Richard A. Schmiedt

Title
InstitutionMedical University of South Carolina
DepartmentOtolaryngology - Head and Neck Surgery
AddressP.O. Box MSC 550
Phone843-792-7977
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Eckert MA, Harris KC, Lang H, Lewis MA, Schmiedt RA, Schulte BA, Steel KP, Vaden KI, Dubno JR. Translational and interdisciplinary insights into presbyacusis: A multidimensional disease. Hear Res. 2021 Mar 15; 402:108109. PMID: 33189490.
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    2. Dubno JR, Eckert MA, Lee FS, Matthews LJ, Schmiedt RA. Classifying human audiometric phenotypes of age-related hearing loss from animal models. J Assoc Res Otolaryngol. 2013 Oct; 14(5):687-701. PMID: 23740184.
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    3. Jyothi V, Li M, Kilpatrick LA, Smythe N, LaRue AC, Zhou D, Schulte BA, Schmiedt RA, Lang H. Unmyelinated auditory type I spiral ganglion neurons in congenic Ly5.1 mice. J Comp Neurol. 2010 Aug 15; 518(16):3254-71. PMID: 20575058.
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    4. Lang H, Jyothi V, Smythe NM, Dubno JR, Schulte BA, Schmiedt RA. Chronic reduction of endocochlear potential reduces auditory nerve activity: further confirmation of an animal model of metabolic presbyacusis. J Assoc Res Otolaryngol. 2010 Sep; 11(3):419-34. PMID: 20372958.
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    5. Lang H, Schulte BA, Goddard JC, Hedrick M, Schulte JB, Wei L, Schmiedt RA. Transplantation of mouse embryonic stem cells into the cochlea of an auditory-neuropathy animal model: effects of timing after injury. J Assoc Res Otolaryngol. 2008 Jun; 9(2):225-40. PMID: 18449604.
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    6. Moody MW, Lang H, Spiess AC, Smythe N, Lambert PR, Schmiedt RA. Topical application of mitomycin C to the middle ear is ototoxic in the gerbil. Otol Neurotol. 2006 Dec; 27(8):1186-92. PMID: 16788424.
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    7. Lang H, Ebihara Y, Schmiedt RA, Minamiguchi H, Zhou D, Smythe N, Liu L, Ogawa M, Schulte BA. Contribution of bone marrow hematopoietic stem cells to adult mouse inner ear: mesenchymal cells and fibrocytes. J Comp Neurol. 2006 May 10; 496(2):187-201. PMID: 16538683.
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    8. Lang H, Schulte BA, Zhou D, Smythe N, Spicer SS, Schmiedt RA. Nuclear factor kappaB deficiency is associated with auditory nerve degeneration and increased noise-induced hearing loss. J Neurosci. 2006 Mar 29; 26(13):3541-50. PMID: 16571762.
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    9. Lang H, Schulte BA, Schmiedt RA. Ouabain induces apoptotic cell death in type I spiral ganglion neurons, but not type II neurons. J Assoc Res Otolaryngol. 2005 Mar; 6(1):63-74. PMID: 15735933.
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    10. Wang Y, Meng A, Lang H, Brown SA, Konopa JL, Kindy MS, Schmiedt RA, Thompson JS, Zhou D. Activation of nuclear factor kappaB In vivo selectively protects the murine small intestine against ionizing radiation-induced damage. Cancer Res. 2004 Sep 01; 64(17):6240-6. PMID: 15342410.
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    11. Mills DM, Schmiedt RA. Metabolic presbycusis: differential changes in auditory brainstem and otoacoustic emission responses with chronic furosemide application in the gerbil. J Assoc Res Otolaryngol. 2004 Mar; 5(1):1-10. PMID: 14605922.
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    12. Lang H, Schulte BA, Schmiedt RA. Effects of chronic furosemide treatment and age on cell division in the adult gerbil inner ear. J Assoc Res Otolaryngol. 2003 Jun; 4(2):164-75. PMID: 12943371.
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    13. Schmiedt RA, Lang H, Okamura HO, Schulte BA. Effects of furosemide applied chronically to the round window: a model of metabolic presbyacusis. J Neurosci. 2002 Nov 01; 22(21):9643-50. PMID: 12417690.
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    14. Lang H, Schulte BA, Schmiedt RA. Endocochlear potentials and compound action potential recovery: functions in the C57BL/6J mouse. Hear Res. 2002 Oct; 172(1-2):118-26. PMID: 12361874.
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    15. Spector AA, Ameen M, Schmiedt RA. Modeling 3-D deformation of outer hair cells and their production of the active force in the cochlea. Biomech Model Mechanobiol. 2002 Oct; 1(2):123-35. PMID: 14595545.
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    16. Hamann I, Gleich O, Klump GM, Kittel MC, Boettcher FA, Schmiedt RA, Strutz J. Behavioral and evoked-potential thresholds in young and old Mongolian gerbils (Meriones unguiculatus). Hear Res. 2002 Sep; 171(1-2):82-95. PMID: 12204352.
