Jonathan J. Halford

Title
InstitutionMedical University of South Carolina
DepartmentNeurology
AddressP.O. Box MSC 606
325
96 Jonathan Lucas St.
Phone843-792-3221
Fax843-792-0029
vCardDownload vCard

    Collapse Overview 
    Collapse keywords
    Central Nervous System, Epilepsy

    Collapse ORNG Applications 
    Collapse studies/trials

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Halford JJ, Sperling MR, Arkilo D, Asgharnejad M, Zinger C, Xu R, During M, French JA. A phase 1b/2a study of soticlestat as adjunctive therapy in participants with developmental and/or epileptic encephalopathies. Epilepsy Res. 2021 Apr 22; 174:106646. PMID: 33940389.
      Citations:    
    2. Halford JJ, Clunie DA, Brinkmann BH, Krefting D, Rémi J, Rosenow F, Husain A, Fürbass F, Andrew Ehrenberg J, Winkler S. Standardization of neurophysiology signal data into the DICOM® standard. Clin Neurophysiol. 2021 Apr; 132(4):993-997. PMID: 33662849.
      Citations:    
    3. Ge W, Jing J, An S, Herlopian A, Ng M, Struck AF, Appavu B, Johnson EL, Osman G, Haider HA, Karakis I, Kim JA, Halford JJ, Dhakar MB, Sarkis RA, Swisher CB, Schmitt S, Lee JW, Tabaeizadeh M, Rodriguez A, Gaspard N, Gilmore E, Herman ST, Kaplan PW, Pathmanathan J, Hong S, Rosenthal ES, Zafar S, Sun J, Brandon Westover M. Deep active learning for Interictal Ictal Injury Continuum EEG patterns. J Neurosci Methods. 2021 Mar 01; 351:108966. PMID: 33131680.
      Citations:    
    4. Thomas J, Jin J, Thangavel P, Bagheri E, Yuvaraj R, Dauwels J, Rathakrishnan R, Halford JJ, Cash SS, Westover B. Automated Detection of Interictal Epileptiform Discharges from Scalp Electroencephalograms by Convolutional Neural Networks. Int J Neural Syst. 2020 Nov; 30(11):2050030. PMID: 32812468.
      Citations:    
    5. Nair DR, Laxer KD, Weber PB, Murro AM, Park YD, Barkley GL, Smith BJ, Gwinn RP, Doherty MJ, Noe KH, Zimmerman RS, Bergey GK, Anderson WS, Heck C, Liu CY, Lee RW, Sadler T, Duckrow RB, Hirsch LJ, Wharen RE, Tatum W, Srinivasan S, McKhann GM, Agostini MA, Alexopoulos AV, Jobst BC, Roberts DW, Salanova V, Witt TC, Cash SS, Cole AJ, Worrell GA, Lundstrom BN, Edwards JC, Halford JJ, Spencer DC, Ernst L, Skidmore CT, Sperling MR, Miller I, Geller EB, Berg MJ, Fessler AJ, Rutecki P, Goldman AM, Mizrahi EM, Gross RE, Shields DC, Schwartz TH, Labar DR, Fountain NB, Elias WJ, Olejniczak PW, Villemarette-Pittman NR, Eisenschenk S, Roper SN, Boggs JG, Courtney TA, Sun FT, Seale CG, Miller KL, Skarpaas TL, Morrell MJ. Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy. Neurology. 2020 09 01; 95(9):e1244-e1256. PMID: 32690786.
      Citations:    
    6. Halford JJ, Edwards JC. Seizure freedom as an outcome in epilepsy treatment clinical trials. Acta Neurol Scand. 2020 Aug; 142(2):91-107. PMID: 32353166.
      Citations:    
    7. Sperling MR, Klein P, Aboumatar S, Gelfand M, Halford JJ, Krauss GL, Rosenfeld WE, Vossler DG, Wechsler R, Borchert L, Kamin M. Cenobamate (YKP3089) as adjunctive treatment for uncontrolled focal seizures in a large, phase 3, multicenter, open-label safety study. Epilepsia. 2020 06; 61(6):1099-1108. PMID: 32396252.
      Citations:    
    8. Jing J, Sun H, Kim JA, Herlopian A, Karakis I, Ng M, Halford JJ, Maus D, Chan F, Dolatshahi M, Muniz C, Chu C, Sacca V, Pathmanathan J, Ge W, Dauwels J, Lam A, Cole AJ, Cash SS, Westover MB. Development of Expert-Level Automated Detection of Epileptiform Discharges During Electroencephalogram Interpretation. JAMA Neurol. 2020 01 01; 77(1):103-108. PMID: 31633740.
