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Kenneth A Christensen

TitleAssociate Professor
InstitutionClemson University
DepartmentDepartment of Chemistry
Address223 Hunter Hall
Clemson, South Carolina 29634
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Finnell JG, Tsang TM, Cryan L, Garrard S, Lee SL, Ackroyd PC, Rogers MS, Christensen KA. A Canstatin-Derived Peptide Provides Insight into the Role of Capillary Morphogenesis Gene 2 in Angiogenic Regulation and Matrix Uptake. ACS Chem Biol. 2020 Feb 13. PMID: 32003961.
      View in: PubMed
    2. G-Doyagüez E, Carrero P, Madrona A, Rodriguez-Salamanca P, Martínez-Gualda B, Camarasa MJ, Jimeno ML, Bennallack PR, Finnell JG, Tsang TM, Christensen KA, San-Félix A, Rogers MS. Galloyl Carbohydrates with Antiangiogenic Activity Mediated by Capillary Morphogenesis Gene 2 (CMG2) Protein Binding. J Med Chem. 2019 Apr 25; 62(8):3958-3970. PMID: 30964669.
      View in: PubMed
    3. Voyton CM, Choi J, Qiu Y, Morris MT, Ackroyd PC, Morris JC, Christensen KA. A Microfluidic-Based Microscopy Platform for Continuous Interrogation of Trypanosoma brucei during Environmental Perturbation. Biochemistry. 2019 02 19; 58(7):875-882. PMID: 30638014.
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    4. Voyton CM, Qiu Y, Morris MT, Ackroyd PC, Suryadi J, Crowe L, Morris JC, Christensen KA. A FRET flow cytometry method for monitoring cytosolic and glycosomal glucose in living kinetoplastid parasites. PLoS Negl Trop Dis. 2018 05; 12(5):e0006523. PMID: 29851949.
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    5. Voyton CM, Morris MT, Ackroyd PC, Morris JC, Christensen KA. FRET Flow Cytometry-Based High Throughput Screening Assay To Identify Disrupters of Glucose Levels in Trypanosoma brucei. ACS Infect Dis. 2018 07 13; 4(7):1058-1066. PMID: 29741365.
      View in: PubMed
    6. Gordhan HM, Milanes JE, Qiu Y, Golden JE, Christensen KA, Morris JC, Whitehead DC. A targeted delivery strategy for the development of potent trypanocides. Chem Commun (Camb). 2017 Aug 11; 53(62):8735-8738. PMID: 28726862.
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    7. Jia Z, Ackroyd C, Han T, Agrawal V, Liu Y, Christensen K, Dominy B. Effects from metal ion in tumor endothelial marker 8 and anthrax protective antigen: BioLayer Interferometry experiment and molecular dynamics simulation study. J Comput Chem. 2017 06 05; 38(15):1183-1190. PMID: 28437008.
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    8. Lin S, Voyton C, Morris MT, Ackroyd PC, Morris JC, Christensen KA. pH regulation in glycosomes of procyclic form Trypanosoma brucei. J Biol Chem. 2017 05 12; 292(19):7795-7805. PMID: 28348078.
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    9. Schadock-Hewitt AJ, Pittman JJ, Christensen KA, Marcus RK. Head group-functionalized poly(ethyleneglycol)-lipid (PEG-lipid) surface modification for highly selective analyte extractions on capillary-channeled polymer (C-CP) fibers. Analyst. 2014 May 07; 139(9):2108-13. PMID: 24503581.
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    10. Dukes KD, Christensen KA, Chumanov G. Core-shell silver nanoparticles for optical labeling of cells. Anal Biochem. 2014 Aug 01; 458:43-8. PMID: 24755004.
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    11. Lin S, Morris MT, Ackroyd PC, Morris JC, Christensen KA. Peptide-targeted delivery of a pH sensor for quantitative measurements of intraglycosomal pH in live Trypanosoma brucei. Biochemistry. 2013 May 28; 52(21):3629-37. PMID: 23651061.
      View in: PubMed
    12. Cryan LM, Habeshian KA, Caldwell TP, Morris MT, Ackroyd PC, Christensen KA, Rogers MS. Identification of small molecules that inhibit the interaction of TEM8 with anthrax protective antigen using a FRET assay. J Biomol Screen. 2013 Jul; 18(6):714-25. PMID: 23479355.
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    13. Cryan LM, Bazinet L, Habeshian KA, Cao S, Clardy J, Christensen KA, Rogers MS. 1,2,3,4,6-Penta-O-galloyl-ß-D-glucopyranose inhibits angiogenesis via inhibition of capillary morphogenesis gene 2. J Med Chem. 2013 Mar 14; 56(5):1940-5. PMID: 23394144.
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    14. Fernando LP, Kandel PK, Ackroyd PC, Christensen KA. The relative brightness of PEG lipid-conjugated polymer nanoparticles as fluid-phase markers in live cells. Anal Bioanal Chem. 2012 Dec; 404(10):3003-14. PMID: 23052882.
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    15. Wang F, Widejko RG, Yang Z, Nguyen KT, Chen H, Fernando LP, Christensen KA, Anker JN. Surface-enhanced raman scattering detection of pH with silica-encapsulated 4-mercaptobenzoic acid-functionalized silver nanoparticles. Anal Chem. 2012 Sep 18; 84(18):8013-9. PMID: 22881392.
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    16. Rogers MS, Cryan LM, Habeshian KA, Bazinet L, Caldwell TP, Ackroyd PC, Christensen KA. A FRET-based high throughput screening assay to identify inhibitors of anthrax protective antigen binding to capillary morphogenesis gene 2 protein. PLoS One. 2012; 7(6):e39911. PMID: 22768167.
