Susan C Sonne

Title
InstitutionMedical University of South Carolina
DepartmentPsychiatry and Behavioral Sciences
AddressP.O. Box MSC 861
RN 190J
67 President St.
Phone843-792-5221
Fax843-792-3982
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    Dr. Sonne's primary research focus has been the pharmacotherapy of addiction and co-occurring disorders. She has served as the Principal Investigator of a number of federally funded trials for the treatment of substance use disorders, including trials for opioid dependence, stimulant dependence, and cigarette smoking. She has also received grant support from pharmaceutical companies to study the treatment of PTSD, PTSD and substance abuse, and comorbid alcohol dependence and anxiety or depression. Dr. Sonne serves as the national project director for a multi-site trial on the treatment of marijuana dependence. She is currently Chair of one of the Institutional Review Boards at MUSC and is also the Associate Director of the Regulatory Knowledge and Support Core of MUSC's South Carolina Clinical and Translational Research Institute.
    Collapse keywords
    marijuana dependence, smoking cessation, comorbidity, addiction treatment

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Trivedi MH, Walker R, Ling W, Dela Cruz A, Sharma G, Carmody T, Ghitza UE, Wahle A, Kim M, Shores-Wilson K, Sparenborg S, Coffin P, Schmitz J, Wiest K, Bart G, Sonne SC, Wakhlu S, Rush AJ, Nunes EV, Shoptaw S. Bupropion and Naltrexone in Methamphetamine Use Disorder. N Engl J Med. 2021 01 14; 384(2):140-153. PMID: 33497547.
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    2. Snider SH, Flume PA, Gentilin SL, Lesch WA, Sampson RR, Sonne SC. Overcoming non-compliance with clinical trial registration and results reporting: One Institution's approach. Contemp Clin Trials Commun. 2020 Jun; 18:100557. PMID: 32258818.
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    3. Tomko RL, Baker NL, Hood CO, Gilmore AK, McClure EA, Squeglia LM, McRae-Clark AL, Sonne SC, Gray KM. Depressive symptoms and cannabis use in a placebo-controlled trial of N-Acetylcysteine for adult cannabis use disorder. Psychopharmacology (Berl). 2020 Feb; 237(2):479-490. PMID: 31712969.
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    4. Montgomery L, McClure EA, Tomko RL, Sonne SC, Winhusen T, Terry GE, Grossman JT, Gray KM. Blunts versus joints: Cannabis use characteristics and consequences among treatment-seeking adults. Drug Alcohol Depend. 2019 05 01; 198:105-111. PMID: 30901744.
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    5. McClure EA, Baker NL, Sonne SC, Ghitza UE, Tomko RL, Montgomery L, Babalonis S, Terry GE, Gray KM. Tobacco use during cannabis cessation: Use patterns and impact on abstinence in a National Drug Abuse Treatment Clinical Trials Network study. Drug Alcohol Depend. 2018 11 01; 192:59-66. PMID: 30218864.
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    6. Bell L, Gentilin S, Sonne S, Mauney T, Flume P. Providing Restricted Access to an Electronic Medical Record for Research Monitoring. Clin Res (Alex). 2018; 32(3). PMID: 30613763.
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    7. Sonne S, Gentilin S, Sampson RR, Bell L, Mauney T, Young S, Bright K, Flume P. Regulatory Support Improves Subsequent IRB Approval Rates in Studies Initially Deemed Not Ready for Review: A CTSA Institution's Experience. J Empir Res Hum Res Ethics. 2018 04; 13(2):139-144. PMID: 29345179.
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    8. Sonne S, Gentilin S, Sampson RR, Bell L, Mauney T, Young S, Bright K, Flume P. Response to Commentary: Regulatory Support Improves Subsequent IRB Approval Rates in Studies Initially Deemed Not Ready for Review-A CTSA Institution's Experience. J Empir Res Hum Res Ethics. 2018 04; 13(2):148. PMID: 29345186.
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    9. Tomko RL, Baker NL, McClure EA, Sonne SC, McRae-Clark AL, Sherman BJ, Gray KM. Incremental validity of estimated cannabis grams as a predictor of problems and cannabinoid biomarkers: Evidence from a clinical trial. Drug Alcohol Depend. 2018 01 01; 182:1-7. PMID: 29112827.
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    10. Gray KM, Sonne SC, McClure EA, Ghitza UE, Matthews AG, McRae-Clark AL, Carroll KM, Potter JS, Wiest K, Mooney LJ, Hasson A, Walsh SL, Lofwall MR, Babalonis S, Lindblad RW, Sparenborg S, Wahle A, King JS, Baker NL, Tomko RL, Haynes LF, Vandrey RG, Levin FR. A randomized placebo-controlled trial of N-acetylcysteine for cannabis use disorder in adults. Drug Alcohol Depend. 2017 08 01; 177:249-257. PMID: 28623823.