      Citations:    
    9. Cardenas DP, Halford JJ, Whitmire LE, Morgan LC, Lie OV, Jetter GM, Cavazos JE. Automated Processing of Single-Channel Surface Electromyography From Generalized Tonic-Clonic Seizures to Inform Semiology. J Clin Neurophysiol. 2020 Jan; 37(1):56-61. PMID: 31335562.
      Citations:    
    10. Jing J, Herlopian A, Karakis I, Ng M, Halford JJ, Lam A, Maus D, Chan F, Dolatshahi M, Muniz CF, Chu C, Sacca V, Pathmanathan J, Ge W, Sun H, Dauwels J, Cole AJ, Hoch DB, Cash SS, Westover MB. Interrater Reliability of Experts in Identifying Interictal Epileptiform Discharges in Electroencephalograms. JAMA Neurol. 2020 01 01; 77(1):49-57. PMID: 31633742.
      Citations:    
    11. Thiele E, Marsh E, Mazurkiewicz-Beldzinska M, Halford JJ, Gunning B, Devinsky O, Checketts D, Roberts C. Cannabidiol in patients with Lennox-Gastaut syndrome: Interim analysis of an open-label extension study. Epilepsia. 2019 03; 60(3):419-428. PMID: 30740695.
      Citations:    
    12. Stamoulis C, Connolly J, Axeen E, Kaulas H, Bolton J, Dorfman K, Halford JJ, Duffy FH, Treves ST, Pearl PL. Non-invasive Seizure Localization with Ictal Single-Photon Emission Computed Tomography is Impacted by Preictal/Early Ictal Network Dynamics. IEEE Trans Biomed Eng. 2018 Nov 09. PMID: 30418877.
      Citations:    
    13. Halford JJ, Westover MB, LaRoche SM, Macken MP, Kutluay E, Edwards JC, Bonilha L, Kalamangalam GP, Ding K, Hopp JL, Arain A, Dawson RA, Martz GU, Wolf BJ, Waters CG, Dean BC. Interictal Epileptiform Discharge Detection in EEG in Different Practice Settings. J Clin Neurophysiol. 2018 Sep; 35(5):375-380. PMID: 30028830.
      Citations:    
    14. Husain AM, Lee JW, Kolls BJ, Hirsch LJ, Halford JJ, Gupta PK, Minazad Y, Jones JM, LaRoche SM, Herman ST, Swisher CB, Sinha SR, Palade A, Dombrowski KE, Gallentine WB, Hahn CD, Gerard EE, Bhapkar M, Lokhnygina Y, Westover MB. Randomized trial of lacosamide versus fosphenytoin for nonconvulsive seizures. Ann Neurol. 2018 06; 83(6):1174-1185. PMID: 29733464.
      Citations:    
    15. Halford JJ, Sperling MR, Nair DR, Dlugos DJ, Tatum WO, Harvey J, French JA, Pollard JR, Faught E, Noe KH, Henry TR, Jetter GM, Lie OV, Morgan LC, Girouard MR, Cardenas DP, Whitmire LE, Cavazos JE. Detection of generalized tonic-clonic seizures using surface electromyographic monitoring. Epilepsia. 2017 11; 58(11):1861-1869. PMID: 28980702.
      Citations:    
    16. Bolen RD, Edwards JC, Halford JJ. Aliasing of 60-Hz Artifact as a Result of Compressed Time Base. J Clin Neurophysiol. 2017 Sep; 34(5):e19-e22. PMID: 27749503.
      Citations:    
    17. Bagheri E, Dauwels J, Dean BC, Waters CG, Westover MB, Halford JJ. Interictal epileptiform discharge characteristics underlying expert interrater agreement. Clin Neurophysiol. 2017 10; 128(10):1994-2005. PMID: 28837905.
      Citations:    
    18. Westover MB, Halford JJ, Bianchi MT. What it should mean for an algorithm to pass a statistical Turing test for detection of epileptiform discharges. Clin Neurophysiol. 2017 07; 128(7):1406-1407. PMID: 28495216.
