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Institution

Jeffrey A. Jones

Title
InstitutionMedical University of South Carolina
DepartmentSurgery
AddressP.O. Box MSC 778
625
114 Doughty St.
Phone843-792-0062
Fax843-876-5187
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Akerman AW, Blanding WM, Stroud RE, Nadeau EK, Mukherjee R, Ruddy JM, Zile MR, Ikonomidis JS, Jones JA. Elevated Wall Tension Leads to Reduced miR-133a in the Thoracic Aorta by Exosome Release. J Am Heart Assoc. 2019 Jan 08; 8(1):e010332. PMID: 30572760.
      View in: PubMed
    2. McDonald LT, Zile MR, Zhang Y, Van Laer AO, Baicu CF, Stroud RE, Jones JA, LaRue AC, Bradshaw AD. Increased macrophage-derived SPARC precedes collagen deposition in myocardial fibrosis. Am J Physiol Heart Circ Physiol. 2018 07 01; 315(1):H92-H100. PMID: 29522370.
      View in: PubMed
    3. Akerman AW, Stroud RE, Barrs RW, Grespin RT, McDonald LT, LaRue RAC, Mukherjee R, Ikonomidis JS, Jones JA, Ruddy JM. Elevated Wall Tension Initiates Interleukin-6 Expression and Abdominal Aortic Dilation. Ann Vasc Surg. 2018 Jan; 46:193-204. PMID: 29107003.
      View in: PubMed
    4. Jones JA. Oxidative stress in bicuspid aortic valve-related aortopathy: Hand-me-downs and yoga pants. J Thorac Cardiovasc Surg. 2017 Nov; 154(5):1764-1765. PMID: 28689786.
      View in: PubMed
    5. Tian Y, Zhang W, Sun J, Zhai H, Yu Y, Qi X, Jones JA, Zhong H. A reproducible swine model of proximal descending thoracic aortic aneurysm created with intra-adventitial application of elastase. J Vasc Surg. 2018 01; 67(1):300-308.e2. PMID: 28479097.
      View in: PubMed
    6. Ruddy JM, Akerman AW, Kimbrough D, Nadeau EK, Stroud RE, Mukherjee R, Ikonomidis JS, Jones JA. Differential hypertensive protease expression in the thoracic versus abdominal aorta. J Vasc Surg. 2017 11; 66(5):1543-1552. PMID: 28034583.
      View in: PubMed
    7. Ikonomidis JS, Nadeau EK, Akerman AW, Stroud RE, Mukherjee R, Jones JA. Regulation of membrane type-1 matrix metalloproteinase activity and intracellular localization in clinical thoracic aortic aneurysms. J Thorac Cardiovasc Surg. 2017 Mar; 153(3):537-546. PMID: 27923483.
      View in: PubMed
    8. Ruddy JM, Ikonomidis JS, Jones JA. Multidimensional Contribution of Matrix Metalloproteinases to Atherosclerotic Plaque Vulnerability: Multiple Mechanisms of Inhibition to Promote Stability. J Vasc Res. 2016; 53(1-2):1-16. PMID: 27327039.
      View in: PubMed
    9. Jones JA. Editorial Commentary: Understanding Marfan syndrome, or "how not to invent the light bulb". Trends Cardiovasc Med. 2016 07; 26(5):429-32. PMID: 27013137.
      View in: PubMed
    10. Renaud L, Harris LG, Mani SK, Kasiganesan H, Chou JC, Baicu CF, Van Laer A, Akerman AW, Stroud RE, Jones JA, Zile MR, Menick DR. HDACs Regulate miR-133a Expression in Pressure Overload-Induced Cardiac Fibrosis. Circ Heart Fail. 2015 Nov; 8(6):1094-104. PMID: 26371176.
      View in: PubMed
    11. McDonald LT, Russell DL, Kelly RR, Xiong Y, Motamarry A, Patel RK, Jones JA, Watson PM, Turner DP, Watson DK, Soloff AC, Findlay VJ, LaRue AC. Hematopoietic stem cell-derived cancer-associated fibroblasts are novel contributors to the pro-tumorigenic microenvironment. Neoplasia. 2015 May; 17(5):434-48. PMID: 26025666.
