Keywords
Last Name
Institution

Yefim Manevich

Title
InstitutionMedical University of South Carolina
DepartmentCell and Molecular Pharmacology and Experimental Therapeutics
AddressP.O. Box 509
DD410
70 President St.
Phone843-876-2388
Fax843-792-9588
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Zhang L, Zhang J, Ye Z, Manevich Y, Townsend DM, Marshall DT, Tew KD. S-Glutathionylated Serine Proteinase Inhibitors as Biomarkers for Radiation Exposure in Prostate Cancer Patients. Sci Rep. 2019 Sep 24; 9(1):13792. PMID: 31551460.
      View in: PubMed
    2. Zhang L, Zhang J, Ye Z, Manevich Y, Ball LE, Bethard JR, Jiang YL, Broome AM, Dalton AC, Wang GY, Townsend DM, Tew KD. Isoflavone ME-344 Disrupts Redox Homeostasis and Mitochondrial Function by Targeting Heme Oxygenase 1. Cancer Res. 2019 Aug 15; 79(16):4072-4085. PMID: 31227482.
      View in: PubMed
    3. Robinson RM, Reyes L, Duncan RM, Bian H, Reitz AB, Manevich Y, McClure JJ, Champion MM, Chou CJ, Sharik ME, Chesi M, Bergsagel PL, Dolloff NG. Inhibitors of the protein disulfide isomerase family for the treatment of multiple myeloma. Leukemia. 2019 04; 33(4):1011-1022. PMID: 30315229.
      View in: PubMed
    4. Zhang J, Ye ZW, Chen W, Manevich Y, Mehrotra S, Ball L, Janssen-Heininger Y, Tew KD, Townsend DM. S-Glutathionylation of estrogen receptor a affects dendritic cell function. J Biol Chem. 2018 03 23; 293(12):4366-4380. PMID: 29374060.
      View in: PubMed
    5. Thompson RM, Dytfeld D, Reyes L, Robinson RM, Smith B, Manevich Y, Jakubowiak A, Komarnicki M, Przybylowicz-Chalecka A, Szczepaniak T, Mitra AK, Van Ness BG, Luczak M, Dolloff NG. Glutaminase inhibitor CB-839 synergizes with carfilzomib in resistant multiple myeloma cells. Oncotarget. 2017 May 30; 8(22):35863-35876. PMID: 28415782.
      View in: PubMed
    6. Manevich Y, Reyes L, Britten CD, Townsend DM, Tew KD. Redox Signaling and Bioenergetics Influence Lung Cancer Cell Line Sensitivity to the Isoflavone ME-344. J Pharmacol Exp Ther. 2016 08; 358(2):199-208. PMID: 27255112.
      View in: PubMed
    7. Ye ZW, Zhang J, Ancrum T, Manevich Y, Townsend DM, Tew KD. Glutathione S-Transferase P-Mediated Protein S-Glutathionylation of Resident Endoplasmic Reticulum Proteins Influences Sensitivity to Drug-Induced Unfolded Protein Response. Antioxid Redox Signal. 2017 02 20; 26(6):247-261. PMID: 26838680.
      View in: PubMed
    8. Zhang J, Ye ZW, Gao P, Reyes L, Jones EE, Branham-O'Connor M, Blumer JB, Drake RR, Manevich Y, Townsend DM, Tew KD. Glutathione S-transferase P influences redox and migration pathways in bone marrow. PLoS One. 2014; 9(9):e107478. PMID: 25216273.
      View in: PubMed
    9. Qanungo S, Uys JD, Manevich Y, Distler AM, Shaner B, Hill EG, Mieyal JJ, Lemasters JJ, Townsend DM, Nieminen AL. N-acetyl-L-cysteine sensitizes pancreatic cancers to gemcitabine by targeting the NF?B pathway. Biomed Pharmacother. 2014 Sep; 68(7):855-64. PMID: 25257100.
      View in: PubMed
    10. Manevich Y, Hutchens S, Halushka PV, Tew KD, Townsend DM, Jauch EC, Borg K. Peroxiredoxin VI oxidation in cerebrospinal fluid correlates with traumatic brain injury outcome. Free Radic Biol Med. 2014 Jul; 72:210-21. PMID: 24726861.
      View in: PubMed
    11. Zhang J, Grek C, Ye ZW, Manevich Y, Tew KD, Townsend DM. Pleiotropic functions of glutathione S-transferase P. Adv Cancer Res. 2014; 122:143-75. PMID: 24974181.
      View in: PubMed
    12. Grek CL, Zhang J, Manevich Y, Townsend DM, Tew KD. Causes and consequences of cysteine S-glutathionylation. J Biol Chem. 2013 Sep 13; 288(37):26497-504. PMID: 23861399.
      View in: PubMed
    13. Maldonado EN, Sheldon KL, DeHart DN, Patnaik J, Manevich Y, Townsend DM, Bezrukov SM, Rostovtseva TK, Lemasters JJ. Voltage-dependent anion channels modulate mitochondrial metabolism in cancer cells: regulation by free tubulin and erastin. J Biol Chem. 2013 Apr 26; 288(17):11920-9. PMID: 23471966.
      View in: PubMed
    14. Turner-Ivey B, Manevich Y, Schulte J, Kistner-Griffin E, Jezierska-Drutel A, Liu Y, Neumann CA. Role for Prdx1 as a specific sensor in redox-regulated senescence in breast cancer. Oncogene. 2013 Nov 07; 32(45):5302-14. PMID: 23334324.
      View in: PubMed
    15. Manevich Y, Hutchens S, Tew KD, Townsend DM. Allelic variants of glutathione S-transferase P1-1 differentially mediate the peroxidase function of peroxiredoxin VI and alter membrane lipid peroxidation. Free Radic Biol Med. 2013 Jan; 54:62-70. PMID: 23142420.
      View in: PubMed
    16. Bowers RR, Manevich Y, Townsend DM, Tew KD. Sulfiredoxin redox-sensitive interaction with S100A4 and non-muscle myosin IIA regulates cancer cell motility. Biochemistry. 2012 Oct 02; 51(39):7740-54. PMID: 22934964.
      View in: PubMed
    17. Xiong Y, Manevich Y, Tew KD, Townsend DM. S-Glutathionylation of Protein Disulfide Isomerase Regulates Estrogen Receptor a Stability and Function. Int J Cell Biol. 2012; 2012:273549. PMID: 22654912.
      View in: PubMed
    18. Grek CL, Townsend DM, Uys JD, Manevich Y, Coker WJ, Pazoles CJ, Tew KD. S-glutathionylated serine proteinase inhibitors as plasma biomarkers in assessing response to redox-modulating drugs. Cancer Res. 2012 May 01; 72(9):2383-93. PMID: 22406622.
      View in: PubMed
    19. Senkal CE, Ponnusamy S, Manevich Y, Meyers-Needham M, Saddoughi SA, Mukhopadyay A, Dent P, Bielawski J, Ogretmen B. Alteration of ceramide synthase 6/C16-ceramide induces activating transcription factor 6-mediated endoplasmic reticulum (ER) stress and apoptosis via perturbation of cellular Ca2+ and ER/Golgi membrane network. J Biol Chem. 2011 Dec 09; 286(49):42446-58. PMID: 22013072.
      View in: PubMed
    20. Uys JD, Knackstedt L, Hurt P, Tew KD, Manevich Y, Hutchens S, Townsend DM, Kalivas PW. Cocaine-induced adaptations in cellular redox balance contributes to enduring behavioral plasticity. Neuropsychopharmacology. 2011 Nov; 36(12):2551-60. PMID: 21796101.
      View in: PubMed
    21. Tew KD, Manevich Y, Grek C, Xiong Y, Uys J, Townsend DM. The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer. Free Radic Biol Med. 2011 Jul 15; 51(2):299-313. PMID: 21558000.
      View in: PubMed
    22. Manevich Y, Townsend DM, Hutchens S, Tew KD. Diazeniumdiolate mediated nitrosative stress alters nitric oxide homeostasis through intracellular calcium and S-glutathionylation of nitric oxide synthetase. PLoS One. 2010 Nov 30; 5(11):e14151. PMID: 21152397.
      View in: PubMed
    23. Goetzl L, Manevich Y, Roedner C, Praktish A, Hebbar L, Townsend DM. Maternal and fetal oxidative stress and intrapartum term fever. Am J Obstet Gynecol. 2010 Apr; 202(4):363.e1-5. PMID: 20350644.
      View in: PubMed
    24. Hutchens S, Manevich Y, He L, Tew KD, Townsend DM. Cellular resistance to a nitric oxide releasing glutathione S-transferase P-activated prodrug, PABA/NO. Invest New Drugs. 2011 Oct; 29(5):719-29. PMID: 20232108.
      View in: PubMed
    25. Uys JD, Manevich Y, Devane LC, He L, Garret TE, Pazoles CJ, Tew KD, Townsend DM. Preclinical pharmacokinetic analysis of NOV-002, a glutathione disulfide mimetic. Biomed Pharmacother. 2010 Sep; 64(7):493-8. PMID: 20359856.
      View in: PubMed
    26. Neumann CA, Cao J, Manevich Y. Peroxiredoxin 1 and its role in cell signaling. Cell Cycle. 2009 Dec 15; 8(24):4072-8. PMID: 19923889.
      View in: PubMed
    27. Davis CW, Hawkins BJ, Ramasamy S, Irrinki KM, Cameron BA, Islam K, Daswani VP, Doonan PJ, Manevich Y, Madesh M. Nitration of the mitochondrial complex I subunit NDUFB8 elicits RIP1- and RIP3-mediated necrosis. Free Radic Biol Med. 2010 Jan 15; 48(2):306-17. PMID: 19897030.
      View in: PubMed
    28. Townsend DM, Manevich Y, He L, Xiong Y, Bowers RR, Hutchens S, Tew KD. Nitrosative stress-induced s-glutathionylation of protein disulfide isomerase leads to activation of the unfolded protein response. Cancer Res. 2009 Oct 01; 69(19):7626-34. PMID: 19773442.
      View in: PubMed
    29. Wu Y, Feinstein SI, Manevich Y, Chowdhury I, Pak JH, Kazi A, Dodia C, Speicher DW, Fisher AB. Mitogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A(2) activity. Biochem J. 2009 May 01; 419(3):669-79. PMID: 19140803.
      View in: PubMed
    30. Cao J, Schulte J, Knight A, Leslie NR, Zagozdzon A, Bronson R, Manevich Y, Beeson C, Neumann CA. Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity. EMBO J. 2009 May 20; 28(10):1505-17. PMID: 19369943.
      View in: PubMed
    31. Manevich Y, Shuvaeva T, Dodia C, Kazi A, Feinstein SI, Fisher AB. Binding of peroxiredoxin 6 to substrate determines differential phospholipid hydroperoxide peroxidase and phospholipase A(2) activities. Arch Biochem Biophys. 2009 May 15; 485(2):139-49. PMID: 19236840.
      View in: PubMed
    32. Townsend DM, Manevich Y, He L, Hutchens S, Pazoles CJ, Tew KD. Novel role for glutathione S-transferase pi. Regulator of protein S-Glutathionylation following oxidative and nitrosative stress. J Biol Chem. 2009 Jan 02; 284(1):436-45. PMID: 18990698.
      View in: PubMed
    33. Ralat LA, Misquitta SA, Manevich Y, Fisher AB, Colman RF. Characterization of the complex of glutathione S-transferase pi and 1-cysteine peroxiredoxin. Arch Biochem Biophys. 2008 Jun 01; 474(1):109-18. PMID: 18358825.
      View in: PubMed
    34. Manevich Y, Reddy KS, Shuvaeva T, Feinstein SI, Fisher AB. Structure and phospholipase function of peroxiredoxin 6: identification of the catalytic triad and its role in phospholipid substrate binding. J Lipid Res. 2007 Oct; 48(10):2306-18. PMID: 17652308.
      View in: PubMed
    35. Schremmer B, Manevich Y, Feinstein SI, Fisher AB. Peroxiredoxins in the lung with emphasis on peroxiredoxin VI. Subcell Biochem. 2007; 44:317-44. PMID: 18084901.
      View in: PubMed
    36. Fisher AB, Dodia C, Yu K, Manevich Y, Feinstein SI. Lung phospholipid metabolism in transgenic mice overexpressing peroxiredoxin 6. Biochim Biophys Acta. 2006 Jul; 1761(7):785-92. PMID: 16815092.
      View in: PubMed
    37. Ralat LA, Manevich Y, Fisher AB, Colman RF. Direct evidence for the formation of a complex between 1-cysteine peroxiredoxin and glutathione S-transferase pi with activity changes in both enzymes. Biochemistry. 2006 Jan 17; 45(2):360-72. PMID: 16401067.
      View in: PubMed
    38. Wang Y, Phelan SA, Manevich Y, Feinstein SI, Fisher AB. Transgenic mice overexpressing peroxiredoxin 6 show increased resistance to lung injury in hyperoxia. Am J Respir Cell Mol Biol. 2006 Apr; 34(4):481-6. PMID: 16399955.
      View in: PubMed
    39. Wang Y, Feinstein SI, Manevich Y, Ho YS, Fisher AB. Peroxiredoxin 6 gene-targeted mice show increased lung injury with paraquat-induced oxidative stress. Antioxid Redox Signal. 2006 Jan-Feb; 8(1-2):229-37. PMID: 16487056.
      View in: PubMed
    40. Wu YZ, Manevich Y, Baldwin JL, Dodia C, Yu K, Feinstein SI, Fisher AB. Interaction of surfactant protein A with peroxiredoxin 6 regulates phospholipase A2 activity. J Biol Chem. 2006 Mar 17; 281(11):7515-25. PMID: 16330552.
