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Patrick K. Randall

Title
InstitutionMedical University of South Carolina
DepartmentPsychiatry and Behavioral Sciences
AddressP.O. Box MSC 861
444N
67 President St.
Phone843-792-5235
Fax843-792-7353
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    Collapse Overview 
    Collapse overview
    Dr. Randall's research focuses primarily on central nervous system effects of ethanol ranging from animal studies to clinical trials for alcoholism treatment. He is particularly active in the application of novel statistical methods (e.g. hierarchical linear modeling, partial least squares) to both drinking data and fMRI imaging.

    Collapse keywords
    alcohol dependence, pharmalogical treatment, hierarchical linear models, partial least squares, fMRI

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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Anton RF, Latham PK, Voronin KE, Randall PK, Book SW, Hoffman M, Schacht JP. Nicotine-Use/Smoking Is Associated with the Efficacy of Naltrexone in the Treatment of Alcohol Dependence. Alcohol Clin Exp Res. 2018 Apr; 42(4):751-760. PMID: 29431852.
      View in: PubMed
    2. Schacht JP, Voronin KE, Randall PK, Anton RF. Dopaminergic Genetic Variation Influences Aripiprazole Effects on Alcohol Self-Administration and the Neural Response to Alcohol Cues in a Randomized Trial. Neuropsychopharmacology. 2018 05; 43(6):1247-1256. PMID: 29362512.
      View in: PubMed
    3. Schacht JP, Randall PK, Latham PK, Voronin KE, Book SW, Myrick H, Anton RF. Predictors of Naltrexone Response in a Randomized Trial: Reward-Related Brain Activation, OPRM1 Genotype, and Smoking Status. Neuropsychopharmacology. 2017 12; 42(13):2654. PMID: 29123234.
      View in: PubMed
    4. Anton RF, Schacht JP, Voronin KE, Randall PK. Aripiprazole Suppression of Drinking in a Clinical Laboratory Paradigm: Influence of Impulsivity and Self-Control. Alcohol Clin Exp Res. 2017 Jul; 41(7):1370-1380. PMID: 28493623.
      View in: PubMed
    5. Schacht JP, Randall PK, Latham PK, Voronin KE, Book SW, Myrick H, Anton RF. Predictors of Naltrexone Response in a Randomized Trial: Reward-Related Brain Activation, OPRM1 Genotype, and Smoking Status. Neuropsychopharmacology. 2017 Dec; 42(13):2640-2653. PMID: 28409564.
      View in: PubMed
    6. Nimitvilai S, Uys JD, Woodward JJ, Randall PK, Ball LE, Williams RW, Jones BC, Lu L, Grant KA, Mulholland PJ. Orbitofrontal Neuroadaptations and Cross-Species Synaptic Biomarkers in Heavy-Drinking Macaques. J Neurosci. 2017 03 29; 37(13):3646-3660. PMID: 28270566.
      View in: PubMed
    7. Rinker JA, Fulmer DB, Trantham-Davidson H, Smith ML, Williams RW, Lopez MF, Randall PK, Chandler LJ, Miles MF, Becker HC, Mulholland PJ. Differential potassium channel gene regulation in BXD mice reveals novel targets for pharmacogenetic therapies to reduce heavy alcohol drinking. Alcohol. 2017 Feb; 58:33-45. PMID: 27432260.
      View in: PubMed
    8. Adams ZW, Schacht JP, Randall P, Anton RF. The Reasons for Heavy Drinking Questionnaire: Factor Structure and Validity in Alcohol-Dependent Adults Involved in Clinical Trials. J Stud Alcohol Drugs. 2016 Mar; 77(2):354-61. PMID: 26997195.
      View in: PubMed
    9. Beckley JT, Randall PK, Smith RJ, Hughes BA, Kalivas PW, Woodward JJ. Phenotype-dependent inhibition of glutamatergic transmission on nucleus accumbens medium spiny neurons by the abused inhalant toluene. Addict Biol. 2016 May; 21(3):530-46. PMID: 25752326.
      View in: PubMed
    10. Padula AE, Griffin WC, Lopez MF, Nimitvilai S, Cannady R, McGuier NS, Chesler EJ, Miles MF, Williams RW, Randall PK, Woodward JJ, Becker HC, Mulholland PJ. KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction. Neuropsychopharmacology. 2015 Jul; 40(8):1928-39. PMID: 25662840.
      View in: PubMed
    11. Miller PM, Book SW, Thomas S, Smith JP, Randall PK, Randall CL. The potential utility of drinking motive questions to screen at-risk drinking in socially anxious patients. J Subst Use. 2014 Jun 01; 19(3):225-228. PMID: 24982593.
