Last Name

Erin A. McClure

InstitutionMedical University of South Carolina
DepartmentPsychiatry and Behavioral Sciences
AddressP.O. Box MSC 861
67 President St.
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    Dr. McClure’s research interests and activities involve the study of relapse, withdrawal, craving, and treatment for nicotine and cannabis dependence through the use of outpatient, laboratory-based studies, as well as clinical trials assessing pharmacological and behavioral interventions in both adolescents and adults. Dr. McClure is also interested in the utilization of different technology outlets to conduct fine-grained analyses of the process of relapse to inform treatment efforts and deliver interventions in real-time.

    Collapse keywords
    smoking cessation, nicotine dependence, mobile health, relapse, pharmacotherapy, smoking, adolescent

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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Tomko RL, Gray KM, Oppenheimer SR, Wahlquist AE, McClure EA. Using REDCap for ambulatory assessment: Implementation in a clinical trial for smoking cessation to augment in-person data collection. Am J Drug Alcohol Abuse. 2018 Mar 07; 1-16. PMID: 29513609.
      View in: PubMed
    2. Squeglia LM, Tomko RL, Baker NL, McClure EA, Book GA, Gray KM. The effect of N-acetylcysteine on alcohol use during a cannabis cessation trial. Drug Alcohol Depend. 2018 Apr 01; 185:17-22. PMID: 29413434.
      View in: PubMed
    3. Tomko RL, Baker NL, McClure EA, Sonne SC, McRae-Clark AL, Sherman BJ, Gray KM. Incremental validity of estimated cannabis grams as a predictor of problems and cannabinoid biomarkers: Evidence from a clinical trial. Drug Alcohol Depend. 2018 Jan 01; 182:1-7. PMID: 29112827.
      View in: PubMed
    4. Buchanan C, Nahhas GJ, Guille C, Cummings KM, Wheeler C, McClure EA. Tobacco Use Prevalence and Outcomes Among Perinatal Patients Assessed Through an "Opt-out" Cessation and Follow-Up Clinical Program. Matern Child Health J. 2017 Sep; 21(9):1790-1797. PMID: 28702864.
      View in: PubMed
    5. Hser YI, Mooney LJ, Huang D, Zhu Y, Tomko RL, McClure E, Chou CP, Gray KM. Reductions in cannabis use are associated with improvements in anxiety, depression, and sleep quality, but not quality of life. J Subst Abuse Treat. 2017 Oct; 81:53-58. PMID: 28847455.
      View in: PubMed
    6. Gray KM, Sonne SC, McClure EA, Ghitza UE, Matthews AG, McRae-Clark AL, Carroll KM, Potter JS, Wiest K, Mooney LJ, Hasson A, Walsh SL, Lofwall MR, Babalonis S, Lindblad RW, Sparenborg S, Wahle A, King JS, Baker NL, Tomko RL, Haynes LF, Vandrey RG, Levin FR. A randomized placebo-controlled trial of N-acetylcysteine for cannabis use disorder in adults. Drug Alcohol Depend. 2017 Aug 01; 177:249-257. PMID: 28623823.
      View in: PubMed
    7. McClure EA, King JS, Wahle A, Matthews AG, Sonne SC, Lofwall MR, McRae-Clark AL, Ghitza UE, Martinez M, Cloud K, Virk HS, Gray KM. Comparing adult cannabis treatment-seekers enrolled in a clinical trial with national samples of cannabis users in the United States. Drug Alcohol Depend. 2017 07 01; 176:14-20. PMID: 28511033.
      View in: PubMed
    8. Tomko RL, Saladin ME, McClure EA, Squeglia LM, Carpenter MJ, Tiffany ST, Baker NL, Gray KM. Alcohol consumption as a predictor of reactivity to smoking and stress cues presented in the natural environment of smokers. Psychopharmacology (Berl). 2017 Feb; 234(3):427-435. PMID: 27838746.
      View in: PubMed
    9. W Adams Z, McClure EA, Gray KM, Danielson CK, Treiber FA, Ruggiero KJ. Mobile devices for the remote acquisition of physiological and behavioral biomarkers in psychiatric clinical research. J Psychiatr Res. 2017 02; 85:1-14. PMID: 27814455.
