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Institution

Zhi Zhong

Title
InstitutionMedical University of South Carolina
DepartmentCOP Drug Discovery and Biomedical Sciences - MUSC Campus
AddressP.O. Box MSC140
QE219
43 Sabin St.
Phone843-792-2163
Fax843-792-1617
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Krishnasamy Y, Gooz M, Li L, Lemasters JJ, Zhong Z. Role of mitochondrial depolarization and disrupted mitochondrial homeostasis in non-alcoholic steatohepatitis and fibrosis in mice. Int J Physiol Pathophysiol Pharmacol. 2019; 11(5):190-204. PMID: 31777643.
      View in: PubMed
    2. Wimborne HJ, Takemoto K, Woster PM, Rockey DC, Lemasters JJ, Zhong Z. Aldehyde dehydrogenase-2 activation by Alda-1 decreases necrosis and fibrosis after bile duct ligation in mice. Free Radic Biol Med. 2019 Dec; 145:136-145. PMID: 31557514.
      View in: PubMed
    3. Lemasters JJ, Zhong Z. Mitophagy in hepatocytes: Types, initiators and role in adaptive ethanol metabolism?. Liver Res. 2018 Sep; 2(3):125-132. PMID: 31157120.
      View in: PubMed
    4. Zhong Z, Lemasters JJ. A Unifying Hypothesis Linking Hepatic Adaptations for Ethanol Metabolism to the Proinflammatory and Profibrotic Events of Alcoholic Liver Disease. Alcohol Clin Exp Res. 2018 11; 42(11):2072-2089. PMID: 30132924.
      View in: PubMed
    5. Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Zhong Z. Ischemic preconditioning attenuates acute lung injury after partial liver transplantation. Int J Physiol Pathophysiol Pharmacol. 2018; 10(2):83-94. PMID: 29755641.
      View in: PubMed
    6. Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Zhong Z. 8-pCPT-cGMP prevents mitochondrial depolarization and improves the outcome of steatotic partial liver transplantation. Int J Physiol Pathophysiol Pharmacol. 2017; 9(3):69-83. PMID: 28694919.
      View in: PubMed
    7. Krishnasamy Y, Ramshesh VK, Gooz M, Schnellmann RG, Lemasters JJ, Zhong Z. Ethanol and High Cholesterol Diet Causes Severe Steatohepatitis and Early Liver Fibrosis in Mice. PLoS One. 2016; 11(9):e0163342. PMID: 27676640.
      View in: PubMed
    8. Rehman H, Liu Q, Krishnasamy Y, Shi Z, Ramshesh VK, Haque K, Schnellmann RG, Murphy MP, Lemasters JJ, Rockey DC, Zhong Z. The mitochondria-targeted antioxidant MitoQ attenuates liver fibrosis in mice. Int J Physiol Pathophysiol Pharmacol. 2016; 8(1):14-27. PMID: 27186319.
      View in: PubMed
    9. Liu Q, Krishnasamy Y, Rehman H, Lemasters JJ, Schnellmann RG, Zhong Z. Disrupted Renal Mitochondrial Homeostasis after Liver Transplantation in Rats. PLoS One. 2015; 10(10):e0140906. PMID: 26480480.
      View in: PubMed
    10. Liu Q, Rehman H, Krishnasamy Y, Schnellmann RG, Lemasters JJ, Zhong Z. Improvement of liver injury and survival by JNK2 and iNOS deficiency in liver transplants from cardiac death mice. J Hepatol. 2015 Jul; 63(1):68-74. PMID: 25703084.
      View in: PubMed
    11. Whitaker RM, Korrapati MC, Stallons LJ, Jesinkey SR, Arthur JM, Beeson CC, Zhong Z, Schnellmann RG. Urinary ATP Synthase Subunit ß Is a Novel Biomarker of Renal Mitochondrial Dysfunction in Acute Kidney Injury. Toxicol Sci. 2015 May; 145(1):108-17. PMID: 25666834.
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    12. Kholmukhamedov A, Czerny C, Hu J, Schwartz J, Zhong Z, Lemasters JJ. Minocycline and doxycycline, but not tetracycline, mitigate liver and kidney injury after hemorrhagic shock/resuscitation. Shock. 2014 Sep; 42(3):256-63. PMID: 24978888.
