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Dev Priya Arya

TitleProfessor
InstitutionClemson University
DepartmentDepartment of Chemistry
Address223 Hunter Hall
Clemson, South Carolina 29634
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Chamberlin J, Story S, Ranjan N, Chesser G, Arya DP. Gram-negative synergy and mechanism of action of alkynyl bisbenzimidazoles. Sci Rep. 2019 Oct 02; 9(1):14171. PMID: 31578425.
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    2. Ranjan N, Arya DP. A fluorescent aminosugar to rapidly screen and study RNA binders. Methods Enzymol. 2019; 623:291-314. PMID: 31239051.
      View in: PubMed
    3. Watkins D, Maiti K, Arya DP. Aminoglycoside Functionalization as a Tool for Targeting Nucleic Acids. Methods Mol Biol. 2019; 1973:147-162. PMID: 31016700.
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    4. Story S, Skriba MJ, Maiti K, Degtyareva NN, Green KD, Khodaverdian V, Oyelere AK, Garneau-Tsodikova S, Arya DP. Synthesis, antimicrobial activity, attenuation of aminoglycoside resistance in MRSA, and ribosomal A-site binding of pyrene-neomycin conjugates. Eur J Med Chem. 2019 Feb 01; 163:381-393. PMID: 30530174.
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    5. Ghosh A, Degyatoreva N, Kukielski C, Story S, Bhaduri S, Maiti K, Nahar S, Ray A, Arya DP, Maiti S. Targeting miRNA by tunable small molecule binders: peptidic aminosugar mediated interference in miR-21 biogenesis reverts epithelial to mesenchymal transition. Medchemcomm. 2018 Jul 01; 9(7):1147-1154. PMID: 30109002.
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    6. Bhaduri S, Ranjan N, Arya DP. An overview of recent advances in duplex DNA recognition by small molecules. Beilstein J Org Chem. 2018; 14:1051-1086. PMID: 29977379.
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    7. Thamban Chandrika N, Shrestha SK, Ranjan N, Sharma A, Arya DP, Garneau-Tsodikova S. New Application of Neomycin B-Bisbenzimidazole Hybrids as Antifungal Agents. ACS Infect Dis. 2018 02 09; 4(2):196-207. PMID: 29227087.
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    8. Ranjan N, Kellish P, King A, Arya DP. Impact of Linker Length and Composition on Fragment Binding and Cell Permeation: Story of a Bisbenzimidazole Dye Fragment. Biochemistry. 2017 Dec 12; 56(49):6434-6447. PMID: 29131946.
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    9. Gómez Ramos LM, Degtyareva NN, Kovacs NA, Holguin SY, Jiang L, Petrov AS, Biesiada M, Hu MY, Purzycka KJ, Arya DP, Williams LD. Eukaryotic Ribosomal Expansion Segments as Antimicrobial Targets. Biochemistry. 2017 10 10; 56(40):5288-5299. PMID: 28895721.
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    10. Kamphan A, Gong C, Maiti K, Sur S, Traiphol R, Arya DP. Utilization of chromic polydiacetylene assemblies as a platform to probe specific binding between drug and RNA. RSC Adv. 2017; 7(66):41435-41443. PMID: 29276583.
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    11. Ranjan N, Story S, Fulcrand G, Leng F, Ahmad M, King A, Sur S, Wang W, Tse-Dinh YC, Arya DP. Selective Inhibition of Escherichia coli RNA and DNA Topoisomerase I by Hoechst 33258 Derived Mono- and Bisbenzimidazoles. J Med Chem. 2017 06 22; 60(12):4904-4922. PMID: 28513176.
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    12. Degtyareva NN, Gong C, Story S, Levinson NS, Oyelere AK, Green KD, Garneau-Tsodikova S, Arya DP. Antimicrobial Activity, AME Resistance, and A-Site Binding Studies of Anthraquinone-Neomycin Conjugates. ACS Infect Dis. 2017 03 10; 3(3):206-215. PMID: 28103015.
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    13. Watkins D, Gong C, Kellish P, Arya DP. Probing A-form DNA: A fluorescent aminosugar probe and dual recognition by anthraquinone-neomycin conjugates. Bioorg Med Chem. 2017 02 15; 25(4):1309-1319. PMID: 28129992.
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    14. Ranjan N, Arya DP. Linker dependent intercalation of bisbenzimidazole-aminosugars in an RNA duplex; selectivity in RNA vs. DNA binding. Bioorg Med Chem Lett. 2016 12 15; 26(24):5989-5994. PMID: 27884695.
