, Lindhorst S, Cachia D, Olar A, Kutluay E. Seizures in Patients With Metastatic Brain Tumors: Prevalence, Clinical Characteristics, and Features on EEG. J Clin Neurophysiol. 2021 Mar 01; 38(2):143-148. PMID: 31856045.
      View in: PubMed
    2. Frankel BM, Cachia D, Patel SJ, Das A. Analysis of the P53N a Novel Protein Encoded on Chromosome 22q12.1-12.3 in Glioblastomas and Ependymomas Specimens. J Mol Neurosci. 2021 Feb 17. PMID: 33595778.
      View in: PubMed
    3. Alshareef MA, Klapthor G, Lowe SR, Barley J, Cachia D, Frankel BM. Strategies for posterior-only minimally invasive surgery in thoracolumbar metastatic epidural spinal cord compression. Surg Neurol Int. 2020; 11:462. PMID: 33408947.
      View in: PubMed
    4. Cloughesy TF, Petrecca K, Walbert T, Butowski N, Salacz M, Perry J, Damek D, Bota D, Bettegowda C, Zhu JJ, Iwamoto F, Placantonakis D, Kim L, Elder B, Kaptain G, Cachia D, Moshel Y, Brem S, Piccioni D, Landolfi J, Chen CC, Gruber H, Rao AR, Hogan D, Accomando W, Ostertag D, Montellano TT, Kheoh T, Kabbinavar F, Vogelbaum MA. Effect of Vocimagene Amiretrorepvec in Combination With Flucytosine vs Standard of Care on Survival Following Tumor Resection in Patients With Recurrent High-Grade Glioma: A Randomized Clinical Trial. JAMA Oncol. 2020 12 01; 6(12):1939-1946. PMID: 33119048.
      View in: PubMed
    5. Das A, Alshareef M, Porto GBF, Infinger LK, Vandergrift WA, Lindhorst SM, Varma AK, Patel SJ, Cachia D. Preconditioning with INC280 and LDK378 drugs sensitizes MGMT-unmethylated glioblastoma to temozolomide: Pre-clinical assessment. J Neurol Sci. 2020 Nov 15; 418:117102. PMID: 32866816.
      View in: PubMed
    6. Das A, Henderson FC, Alshareef M, Porto GBF, Kanginakudru I, Infinger LK, Vandergrift WA, Lindhorst SM, Varma AK, Patel SJ, Cachia D. MGMT-inhibitor in combination with TGF-ßRI inhibitor or CDK 4/6 inhibitor increases temozolomide sensitivity in temozolomide-resistant glioblastoma cells. Clin Transl Oncol. 2021 Mar; 23(3):612-619. PMID: 32710211.
      View in: PubMed
    7. Das A, Martinez Santos JL, Alshareef M, Porto GBF, Infinger LK, Vandergrift WA, Lindhorst SM, Varma AK, Patel SJ, Cachia D. In Vitro Effect of Dovitinib (TKI258), a Multi-Target Angiokinase Inhibitor on Aggressive Meningioma Cells. Cancer Invest. 2020 Jul; 38(6):349-355. PMID: 32441531.
      View in: PubMed
    8. Frankel BM, Cachia D, Patel SJ, Das A. Targeting Subventricular Zone Progenitor Cells with Intraventricular Liposomal Encapsulated Cytarabine in Patients with Secondary Glioblastoma : A Report of Two Cases. SN Compr Clin Med. 2020 Jun; 2(6):836-843. PMID: 32704621.
      View in: PubMed
    9. Nam JY, Gilbert A, Cachia D, Mandel J, Fuller GN, Penas-Prado M, de Groot J, Kamiya-Matsuoka C. Pineal parenchymal tumor of intermediate differentiation: a single-institution experience. Neurooncol Pract. 2020 Dec; 7(6):613-619. PMID: 33312675.
      View in: PubMed
    10. Frankel BM, Cachia D, Patel SJ, Das A. Analysis of P78: A Novel Cytoplasmic Membrane-Associated Protein Encoded on Chromosome 19q13.3 in Glioma Specimens. J Mol Neurosci. 2020 Sep; 70(9):1415-1424. PMID: 32367506.
      View in: PubMed
    11. Das A, Alshareef M, Martinez Santos JL, Porto GBF, McDonald DG, Infinger LK, Vandergrift WA, Lindhorst SM, Varma AK, Patel SJ, Cachia D. Evaluating anti-tumor activity of palbociclib plus radiation in anaplastic and radiation-induced meningiomas: pre-clinical investigations. Clin Transl Oncol. 2020 Nov; 22(11):2017-2025. PMID: 32253706.
