 Receptors, sigma
"Receptors, sigma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of cell surface receptors recognized by its pharmacological profile. Sigma receptors were originally considered to be opioid receptors because they bind certain synthetic opioids. However they also interact with a variety of other psychoactive drugs, and their endogenous ligand is not known (although they can react to certain endogenous steroids). Sigma receptors are found in the immune, endocrine, and nervous systems, and in some peripheral tissues.
| Descriptor ID |
D017480
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| MeSH Number(s) |
D12.776.543.750.100.620.775 D12.776.543.750.720.600.610.775 D12.776.543.750.750.555.610.775
|
| Concept/Terms |
Receptors, sigma- Receptors, sigma
- sigma Receptors
- Receptors, sigma Opioid
- Opioid Receptors, sigma
- sigma Opioid Receptors
- Receptors, Opioid, sigma
- sigma Receptor
- Receptor, sigma
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Below are MeSH descriptors whose meaning is more general than "Receptors, sigma".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Opioid [D12.776.543.750.100.620]
- Receptors, sigma [D12.776.543.750.100.620.775]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Opioid [D12.776.543.750.720.600.610]
- Receptors, sigma [D12.776.543.750.720.600.610.775]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Opioid [D12.776.543.750.750.555.610]
- Receptors, sigma [D12.776.543.750.750.555.610.775]
Below are MeSH descriptors whose meaning is more specific than "Receptors, sigma".
This graph shows the total number of publications written about "Receptors, sigma" by people in this website by year, and whether "Receptors, sigma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, sigma" by people in Profiles.
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Hedges DM, Obray JD, Yorgason JT, Jang EY, Weerasekara VK, Uys JD, Bellinger FP, Steffensen SC. Methamphetamine Induces Dopamine Release in the Nucleus Accumbens Through a Sigma Receptor-Mediated Pathway. Neuropsychopharmacology. 2018 05; 43(6):1405-1414.
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He H, Cattran AW, Nguyen T, Nieminen AL, Xu P. Triple-responsive expansile nanogel for tumor and mitochondria targeted photosensitizer delivery. Biomaterials. 2014 Nov; 35(35):9546-53.
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Wu H, Li J, Fronczek FR, Ferreira D, Burandt CL, Setola V, Roth BL, Zjawiony JK. Labdane diterpenoids from Leonotis leonurus. Phytochemistry. 2013 Jul; 91:229-35.
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Yeomans DC, Jones T, Laurito CE, Lu Y, Wilson SP. Reversal of ongoing thermal hyperalgesia in mice by a recombinant herpesvirus that encodes human preproenkephalin. Mol Ther. 2004 Jan; 9(1):24-9.
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