Gonzalo J. Revuelta

Title
InstitutionMedical University of South Carolina
DepartmentNeurology
AddressP.O. Box MSC 108
1
208-B Rutledge Ave. - 208-B Rutledge Ave.
Phone843-792-7262
Fax843-792-1751
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    I am a clinician scientist with training as a movement disorder neurologist and deep brain stimulation specialist. My primary research focus is the development of neuromodulation therapies for freezing of gait (FoG) in patients with Parkinson’s disease (PD). I initiated a research program utilizing diffusion kurtosis tractography to characterize the locomotor pathway changes in FoG patients, and developing surrogate markers of FoG severity through gait analysis. This research has been expanded to focus on differences in the pathways in patients that are dopa un-responsive, and correlating these changes with findings on gait analysis. I am experienced in the design and implementation of clinical trials through a number of investigator initiated pilot trials of therapeutics and participation in national consortia led multicenter clinical trials, including investigation for multiple neuromodulation modalities.
    Collapse keywords
    Movement Disorders, Drug Studies, Parkinsons

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Brooks M, Carter E, Quiros A, Revuelta G. Levodopa-Carbidopa Intestinal Gel in Pediatric Parkinson's Disease. Mov Disord Clin Pract. 2020 Aug; 7(6):693-694. PMID: 32775517.
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    2. Vitek JL, Jain R, Chen L, Tröster AI, Schrock LE, House PA, Giroux ML, Hebb AO, Farris SM, Whiting DM, Leichliter TA, Ostrem JL, San Luciano M, Galifianakis N, Verhagen Metman L, Sani S, Karl JA, Siddiqui MS, Tatter SB, Ul Haq I, Machado AG, Gostkowski M, Tagliati M, Mamelak AN, Okun MS, Foote KD, Moguel-Cobos G, Ponce FA, Pahwa R, Nazzaro JM, Buetefisch CM, Gross RE, Luca CC, Jagid JR, Revuelta GJ, Takacs I, Pourfar MH, Mogilner AY, Duker AP, Mandybur GT, Rosenow JM, Cooper SE, Park MC, Khandhar SM, Sedrak M, Phibbs FT, Pilitsis JG, Uitti RJ, Starr PA. Subthalamic nucleus deep brain stimulation with a multiple independent constant current-controlled device in Parkinson's disease (INTREPID): a multicentre, double-blind, randomised, sham-controlled study. Lancet Neurol. 2020 06; 19(6):491-501. PMID: 32470421.
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    3. Lench DH, Embry A, Hydar A, Hanlon CA, Revuelta G. Increased on-state cortico-mesencephalic functional connectivity in Parkinson disease with freezing of gait. Parkinsonism Relat Disord. 2020 03; 72:31-36. PMID: 32097881.
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    4. Revuelta G, McGill C, Jensen JH, Bonilha L. Characterizing Thalamo-Cortical Structural Connectivity in Essential Tremor with Diffusional Kurtosis Imaging Tractography. Tremor Other Hyperkinet Mov (N Y). 2019; 9. PMID: 31534829.
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    5. Chhatbar PY, Kautz SA, Takacs I, Rowland NC, Revuelta GJ, George MS, Bikson M, Feng W. Evidence of transcranial direct current stimulation-generated electric fields at subthalamic level in human brain in vivo. Brain Stimul. 2018 Jul - Aug; 11(4):727-733. PMID: 29576498.
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    6. Fryml LD, Williams KR, Pelic CG, Fox J, Sahlem G, Robert S, Revuelta GJ, Short EB. The Role of Amantadine Withdrawal in 3 Cases of Treatment-Refractory Altered Mental Status. J Psychiatr Pract. 2017 05; 23(3):191-199. PMID: 28492457.
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    7. Williams NR, Sahlem G, Pannu J, Takacs I, Short B, Revuelta G, George MS. Neuroversion: using electroconvulsive therapy as a bridge to deep brain stimulation implantation. Neurocase. 2017 Feb; 23(1):26-30. PMID: 28376692.
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    8. Badran BW, Glusman CE, Austelle CW, Jenkins S, DeVries WH, Galbraith V, Thomas T, Adams TG, George MS, Revuelta GJ. A Double-Blind, Sham-Controlled Pilot Trial of Pre-Supplementary Motor Area (Pre-SMA) 1?Hz rTMS to Treat Essential Tremor. Brain Stimul. 2016 Nov - Dec; 9(6):945-947. PMID: 27567469.