      View in: PubMed
    12. Das A, Alshareef M, Henderson F, Martinez Santos JL, Vandergrift WA, Lindhorst SM, Varma AK, Infinger L, Patel SJ, Cachia D. Ganoderic acid A/DM-induced NDRG2 over-expression suppresses high-grade meningioma growth. Clin Transl Oncol. 2020 Jul; 22(7):1138-1145. PMID: 31732915.
      View in: PubMed
    13. Fox J, Ajinkya S, Greenblatt A, Houston P, Lekoubou A, Lindhorst S, Cachia D, Olar A, Kutluay E. Clinical characteristics, EEG findings and implications of status epilepticus in patients with brain metastases. J Neurol Sci. 2019 Dec 15; 407:116538. PMID: 31644990.
      View in: PubMed
    14. Harrison RA, Anderson MD, Cachia D, Kamiya-Matsuoka C, Weathers SS, O'Brien BJ, Penas-Prado M, Yung WKA, Wu J, Yuan Y, de Groot JF. Clinical trial participation of patients with glioblastoma at The University of Texas MD Anderson Cancer Center. Eur J Cancer. 2019 05; 112:83-93. PMID: 30951926.
      View in: PubMed
    15. Fox J, Ajinkya S, Houston P, Lindhorst S, Cachia D, Olar A, Kutluay E. Seizures in patents with primary central nervous system lymphoma: Prevalence and associated features. J Neurol Sci. 2019 May 15; 400:34-38. PMID: 30901566.
      View in: PubMed
    16. D'Angelo F, Ceccarelli M, Garofano L, Zhang J, Frattini V, Caruso FP, Lewis G, Alfaro KD, Bauchet L, Berzero G, Cachia D, Cangiano M, Capelle L, de Groot J, DiMeco F, Ducray F, Farah W, Finocchiaro G, Goutagny S, Kamiya-Matsuoka C, Lavarino C, Loiseau H, Lorgis V, Marras CE, McCutcheon I, Nam DH, Ronchi S, Saletti V, Seizeur R, Slopis J, Suñol M, Vandenbos F, Varlet P, Vidaud D, Watts C, Tabar V, Reuss DE, Kim SK, Meyronet D, Mokhtari K, Salvador H, Bhat KP, Eoli M, Sanson M, Lasorella A, Iavarone A. The molecular landscape of glioma in patients with Neurofibromatosis 1. Nat Med. 2019 01; 25(1):176-187. PMID: 30531922.
      View in: PubMed
    17. Burton C, Das A, McDonald D, Vandergrift WA, Patel SJ, Cachia D, Bartee E. Oncolytic myxoma virus synergizes with standard of care for treatment of glioblastoma multiforme. Oncolytic Virother. 2018; 7:107-116. PMID: 30538967.
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    18. Das A, Henderson F, Lowe S, Wallace GC, Vandergrift WA, Lindhorst SM, Varma AK, Infinger LK, Giglio P, Banik NL, Patel SJ, Cachia D. Single agent efficacy of the HDAC inhibitor DATS in preclinical models of glioblastoma. Cancer Chemother Pharmacol. 2018 12; 82(6):945-952. PMID: 30209569.
      View in: PubMed
    19. Cachia D, Johnson DR, Kaufmann TJ, Lowe S, Andersen S, Olar A, Cooper SL, Frankel BM, Gilbert MR. Case-based review: ependymomas in adults. Neurooncol Pract. 2018 Aug; 5(3):142-153. PMID: 31386035.
      View in: PubMed
    20. Mandel JJ, Yust-Katz S, Patel AJ, Cachia D, Liu D, Park M, Yuan Y, Kent TA, de Groot JF. Inability of positive phase II clinical trials of investigational treatments to subsequently predict positive phase III clinical trials in glioblastoma. Neuro Oncol. 2018 01 10; 20(1):113-122. PMID: 29016865.
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    21. Yust Katz S, Cachia D, Kamiya-Matsuoka C, Olar A, Theeler B, Penas Prado M, Gilbert MR, Armstrong T. Corrigendum to 'Ependymomas arising outside of the central nervous system: A case series and literature review' [J Clin Neurosci 47 (2018) 202-207]. J Clin Neurosci. 2018 05; 51:105. PMID: 29295763.
