Shahid Husain

Title
InstitutionMedical University of South Carolina
DepartmentOphthalmology
AddressP.O. Box MSC 676
713
Storm Eye Institute - 167 Ashley Ave.
Phone843-792-2792
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Solanki AK, Biswal MR, Walterhouse S, Martin R, Kondkar AA, Knölker HJ, Rahman B, Arif E, Husain S, Montezuma SR, Nihalani D, Lobo GP. Loss of Motor Protein MYO1C Causes Rhodopsin Mislocalization and Results in Impaired Visual Function. Cells. 2021 May 26; 10(6). PMID: 34073294.
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    2. Husain S, Zaidi SAH, Singh S, Guzman W, Mehrotra S. Reduction of Neuroinflammation by d-Opioids Via STAT3-Dependent Pathway in Chronic Glaucoma Model. Front Pharmacol. 2021; 12:601404. PMID: 33628191.
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    3. Zaidi SAH, Guzman W, Singh S, Mehrotra S, Husain S. Changes in Class I and IIb HDACs by d-Opioid in Chronic Rat Glaucoma Model. Invest Ophthalmol Vis Sci. 2020 12 01; 61(14):4. PMID: 33263714.
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    4. Zaidi SAH, Thakore N, Singh S, Guzman W, Mehrotra S, Gangaraju V, Husain S. Histone Deacetylases Regulation by d-Opioids in Human Optic Nerve Head Astrocytes. Invest Ophthalmol Vis Sci. 2020 09 01; 61(11):17. PMID: 32915982.
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    5. Chakraborty P, Vaena SG, Thyagarajan K, Chatterjee S, Al-Khami A, Selvam SP, Nguyen H, Kang I, Wyatt MW, Baliga U, Hedley Z, Ngang RN, Guo B, Beeson GC, Husain S, Paulos CM, Beeson CC, Zilliox MJ, Hill EG, Mehrotra M, Yu XZ, Ogretmen B, Mehrotra S. Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity. Cell Rep. 2019 08 13; 28(7):1879-1893.e7. PMID: 31412253.
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    6. Husain S. Delta Opioids: Neuroprotective Roles in Preclinical Studies. J Ocul Pharmacol Ther. 2018 Jan/Feb; 34(1-2):119-128. PMID: 29451852.
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    7. Husain S, Ahmad A, Singh S, Peterseim C, Abdul Y, Nutaitis MJ. PI3K/Akt Pathway: A Role in d-Opioid Receptor-Mediated RGC Neuroprotection. Invest Ophthalmol Vis Sci. 2017 12 01; 58(14):6489-6499. PMID: 29288267.
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    8. Chatterjee S, Daenthanasanmak A, Chakraborty P, Wyatt MW, Dhar P, Selvam SP, Fu J, Zhang J, Nguyen H, Kang I, Toth K, Al-Homrani M, Husain M, Beeson G, Ball L, Helke K, Husain S, Garrett-Mayer E, Hardiman G, Mehrotra M, Nishimura MI, Beeson CC, Bupp MG, Wu J, Ogretmen B, Paulos CM, Rathmell J, Yu XZ, Mehrotra S. CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response. Cell Metab. 2018 01 09; 27(1):85-100.e8. PMID: 29129787.
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    9. Lancina MG, Singh S, Kompella UB, Husain S, Yang H. Fast Dissolving Dendrimer Nanofiber Mats as Alternative to Eye Drops for More Efficient Antiglaucoma Drug Delivery. ACS Biomater Sci Eng. 2017 Aug 14; 3(8):1861-1868. PMID: 29152562.
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    10. Kesarwani P, Chakraborty P, Gudi R, Chatterjee S, Scurti G, Toth K, Simms P, Husain M, Armeson K, Husain S, Garrett-Mayer E, Vasu C, Nishimura MI, Mehrotra S. Blocking TCR restimulation induced necroptosis in adoptively transferred T cells improves tumor control. Oncotarget. 2016 Oct 25; 7(43):69371-69383. PMID: 27750220.
