Keywords
Last Name
Institution

Hugh L. Myrick

Title
InstitutionMedical University of South Carolina
DepartmentPsychiatry and Behavioral Sciences
AddressP.O. Box MSC 861
67 President St.
Phone843-789-7316
Fax843-792-7353
vCardDownload vCard

    Collapse Overview 
    Collapse overview
    Donald L. "Hugh" Myrick, MD, is an Associate Professor of Psychiatry in the Addiction Sciences Division at the Medical University of South Carolina. Dr. Myrick currently serves as the Medical Director of the Center for Drug and Alcohol Programs. In addition, he is the Associate Chief of Staff of the Mental Health Service Line at the Veterans Administration Medical Center in Charleston.

    Dr. Myrick’s research interests include the pharmacological treatment of addictive disorders. Specifically, he has completed trials using anticonvulsant agents in the treatment of alcohol withdrawal, alcoholism, and cocaine dependence. In addition, Dr. Myrick was awarded a K Award by NIAAA to use neuroimaging to determine the neuronal networks associated with craving.

    Dr. Myrick has written manuscripts and book chapters on the pharmacotherapy of substance abuse and dual diagnosis, and he speaks frequently on these topics at major association meetings. He is actively involved in intramural committees and mentoring activities as well professional organizations such as the American Psychiatric Association, the Research Society on Alcoholism, and the American Academy of Addiction Psychiatry.


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Schacht JP, Randall PK, Latham PK, Voronin KE, Book SW, Myrick H, Anton RF. Predictors of Naltrexone Response in a Randomized Trial: Reward-Related Brain Activation, OPRM1 Genotype, and Smoking Status. Neuropsychopharmacology. 2017 12; 42(13):2654. PMID: 29123234.
      View in: PubMed
    2. Trivedi MH, Greer TL, Rethorst CD, Carmody T, Grannemann BD, Walker R, Warden D, Shores-Wilson K, Stoutenberg M, Oden N, Silverstein M, Hodgkins C, Love L, Seamans C, Stotts A, Causey T, Szucs-Reed RP, Rinaldi P, Myrick H, Straus M, Liu D, Lindblad R, Church T, Blair SN, Nunes EV. Randomized Controlled Trial Comparing Exercise to Health Education for Stimulant Use Disorder: Results From the CTN-0037 STimulant Reduction Intervention Using Dosed Exercise (STRIDE) Study. J Clin Psychiatry. 2017 Sep/Oct; 78(8):1075-1082. PMID: 28199070.
      View in: PubMed
    3. Schacht JP, Randall PK, Latham PK, Voronin KE, Book SW, Myrick H, Anton RF. Predictors of Naltrexone Response in a Randomized Trial: Reward-Related Brain Activation, OPRM1 Genotype, and Smoking Status. Neuropsychopharmacology. 2017 Dec; 42(13):2640-2653. PMID: 28409564.
      View in: PubMed
    4. Malcolm R, Myrick H, Li X, Henderson S, Brady KT, George MS, See RE. Regional Brain Activity in Abstinent Methamphetamine Dependent Males Following Cue Exposure. J Drug Abuse. 2016; 2(1). PMID: 27314105.
      View in: PubMed
    5. De Santis ML, Myrick H, Lamis DA, Pelic CP, Rhue C, Rhue C, York J. Suicide-specific Safety in the Inpatient Psychiatric Unit. Issues Ment Health Nurs. 2015 Mar; 36(3):190-9. PMID: 25898018.
      View in: PubMed
    6. Harris AH, Bowe T, Del Re AC, Finlay AK, Oliva E, Myrick HL, Rubinsky AD. Extended release naltrexone for alcohol use disorders: quasi-experimental effects on mortality and subsequent detoxification episodes. Alcohol Clin Exp Res. 2015 Jan; 39(1):79-83. PMID: 25623408.
      View in: PubMed
    7. Zhang J, Sheerin C, Mandel H, Banducci AN, Myrick H, Acierno R, Amstadter AB, Wang Z. Variation in SLC1A1 is related to combat-related posttraumatic stress disorder. J Anxiety Disord. 2014 Dec; 28(8):902-7. PMID: 25445080.