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    17. Spiess AC, Lang H, Schulte BA, Spicer SS, Schmiedt RA. Effects of gap junction uncoupling in the gerbil cochlea. Laryngoscope. 2002 Sep; 112(9):1635-41. PMID: 12352678.
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    18. Schmiedt RA, Okamura HO, Lang H, Schulte BA. Ouabain application to the round window of the gerbil cochlea: a model of auditory neuropathy and apoptosis. J Assoc Res Otolaryngol. 2002 Sep; 3(3):223-33. PMID: 12382099.
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    19. Suryadevara AC, Schulte BA, Schmiedt RA, Slepecky NB. Auditory nerve fibers in young and quiet-aged gerbils: morphometric correlations with endocochlear potential. Hear Res. 2001 Nov; 161(1-2):45-53. PMID: 11744280.
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    20. Gratton MA, Smyth BJ, Lam CF, Boettcher FA, Schmiedt RA. Decline in the endocochlear potential corresponds to decreased Na,K-ATPase activity in the lateral wall of quiet-aged gerbils. Hear Res. 1997 Jun; 108(1-2):9-16. PMID: 9213117.
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    21. He N, Schmiedt RA. Fine structure of the 2 f1-f2 acoustic distortion products: effects of primary level and frequency ratios. J Acoust Soc Am. 1997 Jun; 101(6):3554-65. PMID: 9193044.
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    22. Schmiedt RA. Effects of aging on potassium homeostasis and the endocochlear potential in the gerbil cochlea. Hear Res. 1996 Dec 01; 102(1-2):125-32. PMID: 8951457.
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    23. Gratton MA, Schmiedt RA, Schulte BA. Age-related decreases in endocochlear potential are associated with vascular abnormalities in the stria vascularis. Hear Res. 1996 Dec 01; 102(1-2):181-90. PMID: 8951461.
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    24. Hellstrom LI, Schmiedt RA. Measures of tuning and suppression in single-fiber and whole-nerve responses in young and quiet-aged gerbils. J Acoust Soc Am. 1996 Nov; 100(5):3275-85. PMID: 8914310.
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    25. Schmiedt RA, Mills JH, Boettcher FA. Age-related loss of activity of auditory-nerve fibers. J Neurophysiol. 1996 Oct; 76(4):2799-803. PMID: 8899648.
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    26. Gratton MA, Schmiedt RA, Schulte BA. Age-related decreases in endocochlear potential are associated with vascular abnormalities in the stria vascularis. Hear Res. 1996 May; 94(1-2):116-24. PMID: 8789817.
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    27. He NJ, Schmiedt RA. Effects of aging on the fine structure of the 2f1-f2 acoustic distortion product. J Acoust Soc Am. 1996 Feb; 99(2):1002-15. PMID: 8609283.
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    28. Boettcher FA, Schmiedt RA. Distortion-product otoacoustic emissions in Mongolian gerbils with resistance to noise-induced hearing loss. J Acoust Soc Am. 1995 Dec; 98(6):3215-22. PMID: 8550946.
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    29. Boettcher FA, Mills JH, Dubno JR, Schmiedt RA. Masking of auditory brainstem responses in young and aged gerbils. Hear Res. 1995 Sep; 89(1-2):1-13. PMID: 8600113.
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    30. Boettcher FA, Gratton MA, Schmiedt RA. Effects of noise and age on the auditory system. Occup Med. 1995 Jul-Aug; 10(3):577-91. PMID: 8578420.
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    31. McGuirt JP, Schmiedt RA, Schulte BA. Development of cochlear potentials in the neonatal gerbil. Hear Res. 1995 Apr; 84(1-2):52-60. PMID: 7642455.
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    32. Sun XM, Schmiedt RA, He NJ, Lam CF. Modeling the fine structure of the 2f1-f2 acoustic distortion product. II. Model evaluation. J Acoust Soc Am. 1994 Oct; 96(4):2175-83. PMID: 7963031.
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    33. Sun XM, Schmiedt RA, He NJ, Lam CF. Modeling the fine structure of the 2f1-f2 acoustic distortion product. I. Model development. J Acoust Soc Am. 1994 Oct; 96(4):2166-74. PMID: 7963030.
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    34. Boettcher FA, Mills JH, Norton BL, Schmiedt RA. Age-related changes in auditory evoked potentials of gerbils. II. Response latencies. Hear Res. 1993 Dec; 71(1-2):146-56. PMID: 8113133.
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    35. He NJ, Schmiedt RA. Fine structure of the 2f1-f2 acoustic distortion product: changes with primary level. J Acoust Soc Am. 1993 Nov; 94(5):2659-69. PMID: 8270742.
