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John K. Orak

Title
InstitutionMedical University of South Carolina
DepartmentPediatric Nephrology
AddressP.O. Box MSC 608
HE 316I
96 Jonathan Lucas St.
Phone843-792-8904
Fax843-792-2033
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Shatat IF, Jakson SM, Blue AE, Johnson MA, Orak JK, Kalpatthi R. Masked hypertension is prevalent in children with sickle cell disease: a Midwest Pediatric Nephrology Consortium study. Pediatr Nephrol. 2013 Jan; 28(1):115-20. PMID: 22886281.
      View in: PubMed
    2. Shatat IF, Taber DJ, Shrivastava S, Weimert NA, Sas DJ, Chavin KD, Orak JK, Baliga PK. Graft outcomes in pediatric kidney transplantation: focus on the role of race. Saudi J Kidney Dis Transpl. 2012 Jul; 23(4):684-92. PMID: 22805378.
      View in: PubMed
    3. Paintlia AS, Paintlia MK, Singh AK, Orak JK, Singh I. Activation of PPAR-? and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells. Glia. 2010 Nov 01; 58(14):1669-85. PMID: 20578043.
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    4. Jensen CJ, Shrivastava S, Taber DJ, Weimert NA, Shatat IF, Orak J, Chavin KD, Baliga PK. A critical analysis of racial difference with mycophenolate mofetil (MMF) dosing, clinical outcomes and adverse effects in pediatric kidney transplant patients. Clin Transplant. 2011 Jul-Aug; 25(4):534-40. PMID: 20636410.
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    5. Becton LJ, Kalpatthi RV, Rackoff E, Disco D, Orak JK, Jackson SM, Shatat IF. Prevalence and clinical correlates of microalbuminuria in children with sickle cell disease. Pediatr Nephrol. 2010 Aug; 25(8):1505-11. PMID: 20505954.
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    6. Shunmugavel A, Khan M, Te Chou PC, Dhindsa RK, Martin MM, Copay AG, Subach BR, Schuler TC, Bilgen M, Orak JK, Singh I. Simvastatin protects bladder and renal functions following spinal cord injury in rats. J Inflamm (Lond). 2010 Apr 19; 7:17. PMID: 20403180.
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    7. Sas DJ, Hulsey TC, Shatat IF, Orak JK. Increasing incidence of kidney stones in children evaluated in the emergency department. J Pediatr. 2010 Jul; 157(1):132-7. PMID: 20362300.
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    8. Lin A, Sekhon C, Sekhon B, Smith A, Chavin K, Orak J, Singh I, Singh A. Attenuation of ischemia-reperfusion injury in a canine model of autologous renal transplantation. Transplantation. 2004 Sep 15; 78(5):654-9. PMID: 15371664.
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    9. Sekhon CS, Sekhon BK, Singh I, Orak JK, Singh AK. Attenuation of renal ischemia/reperfusion injury by a triple drug combination therapy. J Nephrol. 2003 Jan-Feb; 16(1):63-74. PMID: 12649537.
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    10. Mehta A, Sekhon CP, Giri S, Orak JK, Singh AK. Attenuation of ischemia/reperfusion induced MAP kinases by N-acetyl cysteine, sodium nitroprusside and phosphoramidon. Mol Cell Biochem. 2002 Nov; 240(1-2):19-29. PMID: 12487368.
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    11. Dobashi K, Singh I, Orak JK, Asayama K, Singh AK. Combination therapy of N-acetylcysteine, sodium nitroprusside and phosphoramidon attenuates ischemia-reperfusion injury in rat kidney. Mol Cell Biochem. 2002 Nov; 240(1-2):9-17. PMID: 12487367.
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    12. Contreras MA, Khan M, Smith BT, Cimini AM, Gilg AG, Orak J, Singh I, Singh AK. Endotoxin induces structure-function alterations of rat liver peroxisomes: Kupffer cells released factors as possible modulators. Hepatology. 2000 Feb; 31(2):446-55. PMID: 10655269.
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    13. Dobashi K, Ghosh B, Orak JK, Singh I, Singh AK. Kidney ischemia-reperfusion: modulation of antioxidant defenses. Mol Cell Biochem. 2000 Feb; 205(1-2):1-11. PMID: 10821417.
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    14. Singh AK, Dobashi K, Gupta MP, Asayama K, Singh I, Orak JK. Manganese superoxide dismutase in rat liver peroxisomes: biochemical and immunochemical evidence. Mol Cell Biochem. 1999 Jul; 197(1-2):7-12. PMID: 10485318.
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    15. Gupta M, Dobashi K, Greene EL, Orak JK, Singh I. Studies on hepatic injury and antioxidant enzyme activities in rat subcellular organelles following in vivo ischemia and reperfusion. Mol Cell Biochem. 1997 Nov; 176(1-2):337-47. PMID: 9406179.
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    16. Singh AK, Gupta MK, Orak JK. Antioxidant enzymes in peroxisomes: effect of ischemia. Ann N Y Acad Sci. 1996 Dec 27; 804:696-7. PMID: 9019999.
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    17. Hanevold CD, Lazarchick J, Constantin MA, Hiott KL, Orak JK. Acquired free protein S deficiency in children with steroid resistant nephrosis. Ann Clin Lab Sci. 1996 May-Jun; 26(3):279-82. PMID: 8726222.
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    18. Ghosh B, Hanevold CD, Dobashi K, Orak JK, Singh I. Tissue differences in antioxidant enzyme gene expression in response to endotoxin. Free Radic Biol Med. 1996; 21(4):533-40. PMID: 8886805.
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    19. Singh AK, Dhaunsi GS, Gupta MP, Orak JK, Asayama K, Singh I. Demonstration of glutathione peroxidase in rat liver peroxisomes and its intraorganellar distribution. Arch Biochem Biophys. 1994 Dec; 315(2):331-8. PMID: 7986075.
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    20. Dhaunsi GS, Singh I, Orak JK, Singh AK. Antioxidant enzymes in ciprofibrate-induced oxidative stress. Carcinogenesis. 1994 Sep; 15(9):1923-30. PMID: 7923586.
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    21. Singh I, Dhaunsi GS, Orak JK, Rajagopalan PR, Singh AK. CuZn superoxide dismutase: intraorganellar distribution in peroxisomes. Ann N Y Acad Sci. 1994 Jun 17; 723:406-8. PMID: 8030898.
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    22. Orak JK, Singh AK, Rajagopalan PR, Singh I. Morphological analysis of mitochondrial integrity in prolonged cold renal ischemia utilizing Euro-Collins versus University of Wisconsin preservation solution in a whole organ model. Transplant Proc. 1994 Feb; 26(1):122-5. PMID: 8108903.
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    23. Borowicz MR, Hanevold CD, Cofer JB, Bromberg JS, Orak JK, Rajagopalan PR. Extrinsic compression in the iliac fossa can cause renal vein occlusion in pediatric kidney recipients but graft loss can be prevented. Transplant Proc. 1994 Feb; 26(1):119-20. PMID: 8108901.
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    24. Gulati S, Ainol L, Orak J, Singh AK, Singh I. Alterations of peroxisomal function in ischemia-reperfusion injury of rat kidney. Biochim Biophys Acta. 1993 Oct 20; 1182(3):291-8. PMID: 8399363.
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    25. Singh I, Gulati S, Orak JK, Singh AK. Expression of antioxidant enzymes in rat kidney during ischemia-reperfusion injury. Mol Cell Biochem. 1993 Aug 25; 125(2):97-104. PMID: 8283974.
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    26. Gulati S, Singh AK, Irazu C, Orak J, Rajagopalan PR, Fitts CT, Singh I. Ischemia-reperfusion injury: biochemical alterations in peroxisomes of rat kidney. Arch Biochem Biophys. 1992 May 15; 295(1):90-100. PMID: 1575521.
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    27. Dhaunsi GS, Gulati S, Singh AK, Orak JK, Asayama K, Singh I. Demonstration of Cu-Zn superoxide dismutase in rat liver peroxisomes. Biochemical and immunochemical evidence. J Biol Chem. 1992 Apr 05; 267(10):6870-3. PMID: 1551895.
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    28. Orak JK, Rajagopalan PR, Hanevold CD, Hiott KL. Acute peritoneal dialysis utilizing a non-luminal channeled catheter in infants. Adv Perit Dial. 1992; 8:429-32. PMID: 1361841.
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    29. Irazu CE, Rajagopalan PR, Orak JK, Fitts CT, Singh I. Mitochondrial membrane fluidity changes in renal ischemia. J Exp Pathol. 1990; 5(1):1-6. PMID: 2398421.
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    30. Dhaunsi GS, Singh AK, Orak J, Singh I. Lipid peroxidation and oxidation of lignoceric acid in kidneys from thioridazine treated rats. J Exp Pathol. 1990; 5(4):177-86. PMID: 2101135.
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    31. Irazu CE, Ruidera E, Singh I, Orak JK, Fitts CT, Rajagopalan PR. Effect of ischemia and 24 hour reperfusion on ATP synthesis in the rat kidney. J Exp Pathol. 1989; 4(1):29-36. PMID: 2778550.
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    32. Ruidera E, Irazu CE, Rajagopalan PR, Orak JK, Fitts CT, Singh I. Fatty acid metabolism in renal ischemia. Lipids. 1988 Sep; 23(9):882-4. PMID: 3185124.
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    33. Garin EH, Orak JK, Hiott KL, Sutherland SE. Cyclosporine therapy for steroid-resistant nephrotic syndrome. A controlled study. Am J Dis Child. 1988 Sep; 142(9):985-8. PMID: 3046332.
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    34. Benton O, Lazarchick J, Orak JK, Turner WR. Use of a bleeding time determination in the evaluation of unexplained hematuria. J Urol. 1987 Mar; 137(3):527-8. PMID: 3493354.
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    35. Orak JK, Garin EH. Medical sequelae of reflux nephropathy. Semin Urol. 1986 May; 4(2):131-4. PMID: 3715263.
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    36. Fennell RS, Orak JK, Hudson T, Garin EH, Iravani A, Richard GA, Hislop SL, Knight MI. Continuous ambulatory peritoneal dialysis in a program for children with end stage renal disease. Eur J Pediatr. 1984 Aug; 142(3):174-8. PMID: 6468441.
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    37. Moazam F, Orak JK, Fennell RS, Richard GA, Talbert JL. Total parathyroidectomy and autotransplantation for tertiary hyperparathyroidism in children with chronic renal failure. J Pediatr Surg. 1984 Aug; 19(4):389-93. PMID: 6481583.
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    38. Fennell RS, Orak JK, Hudson T, Garin EH, Iravani A, Van Deusen WJ, Howard R, Pfaff WW, Walker RD, Richard GA. Growth in children with various therapies for end-stage renal disease. Am J Dis Child. 1984 Jan; 138(1):28-31. PMID: 6419583.
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    39. Nanni GS, Hawkins IF, Orak JK. Control of hypertension by ethanol renal ablation. Radiology. 1983 Jul; 148(1):51-4. PMID: 6856864.
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    40. Fennell RS, Orak JK, Garin EH, Iravani A, Richard G, St John M. Continuous ambulatory peritoneal dialysis in a pediatric population. Am J Dis Child. 1983 Apr; 137(4):388-92. PMID: 6829519.
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