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Katherine E. Twombley

TitleDirector, Division of Pediatric Nephrology
InstitutionMedical University of South Carolina
DepartmentPediatrics
AddressP.O. Box MSC 608
HE 428F
Clinical Science Bldg. - 96 Jonathan Lucas St.
Phone843-792-8904
Fax843-792-2033
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    Collapse Overview 
    Collapse keywords
    Children-s Health, Drug Studies, Pediatrics, Adolescents, Hypertension/ High Blood Pressure, Kidney, Transplant, Disease Prevention, Minorities, Vaccine

    Collapse ORNG Applications 
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Raina R, Krishnappa V, Sanchez-Kazi C, Quiroga A, Twombley KE, Mathias R, Lo M, Chakraborty R, Mahesh S, Steinke J, Bunchman T, Zaritsky J. Dextran-Sulfate Plasma Adsorption Lipoprotein Apheresis in Drug Resistant Primary Focal Segmental Glomerulosclerosis Patients: Results From a Prospective, Multicenter, Single-Arm Intervention Study. Front Pediatr. 2019; 7:454. PMID: 31850285.
      View in: PubMed
    2. Coffman Z, Steflik D, Chowdhury SM, Twombley K, Buckley J. Echocardiographic predictors of acute kidney injury in neonates with a patent ductus arteriosus. J Perinatol. 2019 Nov 25. PMID: 31767977.
      View in: PubMed
    3. Kocher M, Martin I, Twombley K, Kanter J, Jackson S, Self S, Hill J. An unusual ultrasound appearance of renal hemosiderosis in acute sickle cell nephropathy. Radiol Case Rep. 2020 Jan; 15(1):26-30. PMID: 31762862.
      View in: PubMed
    4. Vincent K, Murphy HJ, Ross JR, Twombley KE. Acute Kidney Injury Guidelines Are Associated With Improved Recognition and Follow-up for Neonatal Patients. Adv Neonatal Care. 2019 Sep 13. PMID: 31567184.
      View in: PubMed
    5. Murphy HJ, Eklund MJ, Hill J, Morella K, Cahill JB, Kiger JR, Twombley KE, Annibale DJ. Early continuous renal replacement therapy during infant extracorporeal life support is associated with decreased lung opacification. J Artif Organs. 2019 Dec; 22(4):286-293. PMID: 31342287.
      View in: PubMed
    6. Zahr RS, Yee ME, Weaver J, Twombley K, Matar RB, Aviles D, Sreedharan R, Rheault MN, Malatesta-Muncher R, Stone H, Srivastava T, Kapur G, Baddi P, Volovelsky O, Pelletier J, Gbadegesin R, Seeherunvong W, Patel HP, Greenbaum LA. Kidney biopsy findings in children with sickle cell disease: a Midwest Pediatric Nephrology Consortium study. Pediatr Nephrol. 2019 08; 34(8):1435-1445. PMID: 30945006.
      View in: PubMed
    7. Hendren EM, Reynolds ML, Mariani LH, Zee J, O'Shaughnessy MM, Oliverio AL, Moore NW, Hill-Callahan P, Rizk DV, Almanni S, Twombley KE, Herreshoff E, Nester CM, Hladunewich MA. Confidence in Women's Health: A Cross Border Survey of Adult Nephrologists. J Clin Med. 2019 Feb 03; 8(2). PMID: 30717445.
      View in: PubMed
    8. Nicoara O, Twombley K. Immunoglobulin A Nephropathy and Immunoglobulin A Vasculitis. Pediatr Clin North Am. 2019 02; 66(1):101-110. PMID: 30454736.
      View in: PubMed
    9. Mariani LH, Bomback AS, Canetta PA, Flessner MF, Helmuth M, Hladunewich MA, Hogan JJ, Kiryluk K, Nachman PH, Nast CC, Rheault MN, Rizk DV, Trachtman H, Wenderfer SE, Bowers C, Hill-Callahan P, Marasa M, Poulton CJ, Revell A, Vento S, Barisoni L, Cattran D, D'Agati V, Jennette JC, Klein JB, Laurin LP, Twombley K, Falk RJ, Gharavi AG, Gillespie BW, Gipson DS, Greenbaum LA, Holzman LB, Kretzler M, Robinson B, Smoyer WE, Guay-Woodford LM. CureGN Study Rationale, Design, and Methods: Establishing a Large Prospective Observational Study of Glomerular Disease. Am J Kidney Dis. 2019 02; 73(2):218-229. PMID: 30420158.
