Th1 Cells

"Th1 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subset of helper-inducer T-lymphocytes which synthesize and secrete INTERLEUKIN-2; INTERFERON-GAMMA; and INTERLEUKIN-12. Due to their ability to kill antigen-presenting cells and their lymphokine-mediated effector activity, Th1 cells are associated with vigorous delayed-type hypersensitivity reactions.

Descriptor ID	D018417
MeSH Number(s)	A11.118.637.555.567.550.500.400.900 A11.118.637.555.567.569.200.400.900 A11.118.637.555.567.569.500.400.900 A15.145.229.637.555.567.550.500.400.500 A15.145.229.637.555.567.569.200.400.500 A15.145.229.637.555.567.569.500.400.500 A15.382.490.555.567.550.500.400.900 A15.382.490.555.567.569.200.400.900 A15.382.490.555.567.569.500.400.900
Concept/Terms	Th1 Cells Th1 Cells Cell, Th1 Cells, Th1 Th1 Cell TH-1 Cells Cell, TH-1 Cells, TH-1 TH 1 Cells TH-1 Cell T Helper 1 Cells Type 1 Helper T Cells

Below are MeSH descriptors whose meaning is more general than "Th1 Cells".

Anatomy [A]
Cells [A11]
Blood Cells [A11.118]
Leukocytes [A11.118.637]
Leukocytes, Mononuclear [A11.118.637.555]
Lymphocytes [A11.118.637.555.567]
Lymphocyte Subsets [A11.118.637.555.567.550]
T-Lymphocyte Subsets [A11.118.637.555.567.550.500]
T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.550.500.400]
Th1 Cells [A11.118.637.555.567.550.500.400.900]
T-Lymphocytes [A11.118.637.555.567.569]
CD4-Positive T-Lymphocytes [A11.118.637.555.567.569.200]
T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.200.400]
Th1 Cells [A11.118.637.555.567.569.200.400.900]
T-Lymphocyte Subsets [A11.118.637.555.567.569.500]
T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.500.400]
Th1 Cells [A11.118.637.555.567.569.500.400.900]
Hemic and Immune Systems [A15]
Blood [A15.145]
Blood Cells [A15.145.229]
Leukocytes [A15.145.229.637]
Leukocytes, Mononuclear [A15.145.229.637.555]
Lymphocytes [A15.145.229.637.555.567]
Lymphocyte Subsets [A15.145.229.637.555.567.550]
T-Lymphocyte Subsets [A15.145.229.637.555.567.550.500]
T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.550.500.400]
Th1 Cells [A15.145.229.637.555.567.550.500.400.500]
T-Lymphocytes [A15.145.229.637.555.567.569]
CD4-Positive T-Lymphocytes [A15.145.229.637.555.567.569.200]
T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.200.400]
Th1 Cells [A15.145.229.637.555.567.569.200.400.500]
T-Lymphocyte Subsets [A15.145.229.637.555.567.569.500]
T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.500.400]
Th1 Cells [A15.145.229.637.555.567.569.500.400.500]
Immune System [A15.382]
Leukocytes [A15.382.490]
Leukocytes, Mononuclear [A15.382.490.555]
Lymphocytes [A15.382.490.555.567]
Lymphocyte Subsets [A15.382.490.555.567.550]
T-Lymphocyte Subsets [A15.382.490.555.567.550.500]
T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.550.500.400]
Th1 Cells [A15.382.490.555.567.550.500.400.900]
T-Lymphocytes [A15.382.490.555.567.569]
CD4-Positive T-Lymphocytes [A15.382.490.555.567.569.200]
T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.200.400]
Th1 Cells [A15.382.490.555.567.569.200.400.900]
T-Lymphocyte Subsets [A15.382.490.555.567.569.500]
T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.500.400]
Th1 Cells [A15.382.490.555.567.569.500.400.900]

Below are MeSH descriptors whose meaning is related to "Th1 Cells".

Below are MeSH descriptors whose meaning is more specific than "Th1 Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Th1 Cells" by people in this website by year, and whether "Th1 Cells" was a major or minor topic of these publications.