      Citations:    
    19. Halford JJ, Arain A, Kalamangalam GP, LaRoche SM, Leonardo B, Basha M, Azar NJ, Kutluay E, Martz GU, Bethany WJ, Waters CG, Dean BC. Characteristics of EEG Interpreters Associated With Higher Interrater Agreement. J Clin Neurophysiol. 2017 Mar; 34(2):168-173. PMID: 27662336.
      Citations:    
    20. Halford JJ, Schalkoff RJ, Satterfield KE, Martz GU, Kutluay E, Waters CG, Dean BC. Comparison of a Novel Dry Electrode Headset to Standard Routine EEG in Veterans. J Clin Neurophysiol. 2016 Dec; 33(6):530-537. PMID: 27300074.
      Citations:    
    21. Stamoulis C, Verma N, Kaulas H, Halford JJ, Duffy FH, Pearl PL, Treves ST. The promise of subtraction ictal SPECT co-registered to MRI for improved seizure localization in pediatric epilepsies: Affecting factors and relationship to the surgical outcome. Epilepsy Res. 2017 01; 129:59-66. PMID: 27918961.
      Citations:    
    22. Al Kasab S, Dawson RA, Jaramillo JL, Halford JJ. Correlation of seizure frequency and medication down-titration rate during video-EEG monitoring. Epilepsy Behav. 2016 11; 64(Pt A):51-56. PMID: 27732916.
      Citations:    
    23. Stead M, Halford JJ. Proposal for a Standard Format for Neurophysiology Data Recording and Exchange. J Clin Neurophysiol. 2016 Oct; 33(5):403-413. PMID: 26808620.
      Citations:    
    24. Halford JJ, Sabau D, Drislane FW, Tsuchida TN, Sinha SR. American Clinical Neurophysiology Society Guideline 4: Recording Clinical EEG on Digital Media. J Clin Neurophysiol. 2016 Aug; 33(4):317-9. PMID: 27482787.
      Citations:    
    25. Sinha SR, Sullivan L, Sabau D, San-Juan D, Dombrowski KE, Halford JJ, Hani AJ, Drislane FW, Stecker MM. American Clinical Neurophysiology Society Guideline 1: Minimum Technical Requirements for Performing Clinical Electroencephalography. J Clin Neurophysiol. 2016 Aug; 33(4):303-7. PMID: 27482788.
      Citations:    
    26. Tsuchida TN, Acharya JN, Halford JJ, Kuratani JD, Sinha SR, Stecker MM, Tatum WO, Drislane FW. American Clinical Neurophysiology Society: EEG Guidelines Introduction. J Clin Neurophysiol. 2016 Aug; 33(4):301-2. PMID: 27482792.
      Citations:    
    27. Haider HA, Esteller R, Hahn CD, Westover MB, Halford JJ, Lee JW, Shafi MM, Gaspard N, Herman ST, Gerard EE, Hirsch LJ, Ehrenberg JA, LaRoche SM. Sensitivity of quantitative EEG for seizure identification in the intensive care unit. Neurology. 2016 Aug 30; 87(9):935-44. PMID: 27466474.
      Citations:    
    28. Sinha SR, Sullivan LR, Sabau D, Orta DSJ, Dombrowski KE, Halford JJ, Hani AJ, Drislane FW, Stecker MM. American Clinical Neurophysiology Society Guideline 1: Minimum Technical Requirements for Performing Clinical Electroencephalography. Neurodiagn J. 2016; 56(4):235-244. PMID: 28436800.
      Citations:    
    29. Halford JJ, Sabau D, Drislane FW, Tsuchida TN, Sinha SR. American Clinical Neurophysiology Society Guideline 4: Recording Clinical EEG on Digital Media. Neurodiagn J. 2016; 56(4):261-265. PMID: 28436799.
      Citations:    
    30. Tsuchida TN, Acharya JN, Halford JJ, Kuratani JD, Sinha SR, Stecker MM, Tatum WO, Drislane FW. American Clinical Neurophysiology Society: EEG Guidelines Introduction. Neurodiagn J. 2016; 56(4):231-234. PMID: 28436786.
      Citations:    
    31. Fürbass F, Hartmann MM, Halford JJ, Koren J, Herta J, Gruber A, Baumgartner C, Kluge T. Automatic detection of rhythmic and periodic patterns in critical care EEG based on American Clinical Neurophysiology Society (ACNS) standardized terminology. Neurophysiol Clin. 2015 Sep; 45(3):203-13. PMID: 26363685.