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    36. Schulte BA, Schmiedt RA. Lateral wall Na,K-ATPase and endocochlear potentials decline with age in quiet-reared gerbils. Hear Res. 1992 Aug; 61(1-2):35-46. PMID: 1326507.
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    37. Tarnowski BI, Schmiedt RA, Hellstrom LI, Lee FS, Adams JC. Age-related changes in cochleas of mongolian gerbils. Hear Res. 1991 Jul; 54(1):123-34. PMID: 1917712.
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    38. Hellstrom LI, Schmiedt RA. Rate/level functions of auditory-nerve fibers in young and quiet-aged gerbils. Hear Res. 1991 Jun; 53(2):217-22. PMID: 1880076.
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    39. Hellstrom LI, Schmiedt RA. Compound action potential input/output functions in young and quiet-aged gerbils. Hear Res. 1990 Dec; 50(1-2):163-74. PMID: 2076969.
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    40. Mills JH, Schmiedt RA, Kulish LF. Age-related changes in auditory potentials of Mongolian gerbil. Hear Res. 1990 Jul; 46(3):201-10. PMID: 2394633.
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    41. Schmiedt RA, Mills JH, Adams JC. Tuning and suppression in auditory nerve fibers of aged gerbils raised in quiet or noise. Hear Res. 1990 May; 45(3):221-36. PMID: 2358415.
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    42. Schmiedt RA. Intermodulation distortion in the cochlea as shown by offset action potential (AP) masking curves. J Acoust Soc Am. 1990 Mar; 87(3):1357-9. PMID: 2324397.
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    43. Smith DI, Mills JH, Schmiedt RA. Frequency selectivity of the middle latency response. Hear Res. 1990 Jan; 43(2-3):95-105. PMID: 2312419.
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    44. Schmiedt RA. Spontaneous rates, thresholds and tuning of auditory-nerve fibers in the gerbil: comparisons to cat data. Hear Res. 1989 Oct; 42(1):23-35. PMID: 2584157.
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    45. Schmiedt RA. Acoustic distortion in the ear canal. I. Cubic difference tones: effects of acute noise injury. J Acoust Soc Am. 1986 May; 79(5):1481-90. PMID: 3711447.
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    46. Dolan TG, Mills JH, Schmiedt RA. Brainstem, whole-nerve AP and single-fiber suppression in the gerbil: normative data. Hear Res. 1985 Jun; 18(3):203-10. PMID: 4044422.
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    47. Dolan TG, Mills JH, Schmiedt RA. A comparison of brainstem, whole-nerve AP and single-fiber tuning curves in the gerbil: normative data. Hear Res. 1985 Mar; 17(3):259-66. PMID: 4019331.
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    48. Schmiedt RA. Acoustic injury and the physiology of hearing. J Acoust Soc Am. 1984 Nov; 76(5):1293-317. PMID: 6096430.
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    49. Schmiedt RA. Boundaries of two-tone rate suppression of cochlear-nerve activity. Hear Res. 1982 Aug; 7(3):335-51. PMID: 7118735.
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    50. Schmiedt RA. Effects of low-frequency biasing on auditory-nerve activity. J Acoust Soc Am. 1982 Jul; 72(1):142-50. PMID: 7108036.
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    51. Schmiedt RA, Adams JC. Stimulated acoustic emissions in the ear canal of the gerbil. Hear Res. 1981 Nov; 5(2-3):295-305. PMID: 7309644.
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    52. Schmiedt RA, Zwislocki JJ, Hamernik RP. Effects of hair cell lesions on responses of cochlear nerve fibers. I. Lesions, tuning curves, two-tone inhibition, and responses to trapezoidal-wave patterns. J Neurophysiol. 1980 May; 43(5):1367-89. PMID: 7373368.
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    53. Schmiedt RA, Zwislocki JJ. Effects of hair cell lesions on responses of cochlear nerve fibers. II. Single- and two-tone intensity functions in relation to tuning curves. J Neurophysiol. 1980 May; 43(5):1390-405. PMID: 7373369.
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    54. Schmiedt RA, Feng AS. Method for tracing single fibers in the organ of Corti with horseradish peroxidase. Hear Res. 1980 Jan; 2(1):79-85. PMID: 7351393.
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    55. Schmiedt RA, Zwislocki JJ. Low-frequency neural and cochlear-microphonic tuning curves in the gerbil. J Acoust Soc Am. 1978 Aug; 64(2):502-7. PMID: 712012.
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    56. Schmiedt RA, Zwislocki JJ. Comparison of sound-transmission and cochlear-microphonic characteristics in Mongolian gerbil and guinea pig. J Acoust Soc Am. 1977 Jan; 61(1):133-49. PMID: 833365.
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    57. Sokolich WG, Hamernik RP, Zwislocki JJ, Schmiedt RA. Inferred response polarities of cochlear hair cells. J Acoust Soc Am. 1976 Apr; 59(4):963-74. PMID: 1262595.
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