"Glutamyl Aminopeptidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ZINC-dependent membrane-bound aminopeptidase that catalyzes the N-terminal peptide cleavage of GLUTAMATE (and to a lesser extent ASPARTATE). The enzyme appears to play a role in the catabolic pathway of the RENIN-ANGIOTENSIN SYSTEM.
Descriptor ID |
D043384
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MeSH Number(s) |
D08.811.277.656.350.100.373 D08.811.277.656.350.555.600 D08.811.277.656.675.555.600
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Concept/Terms |
Glutamyl Aminopeptidase- Glutamyl Aminopeptidase
- Aminopeptidase, Glutamyl
- Aspartyl Aminopeptidase
- Aminopeptidase, Aspartyl
- Aspartate Aminopeptidase
- Aminopeptidase, Aspartate
- Aminopeptidase A
- Angiotensinase A
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Below are MeSH descriptors whose meaning is more general than "Glutamyl Aminopeptidase".
Below are MeSH descriptors whose meaning is more specific than "Glutamyl Aminopeptidase".
This graph shows the total number of publications written about "Glutamyl Aminopeptidase" by people in this website by year, and whether "Glutamyl Aminopeptidase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2007 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glutamyl Aminopeptidase" by people in Profiles.
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Velez JCQ, Arif E, Rodgers J, Hicks MP, Arthur JM, Nihalani D, Bruner ET, Budisavljevic MN, Atkinson C, Fitzgibbon WR, Janech MG. Deficiency of the Angiotensinase Aminopeptidase A Increases Susceptibility to Glomerular Injury. J Am Soc Nephrol. 2017 Jul; 28(7):2119-2132.
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Schwacke JH, Spainhour JC, Ierardi JL, Chaves JM, Arthur JM, Janech MG, Velez JC. Network modeling reveals steps in angiotensin peptide processing. Hypertension. 2013 Mar; 61(3):690-700.
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Velez JC, Ryan KJ, Harbeson CE, Bland AM, Budisavljevic MN, Arthur JM, Fitzgibbon WR, Raymond JR, Janech MG. Angiotensin I is largely converted to angiotensin (1-7) and angiotensin (2-10) by isolated rat glomeruli. Hypertension. 2009 May; 53(5):790-7.
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Velez JC, Bland AM, Arthur JM, Raymond JR, Janech MG. Characterization of renin-angiotensin system enzyme activities in cultured mouse podocytes. Am J Physiol Renal Physiol. 2007 Jul; 293(1):F398-407.