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Christian Schwabe

Title
InstitutionMedical University of South Carolina
DepartmentBiochemistry and Molecular Biology
AddressP.O. Box MSC 509
535E
173 Ashley Ave.
Phone843-792-9929
Fax843-792-1627
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Büllesbach EE, Schwabe C. Replacement of disulfides by amide bonds in the relaxin-like factor (RLF/INSL3) reveals a role for the A11-B10 link in transmembrane signaling. Biochemistry. 2012 May 22; 51(20):4198-205. PMID: 22574850.
      View in: PubMed
    2. Schwabe C, Büllesbach EE. The "hot wires" of the relaxin-like factor (Insl3). Ann N Y Acad Sci. 2009 Apr; 1160:93-8. PMID: 19416166.
      View in: PubMed
    3. Büllesbach EE, Hass MA, Jensen MR, Hansen DF, Kristensen SM, Schwabe C, Led JJ. Solution structure of a conformationally restricted fully active derivative of the human relaxin-like factor. Biochemistry. 2008 Dec 16; 47(50):13308-17. PMID: 19086273.
      View in: PubMed
    4. Schwabe C. Embryotic evolution: an ancient question, a new answer. Cell Cycle. 2008 Jun 01; 7(11):1503-6. PMID: 18550919.
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    5. Büllesbach EE, Boockfor FR, Fullbright G, Schwabe C. Cryptorchidism induced in normal rats by the relaxin-like factor inhibitor. Reproduction. 2008 Mar; 135(3):351-5. PMID: 18299428.
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    6. Steinetz BG, Williams AJ, Lust G, Schwabe C, Büllesbach EE, Goldsmith LT. Transmission of relaxin and estrogens to suckling canine pups via milk and possible association with hip joint laxity. Am J Vet Res. 2008 Jan; 69(1):59-67. PMID: 18167088.
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    7. Büllesbach EE, Schwabe C. Structure of the transmembrane signal initiation site of the relaxin-like factor (RLF/INSL3). Biochemistry. 2007 Aug 28; 46(34):9722-7. PMID: 17676766.
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    8. Schwabe C, Büllesbach EE. Relaxin, the relaxin-like factor and their receptors. Adv Exp Med Biol. 2007; 612:14-25. PMID: 18161478.
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    9. Büllesbach EE, Schwabe C. The mode of interaction of the relaxin-like factor (RLF) with the leucine-rich repeat G protein-activated receptor 8. J Biol Chem. 2006 Sep 08; 281(36):26136-43. PMID: 16844694.
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    10. Millar L, Streiner N, Webster L, Yamamoto S, Okabe R, Kawamata T, Shimoda J, Büllesbach E, Schwabe C, Bryant-Greenwood G. Early placental insulin-like protein (INSL4 or EPIL) in placental and fetal membrane growth. Biol Reprod. 2005 Oct; 73(4):695-702. PMID: 15958731.
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    11. Bryant-Greenwood GD, Yamamoto SY, Lowndes KM, Webster LE, Parg SS, Amano A, Bullesbach EE, Schwabe C, Millar LK. Human decidual relaxin and preterm birth. Ann N Y Acad Sci. 2005 May; 1041:338-44. PMID: 15956731.
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    12. Büllesbach EE, Schwabe C. LGR8 signal activation by the relaxin-like factor. J Biol Chem. 2005 Apr 15; 280(15):14586-90. PMID: 15708846.
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    13. Büllesbach EE, Schwabe C. The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7. J Biol Chem. 2005 Apr 08; 280(14):14051-6. PMID: 15695505.
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    14. Schwabe C. Chemistry and biodiversity. Chem Biodivers. 2004 Oct; 1(10):1584-8. PMID: 17191802.
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    15. Büllesbach EE, Schwabe C. Synthetic cross-links arrest the C-terminal region of the relaxin-like factor in an active conformation. Biochemistry. 2004 Jun 29; 43(25):8021-8. PMID: 15209497.