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    11. Husain S. Opioid receptors: methods for detection and their modes of actions in the eye. Methods Mol Biol. 2015; 1230:243-51. PMID: 25293331.
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    12. Husain S, Abdul Y, Singh S, Ahmad A, Husain M. Regulation of nitric oxide production by d-opioid receptors during glaucomatous injury. PLoS One. 2014; 9(10):e110397. PMID: 25329670.
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    13. Kesarwani P, Al-Khami AA, Scurti G, Thyagarajan K, Kaur N, Husain S, Fang Q, Naga OS, Simms P, Beeson G, Voelkel-Johnson C, Garrett-Mayer E, Beeson CC, Nishimura MI, Mehrotra S. Promoting thiol expression increases the durability of antitumor T-cell functions. Cancer Res. 2014 Nov 01; 74(21):6036-6047. PMID: 25164014.
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    14. Sharif NA, Katoli P, Scott D, Li L, Kelly C, Xu S, Husain S, Toris C, Crosson C. FR-190997, a nonpeptide bradykinin B2-receptor partial agonist, is a potent and efficacious intraocular pressure lowering agent in ocular hypertensive cynomolgus monkeys. Drug Dev Res. 2014 Jun; 75(4):211-23. PMID: 24796320.
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    15. Husain S, Abdul Y, Webster C, Chatterjee S, Kesarwani P, Mehrotra S. Interferon-gamma (IFN-?)-mediated retinal ganglion cell death in human tyrosinase T cell receptor transgenic mouse. PLoS One. 2014; 9(2):e89392. PMID: 24586745.
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    16. Akhter N, Nix M, Abdul Y, Singh S, Husain S. Delta-opioid receptors attenuate TNF-a-induced MMP-2 secretion from human ONH astrocytes. Invest Ophthalmol Vis Sci. 2013 Oct 09; 54(10):6605-11. PMID: 24030463.
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    17. Sharif NA, Xu S, Li L, Katoli P, Kelly CR, Wang Y, Cao S, Patil R, Husain S, Klekar L, Scott D. Protein expression, biochemical pharmacology of signal transduction, and relation to intraocular pressure modulation by bradykinin B2 receptors in ciliary muscle. Mol Vis. 2013; 19:1356-70. PMID: 23805043.
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    18. Abdul Y, Akhter N, Husain S. Delta-opioid agonist SNC-121 protects retinal ganglion cell function in a chronic ocular hypertensive rat model. Invest Ophthalmol Vis Sci. 2013 Mar 11; 54(3):1816-28. PMID: 23404122.
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    19. Mehrotra S, Al-Khami AA, Klarquist J, Husain S, Naga O, Eby JM, Murali AK, Lyons GE, Li M, Spivey ND, Norell H, Martins da Palma T, Onicescu G, Diaz-Montero CM, Garrett-Mayer E, Cole DJ, Le Poole IC, Nishimura MI. A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice. J Immunol. 2012 Aug 15; 189(4):1627-38. PMID: 22798675.
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    20. Husain S, Abdul Y, Crosson CE. Preservation of retina ganglion cell function by morphine in a chronic ocular-hypertensive rat model. Invest Ophthalmol Vis Sci. 2012 Jun 28; 53(7):4289-98. PMID: 22661469.
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    21. Husain S, Abdul Y, Potter DE. Non-analgesic effects of opioids: neuroprotection in the retina. Curr Pharm Des. 2012; 18(37):6101-8. PMID: 22747547.
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    22. Husain S, Liou GI, Crosson CE. Opioid receptor activation: suppression of ischemia/reperfusion-induced production of TNF-a in the retina. Invest Ophthalmol Vis Sci. 2011 Apr; 52(5):2577-83. PMID: 21282567.
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    23. Crosson CE, Mani SK, Husain S, Alsarraf O, Menick DR. Inhibition of histone deacetylase protects the retina from ischemic injury. Invest Ophthalmol Vis Sci. 2010 Jul; 51(7):3639-45. PMID: 20164449.