      View in: PubMed
    8. Prisciandaro JJ, Joseph JE, Myrick H, McRae-Clark AL, Henderson S, Pfeifer J, Brady KT. The relationship between years of cocaine use and brain activation to cocaine and response inhibition cues. Addiction. 2014 Dec; 109(12):2062-70. PMID: 24938849.
      View in: PubMed
    9. Schacht JP, Anton RF, Randall PK, Li X, Henderson S, Myrick H. Varenicline effects on drinking, craving and neural reward processing among non-treatment-seeking alcohol-dependent individuals. Psychopharmacology (Berl). 2014 Sep; 231(18):3799-807. PMID: 24647921.
      View in: PubMed
    10. Prisciandaro JJ, Myrick H, Henderson S, McRae-Clark AL, Brady KT. Prospective associations between brain activation to cocaine and no-go cues and cocaine relapse. Drug Alcohol Depend. 2013 Jul 01; 131(1-2):44-9. PMID: 23683790.
      View in: PubMed
    11. Prisciandaro JJ, Myrick H, Henderson S, McRae-Clark AL, Santa Ana EJ, Saladin ME, Brady KT. Impact of DCS-facilitated cue exposure therapy on brain activation to cocaine cues in cocaine dependence. Drug Alcohol Depend. 2013 Sep 01; 132(1-2):195-201. PMID: 23497788.
      View in: PubMed
    12. Schacht JP, Anton RF, Randall PK, Li X, Henderson S, Myrick H. Effects of a GABA-ergic medication combination and initial alcohol withdrawal severity on cue-elicited brain activation among treatment-seeking alcoholics. Psychopharmacology (Berl). 2013 Jun; 227(4):627-37. PMID: 23389755.
      View in: PubMed
    13. Tuerk PW, Wangelin B, Rauch SA, Dismuke CE, Yoder M, Myrick H, Eftekhari A, Acierno R. Health service utilization before and after evidence-based treatment for PTSD. Psychol Serv. 2013 Nov; 10(4):401-9. PMID: 23148769.
      View in: PubMed
    14. Turner TH, Horner MD, Vankirk KK, Myrick H, Tuerk PW. A pilot trial of neuropsychological evaluations conducted via telemedicine in the Veterans Health Administration. Telemed J E Health. 2012 Nov; 18(9):662-7. PMID: 23050802.
      View in: PubMed
    15. Schacht JP, Anton RF, Voronin KE, Randall PK, Li X, Henderson S, Myrick H. Interacting effects of naltrexone and OPRM1 and DAT1 variation on the neural response to alcohol cues. Neuropsychopharmacology. 2013 Feb; 38(3):414-22. PMID: 23032071.
      View in: PubMed
    16. Verduin ML, LaRowe SD, Myrick H, Cannon-Bowers J, Bowers C. Computer simulation games as an adjunct for treatment in male veterans with alcohol use disorder. J Subst Abuse Treat. 2013 Mar; 44(3):316-22. PMID: 23009800.
      View in: PubMed
    17. Schacht JP, Anton RF, Myrick H. Functional neuroimaging studies of alcohol cue reactivity: a quantitative meta-analysis and systematic review. Addict Biol. 2013 Jan; 18(1):121-33. PMID: 22574861.
      View in: PubMed
    18. Anton RF, Voronin KK, Randall PK, Myrick H, Tiffany A. Naltrexone modification of drinking effects in a subacute treatment and bar-lab paradigm: influence of OPRM1 and dopamine transporter (SLC6A3) genes. Alcohol Clin Exp Res. 2012 Nov; 36(11):2000-7. PMID: 22551036.
      View in: PubMed
    19. Ditre JW, Oliver JA, Myrick H, Henderson S, Saladin ME, Drobes DJ. Effects of divalproex on smoking cue reactivity and cessation outcomes among smokers achieving initial abstinence. Exp Clin Psychopharmacol. 2012 Aug; 20(4):293-301. PMID: 22468897.
      View in: PubMed
    20. Prisciandaro JJ, McRae-Clark AL, Myrick H, Henderson S, Brady KT. Brain activation to cocaine cues and motivation/treatment status. Addict Biol. 2014 Mar; 19(2):240-9. PMID: 22458561.