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    11. McClure EA, King JS, Wahle A, Matthews AG, Sonne SC, Lofwall MR, McRae-Clark AL, Ghitza UE, Martinez M, Cloud K, Virk HS, Gray KM. Comparing adult cannabis treatment-seekers enrolled in a clinical trial with national samples of cannabis users in the United States. Drug Alcohol Depend. 2017 07 01; 176:14-20. PMID: 28511033.
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    12. Sherman BJ, McRae-Clark AL, Baker NL, Sonne SC, Killeen TK, Cloud K, Gray KM. Gender differences among treatment-seeking adults with cannabis use disorder: Clinical profiles of women and men enrolled in the achieving cannabis cessation-evaluating N-acetylcysteine treatment (ACCENT) study. Am J Addict. 2017 Mar; 26(2):136-144. PMID: 28152236.
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    13. Foster KT, Li N, McClure EA, Sonne SC, Gray KM. Gender Differences in Internalizing Symptoms and Suicide Risk Among Men and Women Seeking Treatment for Cannabis Use Disorder from Late Adolescence to Middle Adulthood. J Subst Abuse Treat. 2016 07; 66:16-22. PMID: 27211992.
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    14. McRae-Clark AL, Baker NL, Sonne SC, DeVane CL, Wagner A, Norton J. Concordance of Direct and Indirect Measures of Medication Adherence in A Treatment Trial for Cannabis Dependence. J Subst Abuse Treat. 2015 Oct; 57:70-4. PMID: 26028133.
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    15. McClure EA, Sonne SC, Winhusen T, Carroll KM, Ghitza UE, McRae-Clark AL, Matthews AG, Sharma G, Van Veldhuisen P, Vandrey RG, Levin FR, Weiss RD, Lindblad R, Allen C, Mooney LJ, Haynes L, Brigham GS, Sparenborg S, Hasson AL, Gray KM. Achieving cannabis cessation -- evaluating N-acetylcysteine treatment (ACCENT): design and implementation of a multi-site, randomized controlled study in the National Institute on Drug Abuse Clinical Trials Network. Contemp Clin Trials. 2014 Nov; 39(2):211-23. PMID: 25179587.
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    16. Winhusen TM, Brigham GS, Kropp F, Lindblad R, Gardin JG, Penn P, Hodgkins C, Kelly TM, Douaihy A, McCann M, Love LD, DeGravelles E, Bachrach K, Sonne SC, Hiott B, Haynes L, Sharma G, Lewis DF, VanVeldhuisen P, Theobald J, Ghitza U. A randomized trial of concurrent smoking-cessation and substance use disorder treatment in stimulant-dependent smokers. J Clin Psychiatry. 2014 Apr; 75(4):336-43. PMID: 24345356.
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    17. Winhusen TM, Adinoff B, Lewis DF, Brigham GS, Gardin JG, Sonne SC, Theobald J, Ghitza U. A tale of two stimulants: mentholated cigarettes may play a role in cocaine, but not methamphetamine, dependence. Drug Alcohol Depend. 2013 Dec 15; 133(3):845-51. PMID: 24075226.
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    18. Sonne SC, Andrews JO, Gentilin SM, Oppenheimer S, Obeid J, Brady K, Wolf S, Davis R, Magruder K. Development and pilot testing of a video-assisted informed consent process. Contemp Clin Trials. 2013 Sep; 36(1):25-31. PMID: 23747986.
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    19. Dreifuss JA, Griffin ML, Frost K, Fitzmaurice GM, Potter JS, Fiellin DA, Selzer J, Hatch-Maillette M, Sonne SC, Weiss RD. Patient characteristics associated with buprenorphine/naloxone treatment outcome for prescription opioid dependence: Results from a multisite study. Drug Alcohol Depend. 2013 Jul 01; 131(1-2):112-8. PMID: 23333292.
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    20. Weiss RD, Potter JS, Fiellin DA, Byrne M, Connery HS, Dickinson W, Gardin J, Griffin ML, Gourevitch MN, Haller DL, Hasson AL, Huang Z, Jacobs P, Kosinski AS, Lindblad R, McCance-Katz EF, Provost SE, Selzer J, Somoza EC, Sonne SC, Ling W. Adjunctive counseling during brief and extended buprenorphine-naloxone treatment for prescription opioid dependence: a 2-phase randomized controlled trial. Arch Gen Psychiatry. 2011 Dec; 68(12):1238-46. PMID: 22065255.
