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Frank Alexis

TitleAssistant Professor
InstitutionClemson University
DepartmentDepartment of Bioengineering
Address301 Rhodes Hall
Clemson, South Carolina 29634
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Lex TR, Brummel BR, Attia MF, Giambalvo LN, Lee KG, Van Horn BA, Whitehead DC, Alexis F. Iodinated Polyesters with Enhanced X-ray Contrast Properties for Biomedical Imaging. Sci Rep. 2020 Jan 30; 10(1):1508. PMID: 32001741.
      View in: PubMed
    2. Moia VM, Leal Portilho F, Almeida Pádua T, Barbosa Corrêa L, Ricci-Junior E, Cruz Rosas E, Magalhaes Rebelo Alencar L, Savio Mendes Sinfronio F, Sampson A, Hussain Iram S, Alexis F, de OliveiraHenriques MD, Santos-Oliveira R. Lycopene used as Anti-inflammatory Nanodrug for the Treatment of Rheumathoid Arthritis: Animal assay, Pharmacokinetics, ABC Transporter and Tissue Deposition. Colloids Surf B Biointerfaces. 2020 Jan 20; 188:110814. PMID: 31982791.
      View in: PubMed
    3. Helal-Neto E, Barros AODS, Saldanha-Gama R, Brandão-Costa R, Alencar LMR, Santos CCD, Martínez-Máñez R, Ricci-Junior E, Alexis F, Morandi V, Barja-Fidalgo C, Santos-Oliveira R. Molecular and Cellular Risk Assessment of Healthy Human Cells and Cancer Human Cells Exposed to Nanoparticles. Int J Mol Sci. 2019 Dec 28; 21(1). PMID: 31905708.
      View in: PubMed
    4. Attia MF, Swasy MI, Ateia M, Alexis F, Whitehead DC. Periodic mesoporous organosilica nanomaterials for rapid capture of VOCs. Chem Commun (Camb). 2020 Jan 14; 56(4):607-610. PMID: 31830163.
      View in: PubMed
    5. Machado RCL, Alexis F, De Sousa AFB. Nanostructured and Photochromic Material for Environmental Detection of Metal Ions. Molecules. 2019 Nov 21; 24(23). PMID: 31766481.
      View in: PubMed
    6. Valerio MS, Alexis F, Kirkwood KL. Functionalized nanoparticles containing MKP-1 agonists reduce periodontal bone loss. J Periodontol. 2019 Aug; 90(8):894-902. PMID: 30811602.
      View in: PubMed
    7. Attia MF, Brummel BR, Lex TR, Van Horn BA, Whitehead DC, Alexis F. Recent Advances in Polyesters for Biomedical Imaging. Adv Healthc Mater. 2018 11; 7(22):e1800798. PMID: 30295005.
      View in: PubMed
    8. Swasy MI, Campbell ML, Brummel BR, Guerra FD, Attia MF, Smith GD, Alexis F, Whitehead DC. Poly(amine) modified kaolinite clay for VOC capture. Chemosphere. 2018 Dec; 213:19-24. PMID: 30205272.
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    9. Guerra FD, Attia MF, Whitehead DC, Alexis F. Nanotechnology for Environmental Remediation: Materials and Applications. Molecules. 2018 Jul 18; 23(7). PMID: 30021974.
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    10. Chen H, Wang F, Moore T, Qi B, Sulejmanovic D, Hwu SJ, Mefford OT, Alexis F, Anker JN. Bright X-ray and up-conversion nanophosphors annealed using encapsulated sintering agents for bioimaging applications. J Mater Chem B. 2017; 5(27):5412-5424. PMID: 29497532.
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    11. Casco M, Olsen T, Herbst A, Evans G, Rothermel T, Pruett L, Simionescu D, Visconti R, Alexis F. Iron Oxide Nanoparticles Stimulates Extra-Cellular Matrix Production in Cellular Spheroids. Bioengineering (Basel). 2017 Jan 21; 4(1). PMID: 28952483.
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    12. Olsen TR, Casco M, Herbst A, Evans G, Rothermel T, Pruett L, Reid J, Barry K, Jaeggli MP, Simionescu DT, Visconti RP, Alexis F. Longitudinal Stretching for Maturation of Vascular Tissues Using Magnetic Forces. Bioengineering (Basel). 2016 Nov 16; 3(4). PMID: 28952591.
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    13. Campbell ML, Guerra FD, Dhulekar J, Alexis F, Whitehead DC. Target-Specific Capture of Environmentally Relevant Gaseous Aldehydes and Carboxylic Acids with Functional Nanoparticles. Chemistry. 2015 Oct 12; 21(42):14834-42. PMID: 26331393.