      View in: PubMed
    21. Yoder M, Tuerk PW, Price M, Grubaugh AL, Strachan M, Myrick H, Acierno R. Prolonged exposure therapy for combat-related posttraumatic stress disorder: comparing outcomes for veterans of different wars. Psychol Serv. 2012 Feb; 9(1):16-25. PMID: 22449084.
      View in: PubMed
    22. Hartwell KJ, Johnson KA, Li X, Myrick H, LeMatty T, George MS, Brady KT. Neural correlates of craving and resisting craving for tobacco in nicotine dependent smokers. Addict Biol. 2011 Oct; 16(4):654-66. PMID: 21790899.
      View in: PubMed
    23. Schacht JP, Randall PK, Waid LR, Baros AM, Latham PK, Wright TM, Myrick H, Anton RF. Neurocognitive performance, alcohol withdrawal, and effects of a combination of flumazenil and gabapentin in alcohol dependence. Alcohol Clin Exp Res. 2011 Nov; 35(11):2030-8. PMID: 21631542.
      View in: PubMed
    24. Anton RF, Myrick H, Wright TM, Latham PK, Baros AM, Waid LR, Randall PK. Gabapentin combined with naltrexone for the treatment of alcohol dependence. Am J Psychiatry. 2011 Jul; 168(7):709-17. PMID: 21454917.
      View in: PubMed
    25. Schacht JP, Anton RF, Randall PK, Li X, Henderson S, Myrick H. Stability of fMRI striatal response to alcohol cues: a hierarchical linear modeling approach. Neuroimage. 2011 May 01; 56(1):61-8. PMID: 21316465.
      View in: PubMed
    26. Tuerk PW, Yoder M, Grubaugh A, Myrick H, Hamner M, Acierno R. Prolonged exposure therapy for combat-related posttraumatic stress disorder: an examination of treatment effectiveness for veterans of the wars in Afghanistan and Iraq. J Anxiety Disord. 2011 Apr; 25(3):397-403. PMID: 21131170.
      View in: PubMed
    27. Myrick H, Li X, Randall PK, Henderson S, Voronin K, Anton RF. The effect of aripiprazole on cue-induced brain activation and drinking parameters in alcoholics. J Clin Psychopharmacol. 2010 Aug; 30(4):365-72. PMID: 20571434.
      View in: PubMed
    28. Brady KT, Tuerk P, Back SE, Saladin ME, Waldrop AE, Myrick H. Combat posttraumatic stress disorder, substance use disorders, and traumatic brain injury. J Addict Med. 2009 Dec; 3(4):179-88. PMID: 21769015.
      View in: PubMed
    29. Anton RF, Myrick H, Baros AM, Latham PK, Randall PK, Wright TM, Stewart SH, Waid R, Malcolm R. Efficacy of a combination of flumazenil and gabapentin in the treatment of alcohol dependence: relationship to alcohol withdrawal symptoms. J Clin Psychopharmacol. 2009 Aug; 29(4):334-42. PMID: 19593171.
      View in: PubMed
    30. Myrick H, Malcolm R, Randall PK, Boyle E, Anton RF, Becker HC, Randall CL. A double-blind trial of gabapentin versus lorazepam in the treatment of alcohol withdrawal. Alcohol Clin Exp Res. 2009 Sep; 33(9):1582-8. PMID: 19485969.
      View in: PubMed
    31. Voronin K, Randall P, Myrick H, Anton R. Aripiprazole effects on alcohol consumption and subjective reports in a clinical laboratory paradigm--possible influence of self-control. Alcohol Clin Exp Res. 2008 Nov; 32(11):1954-61. PMID: 18782344.
      View in: PubMed
    32. Myrick H, Anton RF, Li X, Henderson S, Randall PK, Voronin K. Effect of naltrexone and ondansetron on alcohol cue-induced activation of the ventral striatum in alcohol-dependent people. Arch Gen Psychiatry. 2008 Apr; 65(4):466-75. PMID: 18391135.