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    17. Chaurra A, Gutzman BM, Taylor E, Ackroyd PC, Christensen KA. Lucifer Yellow as a live cell fluorescent probe for imaging water transport in subcellular organelles. Appl Spectrosc. 2011 Jan; 65(1):20-5. PMID: 21211149.
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    18. Kandel PK, Fernando LP, Ackroyd PC, Christensen KA. Incorporating functionalized polyethylene glycol lipids into reprecipitated conjugated polymer nanoparticles for bioconjugation and targeted labeling of cells. Nanoscale. 2011 Mar; 3(3):1037-45. PMID: 21152603.
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    19. Dodson HC, Lyda TA, Chambers JW, Morris MT, Christensen KA, Morris JC. Quercetin, a fluorescent bioflavanoid, inhibits Trypanosoma brucei hexokinase 1. Exp Parasitol. 2011 Feb; 127(2):423-8. PMID: 20971104.
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    20. Fernando LP, Kandel PK, Yu J, McNeill J, Ackroyd PC, Christensen KA. Mechanism of cellular uptake of highly fluorescent conjugated polymer nanoparticles. Biomacromolecules. 2010 Oct 11; 11(10):2675-82. PMID: 20863132.
      View in: PubMed
    21. Bhut BV, Christensen KA, Husson SM. Membrane chromatography: protein purification from E. coli lysate using newly designed and commercial anion-exchange stationary phases. J Chromatogr A. 2010 Jul 23; 1217(30):4946-57. PMID: 20554285.
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    22. Luo PG, Wang H, Gu L, Lu F, Lin Y, Christensen KA, Yang ST, Sun YP. Selective interactions of sugar-functionalized single-walled carbon nanotubes with Bacillus spores. ACS Nano. 2009 Dec 22; 3(12):3909-16. PMID: 19911831.
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    23. Wu C, Bull B, Christensen K, McNeill J. Ratiometric single-nanoparticle oxygen sensors for biological imaging. Angew Chem Int Ed Engl. 2009; 48(15):2741-5. PMID: 19253320.
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    24. Wu C, Bull B, Szymanski C, Christensen K, McNeill J. Multicolor conjugated polymer dots for biological fluorescence imaging. ACS Nano. 2008 Nov 25; 2(11):2415-23. PMID: 19206410.
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    25. Rogers MS, Christensen KA, Birsner AE, Short SM, Wigelsworth DJ, Collier RJ, D'Amato RJ. Mutant anthrax toxin B moiety (protective antigen) inhibits angiogenesis and tumor growth. Cancer Res. 2007 Oct 15; 67(20):9980-5. PMID: 17942931.
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    26. Evanoff DD, Heckel J, Caldwell TP, Christensen KA, Chumanov G. Monitoring DPA release from a single germinating Bacillus subtilis endospore via surface-enhanced Raman scattering microscopy. J Am Chem Soc. 2006 Oct 04; 128(39):12618-9. PMID: 17002334.
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    27. Shaughnessy LM, Hoppe AD, Christensen KA, Swanson JA. Membrane perforations inhibit lysosome fusion by altering pH and calcium in Listeria monocytogenes vacuoles. Cell Microbiol. 2006 May; 8(5):781-92. PMID: 16611227.
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    28. Daniels JK, Caldwell TP, Christensen KA, Chumanov G. Monitoring the kinetics of Bacillus subtilis endospore germination via surface-enhanced Raman scattering spectroscopy. Anal Chem. 2006 Mar 01; 78(5):1724-9. PMID: 16503629.
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    29. Christensen KA, Krantz BA, Collier RJ. Assembly and disassembly kinetics of anthrax toxin complexes. Biochemistry. 2006 Feb 21; 45(7):2380-6. PMID: 16475827.
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    30. Qa'dan M, Christensen KA, Zhang L, Roberts TM, Collier RJ. Membrane insertion by anthrax protective antigen in cultured cells. Mol Cell Biol. 2005 Jul; 25(13):5492-8. PMID: 15964805.
      View in: PubMed
    31. Christensen KA, Krantz BA, Melnyk RA, Collier RJ. Interaction of the 20 kDa and 63 kDa fragments of anthrax protective antigen: kinetics and thermodynamics. Biochemistry. 2005 Jan 25; 44(3):1047-53. PMID: 15654761.
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    32. Krantz BA, Trivedi AD, Cunningham K, Christensen KA, Collier RJ. Acid-induced unfolding of the amino-terminal domains of the lethal and edema factors of anthrax toxin. J Mol Biol. 2004 Nov 26; 344(3):739-56. PMID: 15533442.
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    33. Pimental RA, Christensen KA, Krantz BA, Collier RJ. Anthrax toxin complexes: heptameric protective antigen can bind lethal factor and edema factor simultaneously. Biochem Biophys Res Commun. 2004 Sep 10; 322(1):258-62. PMID: 15313199.
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    34. Wigelsworth DJ, Krantz BA, Christensen KA, Lacy DB, Juris SJ, Collier RJ. Binding stoichiometry and kinetics of the interaction of a human anthrax toxin receptor, CMG2, with protective antigen. J Biol Chem. 2004 May 28; 279(22):23349-56. PMID: 15044490.
      View in: PubMed
    35. Hoppe A, Christensen K, Swanson JA. Fluorescence resonance energy transfer-based stoichiometry in living cells. Biophys J. 2002 Dec; 83(6):3652-64. PMID: 12496132.
      View in: PubMed
    36. Christensen KA, Myers JT, Swanson JA. pH-dependent regulation of lysosomal calcium in macrophages. J Cell Sci. 2002 Feb 01; 115(Pt 3):599-607. PMID: 11861766.
      View in: PubMed
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