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    22. Yust Katz S, Cachia D, Kamiya-Matsuoka C, Olar A, Theeler B, Penas Prado M, Gilbert MR, Armstrong T. Ependymomas arising outside of the central nervous system: A case series and literature review. J Clin Neurosci. 2018 Jan; 47:202-207. PMID: 29054328.
      View in: PubMed
    23. Cachia D, Elshafeey NA, Kamiya-Matsuoka C, Hatami M, Alfaro-Munoz KD, Mandel JJ, Colen R, DeGroot JF. Radiographic patterns of progression with associated outcomes after bevacizumab therapy in glioblastoma patients. J Neurooncol. 2017 Oct; 135(1):75-81. PMID: 28702781.
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    24. Pinnix CC, Chi L, Jabbour EJ, Milgrom SA, Smith GL, Daver N, Garg N, Cykowski MD, Fuller G, Cachia D, Kamiya-Matsuoka C, Woodman K, Dinardo C, Jain N, Kadia TM, Pemmaraju N, Ohanian M, Konopleva M, Kantarjian HM, Dabaja BS. Dorsal column myelopathy after intrathecal chemotherapy for leukemia. Am J Hematol. 2017 Feb; 92(2):155-160. PMID: 27874212.
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    25. Kamiya-Matsuoka C, Cachia D, Waguespack SG, Crane CH, Mahajan A, Brown PD, Nam JY, McCutcheon IE, Penas-Prado M. Radiotherapy with concurrent temozolomide for the management of extraneural metastases in pituitary carcinoma. Pituitary. 2016 Aug; 19(4):415-21. PMID: 27106209.
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    26. Mandel JJ, Cachia D, Liu D, Wilson C, Aldape K, Fuller G, de Groot JF. Impact of IDH1 mutation status on outcome in clinical trials for recurrent glioblastoma. J Neurooncol. 2016 08; 129(1):147-54. PMID: 27270908.
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    27. Day J, Yust-Katz S, Cachia D, Wefel J, Katz LH, Tremont I, Bulbeck H, Armstrong T, Rooney AG. Interventions for the management of fatigue in adults with a primary brain tumour. Cochrane Database Syst Rev. 2016 Apr 13; 4:CD011376. PMID: 27074263.
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    28. Strickland BA, Cachia D, Jalali A, Cykowski MD, Penas-Prado M, Langford LA, Li J, Shah K, Weinberg JS. Spinal Anaplastic Oligodendroglioma With Oligodendrogliomatosis: Molecular Markers and Management: Case Report. Neurosurgery. 2016 Mar; 78(3):E466-73. PMID: 26352098.
      View in: PubMed
    29. Das A, McDonald DG, Dixon-Mah YN, Jacqmin DJ, Samant VN, Vandergrift WA, Lindhorst SM, Cachia D, Varma AK, Vanek KN, Banik NL, Jenrette JM, Raizer JJ, Giglio P, Patel SJ. RIP1 and RIP3 complex regulates radiation-induced programmed necrosis in glioblastoma. Tumour Biol. 2016 Jun; 37(6):7525-34. PMID: 26684801.
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    30. Das A, Cheng RR, Hilbert ML, Dixon-Moh YN, Decandio M, Vandergrift WA, Banik NL, Lindhorst SM, Cachia D, Varma AK, Patel SJ, Giglio P. Synergistic Effects of Crizotinib and Temozolomide in Experimental FIG-ROS1 Fusion-Positive Glioblastoma. Cancer Growth Metastasis. 2015; 8:51-60. PMID: 26648752.
      View in: PubMed
    31. Alfaraj WA, Cachia D, Tummala S, Thomas SK, Manasanch EE. Severe peripheral neuropathy following carfilzomib, rituximab, and dexamethasone for initial treatment of Waldenström's macroglobulinemia. Ann Hematol. 2016 Jan; 95(2):347-8. PMID: 26432713.
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    32. Cachia D, Kamiya-Matsuoka C, Mandel JJ, Olar A, Cykowski MD, Armstrong TS, Fuller GN, Gilbert MR, De Groot JF. Primary and secondary gliosarcomas: clinical, molecular and survival characteristics. J Neurooncol. 2015 Nov; 125(2):401-10. PMID: 26354773.