      View in: PubMed
    33. LaRowe SD, Myrick H, Hedden S, Mardikian P, Saladin M, McRae A, Brady K, Kalivas PW, Malcolm R. Is cocaine desire reduced by N-acetylcysteine? Am J Psychiatry. 2007 Jul; 164(7):1115-7. PMID: 17606664.
      View in: PubMed
    34. Book SW, Myrick H, Malcolm R, Strain EC. Buprenorphine for postoperative pain following general surgery in a buprenorphine-maintained patient. Am J Psychiatry. 2007 Jun; 164(6):979. PMID: 17541066.
      View in: PubMed
    35. Wright TM, Myrick H, Malcolm R, Randall P, Boyle E, Henderson S, Anton R. Impact of lifetime alcohol quit attempts and medicated detoxifications on time to relapse during an index alcohol detoxification. J Addict Med. 2007 Mar; 1(1):15-20. PMID: 21768927.
      View in: PubMed
    36. Myrick H, Anton R, Voronin K, Wang W, Henderson S. A double-blind evaluation of gabapentin on alcohol effects and drinking in a clinical laboratory paradigm. Alcohol Clin Exp Res. 2007 Feb; 31(2):221-7. PMID: 17250613.
      View in: PubMed
    37. Wright TM, Myrick H. Acamprosate: a new tool in the battle against alcohol dependence. Neuropsychiatr Dis Treat. 2006 Dec; 2(4):445-53. PMID: 19412493.
      View in: PubMed
    38. Wright T, Myrick H, Henderson S, Peters H, Malcolm R. Risk factors for delirium tremens: a retrospective chart review. Am J Addict. 2006 May-Jun; 15(3):213-9. PMID: 16923667.
      View in: PubMed
    39. Becker HC, Myrick H, Veatch LM. Pregabalin is effective against behavioral and electrographic seizures during alcohol withdrawal. Alcohol Alcohol. 2006 Jul-Aug; 41(4):399-406. PMID: 16636010.
      View in: PubMed
    40. LaRowe SD, Mardikian P, Malcolm R, Myrick H, Kalivas P, McFarland K, Saladin M, McRae A, Brady K. Safety and tolerability of N-acetylcysteine in cocaine-dependent individuals. Am J Addict. 2006 Jan-Feb; 15(1):105-10. PMID: 16449100.
      View in: PubMed
    41. Myrick H, Taylor B, LaRowe S, Nguyen S, Boyle E, Cochran K, Malcolm R. A retrospective chart review comparing tiagabine and benzodiazepines for the treatment of alcohol withdrawal. J Psychoactive Drugs. 2005 Dec; 37(4):409-14. PMID: 16480168.
      View in: PubMed
    42. Turkcapar H, Kose S, Ince A, Myrick H. Beliefs as a predictor of relapse in alcohol-dependent Turkish men. J Stud Alcohol. 2005 Nov; 66(6):848-51. PMID: 16459947.
      View in: PubMed
    43. Anton RF, Moak DH, Latham P, Waid LR, Myrick H, Voronin K, Thevos A, Wang W, Woolson R. Naltrexone combined with either cognitive behavioral or motivational enhancement therapy for alcohol dependence. J Clin Psychopharmacol. 2005 Aug; 25(4):349-57. PMID: 16012278.
      View in: PubMed
    44. Bedwell JS, Horner MD, Yamanaka K, Li X, Myrick H, Nahas Z, George MS. Functional neuroanatomy of subcomponent cognitive processes involved in verbal working memory. Int J Neurosci. 2005 Jul; 115(7):1017-32. PMID: 16051547.
      View in: PubMed
    45. Lee YK, Park SW, Kim YK, Kim DJ, Jeong J, Myrick H, Kim YH. Effects of naltrexone on the ethanol-induced changes in the rat central dopaminergic system. Alcohol Alcohol. 2005 Jul-Aug; 40(4):297-301. PMID: 15897221.
      View in: PubMed
    46. Book SW, Myrick H. Novel anticonvulsants in the treatment of alcoholism. Expert Opin Investig Drugs. 2005 Apr; 14(4):371-6. PMID: 15882114.