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    9. Factor SA, Hatcher-Martin JM, Morse AS, Nocera JR, Revuelta GJ. Freezing of gait that disappears: Should there be rest before rehab? Parkinsonism Relat Disord. 2016 07; 28:169-70. PMID: 27103479.
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    10. Revuelta GJ, Embry A, Elm JJ, Gregory C, Delambo A, Kautz S, Hinson VK. Pilot study of atomoxetine in patients with Parkinson's disease and dopa-unresponsive Freezing of Gait. Transl Neurodegener. 2015; 4:24. PMID: 26693006.
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    11. Williams NR, Hopkins TR, Short EB, Sahlem GL, Snipes J, Revuelta GJ, George MS, Takacs I. Reward circuit DBS improves Parkinson's gait along with severe depression and OCD. Neurocase. 2016; 22(2):201-4. PMID: 26644268.
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    12. Taylor JJ, Larrew T, Omole A, Roberts M, Kornegay A, Kornegay K, Yamada L, Revuelta GJ, Sohn M, Hughes T, Edwards JC. The feasibility of establishing a free clinic for uninsured patients with neurologic disorders. Neurol Clin Pract. 2015 Aug; 5(4):302-308. PMID: 26336631.
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    13. Finsterer J, Maeztu C, Revuelta GJ, Reichel G, Truong D. Collum-caput (COL-CAP) concept for conceptual anterocollis, anterocaput, and forward sagittal shift. J Neurol Sci. 2015 Aug 15; 355(1-2):37-43. PMID: 26088286.
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    14. Finsterer J, Revuelta GJ. Anterocollis and anterocaput. Clin Neurol Neurosurg. 2014 Dec; 127:44-53. PMID: 25459242.
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    15. Revuelta GJ, Montilla J, Benatar M, Freeman A, Wichmann T, Jinnah HA, Delong MR, Factor SA. An ¹8F-FDG PET study of cervical muscle in parkinsonian anterocollis. J Neurol Sci. 2014 May 15; 340(1-2):174-7. PMID: 24725739.
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    16. Hinson VK, Delambo AL, Embry AE, Gregory C, Gaines K, Salak V and Revuelta GJ. . Forced Exercise for Freezing of Gait in Post STN DBS Parkinson’s Disease Patients. Journal of Alzheimer’s Disease and Parkinsonism. 2014; 6(4):171.
    17. Revuelta GJ, Uthayathas S, Wahlquist AE, Factor SA, Papa SM. Non-human primate FOG develops with advanced parkinsonism induced by MPTP Treatment. Exp Neurol. 2012 Oct; 237(2):464-9. PMID: 22967858.
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    18. Revuelta GJ. Anterocollis and camptocormia in parkinsonism: a current assessment. Curr Neurol Neurosci Rep. 2012 Aug; 12(4):386-91. PMID: 22639084.
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    19. Revuelta GJ, Benatar M, Freeman A, Wichmann T, Jinnah HA, DeLong MR, Factor SA. Clinical subtypes of anterocollis in parkinsonian syndromes. J Neurol Sci. 2012 Apr 15; 315(1-2):100-3. PMID: 22133481.
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    20. Aia PG, Revuelta GJ, Cloud LJ, Factor SA. Tardive dyskinesia. Curr Treat Options Neurol. 2011 Jun; 13(3):231-41. PMID: 21365202.
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    21. Revuelta GJ, Wilmot GR. Therapeutic interventions in the primary hereditary ataxias. Curr Treat Options Neurol. 2010 Jul; 12(4):257-73. PMID: 20842586.
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    22. Revuelta GJ, Testa C, Greene JG. Writer's cramp: a potential early feature of Huntington's disease. Mov Disord. 2010 Apr 30; 25(6):785-6. PMID: 20437545.
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    23. Revuelta GJ, Lippa CF. Dementia with Lewy bodies and Parkinson's disease dementia may best be viewed as two distinct entities. Int Psychogeriatr. 2009 Apr; 21(2):213-6. PMID: 19173761.
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    24. Revuelta GJ, Rosso A, Lippa CF. Association between progranulin and beta-amyloid in dementia with Lewy bodies. Am J Alzheimers Dis Other Demen. 2008 Oct-Nov; 23(5):488-93. PMID: 18955727.
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    25. Revuelta GJ, Rosso A, Lippa CF. Neuritic pathology as a correlate of synaptic loss in dementia with lewy bodies. Am J Alzheimers Dis Other Demen. 2008 Feb-Mar; 23(1):97-102. PMID: 18276962.
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