"Gentamicins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
| Descriptor ID |
D005839
|
| MeSH Number(s) |
D09.408.051.374
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Gentamicins".
Below are MeSH descriptors whose meaning is more specific than "Gentamicins".
This graph shows the total number of publications written about "Gentamicins" by people in this website by year, and whether "Gentamicins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 |
| 1993 | 3 | 3 | 6 |
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1996 | 3 | 1 | 4 |
| 1997 | 1 | 0 | 1 |
| 1998 | 2 | 0 | 2 |
| 1999 | 2 | 0 | 2 |
| 2000 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 1 | 2 | 3 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Gentamicins" by people in Profiles.
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Lewin JJ, Cook AM, Gonzales C, Merola D, Neyens R, Peppard WJ, Brophy GM, Kurczewski L, Giarratano M, Makii J, Rowe AS, Tesoro EP, Zaniewski A, Clark S, Ziai WC. Current Practices of Intraventricular Antibiotic Therapy in the Treatment of Meningitis and Ventriculitis: Results from a Multicenter Retrospective Cohort Study. Neurocrit Care. 2019 06; 30(3):609-616.
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de Araújo NC, Bury PDS, Tavares MT, Huang F, Parise-Filho R, Leadlay P, Dias MVB. Crystal Structure of GenD2, an NAD-Dependent Oxidoreductase Involved in the Biosynthesis of Gentamicin. ACS Chem Biol. 2019 05 17; 14(5):925-933.
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Bury PDS, Huang F, Li S, Sun Y, Leadlay PF, Dias MVB. Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis. ACS Chem Biol. 2017 11 17; 12(11):2779-2787.
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Ficklin MG, Kunkel KA, Suber JT, Gerard PD, Kowaleski MP. Biomechanical evaluation of polymethyl methacrylate with the addition of various doses of cefazolin, vancomycin, gentamicin, and silver microparticles. Vet Comp Orthop Traumatol. 2016 Sep 20; 29(5):394-401.
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Ereshefsky BJ, Al-Hasan MN, Gokun Y, Martin CA. Comparison of ß-lactam plus aminoglycoside versus ß-lactam plus fluoroquinolone empirical therapy in serious nosocomial infections due to Gram-negative bacilli. J Chemother. 2017 Feb; 29(1):30-37.
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Genovese EA, Avgerinos ED, Baril DT, Makaroun MS, Chaer RA. Bio-absorbable antibiotic impregnated beads for the treatment of prosthetic vascular graft infections. Vascular. 2016 Dec; 24(6):590-597.
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Chen FQ, Zheng HW, Schacht J, Sha SH. Mitochondrial peroxiredoxin 3 regulates sensory cell survival in the cochlea. PLoS One. 2013; 8(4):e61999.
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Chen FQ, Hill K, Guan YJ, Schacht J, Sha SH. Activation of apoptotic pathways in the absence of cell death in an inner-ear immortomouse cell line. Hear Res. 2012 Feb; 284(1-2):33-41.
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Bennett-Guerrero E, Pappas TN, Koltun WA, Fleshman JW, Lin M, Garg J, Mark DB, Marcet JE, Remzi FH, George VV, Newland K, Corey GR. Gentamicin-collagen sponge for infection prophylaxis in colorectal surgery. N Engl J Med. 2010 Sep 09; 363(11):1038-49.
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Beeson CC, Beeson GC, Schnellmann RG. A high-throughput respirometric assay for mitochondrial biogenesis and toxicity. Anal Biochem. 2010 Sep 01; 404(1):75-81.