      View in: PubMed
    47. Verduin ML, Carter RE, Brady KT, Myrick H, Timmerman MA. Health service use among persons with comorbid bipolar and substance use disorders. Psychiatr Serv. 2005 Apr; 56(4):475-80. PMID: 15812100.
      View in: PubMed
    48. Johnson BA, Swift RM, Addolorato G, Ciraulo DA, Myrick H. Safety and efficacy of GABAergic medications for treating alcoholism. Alcohol Clin Exp Res. 2005 Feb; 29(2):248-54. PMID: 15714047.
      View in: PubMed
    49. Frueh BC, Henderson S, Myrick H. Telehealth service delivery for persons with alcoholism. J Telemed Telecare. 2005; 11(7):372-5. PMID: 16238840.
      View in: PubMed
    50. Myrick H, Cluver J, Swavely S, Peters H. Diagnosis and treatment of co-occurring affective disorders and substance use disorders. Psychiatr Clin North Am. 2004 Dec; 27(4):649-59. PMID: 15550285.
      View in: PubMed
    51. Kim DJ, Yoon SJ, Choi B, Kim TS, Woo YS, Kim W, Myrick H, Peterson BS, Choi YB, Kim YK, Jeong J. Increased fasting plasma ghrelin levels during alcohol abstinence. Alcohol Alcohol. 2005 Jan-Feb; 40(1):76-9. PMID: 15520048.
      View in: PubMed
    52. Myrick H, Anton R. Recent advances in the pharmacotherapy of alcoholism. Curr Psychiatry Rep. 2004 Oct; 6(5):332-8. PMID: 15355755.
      View in: PubMed
    53. Mishory A, Molnar C, Koola J, Li X, Kozel FA, Myrick H, Stroud Z, Nahas Z, George MS. The maximum-likelihood strategy for determining transcranial magnetic stimulation motor threshold, using parameter estimation by sequential testing is faster than conventional methods with similar precision. J ECT. 2004 Sep; 20(3):160-5. PMID: 15343000.
      View in: PubMed
    54. Myrick H, Malcolm R, Taylor B, LaRowe S. Modafinil: preclinical, clinical, and post-marketing surveillance--a review of abuse liability issues. Ann Clin Psychiatry. 2004 Apr-Jun; 16(2):101-9. PMID: 15328903.
      View in: PubMed
    55. Myrick H, Anton RF, Li X, Henderson S, Drobes D, Voronin K, George MS. Differential brain activity in alcoholics and social drinkers to alcohol cues: relationship to craving. Neuropsychopharmacology. 2004 Feb; 29(2):393-402. PMID: 14679386.
      View in: PubMed
    56. Kim DJ, Jeong J, Kim KS, Chae JH, Jin SH, Ahn KJ, Myrick H, Yoon SJ, Kim HR, Kim SY. Complexity changes of the EEG induced by alcohol cue exposure in alcoholics and social drinkers. Alcohol Clin Exp Res. 2003 Dec; 27(12):1955-61. PMID: 14691383.
      View in: PubMed
    57. Lanford W, Myrick H, O'Bryan E, Gorman JM. A severe case of clonidine dependence and withdrawal. J Psychiatr Pract. 2003 Mar; 9(2):167-70. PMID: 15985928.
      View in: PubMed
    58. Myrick H, Brady KT. The use of divalproex in the treatment of addictive disorders. Psychopharmacol Bull. 2003; 37 Suppl 2:89-97. PMID: 15021864.
      View in: PubMed
    59. Brady KT, Myrick H, Henderson S, Coffey SF. The use of divalproex in alcohol relapse prevention: a pilot study. Drug Alcohol Depend. 2002 Aug 01; 67(3):323-30. PMID: 12127203.
      View in: PubMed
    60. Malcolm R, Myrick H, Roberts J, Wang W, Anton RF, Ballenger JC. The effects of carbamazepine and lorazepam on single versus multiple previous alcohol withdrawals in an outpatient randomized trial. J Gen Intern Med. 2002 May; 17(5):349-55. PMID: 12047731.
      View in: PubMed
    61. Malcolm R, Myrick H, Roberts J, Wang W, Anton RF. The differential effects of medication on mood, sleep disturbance, and work ability in outpatient alcohol detoxification. Am J Addict. 2002; 11(2):141-50. PMID: 12028744.