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    16. Whittaker PG, Edwards JR, Randolph C, Büllesbach EE, Schwabe C, Steinetz BG. Abnormal relaxin secretion during pregnancy in women with type 1 diabetes. Exp Biol Med (Maywood). 2003 Jan; 228(1):33-40. PMID: 12524470.
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    17. Schwabe C. Genomic potential hypothesis of evolution: a concept of biogenesis in habitable spaces of the universe. Anat Rec. 2002 Nov 01; 268(3):171-9. PMID: 12382315.
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    18. Adham IM, Steding G, Thamm T, Büllesbach EE, Schwabe C, Paprotta I, Engel W. The overexpression of the insl3 in female mice causes descent of the ovaries. Mol Endocrinol. 2002 Feb; 16(2):244-52. PMID: 11818498.
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    19. Büllesbach EE, Schwabe C. The primary structure and the disulfide links of the bovine relaxin-like factor (RLF). Biochemistry. 2002 Jan 08; 41(1):274-81. PMID: 11772026.
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    20. Boockfor FR, Fullbright G, Büllesbach EE, Schwabe C. Relaxin-like factor (RLF) serum concentrations and gubernaculum RLF receptor display in relation to pre- and neonatal development of rats. Reproduction. 2001 Dec; 122(6):899-906. PMID: 11732985.
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    21. Büllesbach EE, Schwabe C. Synthesis and conformational analysis of the insulin-like 4 gene product. J Pept Res. 2001 Jan; 57(1):77-83. PMID: 11168891.
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    22. Büllesbach EE, Schwabe C. The relaxin receptor-binding site geometry suggests a novel gripping mode of interaction. J Biol Chem. 2000 Nov 10; 275(45):35276-80. PMID: 10956652.
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    23. Büllesbach EE, Schwabe C. Specific, high affinity relaxin-like factor receptors. J Biol Chem. 1999 Aug 06; 274(32):22354-8. PMID: 10428805.
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    24. Büllesbach EE, Rhodes R, Rembiesa B, Schwabe C. The relaxin-like factor is a hormone. Endocrine. 1999 Apr; 10(2):167-9. PMID: 10451226.
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    25. Büllesbach EE, Schwabe C. Tryptophan B27 in the relaxin-like factor (RLF) is crucial for RLF receptor-binding. Biochemistry. 1999 Mar 09; 38(10):3073-8. PMID: 10074360.
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    26. Büllesbach EE, Schwabe C, Lacy ER. Identification of a glycosylated relaxin-like molecule from the male Atlantic stingray, Dasyatis sabina. Biochemistry. 1997 Sep 02; 36(35):10735-41. PMID: 9271504.
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    27. Büllesbach EE, Schwabe C. The chemical synthesis of rat relaxin and the unexpectedly high potency of the synthetic hormone in the mouse. Eur J Biochem. 1996 Oct 15; 241(2):533-7. PMID: 8917452.
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    28. Nusser KD, Schwabe C, Stephen Frawley L. A milk-borne factor inhibits mammotrope differentiation in the neonatal rat. Endocrine. 1996 Oct; 5(2):141-5. PMID: 21153104.
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    29. Büllesbach EE, Steinetz BG, Schwabe C. Chemical synthesis of a Zwitterhormon, insulaxin, and of a relaxin-like bombyxin derivative. Biochemistry. 1996 Jul 30; 35(30):9754-60. PMID: 8703947.
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    30. Büllesbach EE, Schwabe C. Introduction of relaxin properties into other hormones of insulin-like structure. SAAS Bull Biochem Biotechnol. 1996; 9:63-8. PMID: 8652134.
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    31. Büllesbach EE, Schwabe C. Structural contribution of the A-chain loop in relaxin. Int J Pept Protein Res. 1995 Sep-Oct; 46(3-4):238-43. PMID: 8537177.
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    32. Büllesbach EE, Schwabe C. A novel Leydig cell cDNA-derived protein is a relaxin-like factor. J Biol Chem. 1995 Jul 07; 270(27):16011-5. PMID: 7608161.