      View in: PubMed
    10. Oliverio AL, Zee J, Mariani LH, Reynolds ML, O'Shaughnessy M, Hendren EM, Alachkar N, Herreshoff E, Rizk DV, Nester CM, Steinke J, Twombley KE, Hladunewich MA. Renal Complications in Pregnancy Preceding Glomerulonephropathy Diagnosis. Kidney Int Rep. 2019 Jan; 4(1):159-162. PMID: 30596179.
      View in: PubMed
    11. Selewski DT, Ambruzs JM, Appel GB, Bomback AS, Matar RB, Cai Y, Cattran DC, Chishti AS, D'Agati VD, D'Alessandri-Silva CJ, Gbadegesin RA, Hogan JJ, Iragorri S, Jennette JC, Julian BA, Khalid M, Lafayette RA, Liapis H, Lugani F, Mansfield SA, Mason S, Nachman PH, Nast CC, Nester CM, Noone DG, Novak J, O'Shaughnessy MM, Reich HN, Rheault MN, Rizk DV, Saha MK, Sanghani NS, Sperati CJ, Sreedharan R, Srivastava T, Swiatecka-Urban A, Twombley K, Vasylyeva TL, Weaver DJ, Yin H, Zee J, Falk RJ, Gharavi AG, Gillespie BW, Gipson DS, Greenbaum LA, Holzman LB, Kretzler M, Robinson BM, Smoyer WE, Flessner M, Guay-Woodford LM, Kiryluk K. Clinical Characteristics and Treatment Patterns of Children and Adults With IgA Nephropathy or IgA Vasculitis: Findings From the CureGN Study. Kidney Int Rep. 2018 Nov; 3(6):1373-1384. PMID: 30450464.
      View in: PubMed
    12. Nazario M, Nicoara O, Becton L, Self S, Hill J, Mack E, Evans M, Twombley K. Safety and utility of surveillance biopsies in pediatric kidney transplant patients. Pediatr Transplant. 2018 06; 22(4):e13178. PMID: 29582530.
      View in: PubMed
    13. Murphy HJ, Cahill JB, Twombley KE, Annibale DJ, Kiger JR. Implementing a practice change: early initiation of continuous renal replacement therapy during neonatal extracorporeal life support standardizes care and improves short-term outcomes. J Artif Organs. 2018 Mar; 21(1):76-85. PMID: 29086091.
      View in: PubMed
    14. Murphy HJ, Cahill JB, Twombley KE, Kiger JR. Early Continuous Renal Replacement Therapy Improves Nutrition Delivery in Neonates During Extracorporeal Life Support. J Ren Nutr. 2018 01; 28(1):64-70. PMID: 28964639.
      View in: PubMed
    15. Misurac JM, VanDeVoorde RG, Kallash M, Iorember FM, Luckritz KE, Rheault MN, Jetton JG, Turman MA, Kapur G, Twombley KE, Hashmat S, Weaver DJ, Leiser JD, Nailescu C. Immunogenicity of Augmented Compared With Standard Dose Hepatitis B Vaccine in Pediatric Patients on Dialysis: a Midwest Pediatric Nephrology Consortium Study. Clin J Am Soc Nephrol. 2017 May 08; 12(5):772-778. PMID: 28270432.
      View in: PubMed
    16. Lewis K, Butts R, Antonio Quiros J, Hudspeth M, Twombley K, Savage A, Self S, Burnette A, Sun S. Autoimmune enteropathy and hepatitis in pediatric heart transplant recipient. Pediatr Transplant. 2017 Mar; 21(2). PMID: 28097735.
      View in: PubMed
    17. Kizilbash S, Claes D, Ashoor I, Chen A, Jandeska S, Matar RB, Misurac J, Sherbotie J, Twombley K, Verghese P. Bortezomib in the treatment of antibody-mediated rejection in pediatric kidney transplant recipients: A multicenter Midwest Pediatric Nephrology Consortium study. Pediatr Transplant. 2017 May; 21(3). PMID: 28092129.