      View in: PubMed
    12. Wheeler JB, Mukherjee R, Stroud RE, Jones JA, Ikonomidis JS. Relation of murine thoracic aortic structural and cellular changes with aging to passive and active mechanical properties. J Am Heart Assoc. 2015 Feb 25; 4(3):e001744. PMID: 25716945.
      View in: PubMed
    13. Jones JA. Invited commentary. Ann Thorac Surg. 2015 Jan; 99(1):71. PMID: 25555935.
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    14. Kavarana MN, Jones JA, Stroud RE, Bradley SM, Ikonomidis JS, Mukherjee R. Pulmonary arteriovenous malformations after the superior cavopulmonary shunt: mechanisms and clinical implications. Expert Rev Cardiovasc Ther. 2014 Jun; 12(6):703-13. PMID: 24758411.
      View in: PubMed
    15. Zile MR, Baicu CF, Stroud RE, Van Laer AO, Jones JA, Patel R, Mukherjee R, Spinale FG. Mechanistic relationship between membrane type-1 matrix metalloproteinase and the myocardial response to pressure overload. Circ Heart Fail. 2014 Mar 01; 7(2):340-50. PMID: 24395927.
      View in: PubMed
    16. Wheeler JB, Ikonomidis JS, Jones JA. Connective tissue disorders and cardiovascular complications: the indomitable role of transforming growth factor-beta signaling. Adv Exp Med Biol. 2014; 802:107-27. PMID: 24443024.
      View in: PubMed
    17. Eckhouse SR, Logdon CB, Oelsen JM, Patel RK, Rice AD, Stroud RE, Wince WB, Mukherjee R, Spinale FG, Ikonomidis JS, Jones JA. Reproducible porcine model of thoracic aortic aneurysm. Circulation. 2013 Sep 10; 128(11 Suppl 1):S186-93. PMID: 24030405.
      View in: PubMed
    18. Kavarana MN, Mukherjee R, Eckhouse SR, Rawls WF, Logdon C, Stroud RE, Patel RK, Nadeau EK, Spinale FG, Graham EM, Forbus GA, Bradley SM, Ikonomidis JS, Jones JA. Pulmonary artery endothelial cell phenotypic alterations in a large animal model of pulmonary arteriovenous malformations after the Glenn shunt. Ann Thorac Surg. 2013 Oct; 96(4):1442-1449. PMID: 23968766.
      View in: PubMed
    19. Ruddy JM, Jones JA, Ikonomidis JS. Pathophysiology of thoracic aortic aneurysm (TAA): is it not one uniform aorta? Role of embryologic origin. Prog Cardiovasc Dis. 2013 Jul-Aug; 56(1):68-73. PMID: 23993239.
      View in: PubMed
    20. Ikonomidis JS, Ivey CR, Wheeler JB, Akerman AW, Rice A, Patel RK, Stroud RE, Shah AA, Hughes CG, Ferrari G, Mukherjee R, Jones JA. Plasma biomarkers for distinguishing etiologic subtypes of thoracic aortic aneurysm disease. J Thorac Cardiovasc Surg. 2013 May; 145(5):1326-33. PMID: 23312977.
      View in: PubMed
    21. Eckhouse SR, Akerman AW, Logdon CB, Oelsen JM, O'Quinn EC, Nadeau EK, Stroud RE, Mukherjee R, Jones JA, Spinale FG. Differential membrane type 1 matrix metalloproteinase substrate processing with ischemia-reperfusion: relationship to interstitial microRNA dynamics and myocardial function. J Thorac Cardiovasc Surg. 2013 Jan; 145(1):267-275, 277.e1-4; discussion 275-7. PMID: 23102905.
      View in: PubMed
    22. Eckhouse SR, Jones JA, Spinale FG. Gene targeting in ischemic heart disease and failure: translational and clinical studies. Biochem Pharmacol. 2013 Jan 01; 85(1):1-11. PMID: 22935384.
      View in: PubMed
    23. Zile MR, Baicu CF, Stroud RE, Van Laer A, Arroyo J, Mukherjee R, Jones JA, Spinale FG. Pressure overload-dependent membrane type 1-matrix metalloproteinase induction: relationship to LV remodeling and fibrosis. Am J Physiol Heart Circ Physiol. 2012 Apr 01; 302(7):H1429-37. PMID: 22287584.
      View in: PubMed
    24. Ikonomidis JS, Ruddy JM, Benton SM, Arroyo J, Brinsa TA, Stroud RE, Zeeshan A, Bavaria JE, Gorman JH, Gorman RC, Spinale FG, Jones JA. Aortic dilatation with bicuspid aortic valves: cusp fusion correlates to matrix metalloproteinases and inhibitors. Ann Thorac Surg. 2012 Feb; 93(2):457-63. PMID: 22206960.
      View in: PubMed
    25. Jones JA, Stroud RE, O'Quinn EC, Black LE, Barth JL, Elefteriades JA, Bavaria JE, Gorman JH, Gorman RC, Spinale FG, Ikonomidis JS. Selective microRNA suppression in human thoracic aneurysms: relationship of miR-29a to aortic size and proteolytic induction. Circ Cardiovasc Genet. 2011 Dec; 4(6):605-13. PMID: 22010139.
      View in: PubMed
    26. Theruvath TP, Jones JA, Ikonomidis JS. Matrix metalloproteinases and descending aortic aneurysms: parity, disparity, and switch. J Card Surg. 2012 Jan; 27(1):81-90. PMID: 21958052.
      View in: PubMed
    27. Jones JA, Ruddy JM, Bouges S, Zavadzkas JA, Brinsa TA, Stroud RE, Mukherjee R, Spinale FG, Ikonomidis JS. Alterations in membrane type-1 matrix metalloproteinase abundance after the induction of thoracic aortic aneurysm in a murine model. Am J Physiol Heart Circ Physiol. 2010 Jul; 299(1):H114-24. PMID: 20418476.
      View in: PubMed
    28. Jones JA, Zavadzkas JA, Chang EI, Sheats N, Koval C, Stroud RE, Spinale FG, Ikonomidis JS. Cellular phenotype transformation occurs during thoracic aortic aneurysm development. J Thorac Cardiovasc Surg. 2010 Sep; 140(3):653-9. PMID: 20219212.
      View in: PubMed
    29. Jones JA, Ikonomidis JS. The pathogenesis of aortopathy in Marfan syndrome and related diseases. Curr Cardiol Rep. 2010 Mar; 12(2):99-107. PMID: 20425163.
      View in: PubMed
    30. Ruddy JM, Jones JA, Stroud RE, Mukherjee R, Spinale FG, Ikonomidis JS. Differential effects of mechanical and biological stimuli on matrix metalloproteinase promoter activation in the thoracic aorta. Circulation. 2009 Sep 15; 120(11 Suppl):S262-8. PMID: 19752377.
      View in: PubMed
    31. Jones JA, Beck C, Barbour JR, Zavadzkas JA, Mukherjee R, Spinale FG, Ikonomidis JS. Alterations in aortic cellular constituents during thoracic aortic aneurysm development: myofibroblast-mediated vascular remodeling. Am J Pathol. 2009 Oct; 175(4):1746-56. PMID: 19729479.
      View in: PubMed
    32. Ruddy JM, Jones JA, Stroud RE, Mukherjee R, Spinale FG, Ikonomidis JS. Differential effect of wall tension on matrix metalloproteinase promoter activation in the thoracic aorta. J Surg Res. 2010 May 15; 160(2):333-9. PMID: 19375723.
      View in: PubMed
    33. Jones JA, Spinale FG, Ikonomidis JS. Transforming growth factor-beta signaling in thoracic aortic aneurysm development: a paradox in pathogenesis. J Vasc Res. 2009; 46(2):119-37. PMID: 18765947.