      View in: PubMed
    12. Gass JT, Glen WB, McGonigal JT, Trantham-Davidson H, Lopez MF, Randall PK, Yaxley R, Floresco SB, Chandler LJ. Adolescent alcohol exposure reduces behavioral flexibility, promotes disinhibition, and increases resistance to extinction of ethanol self-administration in adulthood. Neuropsychopharmacology. 2014 Oct; 39(11):2570-83. PMID: 24820536.
      View in: PubMed
    13. Schacht JP, Anton RF, Randall PK, Li X, Henderson S, Myrick H. Varenicline effects on drinking, craving and neural reward processing among non-treatment-seeking alcohol-dependent individuals. Psychopharmacology (Berl). 2014 Sep; 231(18):3799-807. PMID: 24647921.
      View in: PubMed
    14. LaRowe SD, Kalivas PW, Nicholas JS, Randall PK, Mardikian PN, Malcolm RJ. A double-blind placebo-controlled trial of N-acetylcysteine in the treatment of cocaine dependence. Am J Addict. 2013 Sep-Oct; 22(5):443-52. PMID: 23952889.
      View in: PubMed
    15. DeSantis SM, Bandyopadhyay D, Baker NL, Randall PK, Anton RF, Prisciandaro JJ. Modeling longitudinal drinking data in clinical trials: an application to the COMBINE study. Drug Alcohol Depend. 2013 Sep 01; 132(1-2):244-50. PMID: 23566774.
      View in: PubMed
    16. Book SW, Thomas SE, Smith JP, Randall PK, Kushner MG, Bernstein GA, Specker SM, Miller PM, Randall CL. Treating individuals with social anxiety disorder and at-risk drinking: phasing in a brief alcohol intervention following paroxetine. J Anxiety Disord. 2013 Mar; 27(2):252-8. PMID: 23523988.
      View in: PubMed
    17. Schacht JP, Anton RF, Randall PK, Li X, Henderson S, Myrick H. Effects of a GABA-ergic medication combination and initial alcohol withdrawal severity on cue-elicited brain activation among treatment-seeking alcoholics. Psychopharmacology (Berl). 2013 Jun; 227(4):627-37. PMID: 23389755.
      View in: PubMed
    18. Schacht JP, Anton RF, Voronin KE, Randall PK, Li X, Henderson S, Myrick H. Interacting effects of naltrexone and OPRM1 and DAT1 variation on the neural response to alcohol cues. Neuropsychopharmacology. 2013 Feb; 38(3):414-22. PMID: 23032071.
      View in: PubMed
    19. Stewart SH, Koch DG, Willner IR, Randall PK, Reuben A. Hair ethyl glucuronide is highly sensitive and specific for detecting moderate-to-heavy drinking in patients with liver disease. Alcohol Alcohol. 2013 Jan-Feb; 48(1):83-7. PMID: 23015609.
      View in: PubMed
    20. Griffin WC, McGovern RW, Bell GH, Randall PK, Middaugh LD, Patrick KS. Interactive effects of methylphenidate and alcohol on discrimination, conditioned place preference and motor coordination in C57BL/6J mice. Psychopharmacology (Berl). 2013 Feb; 225(3):613-25. PMID: 22955568.
      View in: PubMed
    21. Anton RF, Voronin KK, Randall PK, Myrick H, Tiffany A. Naltrexone modification of drinking effects in a subacute treatment and bar-lab paradigm: influence of OPRM1 and dopamine transporter (SLC6A3) genes. Alcohol Clin Exp Res. 2012 Nov; 36(11):2000-7. PMID: 22551036.
      View in: PubMed
    22. Badanich KA, Doremus-Fitzwater TL, Mulholland PJ, Randall PK, Delpire E, Becker HC. NR2B-deficient mice are more sensitive to the locomotor stimulant and depressant effects of ethanol. Genes Brain Behav. 2011 Oct; 10(7):805-816. PMID: 21762461.
      View in: PubMed
    23. Schacht JP, Randall PK, Waid LR, Baros AM, Latham PK, Wright TM, Myrick H, Anton RF. Neurocognitive performance, alcohol withdrawal, and effects of a combination of flumazenil and gabapentin in alcohol dependence. Alcohol Clin Exp Res. 2011 Nov; 35(11):2030-8. PMID: 21631542.
      View in: PubMed
    24. Anton RF, Myrick H, Wright TM, Latham PK, Baros AM, Waid LR, Randall PK. Gabapentin combined with naltrexone for the treatment of alcohol dependence. Am J Psychiatry. 2011 Jul; 168(7):709-17. PMID: 21454917.
