Receptors, Antigen, B-Cell
"Receptors, Antigen, B-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
IMMUNOGLOBULINS on the surface of B-LYMPHOCYTES. Their MESSENGER RNA contains an EXON with a membrane spanning sequence, producing immunoglobulins in the form of type I transmembrane proteins as opposed to secreted immunoglobulins (ANTIBODIES) which do not contain the membrane spanning segment.
| Descriptor ID |
D011947
|
| MeSH Number(s) |
D12.776.124.790.651.950 D12.776.377.715.548.950 D12.776.543.750.705.816.821
|
| Concept/Terms |
Receptors, Antigen, B-Cell- Receptors, Antigen, B-Cell
- Membrane Bound Immunoglobulin
- Bound Immunoglobulin, Membrane
- Immunoglobulin, Membrane Bound
- Membrane-Bound Immunoglobulins
- Membrane Bound Immunoglobulins
- B-Cell Antigen Receptors
- B Cell Antigen Receptors
- Immunoglobulins, Surface
- Receptors, Antigen, B Cell
- Antigen Receptors, B-Cell
- Antigen Receptors, B Cell
- Receptors, B-Cell Antigen
- Immunoglobulins, Membrane-Bound
- Immunoglobulins, Membrane Bound
- Surface Immunoglobulins
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Antigen, B-Cell".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Blood Proteins [D12.776.124]
- Serum Globulins [D12.776.124.790]
- Immunoglobulins [D12.776.124.790.651]
- Receptors, Antigen, B-Cell [D12.776.124.790.651.950]
- Globulins [D12.776.377]
- Serum Globulins [D12.776.377.715]
- Immunoglobulins [D12.776.377.715.548]
- Receptors, Antigen, B-Cell [D12.776.377.715.548.950]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Antigen [D12.776.543.750.705.816]
- Receptors, Antigen, B-Cell [D12.776.543.750.705.816.821]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Antigen, B-Cell".
This graph shows the total number of publications written about "Receptors, Antigen, B-Cell" by people in this website by year, and whether "Receptors, Antigen, B-Cell" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 4 | 0 | 4 |
| 1993 | 1 | 0 | 1 |
| 1994 | 4 | 1 | 5 |
| 1995 | 1 | 1 | 2 |
| 1996 | 4 | 0 | 4 |
| 1997 | 0 | 1 | 1 |
| 1998 | 2 | 1 | 3 |
| 1999 | 4 | 0 | 4 |
| 2000 | 2 | 0 | 2 |
| 2001 | 3 | 1 | 4 |
| 2002 | 5 | 0 | 5 |
| 2003 | 2 | 0 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 3 | 4 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, Antigen, B-Cell" by people in Profiles.
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Bolger-Munro M, Choi K, Scurll JM, Abraham L, Chappell RS, Sheen D, Dang-Lawson M, Wu X, Priatel JJ, Coombs D, Hammer JA, Gold MR. Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation. Elife. 2019 06 03; 8.
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Gold MR, Reth MG. Antigen Receptor Function in the Context of the Nanoscale Organization of the B Cell Membrane. Annu Rev Immunol. 2019 04 26; 37:97-123.
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Wang JC, Bolger-Munro M, Gold MR. Imaging the Interactions Between B Cells and Antigen-Presenting Cells. Methods Mol Biol. 2018; 1707:131-161.
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Abraham L, Lu HY, Falcão RC, Scurll J, Jou T, Irwin B, Tafteh R, Gold MR, Coombs D. Limitations of Qdot labelling compared to directly-conjugated probes for single particle tracking of B cell receptor mobility. Sci Rep. 2017 09 12; 7(1):11379.
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Wang JC, Lee JY, Christian S, Dang-Lawson M, Pritchard C, Freeman SA, Gold MR. The Rap1-cofilin-1 pathway coordinates actin reorganization and MTOC polarization at the B cell immune synapse. J Cell Sci. 2017 03 15; 130(6):1094-1109.
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Reth M, Gold MR. What goes up must come down: A tripartite Dok-3/Grb2/SHIP1 inhibitory module limits BCR signaling. Eur J Immunol. 2016 11; 46(11):2507-2511.
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Freeman SA, Jaumouillé V, Choi K, Hsu BE, Wong HS, Abraham L, Graves ML, Coombs D, Roskelley CD, Das R, Grinstein S, Gold MR. Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor. Nat Commun. 2015 Feb 03; 6:6168.
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Puri KD, Di Paolo JA, Gold MR. B-cell receptor signaling inhibitors for treatment of autoimmune inflammatory diseases and B-cell malignancies. Int Rev Immunol. 2013 Aug; 32(4):397-427.
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Freeman SA, Lei V, Dang-Lawson M, Mizuno K, Roskelley CD, Gold MR. Cofilin-mediated F-actin severing is regulated by the Rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation. J Immunol. 2011 Dec 01; 187(11):5887-900.
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Bradshaw S, Zheng WJ, Tsoi LC, Gilkeson G, Zhang XK. A role for Fli-1 in B cell proliferation: implications for SLE pathogenesis. Clin Immunol. 2008 Oct; 129(1):19-30.