      View in: PubMed
    10. Lévesque A, Campbell AN, Pavlicova M, Hu MC, Walker R, McClure EA, Ghitza UE, Bailey G, Stitzer M, Nunes EV. Coping strategies as a mediator of internet-delivered psychosocial treatment: Secondary analysis from a NIDA CTN multisite effectiveness trial. Addict Behav. 2017 Feb; 65:74-80. PMID: 27776269.
      View in: PubMed
    11. Squeglia LM, Baker NL, McClure EA, Tomko RL, Adisetiyo V, Gray KM. Alcohol use during a trial of N-acetylcysteine for adolescent marijuana cessation. Addict Behav. 2016 Dec; 63:172-7. PMID: 27521979; PMCID: PMC4993655 [Available on 12/01/17].
    12. Flanagan JC, Hakes JK, McClure EA, Snead AL, Back SE. Effects of intimate partner violence, PTSD, and alcohol use on cigarette smoking in a nationally representative sample. Am J Addict. 2016 Jun; 25(4):283-90. PMID: 27196699; PMCID: PMC4934605 [Available on 06/01/17].
    13. Foster KT, Li N, McClure EA, Sonne SC, Gray KM. Gender Differences in Internalizing Symptoms and Suicide Risk Among Men and Women Seeking Treatment for Cannabis Use Disorder from Late Adolescence to Middle Adulthood. J Subst Abuse Treat. 2016 07; 66:16-22. PMID: 27211992.
      View in: PubMed
    14. McClure E, Baker N, Carpenter MJ, Treiber FA, Gray K. Attitudes and interest in technology-based treatment and the remote monitoring of smoking among adolescents and emerging adults. J Smok Cessat. 2017 Jun; 12(2):88-98. PMID: 28580019.
      View in: PubMed
    15. Froeliger B, McConnell PA, Stankeviciute N, McClure EA, Kalivas PW, Gray KM. The effects of N-Acetylcysteine on frontostriatal resting-state functional connectivity, withdrawal symptoms and smoking abstinence: A double-blind, placebo-controlled fMRI pilot study. Drug Alcohol Depend. 2015 Nov 01; 156:234-242. PMID: 26454838; PMCID: PMC4633320 [Available on 11/01/16].
    16. Wray JM, Gray KM, McClure EA, Carpenter MJ, Tiffany ST, Saladin ME. Gender differences in responses to cues presented in the natural environment of cigarette smokers. Nicotine Tob Res. 2015 Apr; 17(4):438-42. PMID: 25762753; PMCID: PMC4432398.
    17. Saladin ME, McClure EA, Baker NL, Carpenter MJ, Ramakrishnan V, Hartwell KJ, Gray KM. Increasing progesterone levels are associated with smoking abstinence among free-cycling women smokers who receive brief pharmacotherapy. Nicotine Tob Res. 2015 Apr; 17(4):398-406. PMID: 25762749; PMCID: PMC4432400.
    18. Gray KM, McClure EA, Baker NL, Hartwell KJ, Carpenter MJ, Saladin ME. An exploratory short-term double-blind randomized trial of varenicline versus nicotine patch for smoking cessation in women. Addiction. 2015 Jun; 110(6):1027-34. PMID: 25727442; PMCID: PMC4430389.
    19. Mitchell SG, Schwartz RP, Alvanzo AA, Weisman MS, Kyle TL, Turrigiano EM, Gibson ML, Perez L, McClure EA, Clingerman S, Froias A, Shandera DR, Walker R, Babcock DL, Bailey GL, Miele GM, Kunkel LE, Norton M, Stitzer ML. The Use of Technology in Participant Tracking and Study Retention: Lessons Learned From a Clinical Trials Network Study. Subst Abus. 2015; 36(4):420-6. PMID: 25671593; PMCID: PMC4532645.
    20. McClure EA, Lydiard JB, Goddard SD, Gray KM. Objective and subjective memory ratings in cannabis-dependent adolescents. Am J Addict. 2015 Jan; 24(1):47-52. PMID: 25823635; PMCID: PMC4389632.
    21. McClure EA, Campbell AN, Pavlicova M, Hu M, Winhusen T, Vandrey RG, Ruglass LM, Covey LS, Stitzer ML, Kyle TL, Nunes EV. Cigarette Smoking During Substance Use Disorder Treatment: Secondary Outcomes from a National Drug Abuse Treatment Clinical Trials Network study. J Subst Abuse Treat. 2015 Jun; 53:39-46. PMID: 25595301.