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    21. Winhusen TM, Lewis DF, Riggs PD, Davies RD, Adler LA, Sonne S, Somoza EC. Subjective effects, misuse, and adverse effects of osmotic-release methylphenidate treatment in adolescent substance abusers with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2011 Oct; 21(5):455-63. PMID: 22040190.
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    22. Reid MS, Jiang H, Fallon B, Sonne S, Rinaldi P, Turrigiano E, Arfken C, Robinson J, Rotrosen J, Nunes EV. Smoking cessation treatment among patients in community-based substance abuse rehabilitation programs: exploring predictors of outcome as clues toward treatment improvement. Am J Drug Alcohol Abuse. 2011 Sep; 37(5):472-8. PMID: 21854292.
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    23. Sonne SC, Nunes EV, Jiang H, Tyson C, Rotrosen J, Reid MS. The relationship between depression and smoking cessation outcomes in treatment-seeking substance abusers. Am J Addict. 2010 Mar-Apr; 19(2):111-8. PMID: 20163382.
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    24. Carter RE, Haynes LF, Back SE, Herrin AE, Brady KT, Leimberger JD, Sonne SC, Hubbard RL, Liepman MR. Improving the transition from residential to outpatient addiction treatment: gender differences in response to supportive telephone calls. Am J Drug Alcohol Abuse. 2008; 34(1):47-59. PMID: 18161643.
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    25. Reid MS, Fallon B, Sonne S, Flammino F, Nunes EV, Jiang H, Kourniotis E, Lima J, Brady R, Burgess C, Arfken C, Pihlgren E, Giordano L, Starosta A, Robinson J, Rotrosen J. Smoking cessation treatment in community-based substance abuse rehabilitation programs. J Subst Abuse Treat. 2008 Jul; 35(1):68-77. PMID: 17951021.
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    26. Reid MS, Fallon B, Sonne S, Nunes EV, Lima J, Jiang H, Tyson C, Hiott R, Arfken C, Bohs R, Orr D, Muir J, Pihlgren E, Loree A, Fuller BE, Giordano L, Robinson J, Rotrosen J. Implementation of a Smoking Cessation Treatment Study at Substance Abuse Rehabilitation Programs: Smoking Behavior and Treatment Feasibility Across Varied Community-based Outpatient Programs. J Addict Med. 2007 Sep; 1(3):154-60. PMID: 21768951.
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    27. Back SE, Brady KT, Sonne SC, Verduin ML. Symptom improvement in co-occurring PTSD and alcohol dependence. J Nerv Ment Dis. 2006 Sep; 194(9):690-6. PMID: 16971821.
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    28. Gelernter J, Panhuysen C, Wilcox M, Hesselbrock V, Rounsaville B, Poling J, Weiss R, Sonne S, Zhao H, Farrer L, Kranzler HR. Genomewide linkage scan for opioid dependence and related traits. Am J Hum Genet. 2006 May; 78(5):759-769. PMID: 16642432.
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    29. Quello SB, Brady KT, Sonne SC. Mood disorders and substance use disorder: a complex comorbidity. Sci Pract Perspect. 2005 Dec; 3(1):13-21. PMID: 18552741.
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    30. Back SE, Jackson JL, Sonne S, Brady KT. Alcohol dependence and posttraumatic stress disorder: differences in clinical presentation and response to cognitive-behavioral therapy by order of onset. J Subst Abuse Treat. 2005 Jul; 29(1):29-37. PMID: 15979529.
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    31. Carter RE, Sonne SC, Brady KT. Practical considerations for estimating clinical trial accrual periods: application to a multi-center effectiveness study. BMC Med Res Methodol. 2005 Mar 30; 5:11. PMID: 15796782.
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    32. Brady KT, Sonne S, Anton RF, Randall CL, Back SE, Simpson K. Sertraline in the treatment of co-occurring alcohol dependence and posttraumatic stress disorder. Alcohol Clin Exp Res. 2005 Mar; 29(3):395-401. PMID: 15770115.
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    33. Labbate LA, Sonne SC, Randal CL, Anton RF, Brady KT. Does comorbid anxiety or depression affect clinical outcomes in patients with post-traumatic stress disorder and alcohol use disorders? Compr Psychiatry. 2004 Jul-Aug; 45(4):304-10. PMID: 15224273.
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    34. McRae AL, Sonne SC, Brady KT, Durkalski V, Palesch Y. A randomized, placebo-controlled trial of buspirone for the treatment of anxiety in opioid-dependent individuals. Am J Addict. 2004 Jan-Feb; 13(1):53-63. PMID: 14766438.
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    35. McRae AL, Brady KT, Mellman TA, Sonne SC, Killeen TK, Timmerman MA, Bayles-Dazet W. Comparison of nefazodone and sertraline for the treatment of posttraumatic stress disorder. Depress Anxiety. 2004; 19(3):190-6. PMID: 15129422.