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    14. Pridgen EM, Alexis F, Farokhzad OC. Polymeric nanoparticle drug delivery technologies for oral delivery applications. Expert Opin Drug Deliv. 2015; 12(9):1459-73. PMID: 25813361.
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    15. Olsen TR, Davis LL, Nicolau SE, Duncan CC, Whitehead DC, Van Horn BA, Alexis F. Non-invasive deep tissue imaging of iodine modified poly(caprolactone-co-1-4-oxepan-1,5-dione) using X-ray. Acta Biomater. 2015 Jul; 20:94-103. PMID: 25818945.
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    16. Alexis F. Nano-polypharmacy to treat tumors: coencapsulation of drug combinations using nanoparticle technology. Mol Ther. 2014 Jul; 22(7):1239-1240. PMID: 24981439.
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    17. Pridgen EM, Alexis F, Farokhzad OC. Polymeric nanoparticle technologies for oral drug delivery. Clin Gastroenterol Hepatol. 2014 Oct; 12(10):1605-10. PMID: 24981782.
      View in: PubMed
    18. Chen H, Qi B, Moore T, Wang F, Colvin DC, Sanjeewa LD, Gore JC, Hwu SJ, Mefford OT, Alexis F, Anker JN. Multifunctional yolk-in-shell nanoparticles for pH-triggered drug release and imaging. Small. 2014 Aug 27; 10(16):3364-70. PMID: 24753264.
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    19. Ilyinskii PO, Roy CJ, O'Neil CP, Browning EA, Pittet LA, Altreuter DH, Alexis F, Tonti E, Shi J, Basto PA, Iannacone M, Radovic-Moreno AF, Langer RS, Farokhzad OC, von Andrian UH, Johnston LP, Kishimoto TK. Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release. Vaccine. 2014 May 19; 32(24):2882-95. PMID: 24593999.
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    20. Chen H, Sulejmanovic D, Moore T, Colvin DC, Qi B, Mefford OT, Gore JC, Alexis F, Hwu SJ, Anker JN. Iron-Loaded Magnetic Nanocapsules for pH-Triggered Drug Release and MRI Imaging. Chem Mater. 2014 Mar 25; 26(6):2105-2112. PMID: 24748722.
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    21. Alexis F, Anker JN. Theranostic nanotechnologies: moving beyond imaging drug localization? Ther Deliv. 2014 Feb; 5(2):97-100. PMID: 24483186.
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    22. Mattix B, Moore T, Uvarov O, Pollard S, O'Donnell L, Park K, Horne D, Dhulekar J, Reese L, Nguyen D, Kraveka J, Burg K, Alexis F. EFFECTS OF POLYMERIC NANOPARTICLE SURFACE PROPERTIES ON INTERACTION WITH BRAIN TUMOR ENVIRONMENT. Nano Life. 2013 Dec 17; 3(4):1343003. PMID: 25110523.
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    23. Moore TL, Grimes SW, Lewis RL, Alexis F. Multilayered polymer-coated carbon nanotubes to deliver dasatinib. Mol Pharm. 2014 Jan 06; 11(1):276-82. PMID: 24294824.
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    24. Pridgen EM, Alexis F, Kuo TT, Levy-Nissenbaum E, Karnik R, Blumberg RS, Langer R, Farokhzad OC. Transepithelial transport of Fc-targeted nanoparticles by the neonatal fc receptor for oral delivery. Sci Transl Med. 2013 Nov 27; 5(213):213ra167. PMID: 24285486.
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    25. Moore T, Chen H, Morrison R, Wang F, Anker JN, Alexis F. Nanotechnologies for noninvasive measurement of drug release. Mol Pharm. 2014 Jan 06; 11(1):24-39. PMID: 24215280.
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    26. Mattix BM, Olsen TR, Casco M, Reese L, Poole JT, Zhang J, Visconti RP, Simionescu A, Simionescu DT, Alexis F. Janus magnetic cellular spheroids for vascular tissue engineering. Biomaterials. 2014 Jan; 35(3):949-60. PMID: 24183699.
      View in: PubMed
    27. Mattix B, Olsen TR, Gu Y, Casco M, Herbst A, Simionescu DT, Visconti RP, Kornev KG, Alexis F. Biological magnetic cellular spheroids as building blocks for tissue engineering. Acta Biomater. 2014 Feb; 10(2):623-9. PMID: 24176725.
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    28. Chen H, Qi B, Moore T, Colvin DC, Crawford T, Gore JC, Alexis F, Mefford OT, Anker JN. Synthesis of brightly PEGylated luminescent magnetic upconversion nanophosphors for deep tissue and dual MRI imaging. Small. 2014 Jan 15; 10(1):160-8. PMID: 23828629.