      View in: PubMed
    34. Ruddy JM, Jones JA, Spinale FG, Ikonomidis JS. Regional heterogeneity within the aorta: relevance to aneurysm disease. J Thorac Cardiovasc Surg. 2008 Nov; 136(5):1123-30. PMID: 19026791.
      View in: PubMed
    35. Jones JA, Barbour JR, Stroud RE, Bouges S, Stephens SL, Spinale FG, Ikonomidis JS. Altered transforming growth factor-beta signaling in a murine model of thoracic aortic aneurysm. J Vasc Res. 2008; 45(6):457-68. PMID: 18434745.
      View in: PubMed
    36. Marchesini N, Jones JA, Hannun YA. Confluence induced threonine41/serine45 phospho-beta-catenin dephosphorylation via ceramide-mediated activation of PP1cgamma. Biochim Biophys Acta. 2007 Dec; 1771(12):1418-28. PMID: 17996206.
      View in: PubMed
    37. Jones JA, Stroud RE, Kaplan BS, Leone AM, Bavaria JE, Gorman JH, Gorman RC, Ikonomidis JS. Differential protein kinase C isoform abundance in ascending aortic aneurysms from patients with bicuspid versus tricuspid aortic valves. Circulation. 2007 Sep 11; 116(11 Suppl):I144-9. PMID: 17846295.
      View in: PubMed
    38. Ikonomidis JS, Jones JA, Barbour JR, Stroud RE, Clark LL, Kaplan BS, Zeeshan A, Bavaria JE, Gorman JH, Spinale FG, Gorman RC. Expression of matrix metalloproteinases and endogenous inhibitors within ascending aortic aneurysms of patients with bicuspid or tricuspid aortic valves. J Thorac Cardiovasc Surg. 2007 Apr; 133(4):1028-36. PMID: 17382648.
      View in: PubMed
    39. Jones JA, Barbour JR, Lowry AS, Bouges S, Beck C, McClister DM, Mukherjee R, Ikonomidis JS. Spatiotemporal expression and localization of matrix metalloproteinas-9 in a murine model of thoracic aortic aneurysm. J Vasc Surg. 2006 Dec; 44(6):1314-21. PMID: 17145436.
      View in: PubMed
    40. Barbour JR, Stroud RE, Lowry AS, Clark LL, Leone AM, Jones JA, Spinale FG, Ikonomidis JS. Temporal disparity in the induction of matrix metalloproteinases and tissue inhibitors of metalloproteinases after thoracic aortic aneurysm formation. J Thorac Cardiovasc Surg. 2006 Oct; 132(4):788-95. PMID: 17000289.
      View in: PubMed
    41. Ikonomidis JS, Jones JA, Barbour JR, Stroud RE, Clark LL, Kaplan BS, Zeeshan A, Bavaria JE, Gorman JH, Spinale FG, Gorman RC. Expression of matrix metalloproteinases and endogenous inhibitors within ascending aortic aneurysms of patients with Marfan syndrome. Circulation. 2006 Jul 04; 114(1 Suppl):I365-70. PMID: 16820601.
      View in: PubMed
    42. Jones JA, Rawles R, Hannun YA. Identification of a novel phosphatidic acid binding domain in protein phosphatase-1. Biochemistry. 2005 Oct 11; 44(40):13235-45. PMID: 16201749.
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    43. Novgorodov SA, Szulc ZM, Luberto C, Jones JA, Bielawski J, Bielawska A, Hannun YA, Obeid LM. Positively charged ceramide is a potent inducer of mitochondrial permeabilization. J Biol Chem. 2005 Apr 22; 280(16):16096-105. PMID: 15722351.
      View in: PubMed
    44. Jones JA, Hannun YA. Tight binding inhibition of protein phosphatase-1 by phosphatidic acid. Specificity of inhibition by the phospholipid. J Biol Chem. 2002 May 03; 277(18):15530-8. PMID: 11856740.
      View in: PubMed
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