Wayne R Fitzgibbon

Title
InstitutionMedical University of South Carolina
DepartmentNephrology
AddressP.O. Box MSC 629
Drug Discovery Building, 5th Floor
Drug Discovery Building - 70 President St.
Phone843-876-2271
Fax843-792-8399
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Polina I, Domondon M, Fox R, Sudarikova AV, Troncoso M, Vasileva VY, Kashyrina Y, Gooz MB, Schibalski RS, DeLeon-Pennell KY, Fitzgibbon WR, Ilatovskaya DV. Differential effects of low-dose sacubitril and/or valsartan on renal disease in salt-sensitive hypertension. Am J Physiol Renal Physiol. 2020 07 01; 319(1):F63-F75. PMID: 32463726.
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    2. Zimmerman KA, Huang J, He L, Revell DZ, Li Z, Hsu JS, Fitzgibbon WR, Hazard ES, Hardiman G, Mrug M, Bell PD, Yoder BK, Saigusa T. Interferon Regulatory Factor-5 in Resident Macrophage Promotes Polycystic Kidney Disease. Kidney360. 2020 Mar; 1(3):179-190. PMID: 33490963.
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    3. Arif E, Solanki AK, Srivastava P, Rahman B, Fitzgibbon WR, Deng P, Budisavljevic MN, Baicu CF, Zile MR, Megyesi J, Janech MG, Kwon SH, Collier J, Schnellmann RG, Nihalani D. Mitochondrial biogenesis induced by the ß2-adrenergic receptor agonist formoterol accelerates podocyte recovery from glomerular injury. Kidney Int. 2019 09; 96(3):656-673. PMID: 31262488.
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    4. Arif E, Solanki AK, Srivastava P, Rahman B, Tash BR, Holzman LB, Janech MG, Martin R, Knölker HJ, Fitzgibbon WR, Deng P, Budisavljevic MN, Syn WK, Wang C, Lipschutz JH, Kwon SH, Nihalani D. The motor protein Myo1c regulates transforming growth factor-ß-signaling and fibrosis in podocytes. Kidney Int. 2019 07; 96(1):139-158. PMID: 31097328.
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    5. Fitzgibbon WR, Dang Y, Bunni MA, Baicu CF, Zile MR, Mullick AE, Saigusa T. Attenuation of accelerated renal cystogenesis in Pkd1 mice by renin-angiotensin system blockade. Am J Physiol Renal Physiol. 2018 02 01; 314(2):F210-F218. PMID: 29021226.
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    6. Hakmei JE, Nietert PJ, Fitzgibbon WR, Ullian ME. Length of Interdialytic Intervals Affects Morbidity and Mortality in Chronic Haemodialysis Patients. J Clin Exp Nephrol. 2017; 2(2). PMID: 31528834.
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    7. Velez JCQ, Arif E, Rodgers J, Hicks MP, Arthur JM, Nihalani D, Bruner ET, Budisavljevic MN, Atkinson C, Fitzgibbon WR, Janech MG. Deficiency of the Angiotensinase Aminopeptidase A Increases Susceptibility to Glomerular Injury. J Am Soc Nephrol. 2017 Jul; 28(7):2119-2132. PMID: 28202497.
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    8. Saigusa T, Dang Y, Bunni MA, Amria MY, Steele SL, Fitzgibbon WR, Bell PD. Activation of the intrarenal renin-angiotensin-system in murine polycystic kidney disease. Physiol Rep. 2015 May; 3(5). PMID: 25999403.
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    9. Sas KM, Yin H, Fitzgibbon WR, Baicu CF, Zile MR, Steele SL, Amria M, Saigusa T, Funk J, Bunni MA, Siegal GP, Siroky BJ, Bissler JJ, Bell PD. Hyperglycemia in the absence of cilia accelerates cystogenesis and induces renal damage. Am J Physiol Renal Physiol. 2015 Jul 01; 309(1):F79-87. PMID: 25904703.
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    10. Wilson PC, Fitzgibbon WR, Garrett SM, Jaffa AA, Luttrell LM, Brands MW, El-Shewy HM. Inhibition of Sphingosine Kinase 1 Ameliorates Angiotensin II-Induced Hypertension and Inhibits Transmembrane Calcium Entry via Store-Operated Calcium Channel. Mol Endocrinol. 2015 Jun; 29(6):896-908. PMID: 25871850.
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    11. Velez JC, Janech MG, Hicks MP, Morinelli TA, Rodgers J, Self SE, Arthur JM, Fitzgibbon WR. Lack of renoprotective effect of chronic intravenous angiotensin-(1-7) or angiotensin-(2-10) in a rat model of focal segmental glomerulosclerosis. PLoS One. 2014; 9(10):e110083. PMID: 25337950.
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    12. Bell PD, Fitzgibbon W, Sas K, Stenbit AE, Amria M, Houston A, Reichert R, Gilley S, Siegal GP, Bissler J, Bilgen M, Chou PC, Guay-Woodford L, Yoder B, Haycraft CJ, Siroky B. Loss of primary cilia upregulates renal hypertrophic signaling and promotes cystogenesis. J Am Soc Nephrol. 2011 May; 22(5):839-48. PMID: 21493775.
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    13. Joseph AJ, Compton SP, Holmes LH, Annand A, Self SE, Fitzgibbon WR, Ullian ME. Utility of percutaneous renal biopsy in chronic kidney disease. Nephrology (Carlton). 2010 Aug; 15(5):544-8. PMID: 20649874.
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    14. Velez JC, Ryan KJ, Harbeson CE, Bland AM, Budisavljevic MN, Arthur JM, Fitzgibbon WR, Raymond JR, Janech MG. Angiotensin I is largely converted to angiotensin (1-7) and angiotensin (2-10) by isolated rat glomeruli. Hypertension. 2009 May; 53(5):790-7. PMID: 19289651.