      View in: PubMed
    18. Jordan CL, Taber DJ, Kyle MO, Connelly J, Pilch NW, Fleming J, Meadows HB, Bratton CF, Nadig SN, McGillicuddy JW, Chavin KD, Baliga PK, Shatat IF, Twombley K. Incidence, risk factors, and outcomes of opportunistic infections in pediatric renal transplant recipients. Pediatr Transplant. 2016 Feb; 20(1):44-8. PMID: 26576516.
      View in: PubMed
    19. Connelly J, Pilch N, Oliver M, Jordan C, Fleming J, Meadows H, Baliga P, Nadig S, Twombley K, Shatat I, Taber D. Prediction of medication non-adherence and associated outcomes in pediatric kidney transplant recipients. Pediatr Transplant. 2015 Aug; 19(5):555-62. PMID: 25917112.
      View in: PubMed
    20. Twombley K, Thach L, Ribeiro A, Joseph C, Seikaly M. Acute antibody-mediated rejection in pediatric kidney transplants: a single center experience. Pediatr Transplant. 2013 Nov; 17(7):E149-55. PMID: 23901848.
      View in: PubMed
    21. Corbin Bush N, Twombley K, Ahn J, Oliveira C, Arnold S, Maalouf NM, Sakhaee K. Prevalence and spot urine risk factors for renal stones in children taking topiramate. J Pediatr Urol. 2013 Dec; 9(6 Pt A):884-9. PMID: 23375465.
      View in: PubMed
    22. Baum M, Twombley K, Gattineni J, Joseph C, Wang L, Zhang Q, Dwarakanath V, Moe OW. Proximal tubule Na+/H+ exchanger activity in adult NHE8-/-, NHE3-/-, and NHE3-/-/NHE8-/- mice. Am J Physiol Renal Physiol. 2012 Dec 01; 303(11):F1495-502. PMID: 23054255.
      View in: PubMed
    23. Twombley K, Pokala H, Ardura MI, Harker-Murray P, Johnson-Welch SF, Weinberg A, Seikaly M. Intraventricular rituximab and systemic chemotherapy for treatment of central nervous system post-transplant lymphoproliferative disorder after kidney transplantation. Pediatr Transplant. 2012 Sep; 16(6):E201-9. PMID: 22646132.
      View in: PubMed
    24. Joseph C, Twombley K, Gattineni J, Zhang Q, Dwarakanath V, Baum M. Acid increases NHE8 surface expression and activity in NRK cells. Am J Physiol Renal Physiol. 2012 Feb 15; 302(4):F495-503. PMID: 22088432.
      View in: PubMed
    25. Baum M, Martin MG, Booth IW, Holmberg C, Twombley K, Zhang Q, Gattineni J, Moe O. Nucleotide sequence of the Na+/H+ exchanger-8 in patients with congenital sodium diarrhea. J Pediatr Gastroenterol Nutr. 2011 Nov; 53(5):474-7. PMID: 21666503.
      View in: PubMed
    26. Gattineni J, Twombley K, Goetz R, Mohammadi M, Baum M. Regulation of serum 1,25(OH)2 vitamin D3 levels by fibroblast growth factor 23 is mediated by FGF receptors 3 and 4. Am J Physiol Renal Physiol. 2011 Aug; 301(2):F371-7. PMID: 21561999.
      View in: PubMed
    27. Twombley K, Baum M, Gattineni J. Accidental and iatrogenic causes of acute kidney injury. Curr Opin Pediatr. 2011 Apr; 23(2):208-14. PMID: 21293274.
      View in: PubMed
    28. Habib S, Gattineni J, Twombley K, Baum M. Evidence that prenatal programming of hypertension by dietary protein deprivation is mediated by fetal glucocorticoid exposure. Am J Hypertens. 2011 Jan; 24(1):96-101. PMID: 20725051.
      View in: PubMed
    29. Twombley K, Gattineni J, Bobulescu IA, Dwarakanath V, Baum M. Effect of metabolic acidosis on neonatal proximal tubule acidification. Am J Physiol Regul Integr Comp Physiol. 2010 Nov; 299(5):R1360-8. PMID: 20720175.
      View in: PubMed
    30. Gattineni J, Bates C, Twombley K, Dwarakanath V, Robinson ML, Goetz R, Mohammadi M, Baum M. FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1. Am J Physiol Renal Physiol. 2009 Aug; 297(2):F282-91. PMID: 19515808.
      View in: PubMed
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