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    15. Kumar S, Ranjan N, Kellish P, Gong C, Watkins D, Arya DP. Multivalency in the recognition and antagonism of a HIV TAR RNA-TAT assembly using an aminoglycoside benzimidazole scaffold. Org Biomol Chem. 2016 Feb 14; 14(6):2052-6. PMID: 26765486.
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    16. Watkins D, Jiang L, Nahar S, Maiti S, Arya DP. A pH Sensitive High-Throughput Assay for miRNA Binding of a Peptide-Aminoglycoside (PA) Library. PLoS One. 2015; 10(12):e0144251. PMID: 26656788.
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    17. Jin Y, Watkins D, Degtyareva NN, Green KD, Spano MN, Garneau-Tsodikova S, Arya DP. Arginine-linked neomycin B dimers: synthesis, rRNA binding, and resistance enzyme activity. Medchemcomm. 2016 Jan 01; 7(1):164-169. PMID: 26811742.
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    18. Nahar S, Ranjan N, Ray A, Arya DP, Maiti S. Potent inhibition of miR-27a by neomycin-bisbenzimidazole conjugates. Chem Sci. 2015 Oct 01; 6(10):5837-5846. PMID: 29861909.
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    19. Kumar S, Spano MN, Arya DP. Influence of linker length in shape recognition of B* DNA by dimeric aminoglycosides. Bioorg Med Chem. 2015 Jul 01; 23(13):3105-9. PMID: 26025072.
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    20. Watkins D, Kumar S, Green KD, Arya DP, Garneau-Tsodikova S. Influence of linker length and composition on enzymatic activity and ribosomal binding of neomycin dimers. Antimicrob Agents Chemother. 2015 Jul; 59(7):3899-905. PMID: 25896697.
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    21. Jiang L, Watkins D, Jin Y, Gong C, King A, Washington AZ, Green KD, Garneau-Tsodikova S, Oyelere AK, Arya DP. Rapid synthesis, RNA binding, and antibacterial screening of a peptidic-aminosugar (PA) library. ACS Chem Biol. 2015 May 15; 10(5):1278-89. PMID: 25706406.
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    22. Woo CM, Ranjan N, Arya DP, Herzon SB. Analysis of diazofluorene DNA binding and damaging activity: DNA cleavage by a synthetic monomeric diazofluorene. Angew Chem Int Ed Engl. 2014 Aug 25; 53(35):9325-8. PMID: 25044348.
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    23. Kumar S, Newby Spano M, Arya DP. Shape readout of AT-rich DNA by carbohydrates. Biopolymers. 2014 Jul; 101(7):720-32. PMID: 24281844.
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    24. Ranjan N, Fulcrand G, King A, Brown J, Jiang X, Leng F, Arya DP. Selective Inhibition of Bacterial Topoisomerase I by alkynyl-bisbenzimidazoles. Medchemcomm. 2014 Jun 01; 5(6):816-825. PMID: 25083189.
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    25. Kellish PC, Kumar S, Mack TS, Spano MN, Hennig M, Arya DP. Multivalent Amino Sugars to Recognize Different TAR RNA Conformations. Medchemcomm. 2014 Aug 01; 5(8):1235-1246. PMID: 27076899.
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    26. Willis B, Arya DP. Recognition of RNA duplex by a neomycin-Hoechst 33258 conjugate. Bioorg Med Chem. 2014 Apr 01; 22(7):2327-32. PMID: 24630691.
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    27. Ranjan N, Arya DP. Targeting C-myc G-quadruplex: dual recognition by aminosugar-bisbenzimidazoles with varying linker lengths. Molecules. 2013 Nov 18; 18(11):14228-40. PMID: 24252993.
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    28. Watkins D, Ranjan N, Kumar S, Gong C, Arya DP. An assay for human telomeric G-quadruplex DNA binding drugs. Bioorg Med Chem Lett. 2013 Dec 15; 23(24):6695-9. PMID: 24246738.
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    29. Ranjan N, Kumar S, Watkins D, Wang D, Appella DH, Arya DP. Recognition of HIV-TAR RNA using neomycin-benzimidazole conjugates. Bioorg Med Chem Lett. 2013 Oct 15; 23(20):5689-93. PMID: 24012122.
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    30. King A, Watkins D, Kumar S, Ranjan N, Gong C, Whitlock J, Arya DP. Characterization of ribosomal binding and antibacterial activities using two orthogonal high-throughput screens. Antimicrob Agents Chemother. 2013 Oct; 57(10):4717-26. PMID: 23856777.