      View in: PubMed
    25. Schacht JP, Anton RF, Randall PK, Li X, Henderson S, Myrick H. Stability of fMRI striatal response to alcohol cues: a hierarchical linear modeling approach. Neuroimage. 2011 May 01; 56(1):61-8. PMID: 21316465.
      View in: PubMed
    26. Thomas SE, Bacon AK, Randall PK, Brady KT, See RE. An acute psychosocial stressor increases drinking in non-treatment-seeking alcoholics. Psychopharmacology (Berl). 2011 Nov; 218(1):19-28. PMID: 21274703.
      View in: PubMed
    27. Thomas SE, Randall PK, Brady K, See RE, Drobes DJ. An acute psychosocial stressor does not potentiate alcohol cue reactivity in non-treatment-seeking alcoholics. Alcohol Clin Exp Res. 2011 Mar; 35(3):464-73. PMID: 21143244.
      View in: PubMed
    28. Granholm AC, Zaman V, Godbee J, Smith M, Ramadan R, Umphlet C, Randall P, Bhat NR, Rohrer B, Middaugh LD, Boger HA. Prenatal LPS increases inflammation in the substantia nigra of Gdnf heterozygous mice. Brain Pathol. 2011 May; 21(3):330-48. PMID: 20969653.
      View in: PubMed
    29. Boger HA, Mannangatti P, Samuvel DJ, Saylor AJ, Bender TS, McGinty JF, Fortress AM, Zaman V, Huang P, Middaugh LD, Randall PK, Jayanthi LD, Rohrer B, Helke KL, Granholm AC, Ramamoorthy S. Effects of brain-derived neurotrophic factor on dopaminergic function and motor behavior during aging. Genes Brain Behav. 2011 Mar; 10(2):186-98. PMID: 20860702.
      View in: PubMed
    30. Myrick H, Li X, Randall PK, Henderson S, Voronin K, Anton RF. The effect of aripiprazole on cue-induced brain activation and drinking parameters in alcoholics. J Clin Psychopharmacol. 2010 Aug; 30(4):365-72. PMID: 20571434.
      View in: PubMed
    31. Greenfield SF, Pettinati HM, O'Malley S, Randall PK, Randall CL. Gender differences in alcohol treatment: an analysis of outcome from the COMBINE study. Alcohol Clin Exp Res. 2010 Oct; 34(10):1803-12. PMID: 20645934.
      View in: PubMed
    32. Tonigan JS, Book SW, Pagano ME, Randall PK, Smith JP, Randall CL. 12-Step Therapy and Women with and without Social Phobia: A Study of the Effectiveness of 12-Step Therapy to Facilitate AA Engagement. Alcohol Treat Q. 2010 Apr 01; 28(2):151-162. PMID: 21423569.
      View in: PubMed
    33. Stewart SH, Law TL, Randall PK, Newman R. Phosphatidylethanol and alcohol consumption in reproductive age women. Alcohol Clin Exp Res. 2010 Mar 01; 34(3):488-92. PMID: 20028353.
      View in: PubMed
    34. Anton RF, Myrick H, Baros AM, Latham PK, Randall PK, Wright TM, Stewart SH, Waid R, Malcolm R. Efficacy of a combination of flumazenil and gabapentin in the treatment of alcohol dependence: relationship to alcohol withdrawal symptoms. J Clin Psychopharmacol. 2009 Aug; 29(4):334-42. PMID: 19593171.
      View in: PubMed
    35. Stewart SH, Reuben A, Brzezinski WA, Koch DG, Basile J, Randall PK, Miller PM. Preliminary evaluation of phosphatidylethanol and alcohol consumption in patients with liver disease and hypertension. Alcohol Alcohol. 2009 Sep-Oct; 44(5):464-7. PMID: 19535495.
      View in: PubMed
    36. Myrick H, Malcolm R, Randall PK, Boyle E, Anton RF, Becker HC, Randall CL. A double-blind trial of gabapentin versus lorazepam in the treatment of alcohol withdrawal. Alcohol Clin Exp Res. 2009 Sep; 33(9):1582-8. PMID: 19485969.
      View in: PubMed
    37. Book SW, Thomas SE, Dempsey JP, Randall PK, Randall CL. Social anxiety impacts willingness to participate in addiction treatment. Addict Behav. 2009 May; 34(5):474-6. PMID: 19195794.
      View in: PubMed
    38. Stewart SH, Oroszi G, Randall PK, Anton RF. COMT genotype influences the effect of alcohol on blood pressure: results from the COMBINE study. Am J Hypertens. 2009 Jan; 22(1):87-91. PMID: 19023276.
      View in: PubMed
    39. Stewart SH, Latham PK, Miller PM, Randall P, Anton RF. Blood pressure reduction during treatment for alcohol dependence: results from the Combining Medications and Behavioral Interventions for Alcoholism (COMBINE) study. Addiction. 2008 Oct; 103(10):1622-8. PMID: 18821872.
      View in: PubMed
    40. Voronin K, Randall P, Myrick H, Anton R. Aripiprazole effects on alcohol consumption and subjective reports in a clinical laboratory paradigm--possible influence of self-control. Alcohol Clin Exp Res. 2008 Nov; 32(11):1954-61. PMID: 18782344.
      View in: PubMed
    41. Dempsey JP, Randall PK, Thomas SE, Book SW, Carrigan MH. Treatment of social anxiety with paroxetine: mediation of changes in anxiety and depression symptoms. Compr Psychiatry. 2009 Mar-Apr; 50(2):135-41. PMID: 19216890.
      View in: PubMed
    42. Nguyen SA, Suranyi P, Ravenel JG, Randall PK, Romano PB, Strom KA, Costello P, Schoepf UJ. Iso-osmolality versus low-osmolality iodinated contrast medium at intravenous contrast-enhanced CT: effect on kidney function. Radiology. 2008 Jul; 248(1):97-105. PMID: 18483232.
      View in: PubMed
    43. Myrick H, Anton RF, Li X, Henderson S, Randall PK, Voronin K. Effect of naltrexone and ondansetron on alcohol cue-induced activation of the ventral striatum in alcohol-dependent people. Arch Gen Psychiatry. 2008 Apr; 65(4):466-75. PMID: 18391135.
      View in: PubMed
    44. Thomas SE, Miller PM, Randall PK, Book SW. Improving acceptance of naltrexone in community addiction treatment centers: a pilot study. J Subst Abuse Treat. 2008 Oct; 35(3):260-8. PMID: 18329227.
      View in: PubMed
    45. Thomas SE, Randall PK, Book SW, Randall CL. A complex relationship between co-occurring social anxiety and alcohol use disorders: what effect does treating social anxiety have on drinking? Alcohol Clin Exp Res. 2008 Jan; 32(1):77-84. PMID: 18028529.
      View in: PubMed
    46. Dempsey JP, Cohen LM, Hobson VL, Randall PK. Appetitive nature of drug cues re-confirmed with physiological measures and the potential role of stage of change. Psychopharmacology (Berl). 2007 Oct; 194(2):253-60. PMID: 17588224.
      View in: PubMed
    47. Griffin WC, Randall PK, Middaugh LD. Intravenous cocaine self-administration: individual differences in male and female C57BL/6J mice. Pharmacol Biochem Behav. 2007 Jun-Jul; 87(2):267-79. PMID: 17561241.
      View in: PubMed
    48. Book SW, Thomas SE, Randall PK, Randall CL. Paroxetine reduces social anxiety in individuals with a co-occurring alcohol use disorder. J Anxiety Disord. 2008; 22(2):310-8. PMID: 17448631.
      View in: PubMed
    49. Wright TM, Myrick H, Malcolm R, Randall P, Boyle E, Henderson S, Anton R. Impact of lifetime alcohol quit attempts and medicated detoxifications on time to relapse during an index alcohol detoxification. J Addict Med. 2007 Mar; 1(1):15-20. PMID: 21768927.
      View in: PubMed
    50. Malcolm R, Myrick LH, Veatch LM, Boyle E, Randall PK. Self-reported sleep, sleepiness, and repeated alcohol withdrawals: a randomized, double blind, controlled comparison of lorazepam vs gabapentin. J Clin Sleep Med. 2007 Feb 15; 3(1):24-32. PMID: 17557449.
      View in: PubMed
    51. Brady KT, Waldrop AE, McRae AL, Back SE, Saladin ME, Upadhyaya HP, Anton RF, Randall PK. The impact of alcohol dependence and posttraumatic stress disorder on cold pressor task response. J Stud Alcohol. 2006 Sep; 67(5):700-6. PMID: 16847538.
      View in: PubMed
    52. Brady KT, Back SE, Waldrop AE, McRae AL, Anton RF, Upadhyaya HP, Saladin ME, Randall PK. Cold pressor task reactivity: predictors of alcohol use among alcohol-dependent individuals with and without comorbid posttraumatic stress disorder. Alcohol Clin Exp Res. 2006 Jun; 30(6):938-46. PMID: 16737451.
      View in: PubMed
    53. Liu J, Lewohl JM, Harris RA, Iyer VR, Dodd PR, Randall PK, Mayfield RD. Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. Neuropsychopharmacology. 2006 Jul; 31(7):1574-82. PMID: 16292326.
      View in: PubMed
    54. Rellini AH, McCall KM, Randall PK, Meston CM. The relationship between women's subjective and physiological sexual arousal. Psychophysiology. 2005 Jan; 42(1):116-24. PMID: 15720587.
      View in: PubMed
    55. Liu J, Lewohl JM, Dodd PR, Randall PK, Harris RA, Mayfield RD. Gene expression profiling of individual cases reveals consistent transcriptional changes in alcoholic human brain. J Neurochem. 2004 Sep; 90(5):1050-8. PMID: 15312160.
      View in: PubMed
    56. Holahan CJ, Moos RH, Holahan CK, Cronkite RC, Randall PK. Unipolar depression, life context vulnerabilities, and drinking to cope. J Consult Clin Psychol. 2004 Apr; 72(2):269-75. PMID: 15065960.
      View in: PubMed
    57. Shaw H, Ramirez L, Trost A, Randall P, Stice E. Body image and eating disturbances across ethnic groups: more similarities than differences. Psychol Addict Behav. 2004 Mar; 18(1):12-8. PMID: 15008681.
      View in: PubMed
    58. Stice E, Ragan J, Randall P. Prospective relations between social support and depression: differential direction of effects for parent and peer support? J Abnorm Psychol. 2004 Feb; 113(1):155-9. PMID: 14992668.
      View in: PubMed
    59. Mayfield RD, Liu J, Randall PK, Lewohl JM, Dodd PR, Harris RA. Methods for the identification of differentially expressed genes in human post-mortem brain. Methods. 2003 Dec; 31(4):301-5. PMID: 14597314.
      View in: PubMed
    60. Honse Y, Randall PK, Leslie SW. Prenatal ethanol exposure modifies [3H]MK-801 binding to NMDA receptors: spermidine and ifenprodil. Alcohol Clin Exp Res. 2003 Dec; 27(12):1993-2001. PMID: 14691388.
      View in: PubMed
    61. Ferrani-Kile K, Randall PK, Leslie SW. Acute ethanol affects phosphorylation state of the NMDA receptor complex: implication of tyrosine phosphatases and protein kinase A. Brain Res Mol Brain Res. 2003 Jul 04; 115(1):78-86. PMID: 12824058.
      View in: PubMed
    62. Holahan CJ, Moos RH, Holahan CK, Cronkite RC, Randall PK. Drinking to cope and alcohol use and abuse in unipolar depression: a 10-year model. J Abnorm Psychol. 2003 Feb; 112(1):159-65. PMID: 12653424.
      View in: PubMed
    63. Smits JA, Telch MJ, Randall PK. An examination of the decline in fear and disgust during exposure-based treatment. Behav Res Ther. 2002 Nov; 40(11):1243-53. PMID: 12384321.
      View in: PubMed
    64. Jaworski JN, Gonzales RA, Randall PK. Effect of dopamine D2/D3 receptor antagonist sulpiride on amphetamine-induced changes in striatal extracellular dopamine. Eur J Pharmacol. 2001 Apr 27; 418(3):201-6. PMID: 11343690.
      View in: PubMed
    65. Holahan CJ, Moos RH, Holahan CK, Cronkite RC, Randall PK. Drinking to cope, emotional distress and alcohol use and abuse: a ten-year model. J Stud Alcohol. 2001 Mar; 62(2):190-8. PMID: 11327185.
      View in: PubMed
    66. Avalos M, Mak C, Randall PK, Trzeciakowski JP, Abell C, Kwan SW, Wilcox RE. Nonlinear analysis of partial dopamine agonist effects on cAMP in C6 glioma cells. J Pharmacol Toxicol Methods. 2001 Jan-Feb; 45(1):17-37. PMID: 11489662.
      View in: PubMed
    67. Yim HJ, Robinson DL, White ML, Jaworski JN, Randall PK, Lancaster FE, Gonzales RA. Dissociation between the time course of ethanol and extracellular dopamine concentrations in the nucleus accumbens after a single intraperitoneal injection. Alcohol Clin Exp Res. 2000 Jun; 24(6):781-8. PMID: 10888065.
      View in: PubMed
    68. Hughes PD, Kim YN, Randall PK, Leslie SW. Effect of prenatal ethanol exposure on the developmental profile of the NMDA receptor subunits in rat forebrain and hippocampus. Alcohol Clin Exp Res. 1998 Sep; 22(6):1255-61. PMID: 9756040.
      View in: PubMed
    69. Yim HJ, Schallert T, Randall PK, Gonzales RA. Comparison of local and systemic ethanol effects on extracellular dopamine concentration in rat nucleus accumbens by microdialysis. Alcohol Clin Exp Res. 1998 Apr; 22(2):367-74. PMID: 9581642.
      View in: PubMed
    70. Ripley TL, Jaworski J, Randall PK, Gonzales RA. Repeated perfusion with elevated potassium in in vivo microdialysis--A method for detecting small changes in extracellular dopamine. J Neurosci Methods. 1997 Dec 30; 78(1-2):7-14. PMID: 9496997.
      View in: PubMed
    71. Robichon R, Randall PK, Leslie SW. A partial agonist model used in the allosteric modulation of the NMDA receptor. Eur J Pharmacol. 1997 Jun 11; 328(2-3):255-63. PMID: 9218709.
      View in: PubMed
    72. Yim HJ, Schallert T, Randall PK, Bungay PM, Gonzales RA. Effect of ethanol on extracellular dopamine in rat striatum by direct perfusion with microdialysis. J Neurochem. 1997 Apr; 68(4):1527-33. PMID: 9084423.
      View in: PubMed
    73. Bremner JD, Randall P, Vermetten E, Staib L, Bronen RA, Mazure C, Capelli S, McCarthy G, Innis RB, Charney DS. Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse--a preliminary report. Biol Psychiatry. 1997 Jan 01; 41(1):23-32. PMID: 8988792.
      View in: PubMed
    74. Lee YH, Spuhler-Phillips K, Randall PK, Leslle SW. Effects of prenatal ethanol exposure on voltage-dependent calcium entry into neonatal whole brain-dissociated neurons. Alcohol Clin Exp Res. 1996 Aug; 20(5):921-8. PMID: 8865969.
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    75. Mak CK, Avalos M, Randall PK, Kwan SW, Abell CW, Neumeyer JL, Whisennand R, Wilcox RE. Improved models for pharmacological null experiments: calculation of drug efficacy at recombinant D1A dopamine receptors stably expressed in clonal cell lines. Neuropharmacology. 1996 May; 35(5):549-70. PMID: 8887963.
      View in: PubMed
    76. Young KA, Randall PK, Wilcox RE. Startle and sensorimotor correlates of ventral thalamic dopamine and GABA in rodents. Neuroreport. 1995 Dec 15; 6(18):2495-9. PMID: 8741749.
      View in: PubMed
    77. Randall PK, Bremner JD, Krystal JH, Nagy LM, Heninger GR, Nicolaou AL, Charney DS. Effects of the benzodiazepine antagonist flumazenil in PTSD. Biol Psychiatry. 1995 Sep 01; 38(5):319-24. PMID: 7495926.
      View in: PubMed
    78. Bremner JD, Randall P, Scott TM, Bronen RA, Seibyl JP, Southwick SM, Delaney RC, McCarthy G, Charney DS, Innis RB. MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. Am J Psychiatry. 1995 Jul; 152(7):973-81. PMID: 7793467.
      View in: PubMed
    79. Milton GV, Randall PK, Erickson CK. Low-dose effect of ethanol on locomotor activity induced by activation of the mesolimbic system. Alcohol Clin Exp Res. 1995 Jun; 19(3):768-76. PMID: 7573807.
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    80. Spuhler-Phillips K, Gonzalez J, Randall PK, Leslie SW. Alteration of [3H]MK-801 binding associated with the N-methyl-D-Aspartate receptor complex by acute ethanol in rat cortex and hippocampus in vitro. Alcohol Clin Exp Res. 1995 Apr; 19(2):305-13. PMID: 7625562.
      View in: PubMed
    81. Abi-Dargham A, Gandelman M, Zoghbi SS, Laruelle M, Baldwin RM, Randall P, Zea-Ponce Y, Charney DS, Hoffer PB, Innis RB. Reproducibility of SPECT measurement of benzodiazepine receptors in human brain with iodine-123-iomazenil. J Nucl Med. 1995 Feb; 36(2):167-75. PMID: 7830108.
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    82. Lee YH, Spuhler-Phillips K, Randall PK, Leslie SW. Effects of prenatal ethanol exposure on N-methyl-D-aspartate-mediated calcium entry into dissociated neurons. J Pharmacol Exp Ther. 1994 Dec; 271(3):1291-8. PMID: 7996437.
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    83. Young KA, Hicks PB, Randall PK, Wilcox RE. Behavioral and frontal cortical metabolic effects of apomorphine and muscimol microinjections into the mediodorsal thalamic nucleus. J Neural Transm Gen Sect. 1994; 98(2):119-32. PMID: 7734109.
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    84. Mandel RJ, Hartgraves SL, Severson JA, Woodward JJ, Wilcox RE, Randall PK. A quantitative estimate of the role of striatal D-2 receptor proliferation in dopaminergic behavioral supersensitivity: the contribution of mesolimbic dopamine to the magnitude of 6-OHDA lesion-induced agonist sensitivity in the rat. Behav Brain Res. 1993 Dec 31; 59(1-2):53-64. PMID: 8155293.
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    85. Mayfield RD, Randall PK, Spirduso WW, Wilcox RE. Apomorphine and amphetamine produce differential effects on the speed and success of reaction time responding in the rat. Pharmacol Biochem Behav. 1993 Dec; 46(4):769-75. PMID: 8309953.
      View in: PubMed
    86. Mayfield RD, Randall PK, Spirduso WW, Wilcox RE. Selective D1 and D2 dopamine receptor antagonists produce differential effects on reaction time in the rat. Pharmacol Biochem Behav. 1993 Dec; 46(4):759-68. PMID: 8309952.
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    87. Weaver MS, Lee YH, Morris JL, Randall PK, Schallert T, Leslie SW. Effects of in vitro ethanol and fetal ethanol exposure on glutathione stimulation of N-methyl-D-aspartate receptor function. Alcohol Clin Exp Res. 1993 Jun; 17(3):643-50. PMID: 8333595.
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    88. Brown LM, Sims JS, Randall P, Wilcox R, Leslie SW. Omega-conotoxin increases sleep time following ethanol injection. Alcohol. 1993 Mar-Apr; 10(2):159-62. PMID: 8442894.
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    89. Leslie SW, Brown LM, Trent RD, Lee YH, Morris JL, Jones TW, Randall PK, Lau SS, Monks TJ. Stimulation of N-methyl-D-aspartate receptor-mediated calcium entry into dissociated neurons by reduced and oxidized glutathione. Mol Pharmacol. 1992 Feb; 41(2):308-14. PMID: 1347146.
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    90. Mandel RJ, Wilcox RE, Randall PK. Behavioral quantification of striatal dopaminergic supersensitivity after bilateral 6-hydroxydopamine lesions in the mouse. Pharmacol Biochem Behav. 1992 Feb; 41(2):343-7. PMID: 1574523.
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    91. Yurek DM, Randall PK. Striatal depth EEG reveals postsynaptic activity of striatal neurons following dopamine receptor stimulation and blockade. J Neurosci Methods. 1991 Mar; 37(1):81-91. PMID: 2072738.
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    92. Young KA, Randall PK, Wilcox RE. Dose and time response analysis of apomorphine's effect on prepulse inhibition of acoustic startle. Behav Brain Res. 1991 Jan 31; 42(1):43-8. PMID: 2029343.
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    93. Wilcox RE, Severson JA, Woodward JJ, Randall PK, Vaughn DM, Riffee WH. Behavioral sensitization following a single apomorphine pretreatment--selective effects on the dopamine release process. Brain Res. 1990 Sep 24; 528(1):109-13. PMID: 2147118.
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    94. Vaughn DM, Severson JA, Woodward JJ, Randall PK, Riffee WH, Leslie SW, Wilcox RE. Behavioral sensitization following subchronic apomorphine treatment--possible neurochemical basis. Brain Res. 1990 Aug 27; 526(1):37-44. PMID: 2150341.
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    95. Mandel RJ, Yurek DM, Randall PK. Behavioral demonstration of a reciprocal interaction between dopamine receptor subtypes in the mouse striatum: possible involvement of the striato-nigral pathway. Brain Res Bull. 1990 Aug; 25(2):285-92. PMID: 2146002.
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    96. Severson JA, Randall PK, Wilcox RE. Single apomorphine pretreatment results in a rapid decline in high-affinity dopamine binding to the striatal dopamine D-2 receptor. Eur J Pharmacol. 1990 Apr 25; 188(4-5):283-6. PMID: 2114303.
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    97. Mandel RJ, Randall PK. Bromocriptine-induced rotation: characterization using a striatal efferent lesion in the mouse. Brain Res Bull. 1990 Feb; 24(2):175-80. PMID: 2108786.
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    98. Randall PK. Quantitative analysis of behavioral pharmacological data. Ann N Y Acad Sci. 1988; 515:124-41. PMID: 3364882.
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    99. Flurkey K, Randall PK, Sinha YN, Ermini M, Finch CE. Transient shortening of estrous cycles in aging C57BL/6J mice: effects of spontaneous pseudopregnancy, progesterone, L-dihydroxyphenylalanine, and hydergine. Biol Reprod. 1987 May; 36(4):949-59. PMID: 3593860.