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    24. Husain S, Potter DE, Crosson CE. Opioid receptor-activation: retina protected from ischemic injury. Invest Ophthalmol Vis Sci. 2009 Aug; 50(8):3853-9. PMID: 19324855.
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    25. Sharif NA, McLaughlin MA, Kelly CR, Katoli P, Drace C, Husain S, Crosson C, Toris C, Zhan GL, Camras C. Cabergoline: Pharmacology, ocular hypotensive studies in multiple species, and aqueous humor dynamic modulation in the Cynomolgus monkey eyes. Exp Eye Res. 2009 Mar; 88(3):386-97. PMID: 18992242.
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    26. Husain S, Yates PW, Crosson CE. Latanoprost-induced changes in rat intraocular pressure: direct or indirect? J Ocul Pharmacol Ther. 2008 Aug; 24(4):367-72. PMID: 18665807.
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    27. Husain S, Crosson CE. Role of PKCepsilon in PGF2alpha-stimulated MMP-2 secretion from human ciliary muscle cells. J Ocul Pharmacol Ther. 2008 Jun; 24(3):268-77. PMID: 18462068.
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    28. Husain S, Potter DE. The opioidergic system: potential roles and therapeutic indications in the eye. J Ocul Pharmacol Ther. 2008 Apr; 24(2):117-40. PMID: 18355128.
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    29. Wingard C, Fulton D, Husain S. Altered penile vascular reactivity and erection in the Zucker obese-diabetic rat. J Sex Med. 2007 Mar; 4(2):348-62; discussion 362-3. PMID: 17367430.
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    30. Husain S, Whitlock NA, Rice DS, Crosson CE. Effects of latanoprost on rodent intraocular pressure. Exp Eye Res. 2006 Dec; 83(6):1453-8. PMID: 17027754.
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    31. Husain S, Shearer TW, Crosson CE. Mechanisms linking adenosine A1 receptors and extracellular signal-regulated kinase 1/2 activation in human trabecular meshwork cells. J Pharmacol Exp Ther. 2007 Jan; 320(1):258-65. PMID: 17015637.
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    32. Webb JG, Husain S, Yates PW, Crosson CE. Kinin modulation of conventional outflow facility in the bovine eye. J Ocul Pharmacol Ther. 2006 Oct; 22(5):310-6. PMID: 17076624.
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    33. Husain S, Jafri F, Crosson CE. Acute effects of PGF2alpha on MMP-2 secretion from human ciliary muscle cells: a PKC- and ERK-dependent process. Invest Ophthalmol Vis Sci. 2005 May; 46(5):1706-13. PMID: 15851572.
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    34. Crosson CE, Yates PW, Bhat AN, Mukhin YV, Husain S. Evidence for multiple P2Y receptors in trabecular meshwork cells. J Pharmacol Exp Ther. 2004 May; 309(2):484-9. PMID: 14742747.
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    35. Sharif NA, Crider JY, Husain S, Kaddour-Djebbar I, Ansari HR, Abdel-Latif AA. Human ciliary muscle cell responses to FP-class prostaglandin analogs: phosphoinositide hydrolysis, intracellular Ca2+ mobilization and MAP kinase activation. J Ocul Pharmacol Ther. 2003 Oct; 19(5):437-55. PMID: 14583136.
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    36. Wingard CJ, Husain S, Williams J, James S. RhoA-Rho kinase mediates synergistic ET-1 and phenylephrine contraction of rat corpus cavernosum. . 2003 Nov; 285(5):R1145-52. PMID: 12893655.
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    37. Husain S, Jafri F. Prostaglandin F(2alpha) stimulates tyrosine phosphorylation of phospholipase C-gamma1. Biochem Biophys Res Commun. 2002 Oct 11; 297(5):1102-7. PMID: 12372399.
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    38. Husain S, Kaddour-Djebbar I, Abdel-Latif AA. Alterations in arachidonic acid release and phospholipase C-beta(1) expression in glaucomatous human ciliary muscle cells. Invest Ophthalmol Vis Sci. 2002 Apr; 43(4):1127-34. PMID: 11923256.
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