      View in: PubMed
    13. Marshall KM, He S, Zhong Z, Atkinson C, Tomlinson S. Dissecting the complement pathway in hepatic injury and regeneration with a novel protective strategy. J Exp Med. 2014 Aug 25; 211(9):1793-805. PMID: 25113972.
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    14. Zhong Z, Ramshesh VK, Rehman H, Liu Q, Theruvath TP, Krishnasamy Y, Lemasters JJ. Acute ethanol causes hepatic mitochondrial depolarization in mice: role of ethanol metabolism. PLoS One. 2014; 9(3):e91308. PMID: 24618581.
      View in: PubMed
    15. Rehman H, Krishnasamy Y, Haque K, Thurman RG, Lemasters JJ, Schnellmann RG, Zhong Z. Green tea polyphenols stimulate mitochondrial biogenesis and improve renal function after chronic cyclosporin a treatment in rats. PLoS One. 2014; 8(6):e65029. PMID: 23755172.
      View in: PubMed
    16. He S, Rehman H, Shi Y, Krishnasamy Y, Lemasters JJ, Schnellmann RG, Zhong Z. Suramin decreases injury and improves regeneration of ethanol-induced steatotic partial liver grafts. J Pharmacol Exp Ther. 2013 Feb; 344(2):417-25. PMID: 23161217.
      View in: PubMed
    17. Liu Q, Rehman H, Shi Y, Krishnasamy Y, Lemasters JJ, Smith CD, Zhong Z. Inhibition of sphingosine kinase-2 suppresses inflammation and attenuates graft injury after liver transplantation in rats. PLoS One. 2012; 7(7):e41834. PMID: 22848628.
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    18. Czerny C, Theruvath TP, Maldonado EN, Lehnert M, Marzi I, Zhong Z, Lemasters JJ. C-Jun N-Terminal Kinase 2 Promotes Liver Injury via the Mitochondrial Permeability Transition after Hemorrhage and Resuscitation. HPB Surg. 2012; 2012:641982. PMID: 22791932.
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    19. Theruvath TP, Ramshesh VK, Zhong Z, Currin RT, Karrasch T, Lemasters JJ. Icam-1 upregulation in ethanol-induced Fatty murine livers promotes injury and sinusoidal leukocyte adherence after transplantation. HPB Surg. 2012; 2012:480893. PMID: 22778492.
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    20. Czerny C, Kholmukhamedov A, Theruvath TP, Maldonado EN, Ramshesh VK, Lehnert M, Marzi I, Zhong Z, Lemasters JJ. Minocycline decreases liver injury after hemorrhagic shock and resuscitation in mice. HPB Surg. 2012; 2012:259512. PMID: 22719175.
      View in: PubMed
    21. Liu Q, Rehman H, Harley RA, Lemasters JJ, Zhong Z. Small-for-Size Liver Transplantation Increases Pulmonary Injury in Rats: Prevention by NIM811. HPB Surg. 2012; 2012:270372. PMID: 22675237.
      View in: PubMed
    22. Liu Q, Rehman H, Krishnasamy Y, Ramshesh VK, Theruvath TP, Chavin KD, Schnellmann RG, Lemasters JJ, Zhong Z. Role of inducible nitric oxide synthase in mitochondrial depolarization and graft injury after transplantation of fatty livers. Free Radic Biol Med. 2012 Jul 15; 53(2):250-9. PMID: 22609250.
      View in: PubMed
    23. Lemasters JJ, Holmuhamedov EL, Czerny C, Zhong Z, Maldonado EN. Regulation of mitochondrial function by voltage dependent anion channels in ethanol metabolism and the Warburg effect. Biochim Biophys Acta. 2012 Jun; 1818(6):1536-44. PMID: 22172804.
      View in: PubMed
    24. Shi Y, Rehman H, Ramshesh VK, Schwartz J, Liu Q, Krishnasamy Y, Zhang X, Lemasters JJ, Smith CD, Zhong Z. Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia-reperfusion. J Hepatol. 2012 Jan; 56(1):137-45. PMID: 21756852.