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    29. Podila R, Moore T, Alexis F, Rao A. Graphene coatings for biomedical implants. J Vis Exp. 2013 Mar 01; (73):e50276. PMID: 23486380.
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    30. Moore TL, Pitzer JE, Podila R, Wang X, Lewis RL, Grimes SW, Wilson JR, Skjervold E, Brown JM, Rao A, Alexis F. Multifunctional Polymer-Coated Carbon Nanotubes for Safe Drug Delivery. Part Part Syst Charact. 2013 Apr; 30(4):365-373. PMID: 27642231.
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    31. Chen H, Moore T, Qi B, Colvin DC, Jelen EK, Hitchcock DA, He J, Mefford OT, Gore JC, Alexis F, Anker JN. Monitoring pH-triggered drug release from radioluminescent nanocapsules with X-ray excited optical luminescence. ACS Nano. 2013 Feb 26; 7(2):1178-87. PMID: 23281651.
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    32. Chen H, Colvin DC, Qi B, Moore T, He J, Mefford OT, Alexis F, Gore JC, Anker JN. Magnetic and optical properties of multifunctional core-shell radioluminescence nanoparticles. J Mater Chem. 2012 Jul 07; 22(25):12802-12809. PMID: 24520183.
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    33. Xiao Z, Levy-Nissenbaum E, Alexis F, Lupták A, Teply BA, Chan JM, Shi J, Digga E, Cheng J, Langer R, Farokhzad OC. Engineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection. ACS Nano. 2012 Jan 24; 6(1):696-704. PMID: 22214176.
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    34. Stone R, Willi T, Rosen Y, Mefford OT, Alexis F. Targeted magnetic hyperthermia. Ther Deliv. 2011 Jun; 2(6):815-38. PMID: 22822511.
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    35. Alexis F, Pridgen EM, Langer R, Farokhzad OC. Nanoparticle technologies for cancer therapy. Handb Exp Pharmacol. 2010; (197):55-86. PMID: 20217526.
      View in: PubMed
    36. Alexis F, Basto P, Levy-Nissenbaum E, Radovic-Moreno AF, Zhang L, Pridgen E, Wang AZ, Marein SL, Westerhof K, Molnar LK, Farokhzad OC. HER-2-targeted nanoparticle-affibody bioconjugates for cancer therapy. ChemMedChem. 2008 Dec; 3(12):1839-43. PMID: 19012296.
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    37. Wang AZ, Bagalkot V, Vasilliou CC, Gu F, Alexis F, Zhang L, Shaikh M, Yuet K, Cima MJ, Langer R, Kantoff PW, Bander NH, Jon S, Farokhzad OC. Superparamagnetic iron oxide nanoparticle-aptamer bioconjugates for combined prostate cancer imaging and therapy. ChemMedChem. 2008 Sep; 3(9):1311-5. PMID: 18613203.
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    38. Alexis F, Pridgen E, Molnar LK, Farokhzad OC. Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol Pharm. 2008 Jul-Aug; 5(4):505-15. PMID: 18672949.
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    39. Zhang L, Chan JM, Gu FX, Rhee JW, Wang AZ, Radovic-Moreno AF, Alexis F, Langer R, Farokhzad OC. Self-assembled lipid--polymer hybrid nanoparticles: a robust drug delivery platform. ACS Nano. 2008 Aug; 2(8):1696-702. PMID: 19206374.
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    40. Alexis F, Rhee JW, Richie JP, Radovic-Moreno AF, Langer R, Farokhzad OC. New frontiers in nanotechnology for cancer treatment. Urol Oncol. 2008 Jan-Feb; 26(1):74-85. PMID: 18190835.
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    41. Zhang L, Radovic-Moreno AF, Alexis F, Gu FX, Basto PA, Bagalkot V, Jon S, Langer RS, Farokhzad OC. Co-delivery of hydrophobic and hydrophilic drugs from nanoparticle-aptamer bioconjugates. ChemMedChem. 2007 Sep; 2(9):1268-71. PMID: 17600796.
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    42. Alexis F, Zeng J, Shu W. PEI Nanoparticles for Targeted Gene Delivery. CSH Protoc. 2006 Jun 01; 2006(1). PMID: 22485782.
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    43. Alexis F, Venkatraman SS, Rath SK, Boey F. In vitro study of release mechanisms of paclitaxel and rapamycin from drug-incorporated biodegradable stent matrices. J Control Release. 2004 Jul 23; 98(1):67-74. PMID: 15245890.
      View in: PubMed
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