Sarah W. Book

Title
InstitutionMedical University of South Carolina
DepartmentPsychiatry and Behavioral Sciences
AddressP.O. Box MSC 861
458N
67 President St.
Phone843-792-5200
Fax843-792-7353
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    Dr Book's general interests are related to helping people with drug and alcohol problems that co-occur with depression and anxiety. As the Medical Director of our addictions treatment program, she is a member of an inter-professional team of Psychologists and Social Workers who all work together to help patients reach their goals. She also mentors medical students, psychiatry residents, and addiction psychiatry fellows, supervising them in their clinical work. Her research interests include finding effective medication interventions, as well as developing educational programs to teach trainees about helping people with drug and alcohol problems, and encouraging MD trainees to pursue careers that include research.
    Collapse keywords
    Alcohol dependence, anxiety, addiction treatment, developing educational programs

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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Anton RF, Voronin KE, Book SW, Latham PK, Randall PK, Glen WB, Hoffman M, Schacht JP. Opioid and Dopamine Genes Interact to Predict Naltrexone Response in a Randomized Alcohol Use Disorder Clinical Trial. Alcohol Clin Exp Res. 2020 10; 44(10):2084-2096. PMID: 32772383.
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    2. Anton RF, Latham P, Voronin K, Book S, Hoffman M, Prisciandaro J, Bristol E. Efficacy of Gabapentin for the Treatment of Alcohol Use Disorder in Patients With Alcohol Withdrawal Symptoms: A Randomized Clinical Trial. JAMA Intern Med. 2020 05 01; 180(5):728-736. PMID: 32150232.
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    3. Wilkerson AK, Sahlem GL, Bentzley BS, Lord J, Smith JP, Simmons RO, Uhde TW, Book SW. Insomnia severity during early abstinence is related to substance use treatment completion in adults enrolled in an intensive outpatient program. J Subst Abuse Treat. 2019 09; 104:97-103. PMID: 31370990.
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    4. Anton RF, Latham PK, Voronin KE, Randall PK, Book SW, Hoffman M, Schacht JP. Nicotine-Use/Smoking Is Associated with the Efficacy of Naltrexone in the Treatment of Alcohol Dependence. Alcohol Clin Exp Res. 2018 Apr; 42(4):751-760. PMID: 29431852.
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    5. Schacht JP, Randall PK, Latham PK, Voronin KE, Book SW, Myrick H, Anton RF. Predictors of Naltrexone Response in a Randomized Trial: Reward-Related Brain Activation, OPRM1 Genotype, and Smoking Status. Neuropsychopharmacology. 2017 12; 42(13):2654. PMID: 29123234.
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    6. Campbell ANC, Back SE, Ostroff JS, Hien DA, Gourevitch MN, Sheffer CE, Brady KT, Hanley K, Bereket S, Book S. Addiction Research Training Programs: Four Case Studies and Recommendations for Evaluation. J Addict Med. 2017 Sep/Oct; 11(5):333-338. PMID: 28590393.
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    7. Schacht JP, Randall PK, Latham PK, Voronin KE, Book SW, Myrick H, Anton RF. Predictors of Naltrexone Response in a Randomized Trial: Reward-Related Brain Activation, OPRM1 Genotype, and Smoking Status. Neuropsychopharmacology. 2017 Dec; 42(13):2640-2653. PMID: 28409564.
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    8. Bentzley BS, Barth KS, Back SE, Aronson G, Book SW. Patient Perspectives Associated with Intended Duration of Buprenorphine Maintenance Therapy. J Subst Abuse Treat. 2015 Sep; 56:48-53. PMID: 25899872.
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    9. Bentzley BS, Barth KS, Back SE, Book SW. Discontinuation of buprenorphine maintenance therapy: perspectives and outcomes. J Subst Abuse Treat. 2015 May; 52:48-57. PMID: 25601365.
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    10. Miller PM, Book SW, Thomas S, Smith JP, Randall PK, Randall CL. The potential utility of drinking motive questions to screen at-risk drinking in socially anxious patients. J Subst Use. 2014 Jun 01; 19(3):225-228. PMID: 24982593.
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    11. Cluver J, Book S, Brady K, Back S, Thornley N. Engaging medical students in research: reaching out to the next generation of physician-scientists. Acad Psychiatry. 2014 Jun; 38(3):345-9. PMID: 24913099.
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    12. Anton RF, Schacht JP, Book SW. Pharmacologic treatment of alcoholism. Handb Clin Neurol. 2014; 125:527-42. PMID: 25307594.
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    13. Book SW, Thomas SE, Smith JP, Randall PK, Kushner MG, Bernstein GA, Specker SM, Miller PM, Randall CL. Treating individuals with social anxiety disorder and at-risk drinking: phasing in a brief alcohol intervention following paroxetine. J Anxiety Disord. 2013 Mar; 27(2):252-8. PMID: 23523988.
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    14. Book SW, Thomas SE, Smith JP, Miller PM. Severity of anxiety in mental health versus addiction treatment settings when social anxiety and substance abuse are comorbid. Addict Behav. 2012 Oct; 37(10):1158-61. PMID: 22658305.
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    15. Book SW, Thomas SE, Stewart SH, Miller PM. Client attitudes toward alcohol use self-report. Subst Abus. 2012; 33(2):124-9. PMID: 22489584.