      View in: PubMed
    62. Myrick H, Henderson S, Dansky B, Pelic C, Brady KT. Clinical characteristics of under-reporters on urine drug screens in a cocaine treatment study. Am J Addict. 2002; 11(4):255-61. PMID: 12584868.
      View in: PubMed
    63. Myrick H, Henderson S, Anton RF. Utility of a new assay for carbohydrate-deficient transferrin (Biorad %CDT TIA) to monitor abstinence during a treatment outcome study. Alcohol Clin Exp Res. 2001 Sep; 25(9):1330-4. PMID: 11584153.
      View in: PubMed
    64. Myrick H, Henderson S, Brady KT, Malcom R, Measom M. Divalproex loading in the treatment of cocaine dependence. J Psychoactive Drugs. 2001 Jul-Sep; 33(3):283-7. PMID: 11718321.
      View in: PubMed
    65. Myrick H, Malcolm R, Henderson S, McCormick K. Gabapentin for misuse of homemade nicotine nasal spray. Am J Psychiatry. 2001 Mar; 158(3):498. PMID: 11230002.
      View in: PubMed
    66. Malcolm R, Myrick H, Brady KT, Ballenger JC. Update on anticonvulsants for the treatment of alcohol withdrawal. Am J Addict. 2001; 10(s1):s16-s23. PMID: 11268817.
      View in: PubMed
    67. Myrick H, Henderson S, Brady KT, Malcolm R. Gabapentin in the treatment of cocaine dependence: a case series. J Clin Psychiatry. 2001 Jan; 62(1):19-23. PMID: 11235923.
      View in: PubMed
    68. Myrick H, Brady KT, Malcolm R. New developments in the pharmacotherapy of alcohol dependence. Am J Addict. 2001; 10(s1):s3-s15. PMID: 11268820.
      View in: PubMed
    69. Malcolm R, Roberts JS, Wang W, Myrick H, Anton RF. Multiple previous detoxifications are associated with less responsive treatment and heavier drinking during an index outpatient detoxification. Alcohol. 2000 Nov; 22(3):159-64. PMID: 11163123.
      View in: PubMed
    70. Myrick H, Brady KT, Malcolm R. Divalproex in the treatment of alcohol withdrawal. Am J Drug Alcohol Abuse. 2000 Feb; 26(1):155-60. PMID: 10718170.
      View in: PubMed
    71. Myrick H, Anton RF. Clinical management of alcohol withdrawal. CNS Spectr. 2000 Feb; 5(2):22-32. PMID: 18296996.
      View in: PubMed
    72. Myrick H, Malcolm R, Brady KT. Gabapentin treatment of alcohol withdrawal. Am J Psychiatry. 1998 Nov; 155(11):1632. PMID: 9812141.
      View in: PubMed
    73. Myrick H, Markowitz JS, Henderson S. Priapism following trazodone overdose with cocaine use. Ann Clin Psychiatry. 1998 Jun; 10(2):81-3. PMID: 9669540.
      View in: PubMed
    74. Myrick H, Anton RF. Treatment of alcohol withdrawal. Alcohol Health Res World. 1998; 22(1):38-43. PMID: 15706731.
      View in: PubMed
    75. Brady KT, Myrick H, McElroy S. The relationship between substance use disorders, impulse control disorders, and pathological aggression. Am J Addict. 1998; 7(3):221-30. PMID: 9702290.
      View in: PubMed
    76. Markowitz JS, Finkenbine R, Myrick H, King L, Carson WH. Gabapentin abuse in a cocaine user: implications for treatment? J Clin Psychopharmacol. 1997 Oct; 17(5):423-4. PMID: 9315994.
      View in: PubMed
    77. Markowitz JS, Myrick H, Hiott W. Clonidine dependence. J Clin Psychopharmacol. 1997 Apr; 17(2):137-8. PMID: 10950490.
      View in: PubMed
    78. Myrick H, Brady KT. Social phobia in cocaine-dependent individuals. Am J Addict. 1997; 6(2):99-104. PMID: 9134071.
      View in: PubMed
    Myrick's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _