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Glenn Prazere Lobo

Title
InstitutionMedical University of South Carolina
DepartmentNephrology
AddressP.O. Box MSC 629
Drug Discovery Building, Office 513
Drug Discovery Building - 70 President St.
Phone843-876-2371
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Zuo X, Lobo G, Fulmer D, Guo L, Dang Y, Su Y, Ilatovskaya DV, Nihalani D, Rohrer B, Body SC, Norris RA, Lipschutz JH. The exocyst acting through the primary cilium is necessary for renal ciliogenesis, cystogenesis, and tubulogenesis. J Biol Chem. 2019 Apr 26; 294(17):6710-6718. PMID: 30824539.
      View in: PubMed
    2. Lobo GP, Pauer G, Lipschutz JH, Hagstrom SA. The Retinol-Binding Protein Receptor 2 (Rbpr2) Is Required for Photoreceptor Survival and Visual Function in the Zebrafish. Adv Exp Med Biol. 2018; 1074:569-576. PMID: 29721989.
      View in: PubMed
    3. Shi Y, Su Y, Lipschutz JH, Lobo GP. Zebrafish as models to study ciliopathies of the eye and kidney. Clin Nephrol Res. 2017 Dec; 1(1):6-9. PMID: 29553143.
      View in: PubMed
    4. Shi Y, Obert E, Rahman B, Rohrer B, Lobo GP. The Retinol Binding Protein Receptor 2 (Rbpr2) is required for Photoreceptor Outer Segment Morphogenesis and Visual Function in Zebrafish. Sci Rep. 2017 11 24; 7(1):16207. PMID: 29176573.
      View in: PubMed
    5. Lobo GP, Fulmer D, Guo L, Zuo X, Dang Y, Kim SH, Su Y, George K, Obert E, Fogelgren B, Nihalani D, Norris RA, Rohrer B, Lipschutz JH. The exocyst is required for photoreceptor ciliogenesis and retinal development. J Biol Chem. 2017 09 08; 292(36):14814-14826. PMID: 28729419.
      View in: PubMed
    6. Daniele LL, Emran F, Lobo GP, Gaivin RJ, Perkins BD. Mutation of wrb, a Component of the Guided Entry of Tail-Anchored Protein Pathway, Disrupts Photoreceptor Synapse Structure and Function. Invest Ophthalmol Vis Sci. 2016 06 01; 57(7):2942-54. PMID: 27273592.
      View in: PubMed
    7. Lobo GP, Au A, Kiser PD, Hagstrom SA. Involvement of Endoplasmic Reticulum Stress in TULP1 Induced Retinal Degeneration. PLoS One. 2016; 11(3):e0151806. PMID: 26987071.
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    8. Lobo GP, Ebke LA, Au A, Hagstrom SA. TULP1 Missense Mutations Induces the Endoplasmic Reticulum Unfolded Protein Response Stress Complex (ER-UPR). Adv Exp Med Biol. 2016; 854:223-30. PMID: 26427415.
      View in: PubMed
    9. Widjaja-Adhi MA, Lobo GP, Golczak M, Von Lintig J. A genetic dissection of intestinal fat-soluble vitamin and carotenoid absorption. Hum Mol Genet. 2015 Jun 01; 24(11):3206-19. PMID: 25701869.
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    10. Levi L, Lobo G, Doud MK, von Lintig J, Seachrist D, Tochtrop GP, Noy N. Genetic ablation of the fatty acid-binding protein FABP5 suppresses HER2-induced mammary tumorigenesis. Cancer Res. 2013 Aug 01; 73(15):4770-80. PMID: 23722546.
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    11. Lobo GP, Amengual J, Baus D, Shivdasani RA, Taylor D, von Lintig J. Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX. J Biol Chem. 2013 Mar 29; 288(13):9017-27. PMID: 23393141.
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    12. Lobo GP, Isken A, Hoff S, Babino D, von Lintig J. BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway. Development. 2012 Aug; 139(16):2966-77. PMID: 22764054.
      View in: PubMed
    13. Lobo GP, Amengual J, Palczewski G, Babino D, von Lintig J. Mammalian carotenoid-oxygenases: key players for carotenoid function and homeostasis. Biochim Biophys Acta. 2012 Jan; 1821(1):78-87. PMID: 21569862.
      View in: PubMed
    14. Amengual J, Lobo GP, Golczak M, Li HN, Klimova T, Hoppel CL, Wyss A, Palczewski K, von Lintig J. A mitochondrial enzyme degrades carotenoids and protects against oxidative stress. FASEB J. 2011 Mar; 25(3):948-59. PMID: 21106934.
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    15. Lobo GP, Amengual J, Li HN, Golczak M, Bonet ML, Palczewski K, von Lintig J. Beta,beta-carotene decreases peroxisome proliferator receptor gamma activity and reduces lipid storage capacity of adipocytes in a beta,beta-carotene oxygenase 1-dependent manner. J Biol Chem. 2010 Sep 03; 285(36):27891-9. PMID: 20573961.
      View in: PubMed
    16. Lobo GP, Hessel S, Eichinger A, Noy N, Moise AR, Wyss A, Palczewski K, von Lintig J. ISX is a retinoic acid-sensitive gatekeeper that controls intestinal beta,beta-carotene absorption and vitamin A production. FASEB J. 2010 Jun; 24(6):1656-66. PMID: 20061533.
      View in: PubMed
    17. Moise AR, Lobo GP, Erokwu B, Wilson DL, Peck D, Alvarez S, Domínguez M, Alvarez R, Flask CA, de Lera AR, von Lintig J, Palczewski K. Increased adiposity in the retinol saturase-knockout mouse. FASEB J. 2010 Apr; 24(4):1261-70. PMID: 19940255.
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    18. Moise AR, Alvarez S, Domínguez M, Alvarez R, Golczak M, Lobo GP, von Lintig J, de Lera AR, Palczewski K. Activation of retinoic acid receptors by dihydroretinoids. Mol Pharmacol. 2009 Dec; 76(6):1228-37. PMID: 19770350.
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    19. Lobo GP, Waite KA, Planchon SM, Romigh T, Nassif NT, Eng C. Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function. Hum Mol Genet. 2009 Aug 01; 18(15):2851-62. PMID: 19457929.
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    20. Ni Y, Zbuk KM, Sadler T, Patocs A, Lobo G, Edelman E, Platzer P, Orloff MS, Waite KA, Eng C. Germline mutations and variants in the succinate dehydrogenase genes in Cowden and Cowden-like syndromes. Am J Hum Genet. 2008 Aug; 83(2):261-8. PMID: 18678321.
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    21. Lobo GP, Waite KA, Planchon SM, Romigh T, Houghton JA, Eng C. ATP modulates PTEN subcellular localization in multiple cancer cell lines. Hum Mol Genet. 2008 Sep 15; 17(18):2877-85. PMID: 18579579.
      View in: PubMed
    22. Nassif NT, Lobo GP, Wu X, Henderson CJ, Morrison CD, Eng C, Jalaludin B, Segelov E. PTEN mutations are common in sporadic microsatellite stable colorectal cancer. Oncogene. 2004 Jan 15; 23(2):617-28. PMID: 14724591.
      View in: PubMed
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