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    33. Kamiya-Matsuoka C, Cachia D, Yust-Katz S, Rodriguez YA, Garciarena P, Rodarte EM, Tremont-Lukats IW. Ischemic stroke in patients with gliomas at The University of Texas-M.D. Anderson Cancer Center. J Neurooncol. 2015 Oct; 125(1):143-8. PMID: 26272599.
      View in: PubMed
    34. Cachia D, Makhija M, Smith T. Cough and confusion in an elderly man with chronic lymphocytic leukemia. J Clin Neurosci. 2015 Dec; 22(12):1963,1996. PMID: 26870858.
      View in: PubMed
    35. Cachia D, Kamiya-Matsuoka C, Pinnix CC, Chi L, Kantarjian HM, Cortes JE, Daver N, Woodman K. Myelopathy following intrathecal chemotherapy in adults: a single institution experience. J Neurooncol. 2015 Apr; 122(2):391-8. PMID: 25666482.
      View in: PubMed
    36. Cachia D, Wani K, Penas-Prado M, Olar A, McCutcheon IE, Benjamin RS, Armstrong TS, Gilbert MR, Aldape KD. C11orf95-RELA fusion present in a primary supratentorial ependymoma and recurrent sarcoma. Brain Tumor Pathol. 2015 Apr; 32(2):105-11. PMID: 25388523.
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    37. Cachia D, Smith T, Paydarfar D, Pomorska G. A case of early-onset rapidly progressive dementia. JAMA Neurol. 2014 Nov; 71(11):1445-9. PMID: 25265527.
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    38. Cachia D, Prado MP, Theeler B, Hamilton J, McCutcheon I, Fuller GN. Synchronous rosette-forming glioneuronal tumor and diffuse astrocytoma with molecular characterization: a case report. Clin Neuropathol. 2014 Nov-Dec; 33(6):407-11. PMID: 24986181.
      View in: PubMed
    39. Cachia D, Singh C, Tetzlaff MT, Penas-Prado M. Middle cerebral artery territory infarct due to Cryptococcus infectionstitle: an uncommon indication for cerebrospinal fluid analysis in stroke patients. Diagn Cytopathol. 2015 Aug; 43(8):632-4. PMID: 25352313.
      View in: PubMed
    40. Kamiya-Matsuoka C, Cachia D, Olar A, Armstrong TS, Gilbert MR. Primary brain tumors and posterior reversible encephalopathy syndrome. Neurooncol Pract. 2014 Dec; 1(4):184-190. PMID: 26034631.
      View in: PubMed
    41. Mandel JJ, Yust-Katz S, Cachia D, Wu J, Liu D, de Groot JF, Yung AW, Gilbert MR. Leptomeningeal dissemination in glioblastoma; an inspection of risk factors, treatment, and outcomes at a single institution. J Neurooncol. 2014 Dec; 120(3):597-605. PMID: 25168214.
      View in: PubMed
    42. Deeb W, Cachia D, Quinn C, Salameh J. Peripheral neuropathy after hair dye exposure: a case report. J Clin Neuromuscul Dis. 2014 Jun; 15(4):161-3. PMID: 24872215.
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    43. Cachia D, Izzy S, Berriosmorales I, Ionete C. Drug-induced thrombocytopenia secondary to natalizumab treatment. BMJ Case Rep. 2014 May 30; 2014. PMID: 24879724.
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    44. Cachia D, Stine C. Child Neurology: cognitive delay in a 7-year-old girl. Neurology. 2013 Nov 12; 81(20):e148-50. PMID: 24218321.
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    45. Cachia D, Izzy S, Smith T, Ionete C. A rare presentation of hypertrophic olivary degeneration secondary to primary central nervous system lymphoma. JAMA Neurol. 2013 Sep 01; 70(9):1192-3. PMID: 23857254.
      View in: PubMed
    46. Cachia D, Izzy S, Ionete C, Salameh J. Brachial amyotrophic diplegia in the setting of complete HIV viral load suppression. BMJ Case Rep. 2012 Dec 06; 2012. PMID: 23220836.
      View in: PubMed
    47. Cachia D, Alderson L, Smith T, Yunus S. Widely metastatic meningioma. Arch Neurol. 2012 Oct; 69(10):1372-3. PMID: 22776979.
      View in: PubMed
    48. Cachia D, Swearer J, Ferguson W, Moonis M. Selective cognitive patterns resulting from bilateral hippocampal ischemia. Arch Med Sci. 2011 Feb; 7(1):168-72. PMID: 22291752.
      View in: PubMed
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