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    16. Miller PM, Book SW, Stewart SH. Medical treatment of alcohol dependence: a systematic review. Int J Psychiatry Med. 2011; 42(3):227-66. PMID: 22439295.
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    17. Back SE, Book SW, Santos AB, Brady KT. Training physician-scientists: a model for integrating research into psychiatric residency. Acad Psychiatry. 2011 Jan-Feb; 35(1):40-5. PMID: 21209406.
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    18. Tonigan JS, Book SW, Pagano ME, Randall PK, Smith JP, Randall CL. 12-Step Therapy and Women with and without Social Phobia: A Study of the Effectiveness of 12-Step Therapy to Facilitate AA Engagement. Alcohol Treat Q. 2010 Apr 01; 28(2):151-162. PMID: 21423569.
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    19. Madan A, Borckardt JJ, Connell A, Book SB, Campbell S, Gwynette MF, Wimberly LA, Wagner M, Weinstein B, McLeod-Bryant S, Cooney H, Herbert J. Routine assessment of patient-reported outcomes in behavioral health: room for improvement. Qual Manag Health Care. 2010 Jan-Mar; 19(1):70-81. PMID: 20042935.
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    20. Smith JP, Book SW. Comorbidity of generalized anxiety disorder and alcohol use disorders among individuals seeking outpatient substance abuse treatment. Addict Behav. 2010 Jan; 35(1):42-5. PMID: 19733441.
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    21. Book SW, Thomas SE, Dempsey JP, Randall PK, Randall CL. Social anxiety impacts willingness to participate in addiction treatment. Addict Behav. 2009 May; 34(5):474-6. PMID: 19195794.
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    22. Smith JP, Book SW. Anxiety and Substance Use Disorders: A Review. Psychiatr Times. 2008 Oct; 25(10):19-23. PMID: 20640182.
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    23. Dempsey JP, Randall PK, Thomas SE, Book SW, Carrigan MH. Treatment of social anxiety with paroxetine: mediation of changes in anxiety and depression symptoms. Compr Psychiatry. 2009 Mar-Apr; 50(2):135-41. PMID: 19216890.
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    24. Thomas SE, Miller PM, Randall PK, Book SW. Improving acceptance of naltrexone in community addiction treatment centers: a pilot study. J Subst Abuse Treat. 2008 Oct; 35(3):260-8. PMID: 18329227.
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    25. Thomas SE, Randall PK, Book SW, Randall CL. A complex relationship between co-occurring social anxiety and alcohol use disorders: what effect does treating social anxiety have on drinking? Alcohol Clin Exp Res. 2008 Jan; 32(1):77-84. PMID: 18028529.
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    26. Book SW, Myrick H, Malcolm R, Strain EC. Buprenorphine for postoperative pain following general surgery in a buprenorphine-maintained patient. Am J Psychiatry. 2007 Jun; 164(6):979. PMID: 17541066.
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    27. Book SW, Thomas SE, Randall PK, Randall CL. Paroxetine reduces social anxiety in individuals with a co-occurring alcohol use disorder. J Anxiety Disord. 2008; 22(2):310-8. PMID: 17448631.
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    28. Book SW, Myrick H. Novel anticonvulsants in the treatment of alcoholism. Expert Opin Investig Drugs. 2005 Apr; 14(4):371-6. PMID: 15882114.
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    29. Malcolm R, Book SW, Moak D, DeVane L, Czepowicz V. Clinical applications of modafinil in stimulant abusers: low abuse potential. Am J Addict. 2002; 11(3):247-9. PMID: 12202017.
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    30. Emmanuel NP, Brawman-Mintzer O, Morton WA, Book SW, Johnson MR, Lorberbaum JP, Ballenger JC, Lydiard RB. Bupropion-SR in treatment of social phobia. Depress Anxiety. 2000; 12(2):111-3. PMID: 11091936.
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    31. Lorberbaum JP, Newman JD, Dubno JR, Horwitz AR, Nahas Z, Teneback CC, Bloomer CW, Bohning DE, Vincent D, Johnson MR, Emmanuel N, Brawman-Mintzer O, Book SW, Lydiard RB, Ballenger JC, George MS. Feasibility of using fMRI to study mothers responding to infant cries. Depress Anxiety. 1999; 10(3):99-104. PMID: 10604082.
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    32. Connor KM, Davidson JR, Potts NL, Tupler LA, Miner CM, Malik ML, Book SW, Colket JT, Ferrell F. Discontinuation of clonazepam in the treatment of social phobia. J Clin Psychopharmacol. 1998 Oct; 18(5):373-8. PMID: 9790154.
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    33. Davidson JR, Book SW, Colket JT, Tupler LA, Roth S, David D, Hertzberg M, Mellman T, Beckham JC, Smith RD, Davison RM, Katz R, Feldman ME. Assessment of a new self-rating scale for post-traumatic stress disorder. Psychol Med. 1997 Jan; 27(1):153-60. PMID: 9122295.
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    34. Potts NL, Book S, Davidson JR. The neurobiology of social phobia. Int Clin Psychopharmacol. 1996 Jun; 11 Suppl 3:43-8. PMID: 8923109.
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    35. Muly EC, McDonald W, Steffens D, Book S. Serotonin syndrome produced by a combination of fluoxetine and lithium. Am J Psychiatry. 1993 Oct; 150(10):1565. PMID: 8379573.
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