      View in: PubMed
    41. Milovanova T, Chatterjee S, Manevich Y, Kotelnikova I, Debolt K, Madesh M, Moore JS, Fisher AB. Lung endothelial cell proliferation with decreased shear stress is mediated by reactive oxygen species. Am J Physiol Cell Physiol. 2006 Jan; 290(1):C66-76. PMID: 16107509.
      View in: PubMed
    42. Manevich Y, Fisher AB. Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism. Free Radic Biol Med. 2005 Jun 01; 38(11):1422-32. PMID: 15890616.
      View in: PubMed
    43. Wang Y, Feinstein SI, Manevich Y, Ho YS, Fisher AB. Lung injury and mortality with hyperoxia are increased in peroxiredoxin 6 gene-targeted mice. Free Radic Biol Med. 2004 Dec 01; 37(11):1736-43. PMID: 15528033.
      View in: PubMed
    44. Wei Z, Manevich Y, Al-Mehdi AB, Chatterjee S, Fisher AB. Ca2+ flux through voltage-gated channels with flow cessation in pulmonary microvascular endothelial cells. Microcirculation. 2004 Sep; 11(6):517-26. PMID: 15371132.
      View in: PubMed
    45. Matsuzaki I, Chatterjee S, Debolt K, Manevich Y, Zhang Q, Fisher AB. Membrane depolarization and NADPH oxidase activation in aortic endothelium during ischemia reflect altered mechanotransduction. Am J Physiol Heart Circ Physiol. 2005 Jan; 288(1):H336-43. PMID: 15331375.
      View in: PubMed
    46. Wang Y, Manevich Y, Feinstein SI, Fisher AB. Adenovirus-mediated transfer of the 1-cys peroxiredoxin gene to mouse lung protects against hyperoxic injury. Am J Physiol Lung Cell Mol Physiol. 2004 Jun; 286(6):L1188-93. PMID: 15136296.
      View in: PubMed
    47. Milovanova T, Manevich Y, Haddad A, Chatterjee S, Moore JS, Fisher AB. Endothelial cell proliferation associated with abrupt reduction in shear stress is dependent on reactive oxygen species. Antioxid Redox Signal. 2004 Apr; 6(2):245-58. PMID: 15025926.
      View in: PubMed
    48. Mo Y, Feinstein SI, Manevich Y, Zhang Q, Lu L, Ho YS, Fisher AB. 1-Cys peroxiredoxin knock-out mice express mRNA but not protein for a highly related intronless gene. FEBS Lett. 2003 Dec 04; 555(2):192-8. PMID: 14644414.
      View in: PubMed
    49. Kim HS, Manevich Y, Feinstein SI, Pak JH, Ho YS, Fisher AB. Induction of 1-cys peroxiredoxin expression by oxidative stress in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2003 Aug; 285(2):L363-9. PMID: 12851211.
      View in: PubMed
    50. Matot I, Manevich Y, Al-Mehdi AB, Song C, Fisher AB. Fluorescence imaging of lipid peroxidation in isolated rat lungs during nonhypoxic lung ischemia. Free Radic Biol Med. 2003 Mar 15; 34(6):785-90. PMID: 12633755.
      View in: PubMed
    51. Fisher AB, Al-Mehdi AB, Wei Z, Song C, Manevich Y. Lung ischemia: endothelial cell signaling by reactive oxygen species. A progress report. Adv Exp Med Biol. 2003; 510:343-7. PMID: 12580451.
      View in: PubMed
    52. Pak JH, Manevich Y, Kim HS, Feinstein SI, Fisher AB. An antisense oligonucleotide to 1-cys peroxiredoxin causes lipid peroxidation and apoptosis in lung epithelial cells. J Biol Chem. 2002 Dec 20; 277(51):49927-34. PMID: 12372839.
      View in: PubMed
    53. Manevich Y, Sweitzer T, Pak JH, Feinstein SI, Muzykantov V, Fisher AB. 1-Cys peroxiredoxin overexpression protects cells against phospholipid peroxidation-mediated membrane damage. Proc Natl Acad Sci U S A. 2002 Sep 03; 99(18):11599-604. PMID: 12193653.
      View in: PubMed
    54. Thom SR, Bhopale V, Fisher D, Manevich Y, Huang PL, Buerk DG. Stimulation of nitric oxide synthase in cerebral cortex due to elevated partial pressures of oxygen: an oxidative stress response. J Neurobiol. 2002 May; 51(2):85-100. PMID: 11932951.
      View in: PubMed
    55. Fisher AB, Al-Mehdi AB, Manevich Y. Shear stress and endothelial cell activation. Crit Care Med. 2002 May; 30(5 Suppl):S192-7. PMID: 12004235.
      View in: PubMed
    Manevich's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description