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    31. Ranjan N, Davis E, Xue L, Arya DP. Dual recognition of the human telomeric G-quadruplex by a neomycin-anthraquinone conjugate. Chem Commun (Camb). 2013 Jun 28; 49(51):5796-8. PMID: 23698792.
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    32. Watkins D, Norris FA, Kumar S, Arya DP. A fluorescence-based screen for ribosome binding antibiotics. Anal Biochem. 2013 Mar 15; 434(2):300-7. PMID: 23262284.
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    33. Charles I, Davis E, Arya DP. Efficient stabilization of phosphodiester (PO), phosphorothioate (PS), and 2'-O-methoxy (2'-OMe) DNA·RNA hybrid duplexes by amino sugars. Biochemistry. 2012 Jul 10; 51(27):5496-505. PMID: 22639785.
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    34. Kumar S, Kellish P, Robinson WE, Wang D, Appella DH, Arya DP. Click dimers to target HIV TAR RNA conformation. Biochemistry. 2012 Mar 20; 51(11):2331-47. PMID: 22339203.
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    35. Hamilton PL, Arya DP. Natural product DNA major groove binders. Nat Prod Rep. 2012 Feb; 29(2):134-43. PMID: 22183179.
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    36. Xi H, Davis E, Ranjan N, Xue L, Hyde-Volpe D, Arya DP. Thermodynamics of nucleic acid "shape readout" by an aminosugar. Biochemistry. 2011 Oct 25; 50(42):9088-113. PMID: 21863895.
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    37. Kumar S, Arya DP. Recognition of HIV TAR RNA by triazole linked neomycin dimers. Bioorg Med Chem Lett. 2011 Aug 15; 21(16):4788-92. PMID: 21757341.
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    38. Kumar S, Xue L, Arya DP. Neomycin-neomycin dimer: an all-carbohydrate scaffold with high affinity for AT-rich DNA duplexes. J Am Chem Soc. 2011 May 18; 133(19):7361-75. PMID: 21524066.
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    39. Xue L, Ranjan N, Arya DP. Synthesis and spectroscopic studies of the aminoglycoside (neomycin)--perylene conjugate binding to human telomeric DNA. Biochemistry. 2011 Apr 12; 50(14):2838-49. PMID: 21329360.
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    40. Arya DP. New approaches toward recognition of nucleic acid triple helices. Acc Chem Res. 2011 Feb 15; 44(2):134-46. PMID: 21073199.
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    41. Ranjan N, Andreasen KF, Kumar S, Hyde-Volpe D, Arya DP. Aminoglycoside binding to Oxytricha nova telomeric DNA. Biochemistry. 2010 Nov 16; 49(45):9891-903. PMID: 20886815.
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    42. Xue L, Xi H, Kumar S, Gray D, Davis E, Hamilton P, Skriba M, Arya DP. Probing the recognition surface of a DNA triplex: binding studies with intercalator-neomycin conjugates. Biochemistry. 2010 Jul 06; 49(26):5540-52. PMID: 20499878.
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    43. Xi H, Kumar S, Dosen-Micovic L, Arya DP. Calorimetric and spectroscopic studies of aminoglycoside binding to AT-rich DNA triple helices. Biochimie. 2010 May; 92(5):514-29. PMID: 20167243.
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    44. Willis B, Arya DP. Triple recognition of B-DNA by a neomycin-Hoechst 33258-pyrene conjugate. Biochemistry. 2010 Jan 26; 49(3):452-69. PMID: 20000367.
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    45. Willis B, Arya DP. Triple recognition of B-DNA. Bioorg Med Chem Lett. 2009 Sep 01; 19(17):4974-9. PMID: 19651510.
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    46. Xi H, Gray D, Kumar S, Arya DP. Molecular recognition of single-stranded RNA: neomycin binding to poly(A). FEBS Lett. 2009 Jul 07; 583(13):2269-75. PMID: 19520078.
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    47. Shaw NN, Xi H, Arya DP. Molecular recognition of a DNA:RNA hybrid: sub-nanomolar binding by a neomycin-methidium conjugate. Bioorg Med Chem Lett. 2008 Jul 15; 18(14):4142-5. PMID: 18573660.
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    48. Shaw NN, Arya DP. Recognition of the unique structure of DNA:RNA hybrids. Biochimie. 2008 Jul; 90(7):1026-39. PMID: 18486626.