      View in: PubMed
    25. Rehman H, Sun J, Shi Y, Ramshesh VK, Liu Q, Currin RT, Lemasters JJ, Zhong Z. NIM811 prevents mitochondrial dysfunction, attenuates liver injury, and stimulates liver regeneration after massive hepatectomy. Transplantation. 2011 Feb 27; 91(4):406-12. PMID: 21131897.
      View in: PubMed
    26. Shi Y, Rehman H, Wright GL, Zhong Z. Inhibition of inducible nitric oxide synthase prevents graft injury after transplantation of livers from rats after cardiac death. Liver Transpl. 2010 Nov; 16(11):1267-77. PMID: 21031542.
      View in: PubMed
    27. Lehnert M, Lind H, Zhong Z, Schoonhoven R, Marzi I, Lemasters JJ. Polyphenols of Camellia sinenesis decrease mortality, hepatic injury and generation of cytokines and reactive oxygen and nitrogen species after hemorrhage/resuscitation in rats. BMC Complement Altern Med. 2010 Aug 24; 10:46. PMID: 20735845.
      View in: PubMed
    28. He S, Rehman H, Wright GL, Zhong Z. Inhibition of inducible nitric oxide synthase prevents mitochondrial damage and improves survival of steatotic partial liver grafts. Transplantation. 2010 Feb 15; 89(3):291-8. PMID: 20145519.
      View in: PubMed
    29. Zhong Z, Tsukada S, Rehman H, Parsons CJ, Theruvath TP, Rippe RA, Brenner DA, Lemasters JJ. Inhibition of transforming growth factor-beta/Smad signaling improves regeneration of small-for-size rat liver grafts. Liver Transpl. 2010 Feb; 16(2):181-90. PMID: 20104486.
      View in: PubMed
    30. Lemasters JJ, Theruvath TP, Zhong Z, Nieminen AL. Mitochondrial calcium and the permeability transition in cell death. Biochim Biophys Acta. 2009 Nov; 1787(11):1395-401. PMID: 19576166.
      View in: PubMed
    31. Rehman H, Ramshesh VK, Theruvath TP, Kim I, Currin RT, Giri S, Lemasters JJ, Zhong Z. NIM811 (N-methyl-4-isoleucine cyclosporine), a mitochondrial permeability transition inhibitor, attenuates cholestatic liver injury but not fibrosis in mice. J Pharmacol Exp Ther. 2008 Dec; 327(3):699-706. PMID: 18801946.
      View in: PubMed
    32. Zhong Z, Ramshesh VK, Rehman H, Currin RT, Sridharan V, Theruvath TP, Kim I, Wright GL, Lemasters JJ. Activation of the oxygen-sensing signal cascade prevents mitochondrial injury after mouse liver ischemia-reperfusion. Am J Physiol Gastrointest Liver Physiol. 2008 Oct; 295(4):G823-32. PMID: 18772364.
      View in: PubMed
    33. Rehman H, Connor HD, Ramshesh VK, Theruvath TP, Mason RP, Wright GL, Lemasters JJ, Zhong Z. Ischemic preconditioning prevents free radical production and mitochondrial depolarization in small-for-size rat liver grafts. Transplantation. 2008 May 15; 85(9):1322-31. PMID: 18475191.
      View in: PubMed
    34. Theruvath TP, Zhong Z, Pediaditakis P, Ramshesh VK, Currin RT, Tikunov A, Holmuhamedov E, Lemasters JJ. Minocycline and N-methyl-4-isoleucine cyclosporin (NIM811) mitigate storage/reperfusion injury after rat liver transplantation through suppression of the mitochondrial permeability transition. Hepatology. 2008 Jan; 47(1):236-46. PMID: 18023036.
      View in: PubMed
    35. Zhong Z, Theruvath TP, Currin RT, Waldmeier PC, Lemasters JJ. NIM811, a mitochondrial permeability transition inhibitor, prevents mitochondrial depolarization in small-for-size rat liver grafts. Am J Transplant. 2007 May; 7(5):1103-11. PMID: 17456198.
      View in: PubMed
    36. Zhong Z, Connor HD, Li X, Mason RP, Forman DT, Lemasters JJ, Thurman RG. Reduction of ciclosporin and tacrolimus nephrotoxicity by plant polyphenols. J Pharm Pharmacol. 2006 Nov; 58(11):1533-43. PMID: 17132217.
      View in: PubMed
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