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    36. Sonne SC, Back SE, Diaz Zuniga C, Randall CL, Brady KT. Gender differences in individuals with comorbid alcohol dependence and post-traumatic stress disorder. Am J Addict. 2003 Oct-Dec; 12(5):412-23. PMID: 14660155.
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    37. Back SE, Sonne SC, Killeen T, Dansky BS, Brady KT. Comparative profiles of women with PTSD and comorbid cocaine or alcohol dependence. Am J Drug Alcohol Abuse. 2003; 29(1):169-89. PMID: 12731687.
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    38. Brady KT, Sonne SC, Malcolm RJ, Randall CL, Dansky BS, Simpson K, Roberts JS, Brondino M. Carbamazepine in the treatment of cocaine dependence: subtyping by affective disorder. Exp Clin Psychopharmacol. 2002 Aug; 10(3):276-85. PMID: 12233988.
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    39. McRae AL, Brady KT, Sonne SC. Alcohol and substance abuse. Med Clin North Am. 2001 May; 85(3):779-801. PMID: 11349484.
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    40. Upadhyaya HP, Brady KT, Sethuraman G, Sonne SC, Malcolm R. Venlafaxine treatment of patients with comorbid alcohol/cocaine abuse and attention-deficit/hyperactivity disorder: a pilot study. J Clin Psychopharmacol. 2001 Feb; 21(1):116-8. PMID: 11199938.
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    41. Randall CL, Johnson MR, Thevos AK, Sonne SC, Thomas SE, Willard SL, Brady KT, Davidson JR. Paroxetine for social anxiety and alcohol use in dual-diagnosed patients. Depress Anxiety. 2001; 14(4):255-62. PMID: 11754136.
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    42. Markowitz JS, McRae AL, Sonne SC. Oral nutritional supplementation for the alcoholic patient: a brief overview. Ann Clin Psychiatry. 2000 Sep; 12(3):153-8. PMID: 10984005.
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    43. Sonne SC, Brady KT. Naltrexone for individuals with comorbid bipolar disorder and alcohol dependence. J Clin Psychopharmacol. 2000 Feb; 20(1):114-5. PMID: 10653225.
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    44. Sonne SC, Brady KT. Substance abuse and bipolar comorbidity. Psychiatr Clin North Am. 1999 Sep; 22(3):609-27, ix. PMID: 10550858.
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    45. Sonne SC, Brady KT. Valproate for alcoholics with bipolar disorder. Am J Psychiatry. 1999 Jul; 156(7):1122. PMID: 10401478.
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    46. Brady KT, Sonne SC. The role of stress in alcohol use, alcoholism treatment, and relapse. Alcohol Res Health. 1999; 23(4):263-71. PMID: 10890823.
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    47. Brady KT, Dansky BS, Sonne SC, Saladin ME. Posttraumatic stress disorder and cocaine dependence. Order of onset. Am J Addict. 1998; 7(2):128-35. PMID: 9598216.
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    48. Sonne SC, Brady KT. Diagnosis of personality disorders in cocaine-dependent individuals. Am J Addict. 1998; 7(1):1-6. PMID: 9522001.
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    49. Brady KT, Sonne SC, Roberts JM. Sertraline treatment of comorbid posttraumatic stress disorder and alcohol dependence. J Clin Psychiatry. 1995 Nov; 56(11):502-5. PMID: 7592501.
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    50. Morton WA, Sonne SC, Verga MA. Venlafaxine: a structurally unique and novel antidepressant. Ann Pharmacother. 1995 Apr; 29(4):387-95. PMID: 7633018.
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    51. Brady KT, Sonne SC, Anton R, Ballenger JC. Valproate in the treatment of acute bipolar affective episodes complicated by substance abuse: a pilot study. J Clin Psychiatry. 1995 Mar; 56(3):118-21. PMID: 7883730.
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    52. Brady KT, Sonne SC. The relationship between substance abuse and bipolar disorder. J Clin Psychiatry. 1995; 56 Suppl 3:19-24. PMID: 7883738.
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    53. Sonne SC, Brady KT, Morton WA. Substance abuse and bipolar affective disorder. J Nerv Ment Dis. 1994 Jun; 182(6):349-52. PMID: 8201307.
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    54. Morton WA, Sonne SC, Lydiard RB. Fluoxetine-associated side effects and suicidality. J Clin Psychopharmacol. 1993 Aug; 13(4):292-5. PMID: 8166790.
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    55. Morton WA, Sonne SC, Lydiard RB. Lithium side effects in the medically ill. Int J Psychiatry Med. 1993; 23(4):357-82. PMID: 8175248.
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