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    33. Schwabe C, Büllesbach EE. Relaxin: structures, functions, promises, and nonevolution. FASEB J. 1994 Nov; 8(14):1152-60. PMID: 7958621.
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    34. Büllesbach EE, Schwabe C. Functional importance of the A chain loop in relaxin and insulin. J Biol Chem. 1994 May 06; 269(18):13124-8. PMID: 8175738.
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    35. Büllesbach EE, Schwabe C. Mouse relaxin: synthesis and biological activity of the first relaxin with an unusual crosslinking pattern. Biochem Biophys Res Commun. 1993 Oct 15; 196(1):311-9. PMID: 8216305.
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    36. Yang S, Heyn H, Zhang YZ, Büllesbach EE, Schwabe C. The expression of human relaxin in yeast. Arch Biochem Biophys. 1993 Feb 01; 300(2):734-7. PMID: 8382033.
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    37. Büllesbach EE, Yang S, Schwabe C. The receptor-binding site of human relaxin II. A dual prong-binding mechanism. J Biol Chem. 1992 Nov 15; 267(32):22957-60. PMID: 1331071.
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    38. Yang S, Rembiesa B, Büllesbach EE, Schwabe C. Relaxin receptors in mice: demonstration of ligand binding in symphyseal tissues and uterine membrane fragments. Endocrinology. 1992 Jan; 130(1):179-85. PMID: 1309327.
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    39. Kineman RD, Büllesbach EE, Schwabe C, Boggs KP, Frawley LS. Purification from human pregnancy serum of a low molecular weight mitogen similar to placental lactogen and growth hormone. Proc Soc Exp Biol Med. 1991 Sep; 197(4):441-9. PMID: 1871155.
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    40. Büllesbach EE, Schwabe C. Total synthesis of human relaxin and human relaxin derivatives by solid-phase peptide synthesis and site-directed chain combination. J Biol Chem. 1991 Jun 15; 266(17):10754-61. PMID: 2040595.
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    41. Büllesbach EE, Schwabe C. Monobiotinylated relaxins. Preparation and chemical properties of the mono(biotinyl-epsilon-aminohexanoyl) porcine relaxin. Int J Pept Protein Res. 1990 May; 35(5):416-23. PMID: 2376467.
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    42. Schwabe C. New thoughts on the evolution of hormone-receptor systems. Comp Biochem Physiol A Comp Physiol. 1990; 97(2):101-6. PMID: 1982931.
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    43. Schwabe C, Büllesbach EE. Relaxin. Comp Biochem Physiol B. 1990; 96(1):15-21. PMID: 2194740.
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    44. Schwabe C, Büllesbach EE, Heyn H, Yoshioka M. Cetacean relaxin. Isolation and sequence of relaxins from Balaenoptera acutorostrata and Balaenoptera edeni. J Biol Chem. 1989 Jan 15; 264(2):940-3. PMID: 2910872.
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    45. Büllesbach EE, Schwabe C. On the receptor binding site of relaxins. Int J Pept Protein Res. 1988 Nov; 32(5):361-7. PMID: 2850280.
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    46. Collawn JF, Gowan LK, Crow H, Schwabe C, Fish WW. Isolation and partial amino acid sequence of three subunit species of porcine spleen ferritin: evidence of multiple H subunits. Arch Biochem Biophys. 1987 Nov 15; 259(1):105-13. PMID: 3688879.
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    47. Pappaioanou M, Schwabe CW, Sard DM. An evolving pattern of human hydatid disease transmission in the United States. Am J Trop Med Hyg. 1977 Jul; 26(4):732-42. PMID: 329700.
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    48. Kilejian A, Schwabe CW. Studies on the polysaccharides of the Echinococcus granulosus cyst, with observations on a possible mechanism for laminated membrane formation. Comp Biochem Physiol B. 1971 Sep 15; 40(1):25-36. PMID: 5141400.
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