      View in: PubMed
    22. McClure EA, Lydiard JB, Goddard SD, Gray KM. Objective and subjective memory ratings in cannabis-dependent adolescents. Am J Addict. 2014 Nov 6. PMID: 25376891.
      View in: PubMed
    23. Saladin ME, Wray JM, Carpenter MJ, McClure EA, LaRowe SD, Upadhyaya HP, Gray KM. Menstrual cycle phase effects in the gender dimorphic stress cue reactivity of smokers. Nicotine Tob Res. 2015 May; 17(5):607-11. PMID: 25324432; PMCID: PMC4402356.
    24. McClure EA, Sonne SC, Winhusen T, Carroll KM, Ghitza UE, McRae-Clark AL, Matthews AG, Sharma G, Van Veldhuisen P, Vandrey RG, Levin FR, Weiss RD, Lindblad R, Allen C, Mooney LJ, Haynes L, Brigham GS, Sparenborg S, Hasson AL, Gray KM. Achieving cannabis cessation -- evaluating N-acetylcysteine treatment (ACCENT): design and implementation of a multi-site, randomized controlled study in the National Institute on Drug Abuse Clinical Trials Network. Contemp Clin Trials. 2014 Nov; 39(2):211-23. PMID: 25179587; PMCID: PMC4252394.
    25. McClure EA, Baker NL, Gipson CD, Carpenter MJ, Roper AP, Froeliger BE, Kalivas PW, Gray KM. An open-label pilot trial of N-acetylcysteine and varenicline in adult cigarette smokers. Am J Drug Alcohol Abuse. 2015 Jan; 41(1):52-6. PMID: 25062287; PMCID: PMC4262740.
    26. Acquavita SP, McClure EA, Hargraves D, Stitzer M. Environmental tobacco smoke exposure among smokers and non-smokers receiving outpatient substance abuse treatment. Addict Behav. 2014 Dec; 39(12):1718-22. PMID: 25117848; PMCID: PMC4182101.
    27. Campbell AN, Nunes EV, Matthews AG, Stitzer M, Miele GM, Polsky D, Turrigiano E, Walters S, McClure EA, Kyle TL, Wahle A, Van Veldhuisen P, Goldman B, Babcock D, Stabile PQ, Winhusen T, Ghitza UE. Internet-delivered treatment for substance abuse: a multisite randomized controlled trial. Am J Psychiatry. 2014 Jun; 171(6):683-90. PMID: 24700332; PMCID: PMC4079279.
    28. McClure EA, Baker NL, Gray KM. Cigarette smoking during an N-acetylcysteine-assisted cannabis cessation trial in adolescents. Am J Drug Alcohol Abuse. 2014 Jul; 40(4):285-91. PMID: 24720376; PMCID: PMC4118750.
    29. Raiff BR, Karatas Ç, McClure EA, Pompili D, Walls TA. Laboratory Validation of Inertial Body Sensors to Detect Cigarette Smoking Arm Movements. Electronics (Basel). 2014 Feb 27; 3(1):87-110. PMID: 25553255.
      View in: PubMed
    30. McClure EA, Gipson CD, Malcolm RJ, Kalivas PW, Gray KM. Potential role of N-acetylcysteine in the management of substance use disorders. CNS Drugs. 2014 Feb; 28(2):95-106. PMID: 24442756; PMCID: PMC4009342.
    31. Carpenter MJ, Saladin ME, Larowe SD, McClure EA, Simonian S, Upadhyaya HP, Gray KM. Craving, cue reactivity, and stimulus control among early-stage young smokers: effects of smoking intensity and gender. Nicotine Tob Res. 2014 Feb; 16(2):208-15. PMID: 24042699; PMCID: PMC3880235.
    32. Campbell AN, Nunes EV, McClure EA, Hu MC, Turrigiano E, Goldman B, Stabile PQ. Characteristics of an outpatient treatment sample by primary substance of abuse. J Addict Med. 2013 Sep-Oct; 7(5):363-71. PMID: 24089040; PMCID: PMC3790139.
    33. McClure EA, Acquavita SP, Dunn KE, Stoller KB, Stitzer ML. Characterizing smoking, cessation services, and quit interest across outpatient substance abuse treatment modalities. J Subst Abuse Treat. 2014 Feb; 46(2):194-201. PMID: 23988192; PMCID: PMC3840070.