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    15. Ullian ME, Beck CN, Walker LP, Fitzgibbon WR, Morinelli TA. Thiol antioxidants regulate angiotensin II AT1 and arginine vasopressin V1 receptor functions differently in vascular smooth muscle cells. Am J Hypertens. 2009 Feb; 22(2):221-7. PMID: 19039312.
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    16. Sivritas SH, Ploth DW, Fitzgibbon WR. Blockade of renal medullary bradykinin B2 receptors increases tubular sodium reabsorption in rats fed a normal-salt diet. Am J Physiol Renal Physiol. 2008 Sep; 295(3):F811-7. PMID: 18632797.
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    17. Janech MG, Fitzgibbon WR, Nowak MW, Miller DH, Paul RV, Ploth DW. Cloning and functional characterization of a second urea transporter from the kidney of the Atlantic stingray, Dasyatis sabina. . 2006 Sep; 291(3):R844-53. PMID: 16614049.
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    18. Janech MG, Fitzgibbon WR, Ploth DW, Lacy ER, Miller DH. Effect of low environmental salinity on plasma composition and renal function of the Atlantic stingray, a euryhaline elasmobranch. Am J Physiol Renal Physiol. 2006 Oct; 291(4):F770-80. PMID: 16609153.
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    19. Chen J, Batta A, Zheng S, Fitzgibbon WR, Ullian ME, Yu H, Tso P, Salen G, Patel SB. The missense mutation in Abcg5 gene in spontaneously hypertensive rats (SHR) segregates with phytosterolemia but not hypertension. BMC Genet. 2005 Jul 18; 6:40. PMID: 16026620.
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    20. Ullian ME, Gelasco AK, Fitzgibbon WR, Beck CN, Morinelli TA. N-acetylcysteine decreases angiotensin II receptor binding in vascular smooth muscle cells. J Am Soc Nephrol. 2005 Aug; 16(8):2346-53. PMID: 15944340.
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    21. Ullian ME, Gantt BJ, Ford AK, Tholanikunnel BG, Spicer EK, Fitzgibbon WR. Potential importance of glomerular citrate synthase activity in remnant nephropathy. Kidney Int. 2003 Jan; 63(1):156-64. PMID: 12472778.
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    22. Janech MG, Fitzgibbon WR, Chen R, Nowak MW, Miller DH, Paul RV, Ploth DW. Molecular and functional characterization of a urea transporter from the kidney of the Atlantic stingray. Am J Physiol Renal Physiol. 2003 May; 284(5):F996-F1005. PMID: 12388386.
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    23. Janech MG, Chen R, Klein J, Nowak MW, McFee W, Paul RV, Fitzgibbon WR, Ploth DW. Molecular and functional characterization of a urea transporter from the kidney of a short-finned pilot whale. . 2002 May; 282(5):R1490-500. PMID: 11959693.
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    24. Ullian ME, Robinson CJ, Evans CT, Melnick JZ, Fitzgibbon WR. Role of citrate synthase in aldosterone-mediated sodium reabsorption. Hypertension. 2000 Apr; 35(4):875-9. PMID: 10775554.
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    25. Fitzgibbon WR, Greene EL, Grewal JS, Hutchison FN, Self SE, Latten SY, Ullian ME. Resistance to remnant nephropathy in the Wistar-Furth rat. J Am Soc Nephrol. 1999 Apr; 10(4):814-21. PMID: 10203366.
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    26. Mukai H, Fitzgibbon WR, Ploth DW, Margolius HS. Effect of chronic bradykinin B2 receptor blockade on blood pressure of conscious Dahl salt-resistant rats. Br J Pharmacol. 1998 May; 124(1):197-205. PMID: 9630360.
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    27. Ullian ME, Islam MM, Robinson CJ, Fitzgibbon WR, Tobin ET, Paul RV. Resistance to mineralocorticoids in Wistar-Furth rats. Am J Physiol. 1997 Mar; 272(3 Pt 2):H1454-61. PMID: 9087624.
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    28. Mukai H, Fitzgibbon WR, Bozeman G, Margolius HS, Ploth DW. Bradykinin B2 receptor antagonist increases chloride and water absorption in rat medullary collecting duct. Am J Physiol. 1996 Aug; 271(2 Pt 2):R352-60. PMID: 8770134.
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    29. Fitzgibbon WR, Webster SK, Imamura A, Ploth DW, Hutchison FN. Effect of dietary protein and enalapril on proximal tubular delivery and absorption of albumin in nephrotic rats. Am J Physiol. 1996 Jun; 270(6 Pt 2):F986-96. PMID: 8764318.
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    30. Fitzgibbon WR, Jaffa AA, Mayfield RK, Ploth DW. Role of kinins in the renal response to enalaprilat in normotensive and hypertensive rats. Hypertension. 1996 Feb; 27(2):235-44. PMID: 8567046.
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    31. Imamura A, Mackenzie HS, Lacy ER, Hutchison FN, Fitzgibbon WR, Ploth DW. Effects of chronic treatment with angiotensin converting enzyme inhibitor or an angiotensin receptor antagonist in two-kidney, one-clip hypertensive rats. Kidney Int. 1995 May; 47(5):1394-402. PMID: 7637269.
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    32. Fitzgibbon WR, Ploth DW, Margolius HS. Kinins as vasoactive peptides. Curr Opin Nephrol Hypertens. 1993 Mar; 2(2):283-90. PMID: 7922188.
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    33. Saxenhofer H, Fitzgibbon WR, Paul RV. Urodilatin: binding properties and stimulation of cGMP generation in rat kidney cells. Am J Physiol. 1993 Feb; 264(2 Pt 2):F267-73. PMID: 8095370.
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