Bar chart showing 53 publications over 20 distinct years, with a maximum of 6 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	1	1	2
1999	0	1	1
2002	1	2	3
2003	0	2	2
2004	1	2	3
2005	1	2	3
2006	1	2	3
2007	1	2	3
2008	1	1	2
2009	2	4	6
2010	0	3	3
2011	3	1	4
2012	2	0	2
2014	2	0	2
2015	0	1	1
2016	2	3	5
2017	0	1	1
2018	3	2	5
2019	1	0	1

Below are the most recent publications written about "Th1 Cells" by people in Profiles.

Miranda K, Mehrpouya-Bahrami P, Nagarkatti PS, Nagarkatti M. Cannabinoid Receptor 1 Blockade Attenuates Obesity and Adipose Tissue Type 1 Inflammation Through miR-30e-5p Regulation of Delta-Like-4 in Macrophages and Consequently Downregulation of Th1 Cells. Front Immunol. 2019; 10:1049.

View in: PubMed
Nguyen H, Kuril S, Bastian D, Kim J, Zhang M, Vaena SG, Dany M, Dai M, Heinrichs JL, Daenthanasanmak A, Iamsawat S, Schutt S, Fu J, Wu Y, Fairlie DP, Atkinson C, Ogretmen B, Tomlinson S, Yu XZ. Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells. JCI Insight. 2018 12 20; 3(24).

View in: PubMed
Carrell RK, Stanton RA, Ethier SP, LaRue AC, Soloff AC. ICOSL-augmented adenoviral-based vaccination induces a bipolar Th17/Th1 T cell response against unglycosylated MUC1 antigen. Vaccine. 2018 10 08; 36(42):6262-6269.

View in: PubMed
Singh I, Nath N, Saxena N, Singh AK, Won JS. Regulation of IL-10 and IL-17 mediated experimental autoimmune encephalomyelitis by S-nitrosoglutathione. Immunobiology. 2018 10; 223(10):549-554.

View in: PubMed
Saxena N, Won J, Choi S, Singh AK, Singh I. S-nitrosoglutathione reductase (GSNOR) inhibitor as an immune modulator in experimental autoimmune encephalomyelitis. Free Radic Biol Med. 2018 06; 121:57-68.

View in: PubMed
Wu Y, Schutt S, Paz K, Zhang M, Flynn RP, Bastian D, Sofi MH, Nguyen H, Dai M, Liu C, Chang YJ, Blazar BR, Yu XZ. MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice. Blood. 2018 04 26; 131(17):1974-1986.

View in: PubMed
Chatterjee S, Daenthanasanmak A, Chakraborty P, Wyatt MW, Dhar P, Selvam SP, Fu J, Zhang J, Nguyen H, Kang I, Toth K, Al-Homrani M, Husain M, Beeson G, Ball L, Helke K, Husain S, Garrett-Mayer E, Hardiman G, Mehrotra M, Nishimura MI, Beeson CC, Bupp MG, Wu J, Ogretmen B, Paulos CM, Rathmell J, Yu XZ, Mehrotra S. CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response. Cell Metab. 2018 01 09; 27(1):85-100.e8.

View in: PubMed
Mace TA, Shakya R, Pitarresi JR, Swanson B, McQuinn CW, Loftus S, Nordquist E, Cruz-Monserrate Z, Yu L, Young G, Zhong X, Zimmers TA, Ostrowski MC, Ludwig T, Bloomston M, Bekaii-Saab T, Lesinski GB. IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer. Gut. 2018 02; 67(2):320-332.

View in: PubMed
Podbielska M, Das A, Smith AW, Chauhan A, Ray SK, Inoue J, Azuma M, Nozaki K, Hogan EL, Banik NL. Neuron-microglia interaction induced bi-directional cytotoxicity associated with calpain activation. J Neurochem. 2016 11; 139(3):440-455.

View in: PubMed
Gattoni-Celli S, Young MR. Restoration of Immune Responsiveness to Glioma by Vaccination of Mice with Established Brain Gliomas with a Semi-Allogeneic Vaccine. Int J Mol Sci. 2016 Sep 02; 17(9).

View in: PubMed

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