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    49. Charles I, Xi H, Arya DP. Sequence-specific targeting of RNA with an oligonucleotide-neomycin conjugate. Bioconjug Chem. 2007 Jan-Feb; 18(1):160-9. PMID: 17226969.
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    50. Willis B, Arya DP. Recognition of B-DNA by neomycin--Hoechst 33258 conjugates. Biochemistry. 2006 Aug 29; 45(34):10217-32. PMID: 16922497.
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    51. Willis B, Arya DP. An expanding view of aminoglycoside-nucleic acid recognition. Adv Carbohydr Chem Biochem. 2006; 60:251-302. PMID: 16750445.
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    52. Napoli S, Carbone GM, Catapano CV, Shaw N, Arya DP. Neomycin improves cationic lipid-mediated transfection of DNA in human cells. Bioorg Med Chem Lett. 2005 Jul 15; 15(14):3467-9. PMID: 15950473.
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    53. Xi H, Arya DP. Recognition of triple helical nucleic acids by aminoglycosides. Curr Med Chem Anticancer Agents. 2005 Jul; 5(4):327-38. PMID: 16101485.
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    54. Arya DP, Coffee RL, Xue L. From triplex to B-form duplex stabilization: reversal of target selectivity by aminoglycoside dimers. Bioorg Med Chem Lett. 2004 Sep 20; 14(18):4643-6. PMID: 15324880.
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    55. Arya DP, Willis B. Reaching into the major groove of B-DNA: synthesis and nucleic acid binding of a neomycin-hoechst 33258 conjugate. J Am Chem Soc. 2003 Oct 15; 125(41):12398-9. PMID: 14531669.
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    56. Arya DP, Xue L, Willis B. Aminoglycoside (neomycin) preference is for A-form nucleic acids, not just RNA: results from a competition dialysis study. J Am Chem Soc. 2003 Aug 27; 125(34):10148-9. PMID: 12926918.
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    57. Arya DP, Xue L, Tennant P. Combining the best in triplex recognition: synthesis and nucleic acid binding of a BQQ-neomycin conjugate. J Am Chem Soc. 2003 Jul 09; 125(27):8070-1. PMID: 12837054.
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    58. Arya DP, Micovic L, Charles I, Coffee RL, Willis B, Xue L. Neomycin binding to Watson-Hoogsteen (W-H) DNA triplex groove: a model. J Am Chem Soc. 2003 Apr 02; 125(13):3733-44. PMID: 12656603.
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    59. Davis WC, Venzie JL, Willis B, Coffee RL, Arya DP, Marcus RK. Particle beam glow discharge mass spectrometry: spectral characteristics of nucleobases. Rapid Commun Mass Spectrom. 2003; 17(15):1749-58. PMID: 12872280.
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    60. Charles I, Xue L, Arya DP. Synthesis of aminoglycoside-DNA conjugates. Bioorg Med Chem Lett. 2002 May 06; 12(9):1259-62. PMID: 11965366.
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    61. Xue L, Charles I, Arya DP. Pyrene-neomycin conjugate: dual recognition of a DNA triple helix. Chem Commun (Camb). 2002 Jan 07; (1):70-1. PMID: 12120315.
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    62. Arya DP, Coffee RL, Charles I. Neomycin-induced hybrid triplex formation. J Am Chem Soc. 2001 Nov 07; 123(44):11093-4. PMID: 11686727.
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    63. Arya DP, Coffee RL, Willis B, Abramovitch AI. Aminoglycoside-nucleic acid interactions: remarkable stabilization of DNA and RNA triple helices by neomycin. J Am Chem Soc. 2001 Jun 13; 123(23):5385-95. PMID: 11389616.
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    64. Arya DP, Coffee RL. DNA triple helix stabilization by aminoglycoside antibiotics. Bioorg Med Chem Lett. 2000 Sep 04; 10(17):1897-9. PMID: 10987412.
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    65. Arya DP, Bruice TC. Solid-phase synthesis of oligomeric deoxynucleic-thiourea (DNT) and deoxynucleic S-methylthiourea (DNmt): a neutral/polycationic analogue of DNA. Bioorg Med Chem Lett. 2000 Apr 17; 10(8):691-3. PMID: 10782665.
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    66. Arya DP, Bruice TC. Triple-helix formation of DNA oligomers with methylthiourea-linked nucleosides (DNmt): a kinetic and thermodynamic analysis. Proc Natl Acad Sci U S A. 1999 Apr 13; 96(8):4384-9. PMID: 10200271.
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