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    100. Morgan DG, Randall JS, Telford NA, Gordon MN, Sinha YN, Finch CE, Randall PK. Genotypic influences on pituitary responsiveness to haloperidol in mice. Psychoneuroendocrinology. 1987; 12(3):211-8. PMID: 3615750.
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    101. May PC, Osterburg HH, Mandel RJ, Morgan DG, Randall PK, Finch CE. Alteration of calmodulin distribution does not accompany dopaminergic supersensitization of the mouse striatum. J Neurosci Res. 1987; 17(3):247-50. PMID: 3037094.
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    102. Randall PK, Randall JS. Mouse strain differences in apomorphine-induced behavior: an empirical and methodological study. Behav Neurosci. 1986 Feb; 100(1):85-92. PMID: 3954884.
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    103. Hartgraves SL, Randall PK. Dopamine agonist-induced stereotypic grooming and self-mutilation following striatal dopamine depletion. Psychopharmacology (Berl). 1986; 90(3):358-63. PMID: 3097724.
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    104. Yurek DM, Randall PK. Simultaneous catalepsy and apomorphine-induced stereotypic behavior in mice. Life Sci. 1985 Nov 04; 37(18):1665-73. PMID: 4058245.
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    105. Randall PK. Quantification of dopaminergic supersensitization using apomorphine-induced behavior in the mouse. Life Sci. 1985 Oct 14; 37(15):1419-23. PMID: 4046742.
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    106. Severson JA, Randall PK. D-2 dopamine receptors in aging mouse striatum: determination of high- and low-affinity agonist binding sites. J Pharmacol Exp Ther. 1985 May; 233(2):361-8. PMID: 3158731.
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    107. Randall PK, Severson JA, Hurd SM, McClure WO. Effect of duration of haloperidol treatment on DA receptor supersensitization in aging C57BL/6J mice. Brain Res. 1985 Apr 29; 333(1):85-95. PMID: 4039618.
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    108. Mandel RJ, Randall PK. Quantification of lesion-induced dopaminergic supersensitivity using the rotational model in the mouse. Brain Res. 1985 Mar 25; 330(2):358-63. PMID: 3921193.
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    109. Randall PK. Lesion-induced DA supersensitivity in aging C57BL/6J mice. Brain Res. 1984 Aug 13; 308(2):333-6. PMID: 6434153.
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    110. Ahlskog JE, Randall PK, Hernandez L, Hoebel BG. Diminished amphetamine anorexia and enhanced fenfluramine anorexia after midbrain 6-hydroxydopamine. Psychopharmacology (Berl). 1984; 82(1-2):118-21. PMID: 6420820.
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    111. Severson JA, Randall PK. Localization of [3H]N-propylnorapomorphine binding in mouse striatum. Brain Res. 1983 Nov 21; 279(1-2):295-8. PMID: 6416612.
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    112. Nelson JF, Felicio LS, Randall PK, Sims C, Finch CE. A longitudinal study of estrous cyclicity in aging C57BL/6J mice: I. Cycle frequency, length and vaginal cytology. Biol Reprod. 1982 Sep; 27(2):327-39. PMID: 6889895.
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    113. Randall PK, Severson JA, Finch CE. Aging and the regulation of striatal dopaminergic mechanisms in mice. J Pharmacol Exp Ther. 1981 Dec; 219(3):695-700. PMID: 7197719.
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    114. Severson JA, Randall PK, Finch CE. Genotypic influences on striatal dopaminergic regulation in mice. Brain Res. 1981 Apr 06; 210(1-2):201-15. PMID: 6261873.
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    115. Baez LA, Ahlskog JE, Randall PK. Body weight and regulatory deficits following unilateral nigrostriatal lesions. Brain Res. 1977 Sep 02; 132(3):467-76. PMID: 912400.
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    116. Campbell BA, Randall PK. The effect of reinstatement stimulus conditions on the maintenance of long-term memory. Dev Psychobiol. 1976 Jul; 9(4):325-33. PMID: 955291.
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    117. Randall PK, Campbell BA. Ontogeny of behavioral arousal in rats: effect of maternal and sibling presence. J Comp Physiol Psychol. 1976 May; 90(5):453-9. PMID: 988061.
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    118. Ahlskog JE, Randall PK, Hoebel BG. Hupothalamic hyperphagia: dissociation from hyperphagia following destruction of noradrenergic neurons. Science. 1975 Oct 24; 190(4212):399-401. PMID: 1179221.
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    119. Riccio DC, Hodges LA, Randall PK. Retrograde amnesia produced by hypothermia in rats. J Comp Physiol Psychol. 1968 Dec; 66(3):618-22. PMID: 4305622.
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