    34. McClure EA, Saladin ME, Baker NL, Carpenter MJ, Gray KM. Smoking topography and abstinence in adult female smokers. Addict Behav. 2013 Dec; 38(12):2833-6. PMID: 24018226; PMCID: PMC3805754.
    35. McClure EA, Gray KM. The Remote Monitoring of Smoking in Adolescents. Adolesc Psychiatry (Hilversum). 2013 Apr 01; 3(2):156-162. PMID: 24834379.
      View in: PubMed
    36. McClure EA, Acquavita SP, Harding E, Stitzer ML. Utilization of communication technology by patients enrolled in substance abuse treatment. Drug Alcohol Depend. 2013 Apr 01; 129(1-2):145-50. PMID: 23107600; PMCID: PMC3568219.
    37. McClure EA, Vandrey RG, Johnson MW, Stitzer ML. Effects of varenicline on abstinence and smoking reward following a programmed lapse. Nicotine Tob Res. 2013 Jan; 15(1):139-48. PMID: 22573730; PMCID: PMC3524062.
    38. Campbell AN, Nunes EV, Miele GM, Matthews A, Polsky D, Ghitza UE, Turrigiano E, Bailey GL, VanVeldhuisen P, Chapdelaine R, Froias A, Stitzer ML, Carroll KM, Winhusen T, Clingerman S, Perez L, McClure E, Goldman B, Crowell AR. Design and methodological considerations of an effectiveness trial of a computer-assisted intervention: an example from the NIDA Clinical Trials Network. Contemp Clin Trials. 2012 Mar; 33(2):386-95. PMID: 22085803; PMCID: PMC3268951.
    39. McClure EA, Stitzer ML, Vandrey R. Characterizing smoking topography of cannabis in heavy users. Psychopharmacology (Berl). 2012 Mar; 220(2):309-18. PMID: 21922170; PMCID: PMC3641906.
    40. McClure EA, Saulsgiver KA, Wynne CD. D-amphetamine, nicotine, and haloperidol produce similar disruptions in spatial and nonspatial temporal discrimination procedures. Behav Pharmacol. 2011 Apr; 22(2):101-12. PMID: 21301325; PMCID: PMC3366435.
    41. McClure EA, Saulsgiver KA, Wynne CD. Disruptive effects of stimulus intensity on two variations of a temporal discrimination procedure. J Exp Anal Behav. 2010 Jul; 94(1):57-68. PMID: 21279162; PMCID: PMC2893617.
    42. McClure EA, Saulsgiver KA, Wynne CD. ABA chronic dosing of D-amphetamine produces differential drug effects in two variants of a temporal discrimination procedure in pigeons. Behav Pharmacol. 2009 Dec; 20(8):705-19. PMID: 19901824.
      View in: PubMed
    43. McClure EA, Saulsgiver KA, Wynne CD. Effects of acute and chronic d-amphetamine on two variations of a temporal discrimination procedure. Behav Pharmacol. 2009 Oct; 20(7):668-72. PMID: 19738462.
      View in: PubMed
    44. McClure EA, Saulsgiver KA, Wynne CD. Manipulating pre-feed, density of reinforcement, and extinction produces disruption in the Location variation of a temporal discrimination task in pigeons. Behav Processes. 2009 Sep; 82(1):85-9. PMID: 19615617.
      View in: PubMed
    45. Saulsgiver KA, McClure EA, Wynne CD. Effects of amphetamine on differential reinforcement of low rates of responding. Behav Pharmacol. 2007 Mar; 18(2):119-33. PMID: 17351419.
      View in: PubMed
    46. Saulsgiver KA, McClure EA, Wynne CD. Effects of d-amphetamine on the behavior of pigeons exposed to the peak procedure. Behav Processes. 2006 Feb 28; 71(2-3):268-85. PMID: 16413140.
      View in: PubMed
    47. Jazbec S, McClure E, Hardin M, Pine DS, Ernst M. Cognitive control under contingencies in anxious and depressed adolescents: an antisaccade task. Biol Psychiatry. 2005 Oct 15; 58(8):632-9. PMID: 16018983.
      View in: PubMed
    48. McClure EA, Saulsgiver KA, Wynne CD. Effects of D-amphetamine on temporal discrimination in pigeons. Behav Pharmacol. 2005 Jul; 16(4):193-208. PMID: 15961959.
      View in: PubMed
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