      Citations:    
    32. Foreman B, Mahulikar A, Tadi P, Claassen J, Szaflarski J, Halford JJ, Dean BC, Kaplan PW, Hirsch LJ, LaRoche S. Generalized periodic discharges and 'triphasic waves': A blinded evaluation of inter-rater agreement and clinical significance. Clin Neurophysiol. 2016 Feb; 127(2):1073-1080. PMID: 26294138.
      Citations:    
    33. Lee D, Kalu U, Halford JJ, Biton V, Cloyd J, Klein P, Bekersky I, Peng G, Dheerendra S, Tolbert D. Intravenous carbamazepine as short-term replacement therapy for oral carbamazepine in adults with epilepsy: Pooled tolerability results from two open-label trials. Epilepsia. 2015 Jun; 56(6):906-14. PMID: 25912051.
      Citations:    
    34. Sahlem GL, Badran BW, Halford JJ, Williams NR, Korte JE, Leslie K, Strachan M, Breedlove JL, Runion J, Bachman DL, Uhde TW, Borckardt JJ, George MS. Oscillating Square Wave Transcranial Direct Current Stimulation (tDCS) Delivered During Slow Wave Sleep Does Not Improve Declarative Memory More Than Sham: A Randomized Sham Controlled Crossover Study. Brain Stimul. 2015 May-Jun; 8(3):528-34. PMID: 25795621.
      Citations:    
    35. Halford JJ. One ring to dissolve them all. Epilepsy Curr. 2015 Jan-Feb; 15(1):52-3. PMID: 25678894.
      Citations:    
    36. Halford JJ, Shiau D, Desrochers JA, Kolls BJ, Dean BC, Waters CG, Azar NJ, Haas KF, Kutluay E, Martz GU, Sinha SR, Kern RT, Kelly KM, Sackellares JC, LaRoche SM. Inter-rater agreement on identification of electrographic seizures and periodic discharges in ICU EEG recordings. Clin Neurophysiol. 2015 Sep; 126(9):1661-9. PMID: 25481336.
      Citations:    
    37. Zhou J, Schalkoff RJ, Dean BC, Halford JJ. A study of morphology-based wavelet features and multiple-wavelet strategy for EEG signal classification: results and selected statistical analysis. Annu Int Conf IEEE Eng Med Biol Soc. 2013; 2013:5998-6002. PMID: 24111106.
      Citations:    
    38. Halford JJ, Schalkoff RJ, Zhou J, Benbadis SR, Tatum WO, Turner RP, Sinha SR, Fountain NB, Arain A, Pritchard PB, Kutluay E, Martz G, Edwards JC, Waters C, Dean BC. Standardized database development for EEG epileptiform transient detection: EEGnet scoring system and machine learning analysis. J Neurosci Methods. 2013 Jan 30; 212(2):308-16. PMID: 23174094.
      Citations:    
    39. Zhou J, Schalkoff RJ, Dean BC, Halford JJ. Morphology-based wavelet features and multiple mother wavelet strategy for spike classification in EEG signals. Annu Int Conf IEEE Eng Med Biol Soc. 2012; 2012:3959-62. PMID: 23366794.
      Citations:    
    40. Sackellares JC, Shiau DS, Halford JJ, LaRoche SM, Kelly KM. Quantitative EEG analysis for automated detection of nonconvulsive seizures in intensive care units. Epilepsy Behav. 2011 Dec; 22 Suppl 1:S69-73. PMID: 22078521.
      Citations:    
    41. Bonilha L, Halford JJ, Morgan PS, Edwards JC. Hippocampal atrophy in temporal lobe epilepsy: the 'generator' and 'receiver'. Acta Neurol Scand. 2012 Feb; 125(2):105-10. PMID: 21470191.
      Citations:    
    42. Halford JJ, Pressly WB, Benbadis SR, Tatum WO, Turner RP, Arain A, Pritchard PB, Edwards JC, Dean BC. Web-based collection of expert opinion on routine scalp EEG: software development and interrater reliability. J Clin Neurophysiol. 2011 Apr; 28(2):178-84. PMID: 21399515.
      Citations:    
    43. Halford JJ, Ben-Menachem E, Kwan P, Ness S, Schmitt J, Eerdekens M, Novak G. A randomized, double-blind, placebo-controlled study of the efficacy, safety, and tolerability of adjunctive carisbamate treatment in patients with partial-onset seizures. Epilepsia. 2011 Apr; 52(4):816-25. PMID: 21320109.
      Citations:    
    44. Shiau DS, Halford JJ, Kelly KM, Kern RT, Inman M, Chien JH, Pardalos PM, Yang MC, Sackellares JC. SIGNAL REGULARITY-BASED AUTOMATED SEIZURE DETECTION SYSTEM FOR SCALP EEG MONITORING. Cybern Syst Anal. 2010 Nov 01; 46(6):922-935. PMID: 21188288.
      Citations:    
    45. Kelly KM, Shiau DS, Kern RT, Chien JH, Yang MC, Yandora KA, Valeriano JP, Halford JJ, Sackellares JC. Assessment of a scalp EEG-based automated seizure detection system. Clin Neurophysiol. 2010 Nov; 121(11):1832-43. PMID: 20471311.
      Citations:    
    46. Bonilha L, Edwards JC, Kinsman SL, Morgan PS, Fridriksson J, Rorden C, Rumboldt Z, Roberts DR, Eckert MA, Halford JJ. Extrahippocampal gray matter loss and hippocampal deafferentation in patients with temporal lobe epilepsy. Epilepsia. 2010 Apr; 51(4):519-28. PMID: 20163442.
      Citations:    
    47. Halford JJ, Shiau DS, Kern RT, Stroman CA, Kelly KM, Sackellares JC. Seizure Detection Software Used to Complement the Visual Screening Process for Long-Term EEG Monitoring. Am J Electroneurodiagnostic Technol. 2010; 50(2):133-147. PMID: 26658426.
      Citations:    
    48. Sperling MR, Greenspan A, Cramer JA, Kwan P, Kälviäinen R, Halford JJ, Schmitt J, Yuen E, Cook T, Haas M, Novak G. Carisbamate as adjunctive treatment of partial onset seizures in adults in two randomized, placebo-controlled trials. Epilepsia. 2010 Mar; 51(3):333-43. PMID: 19863578.
      Citations:    
    49. Halford JJ. Computerized epileptiform transient detection in the scalp electroencephalogram: obstacles to progress and the example of computerized ECG interpretation. Clin Neurophysiol. 2009 Nov; 120(11):1909-1915. PMID: 19836303.
      Citations:    
    50. Bonilha L, Halford JJ. Network atrophy in temporal lobe epilepsy: a voxel-based morphometry study. Neurology. 2009 Jun 09; 72(23):2052; author reply 2052. PMID: 19506231.
      Citations:    
    51. Halford JJ, Lapointe M. Clinical perspectives on lacosamide. Epilepsy Curr. 2009 Jan-Feb; 9(1):1-9. PMID: 19396339.
      Citations:    
    52. Bonilha L, Halford JJ, Rorden C, Roberts DR, Rumboldt Z, Eckert MA. Automated MRI analysis for identification of hippocampal atrophy in temporal lobe epilepsy. Epilepsia. 2009 Feb; 50(2):228-33. PMID: 18727679.
      Citations:    
    53. Bonilha L, Halford J, Rorden C, Li LM, Patel A, Rumbolt Z, Morgan P. Microstructural white matter abnormalities in nodular heterotopia with overlying polymicrogyria. Seizure. 2007 Jan; 16(1):74-80. PMID: 17097893.
      Citations:    
    54. Bonilha L, Rorden C, Halford JJ, Eckert M, Appenzeller S, Cendes F, Li LM. Asymmetrical extra-hippocampal grey matter loss related to hippocampal atrophy in patients with medial temporal lobe epilepsy. J Neurol Neurosurg Psychiatry. 2007 Mar; 78(3):286-94. PMID: 17012334.
      Citations:    
    55. Halford J, Mazeika G, Slifer S, Speer M, Saunders AM, Strittmatter WJ, Morgenlander JC. APOE2 allele increased in tardive dyskinesia. Mov Disord. 2006 Apr; 21(4):540-2. PMID: 16261623.
      Citations:    
    56. Halford JJ. Neurophysiologic correlates of psychiatric disorders and potential applications in epilepsy. Epilepsy Behav. 2003 Aug; 4(4):375-85. PMID: 12899857.
      Citations:    
    57. Dell DL, Halford JJ. Dementia presenting as postpartum depression. Obstet Gynecol. 2002 May; 99(5 Pt 2):925-8. PMID: 11975961.
      Citations:    
    Halford's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (172)
    Explore
    _
    Co-Authors (18)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _