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Donald O. Castell

Title
InstitutionMedical University of South Carolina
DepartmentMedicine
AddressP.O. Box MSC 702
260
Thurmond Gazes - 30 Courtenay Drive
Phone843-876-4265
Fax843-876-7232
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Abdul-Hussein M, Khalaf M, Castell D. Throat Clearing, Frequently Reported, But is it GERD Related? J Clin Gastroenterol. 2018 Nov/Dec; 52(10):869-872. PMID: 29356788.
      View in: PubMed
    2. Wong U, Person EB, Castell DO, von Rosenvinge E, Raufman JP, Xie G. Improving High-resolution Impedance Manometry Using Novel Viscous and Super-viscous Substrates in the Supine and Upright Positions: A Pilot Study. J Neurogastroenterol Motil. 2018 Oct 01; 24(4):570-576. PMID: 30122029.
      View in: PubMed
    3. Rieder E, Riegler M, Simic AP, Skrobic OM, Bonavina L, Gurski R, Paireder M, Castell DO, Schoppmann SF. Alternative therapies for GERD: a way to personalized antireflux surgery. Ann N Y Acad Sci. 2018 Dec; 1434(1):360-369. PMID: 29774563.
      View in: PubMed
    4. Yadlapati R, Vaezi MF, Vela MF, Spechler SJ, Shaheen NJ, Richter J, Lacy BE, Katzka D, Katz PO, Kahrilas PJ, Gyawali PC, Gerson L, Fass R, Castell DO, Craft J, Hillman L, Pandolfino JE. Management options for patients with GERD and persistent symptoms on proton pump inhibitors: recommendations from an expert panel. Am J Gastroenterol. 2018 Jul; 113(7):980-986. PMID: 29686276.
      View in: PubMed
    5. Khalaf M, Chowdhary S, Elias PS, Castell D. Distal Esophageal Spasm: A Review. Am J Med. 2018 Sep; 131(9):1034-1040. PMID: 29605413.
      View in: PubMed
    6. Elias PS, Castell DO. Acid Control in Barrett's Esophagus: A Plea for Documentation. Am J Gastroenterol. 2018 02; 113(2):307. PMID: 29467537.
      View in: PubMed
    7. Abdul-Hussein M, Zhang C, Castell D. Symptom Index or Symptom Association Probability?: A Closer Look at Symptom Association in Suspected GERD Patients. J Clin Gastroenterol. 2018 Jan; 52(1):e7-e10. PMID: 27875359.
      View in: PubMed
    8. Abdul-Hussein M, Castell D. Symptom association latency during ambulatory reflux monitoring: a review of 1445 symptoms. Dis Esophagus. 2017 10 01; 30(10):1-6. PMID: 28859384.
      View in: PubMed
    9. Khalaf M, Brock AS, Castell D. Sporadic Fundic Gland Polyps and Gastric Acid Suppression Level. Am J Med Sci. 2017 12; 354(6):561-564. PMID: 29208252.
      View in: PubMed
    10. Johnson DA, Katz PO, Armstrong D, Cohen H, Delaney BC, Howden CW, Katelaris P, Tutuian RI, Castell DO. The Safety of Appropriate Use of Over-the-Counter Proton Pump Inhibitors: An Evidence-Based Review and Delphi Consensus. Drugs. 2017 Apr; 77(5):547-561. PMID: 28233274.
      View in: PubMed
    11. Hiestand M, Abdel Jalil A, Castell DO. Manometric Subtypes of Ineffective Esophageal Motility. Clin Transl Gastroenterol. 2017 Mar 09; 8(3):e78. PMID: 28277491.
      View in: PubMed
    12. Elias PS, Castell DO. The Role of Acid Suppression in Barrett's Esophagus. Am J Med. 2017 May; 130(5):525-529. PMID: 28159599.
      View in: PubMed
    13. Elias PS, Castell D. Pneumatic Dilation for Achalasia: Obliterate the Waist! Am J Gastroenterol. 2016 09; 111(9):1362. PMID: 27580786.
      View in: PubMed
    14. Yadlapati R, Keswani RN, Ciolino JD, Grande DP, Listernick ZI, Carlson DA, Castell DO, Dunbar KB, Gawron AJ, Gyawali CP, Katz PO, Katzka D, Lacy BE, Spechler SJ, Tatum R, Vela MF, Pandolfino JE. A System to Assess the Competency for Interpretation of Esophageal Manometry Identifies Variation in Learning Curves. Clin Gastroenterol Hepatol. 2017 Nov; 15(11):1708-1714.e3. PMID: 27473627.
      View in: PubMed
    15. Dunbar KB, Agoston AT, Odze RD, Huo X, Pham TH, Cipher DJ, Castell DO, Genta RM, Souza RF, Spechler SJ. Association of Acute Gastroesophageal Reflux Disease With Esophageal Histologic Changes. JAMA. 2016 May 17; 315(19):2104-12. PMID: 27187303.
      View in: PubMed
    16. Abdul-Hussein M, Freeman J, Castell DO. Cough and Throat Clearing: Atypical GERD Symptoms or Not GERD at All? J Clin Gastroenterol. 2016 May-Jun; 50(5):e50-4. PMID: 26196474.
      View in: PubMed
    17. Boland K, Abdul-Hussein M, Tutuian R, Castell DO. Characteristics of Consecutive Esophageal Motility Diagnoses After a Decade of Change. J Clin Gastroenterol. 2016 Apr; 50(4):301-6. PMID: 26422715.
      View in: PubMed
    18. O'Rourke AK, Lazar A, Murphy B, Castell DO, Martin-Harris B. Utility of Esophagram versus High-Resolution Manometry in the Detection of Esophageal Dysmotility. Otolaryngol Head Neck Surg. 2016 05; 154(5):888-91. PMID: 26908560.
      View in: PubMed
    19. Abdel Jalil AA, Castell DO. Ineffective Esophageal Motility (IEM): the Old-New Frontier in Esophagology. Curr Gastroenterol Rep. 2016 Jan; 18(1):1. PMID: 26685862.
      View in: PubMed
    20. Abdul-Hussein M, Freeman J, Castell D. Concomitant Administration of a Histamine2 Receptor Antagonist and Proton Pump Inhibitor Enhances Gastric Acid Suppression. Pharmacotherapy. 2015 Dec; 35(12):1124-9. PMID: 26621819.
      View in: PubMed
    21. Abdel Jalil A, Tutuian R, Castell DO. Achalasia: All Sticks in One Bundle! Clin Gastroenterol Hepatol. 2016 May; 14(5):e49. PMID: 26546754.
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    22. Castell DO, Tutuian R. Minor Motility Defects? Perhaps, but What About a True "Functional" Assessment? Clin Gastroenterol Hepatol. 2016 Mar; 14(3):481. PMID: 26453954.
      View in: PubMed
    23. Yadlapati R, Gawron AJ, Keswani RN, Bilimoria K, Castell DO, Dunbar KB, Gyawali CP, Jobe BA, Katz PO, Katzka DA, Lacy BE, Massey BT, Richter JE, Schnoll-Sussman F, Spechler SJ, Tatum R, Vela MF, Pandolfino JE. Identification of Quality Measures for Performance of and Interpretation of Data From Esophageal Manometry. Clin Gastroenterol Hepatol. 2016 Apr; 14(4):526-534.e1. PMID: 26499925.
      View in: PubMed
    24. Person E, Rife C, Freeman J, Clark A, Castell DO. A Novel Sleep Positioning Device Reduces Gastroesophageal Reflux: A Randomized Controlled Trial. J Clin Gastroenterol. 2015 Sep; 49(8):655-9. PMID: 26053170.
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    25. Carlson DA, Ravi K, Kahrilas PJ, Gyawali CP, Bredenoord AJ, Castell DO, Spechler SJ, Halland M, Kanuri N, Katzka DA, Leggett CL, Roman S, Saenz JB, Sayuk GS, Wong AC, Yadlapati R, Ciolino JD, Fox MR, Pandolfino JE. Diagnosis of Esophageal Motility Disorders: Esophageal Pressure Topography vs. Conventional Line Tracing. Am J Gastroenterol. 2015 Jul; 110(7):967-77; quiz 978. PMID: 26032151.
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    26. Abdel Jalil AA, Katzka DA, Castell DO. Approach to the patient with dysphagia. Am J Med. 2015 Oct; 128(10):1138.e17-23. PMID: 26007674.
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    27. Abdul-Hussein M, Castell DO. Monitoring for GE Reflux: Is Normal the New Normal? Dig Dis Sci. 2015 May; 60(5):1118-9. PMID: 25421560.
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    28. Clayton SB, Castell DO. Multiple good options are available for achalasia management. J Clin Gastroenterol. 2015 Mar; 49(3):194-8. PMID: 24618506.
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    29. Clayton SB, Rife C, Kalbfleisch JH, Castell DO. Viscous impedance is an important indicator of abnormal esophageal motility. Neurogastroenterol Motil. 2013 Jul; 25(7):563-e455. PMID: 23621545.
      View in: PubMed
    30. Castell DO. Motility: Achalasia subtyping directs therapy. Nat Rev Gastroenterol Hepatol. 2013 Apr; 10(4):202-3. PMID: 23478382.
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    31. Castell DO. Laryngopharyngeal reflux: to be or not to be? J Clin Gastroenterol. 2013 Mar; 47(3):193-4. PMID: 23391867.
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    32. Singh ER, Rife C, Clayton S, Naas P, Nietert P, Castell DO. Interobserver variability in esophageal body measurements with high-resolution manometry among new physician users. J Clin Gastroenterol. 2013 Feb; 47(2):e12-6. PMID: 22647828.
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    33. Pohl D, Arevalo F, Singh E, Freeman J, Tutuian R, Castell DO. Swallowing activity assessed by ambulatory impedance-pH monitoring predicts awake and asleep periods at night. Dig Dis Sci. 2013 Apr; 58(4):1049-53. PMID: 23179150.
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    34. Gullung JL, Hill EG, Castell DO, Martin-Harris B. Oropharyngeal and esophageal swallowing impairments: their association and the predictive value of the modified barium swallow impairment profile and combined multichannel intraluminal impedance-esophageal manometry. Ann Otol Rhinol Laryngol. 2012 Nov; 121(11):738-45. PMID: 23193907.
      View in: PubMed
    35. Heard R, Sharma N, Roberts J, Castell D, Pohl D. Wireless 'mini' multichannel intraluminal impedance-pH: what is the optimal design of a miniature wireless device? Dis Esophagus. 2014 Jul; 27(5):424-7. PMID: 22978791.
      View in: PubMed
    36. Heard R, Castell J, Castell DO, Pohl D. Characterization of patients with low baseline impedance on multichannel intraluminal impedance-pH reflux testing. J Clin Gastroenterol. 2012 Aug; 46(7):e55-7. PMID: 22476039.
      View in: PubMed
    37. Pohl D, Ciolino J, Roberts J, Savarino E, Freeman J, Nietert PJ, Tutuian R, Castell D. Functional aspects of distal oesophageal spasm: the role of onset velocity and contraction amplitude on bolus transit. Dig Liver Dis. 2012 Jul; 44(7):569-75. PMID: 22475443.
      View in: PubMed
    38. Hajar N, Castell DO, Ghomrawi H, Rackett R, Hila A. Impedance pH confirms the relationship between GERD and BMI. Dig Dis Sci. 2012 Jul; 57(7):1875-9. PMID: 22451118.
      View in: PubMed
    39. Castell DO. In the diagnosis of achalasia, "classic" might be "atypical". Clin Gastroenterol Hepatol. 2012 Jul; 10(7):821-2. PMID: 22361278.
      View in: PubMed
    40. Clayton SB, Rife CC, Singh ER, Kalbfleisch JH, Castell DO. Twice-daily proton pump inhibitor therapy does not decrease the frequency of reflux episodes during nocturnal recumbency in patients with refractory GERD: analysis of 200 patients using multichannel intraluminal impedance-pH testing. Dis Esophagus. 2012 Nov-Dec; 25(8):682-6. PMID: 22292567.
      View in: PubMed
    41. Roberts JR, Aravapalli A, Pohl D, Freeman J, Castell DO. Extraesophageal gastroesophageal reflux disease (GERD) symptoms are not more frequently associated with proximal esophageal reflux than typical GERD symptoms. Dis Esophagus. 2012 Nov-Dec; 25(8):678-81. PMID: 22243631.
      View in: PubMed
    42. Castell DO. The evolution of achalasia. Dig Dis Sci. 2012 Mar; 57(3):597-8. PMID: 22183822.
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    43. Katzka DA, Castell DO. Pneumatic dilation for achalasia--the way forward: authors' reply. Aliment Pharmacol Ther. 2011 Nov; 34(10):1246-7. PMID: 22004254.
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    44. Hila A, Chowdhury N, Hajar N, Castell DO. Swallow evaluation during multichannel intraluminal impedance and pH: an alternate method to assess esophageal transit. J Clin Gastroenterol. 2011 Nov-Dec; 45(10):862-6. PMID: 21857530.
      View in: PubMed
    45. Katzka DA, Castell DO. Review article: an analysis of the efficacy, perforation rates and methods used in pneumatic dilation for achalasia. Aliment Pharmacol Ther. 2011 Oct; 34(8):832-9. PMID: 21848630.
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    46. Castell DO. Academic mentoring: a 40-year adventure. Am J Gastroenterol. 2011 May; 106(5):820-2. PMID: 21502997.
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    47. Pearson JP, Parikh S, Orlando RC, Johnston N, Allen J, Tinling SP, Johnston N, Belafsky P, Arevalo LF, Sharma N, Castell DO, Fox M, Harding SM, Morice AH, Watson MG, Shields MD, Bateman N, McCallion WA, van Wijk MP, Wenzl TG, Karkos PD, Belafsky PC. Review article: reflux and its consequences--the laryngeal, pulmonary and oesophageal manifestations. Conference held in conjunction with the 9th International Symposium on Human Pepsin (ISHP) Kingston-upon-Hull, UK, 21-23 April 2010. Aliment Pharmacol Ther. 2011 Apr; 33 Suppl 1:1-71. PMID: 21366630.
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    48. Castell DO. High resolution esophageal manometry: devils and dinosaurs. Neurogastroenterol Motil. 2010 Jun; 22(6):600-1. PMID: 20377784.
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    49. Gerson LB, Huff FJ, Hila A, Hirota WK, Reilley S, Agrawal A, Lal R, Luo W, Castell D. Arbaclofen placarbil decreases postprandial reflux in patients with gastroesophageal reflux disease. Am J Gastroenterol. 2010 Jun; 105(6):1266-75. PMID: 20040914.
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    50. Blonski W, Vela MF, Castell DO. Comparison of reflux frequency during prolonged multichannel intraluminal impedance and pH monitoring on and off acid suppression therapy. J Clin Gastroenterol. 2009 Oct; 43(9):816-20. PMID: 19398927.
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    51. Kraichely RE, Farrugia G, Pittock SJ, Castell DO, Lennon VA. Neural autoantibody profile of primary achalasia. Dig Dis Sci. 2010 Feb; 55(2):307-11. PMID: 19499338.
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    52. Patterson N, Mainie I, Rafferty G, McGarvey L, Heaney L, Tutuian R, Castell D, Johnston BT. Nonacid reflux episodes reaching the pharynx are important factors associated with cough. J Clin Gastroenterol. 2009 May-Jun; 43(5):414-9. PMID: 19197196.
      View in: PubMed
    53. Blonski W, Vela MF, Freeman J, Sharma N, Castell DO. The effect of oral buspirone, pyridostigmine, and bethanechol on esophageal function evaluated with combined multichannel esophageal impedance-manometry in healthy volunteers. J Clin Gastroenterol. 2009 Mar; 43(3):253-60. PMID: 18987553.
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    54. Agrawal A, Roberts J, Sharma N, Tutuian R, Vela M, Castell DO. Symptoms with acid and nonacid reflux may be produced by different mechanisms. Dis Esophagus. 2009; 22(5):467-70. PMID: 19222535.
      View in: PubMed
    55. Butler SG, Stuart A, Castell D, Russell GB, Koch K, Kemp S. Effects of age, gender, bolus condition, viscosity, and volume on pharyngeal and upper esophageal sphincter pressure and temporal measurements during swallowing. J Speech Lang Hear Res. 2009 Feb; 52(1):240-53. PMID: 19064903.
      View in: PubMed
    56. Martin-Harris B, Brodsky MB, Michel Y, Castell DO, Schleicher M, Sandidge J, Maxwell R, Blair J. MBS measurement tool for swallow impairment--MBSImp: establishing a standard. Dysphagia. 2008 Dec; 23(4):392-405. PMID: 18855050.
      View in: PubMed
    57. Castell DO. High resolution manometry: a word of caution. Am J Gastroenterol. 2008 Oct; 103(10):2657-8. PMID: 18855865.
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    58. Pohl D, Ribolsi M, Savarino E, Frühauf H, Fried M, Castell DO, Tutuian R. Characteristics of the esophageal low-pressure zone in healthy volunteers and patients with esophageal symptoms: assessment by high-resolution manometry. Am J Gastroenterol. 2008 Oct; 103(10):2544-9. PMID: 18684179.
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    59. Sharma N, Castell DO. Further comment on proton pump inhibitor failures. Clin Gastroenterol Hepatol. 2009 Mar; 7(3):363. PMID: 19186217.
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    60. Blonski W, Hila A, Vela MF, Castell DO. An analysis of distal esophageal impedance in individuals with and without esophageal motility abnormalities. J Clin Gastroenterol. 2008 Aug; 42(7):776-81. PMID: 18360293.
      View in: PubMed
    61. Mainie I, Tutuian R, Castell DO. Addition of a H2 receptor antagonist to PPI improves acid control and decreases nocturnal acid breakthrough. J Clin Gastroenterol. 2008 Jul; 42(6):676-9. PMID: 18496394.
      View in: PubMed
    62. Koya DL, Agrawal A, Freeman JE, Castell DO. Impedance detected abnormal bolus transit in patients with normal esophageal manometry. Sensitive indicator of esophageal functional abnormality? Dis Esophagus. 2008; 21(6):563-9. PMID: 18564161.
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    63. Castell DO. Reflux testing in the 21st century: is there a role for pH only? Clin Gastroenterol Hepatol. 2008 Aug; 6(8):840-1. PMID: 18585975.
      View in: PubMed
    64. Castell DO. Emerging Technologies for Esophageal Manometry and pH Monitoring. Gastroenterol Hepatol (N Y). 2008 Jun; 4(6):404-6. PMID: 21904516.
      View in: PubMed
    65. Agrawal A, Castell DO. Clinical importance of impedance measurements. J Clin Gastroenterol. 2008 May-Jun; 42(5):579-83. PMID: 18364586.
      View in: PubMed
    66. Tutuian R, Vela MF, Hill EG, Mainie I, Agrawal A, Castell DO. Characteristics of symptomatic reflux episodes on Acid suppressive therapy. Am J Gastroenterol. 2008 May; 103(5):1090-6. PMID: 18445095.
      View in: PubMed
    67. Sharma N, Agrawal A, Freeman J, Vela MF, Castell D. An analysis of persistent symptoms in acid-suppressed patients undergoing impedance-pH monitoring. Clin Gastroenterol Hepatol. 2008 May; 6(5):521-4. PMID: 18356117.
      View in: PubMed
    68. Agrawal A, Castell DO. Is reflux dyspareunia a real entity? Nat Clin Pract Gastroenterol Hepatol. 2008 Apr; 5(4):192-3. PMID: 18317493.
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    69. Blonski W, Vela M, Safder A, Hila A, Castell DO. Revised criterion for diagnosis of ineffective esophageal motility is associated with more frequent dysphagia and greater bolus transit abnormalities. Am J Gastroenterol. 2008 Mar; 103(3):699-704. PMID: 18341490.
      View in: PubMed
    70. Agrawal A, Hila A, Tutuian R, Castell DO. Manometry and impedance characteristics of achalasia. Facts and myths. J Clin Gastroenterol. 2008 Mar; 42(3):266-70. PMID: 18223498.
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    71. Blonski W, Vela M, Hila A, Castell DO. Normal values for manometry performed with swallows of viscous test material. Scand J Gastroenterol. 2008; 43(2):155-60. PMID: 18224562.
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    72. Wilson JA, Mainie I, Tutuian R, Agrawal A, Castell DO. Multichannel intraluminal impedance and esophageal manometry data for unrestricted swallowing: establishing normal values. Dis Esophagus. 2008; 21(1):51-6. PMID: 18197939.
      View in: PubMed
    73. Castell D, Tutuian R. The changing paradigm of GERD. Curr Gastroenterol Rep. 2007 Dec; 9(6):441-2. PMID: 18377793.
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    74. Bernhard A, Pohl D, Fried M, Castell DO, Tutuian R. Influence of bolus consistency and position on esophageal high-resolution manometry findings. Dig Dis Sci. 2008 May; 53(5):1198-205. PMID: 17932767.
      View in: PubMed
    75. Blonski W, Hila A, Jain V, Freeman J, Vela M, Castell DO. Impedance manometry with viscous test solution increases detection of esophageal function defects compared to liquid swallows. Scand J Gastroenterol. 2007 Aug; 42(8):917-22. PMID: 17613920.
      View in: PubMed
    76. Mainie I, Tutuian R, Patel A, Castell DO. Regional esophageal dysfunction in scleroderma and achalasia using multichannel intraluminal impedance and manometry. Dig Dis Sci. 2008 Jan; 53(1):210-6. PMID: 17549634.
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    77. Sifrim D, Mittal R, Fass R, Smout A, Castell D, Tack J, Gregersen H. Review article: acidity and volume of the refluxate in the genesis of gastro-oesophageal reflux disease symptoms. Aliment Pharmacol Ther. 2007 May 01; 25(9):1003-17. PMID: 17439501.
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    78. Agrawal A, Hila A, Tutuian R, Mainie I, Castell DO. Bethanechol improves smooth muscle function in patients with severe ineffective esophageal motility. J Clin Gastroenterol. 2007 Apr; 41(4):366-70. PMID: 17413603.
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    79. Hila A, Agrawal A, Castell DO. Combined multichannel intraluminal impedance and pH esophageal testing compared to pH alone for diagnosing both acid and weakly acidic gastroesophageal reflux. Clin Gastroenterol Hepatol. 2007 Feb; 5(2):172-7. PMID: 17296528.
      View in: PubMed
    80. Mainie I, Tutuian R, Agrawal A, Adams D, Castell DO. Combined multichannel intraluminal impedance-pH monitoring to select patients with persistent gastro-oesophageal reflux for laparoscopic Nissen fundoplication. Br J Surg. 2006 Dec; 93(12):1483-7. PMID: 17051602.
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    81. Bredenoord AJ, Tutuian R, Smout AJ, Castell DO. Technology review: Esophageal impedance monitoring. Am J Gastroenterol. 2007 Jan; 102(1):187-94. PMID: 17100961.
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    82. Tutuian R, Castell DO, Katz PO. Pneumatic dilatations for achalasia: a safe and effective choice for most patients. Am J Gastroenterol. 2006 Oct; 101(10):2441-2. PMID: 17032214.
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    83. Tutuian R, Castell DO. Review article: complete gastro-oesophageal reflux monitoring - combined pH and impedance. Aliment Pharmacol Ther. 2006 Sep; 24 Suppl 2:27-37. PMID: 16939430.
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    84. Mainie I, Tutuian R, Castell DO. The limitations of pH monitoring for detecting gastroesophageal reflux. Clin Gastroenterol Hepatol. 2006 Sep; 4(9):1184; author reply 1185. PMID: 16962511.
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    85. Mainie I, Tutuian R, Castell DO. Comparison between the combined analysis and the DeMeester Score to predict response to PPI therapy. J Clin Gastroenterol. 2006 Aug; 40(7):602-5. PMID: 16917401.
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    86. Hila A, Bouali H, Xue S, Knuff D, Castell DO. Postprandial stomach contents have multiple acid layers. J Clin Gastroenterol. 2006 Aug; 40(7):612-7. PMID: 16917403.
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    87. Tutuian R, Mainie I, Agrawal A, Adams D, Castell DO. Nonacid reflux in patients with chronic cough on acid-suppressive therapy. Chest. 2006 Aug; 130(2):386-91. PMID: 16899836.
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    88. Tutuian R, Castell DO. Esophageal motility disorders (distal esophageal spasm, nutcracker esophagus, and hypertensive lower esophageal sphincter): modern management. Curr Treat Options Gastroenterol. 2006 Jul; 9(4):283-94. PMID: 16836947.
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    89. Agrawal A, Hila A, Tutuian R, Mainie I, Castell DO. Clinical relevance of the nutcracker esophagus: suggested revision of criteria for diagnosis. J Clin Gastroenterol. 2006 Jul; 40(6):504-9. PMID: 16825932.
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    90. Tutuian R, Mainie I, Allan R, Hargreaves K, Agrawal A, Freeman J, Gale J, Castell DO. Effects of a 5-HT(4) receptor agonist on oesophageal function and gastro-oesophageal reflux: studies using combined impedance-manometry and combined impedance-pH. Aliment Pharmacol Ther. 2006 Jul 01; 24(1):155-62. PMID: 16803614.
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    91. Tutuian R, Castell DO. Review article: oesophageal spasm - diagnosis and management. Aliment Pharmacol Ther. 2006 May 15; 23(10):1393-402. PMID: 16669954.
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    92. Miner PB, Tutuian R, Castell DO, Liu S, Sostek MB. Intragastric acidity after switching from 5-day treatment with intravenous pantoprazole 40 mg/d to 5-day treatment with oral esomeprazole 40 mg/d or pantoprazole 40 mg/d: an open-label crossover study in healthy adult volunteers. Clin Ther. 2006 May; 28(5):725-33. PMID: 16861094.
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    93. Agrawal A, Castell D. GERD is chronic but not progressive. J Clin Gastroenterol. 2006 May-Jun; 40(5):374-5. PMID: 16721215.
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    94. Tutuian R, Castell DO. Clinical Applications of Esophageal Multichannel Intraluminal Impedance Testing. Gastroenterol Hepatol (N Y). 2006 Apr; 2(4):250-258. PMID: 28286455.
      View in: PubMed
    95. Mainie I, Tutuian R, Shay S, Vela M, Zhang X, Sifrim D, Castell DO. Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy: a multicentre study using combined ambulatory impedance-pH monitoring. Gut. 2006 Oct; 55(10):1398-402. PMID: 16556669.
      View in: PubMed
    96. Tutuian R, Mainie I, Agrawal A, Gideon RM, Katz PO, Castell DO. Symptom and function heterogenicity among patients with distal esophageal spasm: studies using combined impedance-manometry. Am J Gastroenterol. 2006 Mar; 101(3):464-9. PMID: 16542281.
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    97. Tutuian R, Castell DO. Pressure details from the weight-challenged gastroesophageal junction: more than the usual suspects. Gastroenterology. 2006 Mar; 130(3):988-9. PMID: 16530533.
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    98. Tutuian R, Castell DO. Esophageal pH monitoring: wireless does not mean worry less. J Clin Gastroenterol. 2006 Feb; 40(2):91-2. PMID: 16394866.
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    99. Agrawal A, Hila A, Tutuian R, Mainie I, Adams D, Castell DO. Laparoscopic Nissen fundoplication after biopolymer injection: a case report. Gastrointest Endosc. 2006 Mar; 63(3):520-2. PMID: 16500415.
      View in: PubMed
    100. Mainie I, Castell DO. Do we need to rethink fundoplication for patients who have failed proton-pump-inhibitor therapy? Nat Clin Pract Gastroenterol Hepatol. 2006 Jan; 3(1):2-3. PMID: 16397586.
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    101. Tutuian R, Pohl D, Castell DO, Fried M. Clearance mechanisms of the aperistaltic oesophagus: the "pump gun" hypothesis. Gut. 2006 Apr; 55(4):584-5. PMID: 16354796.
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    102. Castell D. Review of immediate-release omeprazole for the treatment of gastric acid-related disorders. Expert Opin Pharmacother. 2005 Nov; 6(14):2501-10. PMID: 16259581.
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    103. Agrawal A, Tutuian R, Hila A, Castell DO. Successful use of phosphodiesterase type 5 inhibitors to control symptomatic esophageal hypercontractility: a case report. Dig Dis Sci. 2005 Nov; 50(11):2059-62. PMID: 16240215.
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    104. Agrawal A, Tutuian R, Hila A, Freeman J, Castell DO. Ingestion of acidic foods mimics gastroesophageal reflux during pH monitoring. Dig Dis Sci. 2005 Oct; 50(10):1916-20. PMID: 16187197.
      View in: PubMed
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    126. Tutuian R, Castell DO. Diagnosis of laryngopharyngeal reflux. Curr Opin Otolaryngol Head Neck Surg. 2004 Jun; 12(3):174-9. PMID: 15167025.
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    140. Shaker R, Castell DO, Schoenfeld PS, Spechler SJ. Nighttime heartburn is an under-appreciated clinical problem that impacts sleep and daytime function: the results of a Gallup survey conducted on behalf of the American Gastroenterological Association. Am J Gastroenterol. 2003 Jul; 98(7):1487-93. PMID: 12873567.
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    142. Tutuian R, Castell DO. Barrett's esophagus prevalence and epidemiology. Gastrointest Endosc Clin N Am. 2003 Apr; 13(2):227-32. PMID: 12916656.
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    143. Castell DO. Nocturnal acid breakthrough in perspective: let's not throw out the baby with the bath water. Am J Gastroenterol. 2003 Mar; 98(3):517-8. PMID: 12650778.
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    145. Maldonado A, Diederich L, Castell DO, Gideon RM, Katz PO. Laryngopharyngeal reflux identified using a new catheter design: defining normal values and excluding artifacts. Laryngoscope. 2003 Feb; 113(2):349-55. PMID: 12567094.
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    146. Hila A, Castell DO. Gastroesophageal Reflux Disease. Curr Treat Options Gastroenterol. 2003 Feb; 6(1):41-48. PMID: 12521571.
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    148. van Herwaarden MA, Katz PO, Gideon RM, Barrett J, Castell JA, Achem S, Castell DO. Are manometric parameters of the upper esophageal sphincter and pharynx affected by age and gender? Dysphagia. 2003; 18(3):211-7. PMID: 14506987.
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    149. Brito EM, Camacho-Lobato L, Paoletti V, Gideon M, Katz PO, Castell DO. Effect of different swallow time intervals on the nutcracker esophagus. Am J Gastroenterol. 2003 Jan; 98(1):40-5. PMID: 12526934.
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    150. Castell DO. Does acid suppression alter progression in Barrett's esophagus? Am J Gastroenterol. 2003 Jan; 98(1):213-4; author reply 214. PMID: 12526966.
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    152. Jalil S, Castell DO. Schatzki's ring: a benign cause of dysphagia in adults. J Clin Gastroenterol. 2002 Oct; 35(4):295-8. PMID: 12352291.
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    155. Castell DO, Kahrilas PJ, Richter JE, Vakil NB, Johnson DA, Zuckerman S, Skammer W, Levine JG. Esomeprazole (40 mg) compared with lansoprazole (30 mg) in the treatment of erosive esophagitis. Am J Gastroenterol. 2002 Mar; 97(3):575-83. PMID: 11922549.
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    156. Triadafilopoulos G, DiBaise JK, Nostrant TT, Stollman NH, Anderson PK, Wolfe MM, Rothstein RI, Wo JM, Corley DA, Patti MG, Antignano LV, Goff JS, Edmundowicz SA, Castell DO, Rabine JC, Kim MS, Utley DS. The Stretta procedure for the treatment of GERD: 6 and 12 month follow-up of the U.S. open label trial. Gastrointest Endosc. 2002 Feb; 55(2):149-56. PMID: 11818914.
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    157. Castell DO. Noncardiac chest pain: on the horns of a dilemma. J Clin Gastroenterol. 2002 Jan; 34(1):3. PMID: 11743238.
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    164. Spechler SJ, Castell DO. Classification of oesophageal motility abnormalities. Gut. 2001 Jul; 49(1):145-51. PMID: 11413123.
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    169. Triadafilopoulos G, Dibaise JK, Nostrant TT, Stollman NH, Anderson PK, Edmundowicz SA, Castell DO, Kim MS, Rabine JC, Utley DS. Radiofrequency energy delivery to the gastroesophageal junction for the treatment of GERD. Gastrointest Endosc. 2001 Apr; 53(4):407-15. PMID: 11275878.
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    174. Arora AS, Castell DO. Medical therapy for gastroesophageal reflux disease. Mayo Clin Proc. 2001 Jan; 76(1):102-6. PMID: 11155401.
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    175. Kahrilas PJ, Quigley EM, Castell DO, Spechler SJ. The effects of tegaserod (HTF 919) on oesophageal acid exposure in gastro-oesophageal reflux disease. Aliment Pharmacol Ther. 2000 Nov; 14(11):1503-9. PMID: 11069322.
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    178. van Herwaarden MA, Katzka DA, Smout AJ, Samsom M, Gideon M, Castell DO. Effect of different recumbent positions on postprandial gastroesophageal reflux in normal subjects. Am J Gastroenterol. 2000 Oct; 95(10):2731-6. PMID: 11051341.
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    179. Castell DO. Total acid suppression and its effect on Barrett's esophagus. Am J Manag Care. 2000 Oct; 6(16 Suppl):S895-8. PMID: 11184662.
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    180. Beedassy A, Katz PO, Gruber A, Peghini PL, Castell DO. Prior sensitization of esophageal mucosa by acid reflux predisposes to reflux-induced chest pain. J Clin Gastroenterol. 2000 Sep; 31(2):121-4. PMID: 10993426.
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    184. Castell DO. Nasogastric tubes permit reflux and aspiration: is there any evidence? Ann Intern Med. 2000 Apr 04; 132(7):594-5. PMID: 10744605.
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    185. Meyer GW, Gernhardt DC, Castell DO. Peristaltic pressure profiles of the human esophagus. J Clin Gastroenterol. 2000 Apr; 30(3):270-3. PMID: 10777186.
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    192. Fouad YM, Katz PO, Castell DO. Oesophageal motility defects associated with nocturnal gastro-oesophageal reflux on proton pump inhibitors. Aliment Pharmacol Ther. 1999 Nov; 13(11):1467-71. PMID: 10571603.
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    193. Khan AA, Shah SW, Alam A, Butt AK, Shafqat F, Castell DO. Massively dilated esophagus in achalasia: response to pneumatic balloon dilation. Am J Gastroenterol. 1999 Sep; 94(9):2363-6. PMID: 10483992.
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    194. Gideon RM, Castell DO, Yarze J. Prospective randomized comparison of pneumatic dilatation technique in patients with idiopathic achalasia. Dig Dis Sci. 1999 Sep; 44(9):1853-7. PMID: 10505725.
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    195. Khoury RM, Katz PO, Castell DO. Post-prandial ranitidine is superior to post-prandial omeprazole in control of gastric acidity in healthy volunteers. Aliment Pharmacol Ther. 1999 Sep; 13(9):1211-4. PMID: 10468703.
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    196. Khoury RM, Camacho-Lobato L, Katz PO, Mohiuddin MA, Castell DO. Influence of spontaneous sleep positions on nighttime recumbent reflux in patients with gastroesophageal reflux disease. Am J Gastroenterol. 1999 Aug; 94(8):2069-73. PMID: 10445529.
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    197. Mohiuddin MA, Pursnani KG, Katzka DA, Castell JA, Castell DO. Effect of cyclic hormonal changes during normal menstrual cycle on esophageal motility. Dig Dis Sci. 1999 Jul; 44(7):1368-75. PMID: 10489922.
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    198. Tytgat G, Castell D. The hidden challenge of dyspepsia and heartburn: Is the world united? Summary and closing comments: key agenda for the coming years. Eur J Gastroenterol Hepatol. 1999 Jun; 11 Suppl 1:S43. PMID: 10443912.
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    199. Castell D. My approach to the difficult GERD patient. Eur J Gastroenterol Hepatol. 1999 Jun; 11 Suppl 1:S17-23. PMID: 10443908.
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    201. DeVault KR, Castell DO. Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease. The Practice Parameters Committee of the American College of Gastroenterology. Am J Gastroenterol. 1999 Jun; 94(6):1434-42. PMID: 10364004.
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    202. Castell D, Silvers D, Littlejohn T, Orr W, Napolitano J, Oleka N, Jokubaitis L. Cisapride 20 mg b.d. for preventing symptoms of GERD induced by a provocative meal. The CIS-USA-89 Study Group. Aliment Pharmacol Ther. 1999 Jun; 13(6):787-94. PMID: 10383509.
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    203. Khoury RM, Katz PO, Hammod R, Castell DO. Bedtime ranitidine does not eliminate the need for a second daily dose of omeprazole to suppress nocturnal gastric pH. Aliment Pharmacol Ther. 1999 May; 13(5):675-8. PMID: 10233192.
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    204. Koerselman J, Pursnani KG, Peghini P, Mohiuddin MA, Katzka D, Akkermans LM, Castell DO. Different effects of an oral anticholinergic drug on gastroesophageal reflux in upright and supine position in normal, ambulant subjects: a pilot study. Am J Gastroenterol. 1999 Apr; 94(4):925-30. PMID: 10201458.
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    205. Katzka DA, Castell DO. Use of botulinum toxin as a diagnostic/therapeutic trial to help clarify an indication for definitive therapy in patients with achalasia. Am J Gastroenterol. 1999 Mar; 94(3):637-42. PMID: 10086644.
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    206. Castell DO, Katzka DA. Barrett's esophagus: continuing questions and controversy. Gastrointest Endosc. 1999 Mar; 49(3 Pt 2):S5-8. PMID: 10049439.
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    207. Johnston BT, Shils J, Leite LP, Castell DO. Effects of octreotide on esophageal visceral perception and cerebral evoked potentials induced by balloon distension. Am J Gastroenterol. 1999 Jan; 94(1):65-70. PMID: 9934732.
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    208. Galan AR, Katzka DA, Castell DO. Acid secretion from an esophageal inlet patch demonstrated by ambulatory pH monitoring. Gastroenterology. 1998 Dec; 115(6):1574-6. PMID: 9834287.
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    209. Hatlebakk JG, Katz PO, Kuo B, Castell DO. Nocturnal gastric acidity and acid breakthrough on different regimens of omeprazole 40 mg daily. Aliment Pharmacol Ther. 1998 Dec; 12(12):1235-40. PMID: 9882032.
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    210. Peghini PL, Katz PO, Castell DO. Ranitidine controls nocturnal gastric acid breakthrough on omeprazole: a controlled study in normal subjects. Gastroenterology. 1998 Dec; 115(6):1335-9. PMID: 9834259.
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    211. Katz PO, Anderson C, Khoury R, Castell DO. Gastro-oesophageal reflux associated with nocturnal gastric acid breakthrough on proton pump inhibitors. Aliment Pharmacol Ther. 1998 Dec; 12(12):1231-4. PMID: 9882031.
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    212. Hatlebakk JG, Castell JA, Spiegel J, Paoletti V, Katz PO, Castell DO. Dilatation therapy for dysphagia in patients with upper esophageal sphincter dysfunction--manometric and symptomatic response. Dis Esophagus. 1998 Oct; 11(4):254-9. PMID: 10071809.
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    213. Katz PO, Gilbert J, Castell DO. Pneumatic dilatation is effective long-term treatment for achalasia. Dig Dis Sci. 1998 Sep; 43(9):1973-7. PMID: 9753261.
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    214. Katzka DA, Gideon RM, Castell DO. Normal patterns of acid exposure at the gastric cardia: a functional midpoint between the esophagus and stomach. Am J Gastroenterol. 1998 Aug; 93(8):1236-42. PMID: 9707044.
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    215. Khan AA, Shah SW, Alam A, Butt AK, Shafqat F, Castell DO. Pneumatic balloon dilation in achalasia: a prospective comparison of balloon distention time. Am J Gastroenterol. 1998 Jul; 93(7):1064-7. PMID: 9672331.
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    216. Olsson R, Castell J, Ekberg O, Castell DO. Videomanometry of the pharynx in dysphagic patients with laryngeal barium penetration during swallowing. Acta Radiol. 1998 Jul; 39(4):405-9. PMID: 9685828.
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    217. Corso MJ, Pursnani KG, Mohiuddin MA, Gideon RM, Castell JA, Katzka DA, Katz PO, Castell DO. Globus sensation is associated with hypertensive upper esophageal sphincter but not with gastroesophageal reflux. Dig Dis Sci. 1998 Jul; 43(7):1513-7. PMID: 9690388.
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    218. Katzka DA, Castell DO. Esophageal manometry and modern medicine. Dig Dis. 1998 Jul-Aug; 16(4):189-91. PMID: 9732177.
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    219. Castell DO, Katz PO. The acid suppression test for unexplained chest pain. Gastroenterology. 1998 Jul; 115(1):222-4. PMID: 9649480.
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    220. Peghini PL, Katz PO, Castell DO. Imipramine decreases oesophageal pain perception in human male volunteers. Gut. 1998 Jun; 42(6):807-13. PMID: 9691919.
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    221. Peghini PL, Katz PO, Bracy NA, Castell DO. Nocturnal recovery of gastric acid secretion with twice-daily dosing of proton pump inhibitors. Am J Gastroenterol. 1998 May; 93(5):763-7. PMID: 9625124.
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    222. Pursnani KG, Mohiuddin MA, Geisinger KR, Weinbaum G, Katzka DA, Castell DO. Experimental study of acid burden and acute oesophagitis. Br J Surg. 1998 May; 85(5):677-80. PMID: 9635821.
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    223. Ter RB, Johnston BT, Castell DO. Influence of age and gender on gastroesophageal reflux in symptomatic patients. Dis Esophagus. 1998 Apr; 11(2):106-8. PMID: 9779366.
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    224. Castell DO, Sigmund C, Patterson D, Lambert R, Hasner D, Clyde C, Zeldis JB. Cisapride 20 mg b.i.d. provides symptomatic relief of heartburn and related symptoms of chronic mild to moderate gastroesophageal reflux disease. CIS-USA-52 Investigator Group. Am J Gastroenterol. 1998 Apr; 93(4):547-52. PMID: 9576446.
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    225. Katz PO, Castell DO. Gastroesophageal reflux disease during pregnancy. Gastroenterol Clin North Am. 1998 Mar; 27(1):153-67. PMID: 9546088.
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    226. Peghini PL, Pursnani KG, Gideon MR, Castell JA, Nierman J, Castell DO. Proximal and distal esophageal contractions have similar manometric features. Am J Physiol. 1998 02; 274(2):G325-30. PMID: 9486186.
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    227. Castell DO, Katz PO. Acid control and regression of Barrett's esophagus: is the glass half full or half empty? Am J Gastroenterol. 1997 Dec; 92(12):2329-30. PMID: 9399786.
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    228. Achem SR, Kolts BE, MacMath T, Richter J, Mohr D, Burton L, Castell DO. Effects of omeprazole versus placebo in treatment of noncardiac chest pain and gastroesophageal reflux. Dig Dis Sci. 1997 Oct; 42(10):2138-45. PMID: 9365149.
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    229. Leite LP, Johnston BT, Barrett J, Castell JA, Castell DO. Ineffective esophageal motility (IEM): the primary finding in patients with nonspecific esophageal motility disorder. Dig Dis Sci. 1997 Sep; 42(9):1859-65. PMID: 9331148.
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    230. Pursnani KG, Oeffner C, Gideon RM, Castell DO. Comparison of lower oesophageal sphincter pressure measurement using circumferential vs unidirectional transducers. Neurogastroenterol Motil. 1997 Sep; 9(3):177-80. PMID: 9347473.
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    231. Ter RB, Castell DO. Gastroesophageal reflux disease in patients with columnar-lined esophagus. Gastroenterol Clin North Am. 1997 Sep; 26(3):549-63. PMID: 9309404.
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    232. Pursnani KG, Sataloff DM, Zayas F, Castell DO. Evaluation of the antireflux mechanism following laparoscopic fundoplication. Br J Surg. 1997 Aug; 84(8):1157-61. PMID: 9278667.
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    233. Sataloff DM, Pursnani K, Hoyo S, Zayas F, Lieber C, Castell DO. An objective assessment of laparoscopic antireflux surgery. Am J Surg. 1997 Jul; 174(1):63-7. PMID: 9240955.
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    234. Ter RB, Johnston BT, Castell DO. Exclusion of the meal period improves the clinical reliability of esophageal pH monitoring. J Clin Gastroenterol. 1997 Jul; 25(1):314-6. PMID: 9412910.
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    235. Peghini PL, Castell DO. Does sensitization of esophageal mucosal receptors occur during provocative testing? Am J Gastroenterol. 1997 Jun; 92(6):919-20. PMID: 9177501.
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    236. Olsson R, Castell J, Johnston B, Ekberg O, Castell DO. Combined videomanometric identification of abnormalities related to pharyngeal retention. Acad Radiol. 1997 May; 4(5):349-54. PMID: 9156231.
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    237. Katz PO, Katzka DA, Castell DO. Chest pain and the esophagus. Ann Intern Med. 1997 May 01; 126(9):740-1. PMID: 9139566.
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    238. Siddiqui MA, Castell DO. Gastrointestinal disorders in the elderly. Compr Ther. 1997 May; 23(5):349-59. PMID: 9195126.
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    239. Johnston BT, Castell JA, Stumacher S, Colcher A, Gideon RM, Li Q, Castell DO. Comparison of swallowing function in Parkinson's disease and progressive supranuclear palsy. Mov Disord. 1997 May; 12(3):322-7. PMID: 9159726.
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    240. Castell DO, Katz PO. Lower esophageal sphincter or upper gastric sphincter? Dis Esophagus. 1997 Apr; 10(2):119-20. PMID: 9179482.
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    241. Mohiuddin MA, Pursnani KG, Katzka DA, Gideon RM, Castell JA, Castell DO. Effective gastric acid suppression after oral administration of enteric-coated omeprazole granules. Dig Dis Sci. 1997 Apr; 42(4):715-9. PMID: 9125637.
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    242. Katz PO, Codario R, Castell DO. Approach to the patient with unexplained chest pain. Compr Ther. 1997 Apr; 23(4):249-53. PMID: 9167916.
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    243. Katz PO, Castell DO. Current medical treatment and indications for surgical referral for gastroesophageal reflux disease (GERD). Semin Thorac Cardiovasc Surg. 1997 Apr; 9(2):169-72. PMID: 9253080.
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    244. Sontag SJ, Kogut DG, Fleischmann R, Campbell DR, Richter J, Robinson M, McFarland M, Sabesin S, Lehman GA, Castell D. Lansoprazole heals erosive reflux esophagitis resistant to histamine H2-receptor antagonist therapy. Am J Gastroenterol. 1997 Mar; 92(3):429-37. PMID: 9068463.
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    245. Lasch H, Castell DO, Castell JA. Evidence for diminished visceral pain with aging: studies using graded intraesophageal balloon distension. Am J Physiol. 1997 Jan; 272(1 Pt 1):G1-3. PMID: 9038868.
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    246. Castell JA, Castell DO. Recent developments in the manometric assessment of upper esophageal sphincter function and dysfunction. Dig Dis. 1997; 15 Suppl 1:28-39. PMID: 9177943.
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    247. Castell DO. Accurate measurement of gastric acidity. Am J Gastroenterol. 1997 Jan; 92(1):181. PMID: 8995974.
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    248. DeVault KR, Beacham S, Castell DO, Streletz LJ, Ditunno JF. Esophageal sensation in spinal cord-injured patients: balloon distension and cerebral evoked potential recording. Am J Physiol. 1996 Dec; 271(6 Pt 1):G937-41. PMID: 8997236.
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    249. Mathias SD, Castell DO, Elkin EP, Matosian ML. Health-related quality of life of patients with acute erosive reflux esophagitis. Dig Dis Sci. 1996 Nov; 41(11):2123-9. PMID: 8943962.
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    250. Castell DO. "Pill esophagitis"--the case of alendronate. N Engl J Med. 1996 Oct 03; 335(14):1058-9. PMID: 8793934.
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    251. Katzka DA, Paoletti V, Leite L, Castell DO. Prolonged ambulatory pH monitoring in patients with persistent gastroesophageal reflux disease symptoms: testing while on therapy identifies the need for more aggressive anti-reflux therapy. Am J Gastroenterol. 1996 Oct; 91(10):2110-3. PMID: 8855731.
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    252. Peghini PL, Johnston BT, Leite LP, Castell DO. Mucosal acid exposure sensitizes a subset of normal subjects to intra-oesophageal balloon distension. Eur J Gastroenterol Hepatol. 1996 Oct; 8(10):979-83. PMID: 8930562.
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    253. Castell DO, Richter JE, Robinson M, Sontag SJ, Haber MM. Efficacy and safety of lansoprazole in the treatment of erosive reflux esophagitis. The Lansoprazole Group. Am J Gastroenterol. 1996 Sep; 91(9):1749-57. PMID: 8792693.
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    254. Schnatz PF, Castell JA, Castell DO. Pulmonary symptoms associated with gastroesophageal reflux: use of ambulatory pH monitoring to diagnose and to direct therapy. Am J Gastroenterol. 1996 Sep; 91(9):1715-8. PMID: 8792686.
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    255. Siddiqui MA, Johnston BT, Leite LP, Katzka DA, Castell DO. Sensitization of esophageal mucosa by prior acid infusion: effect of decreasing intervals between infusions. Am J Gastroenterol. 1996 Sep; 91(9):1745-8. PMID: 8792692.
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    256. Leite LP, Johnston BT, Just RJ, Castell DO. Persistent acid secretion during omeprazole therapy: a study of gastric acid profiles in patients demonstrating failure of omeprazole therapy. Am J Gastroenterol. 1996 Aug; 91(8):1527-31. PMID: 8759655.
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    257. Just RJ, Leite LP, Castell DO. Changes in overnight fasting intragastric pH show poor correlation with duodenogastric bile reflux in normal subjects. Am J Gastroenterol. 1996 Aug; 91(8):1567-70. PMID: 8759663.
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    258. Kuo B, Castell DO. Optimal dosing of omeprazole 40 mg daily: effects on gastric and esophageal pH and serum gastrin in healthy controls. Am J Gastroenterol. 1996 Aug; 91(8):1532-8. PMID: 8759656.
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    259. Castell DO. Obesity and gastro-oesophageal reflux: is there a relationship? Eur J Gastroenterol Hepatol. 1996 Jul; 8(7):625-6. PMID: 8853247.
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    260. Decktor DL, Krawet SH, Rodriguez SL, Robinson M, Castell DO. Dual site ambulatory pH monitoring: a probe across the lower esophageal sphincter does not induce gastroesophageal reflux. Am J Gastroenterol. 1996 Jun; 91(6):1162-6. PMID: 8651164.
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    261. Johnston BT, Troshinsky MB, Castell JA, Castell DO. Comparison of barium radiology with esophageal pH monitoring in the diagnosis of gastroesophageal reflux disease. Am J Gastroenterol. 1996 Jun; 91(6):1181-5. PMID: 8651167.
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    262. Castell DO. Omeprazole works best when used properly. Eur J Gastroenterol Hepatol. 1996 May; 8(5):413-4. PMID: 8804865.
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    263. Castell DO, Katzka DA. Botulinum toxin for achalasia: to be or not to be? Gastroenterology. 1996 May; 110(5):1650-2. PMID: 8613076.
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    264. Johnston BT, Gideon RM, Castell DO. Excluding gastroesophageal reflux disease as the cause of chronic cough. J Clin Gastroenterol. 1996 Apr; 22(3):168-9. PMID: 8724250.
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    265. Castell DO, Johnston BT. Gastroesophageal reflux disease. Current strategies for patient management. Arch Fam Med. 1996 Apr; 5(4):221-7. PMID: 8769911.
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    266. Fennerty MB, Castell D, Fendrick AM, Halpern M, Johnson D, Kahrilas PJ, Leiberman D, Richter JE, Sampliner RE. The diagnosis and treatment of gastroesophageal reflux disease in a managed care environment, Suggested disease management guidelines. Arch Intern Med. 1996 Mar 11; 156(5):477-84. PMID: 8604953.
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    267. Castell JA, Castell DO. Upper esophageal sphincter and pharyngeal function and oropharyngeal (transfer) dysphagia. Gastroenterol Clin North Am. 1996 Mar; 25(1):35-50. PMID: 8682577.
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    268. Leite LP, Johnston BT, Castell DO. Perspectives on esophageal manometry: "lumpers versus splitters". Gastroenterology. 1995 Dec; 109(6):2053-5. PMID: 7498681.
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    269. Leite LP, Johnston BT, Castell DO. Omeprazole for the treatment of posterior laryngitis. Am J Med. 1995 Dec; 99(6):694-5. PMID: 7503099.
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    270. Johnston BT, Castell DO. Intra-oesophageal balloon distension and oesophageal sensation in humans. Eur J Gastroenterol Hepatol. 1995 Dec; 7(12):1221-9. PMID: 8789316.
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    271. DeVault KR, Castell DO. Guidelines for the diagnosis and treatment of gastroesophageal reflux disease. Practice Parameters Committee of the American College of Gastroenterology. Arch Intern Med. 1995 Nov 13; 155(20):2165-73. PMID: 7487238.
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    272. Castell DO, Schnatz PF. Gastroesophageal reflux disease and asthma. Reflux or reflex? Chest. 1995 Nov; 108(5):1186-7. PMID: 7587408.
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    273. Johnston BT, Li Q, Castell JA, Castell DO. Swallowing and esophageal function in Parkinson's disease. Am J Gastroenterol. 1995 Oct; 90(10):1741-6. PMID: 7572887.
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    274. Leite LP, Just RJ, Castell DO, Lagerström PO. Control of gastric acid with high dose H2-receptor antagonists after omeprazole failure: report of two cases. Am J Gastroenterol. 1995 Oct; 90(10):1874-7. PMID: 7572913.
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    275. Kuo B, Castell DO. The effect of nasogastric intubation on gastroesophageal reflux: a comparison of different tube sizes. Am J Gastroenterol. 1995 Oct; 90(10):1804-7. PMID: 7572898.
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    276. Howden CW, Castell DO, Cohen S, Freston JW, Orlando RC, Robinson M. The rationale for continuous maintenance treatment of reflux esophagitis. Arch Intern Med. 1995 Jul 24; 155(14):1465-71. PMID: 7605147.
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    277. Bough ID, Sataloff RT, Castell DO, Hills JR, Gideon RM, Spiegel JR. Gastroesophageal reflux laryngitis resistant to omeprazole therapy. J Voice. 1995 Jun; 9(2):205-11. PMID: 7620543.
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    278. Johnston BT, Leite LP, Castell DO. The gold standard for assessing symptom associations. Gastroenterology. 1995 Jun; 108(6):1959-61. PMID: 7768409.
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    279. Nguyen P, Lee SD, Castell DO. Evidence of gender differences in esophageal pain threshold. Am J Gastroenterol. 1995 Jun; 90(6):901-5. PMID: 7771417.
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    280. Olsson R, Castell JA, Castell DO, Ekberg O. Solid-state computerized manometry improves diagnostic yield in pharyngeal dysphagia: simultaneous videoradiography and manometry in dysphagia patients with normal barium swallows. Abdom Imaging. 1995 May-Jun; 20(3):230-5. PMID: 7620413.
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    281. Leite LP, Castell DO. Ambulatory esophageal manometry in the evaluation of unexplained chest pain. Dig Dis. 1995 May-Jun; 13(3):145-52. PMID: 8548978.
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    282. Castell DO. Commentary: Over-the-Counter H(2)-Receptor Antagonists: Perhaps the Time Has Come! Am J Ther. 1995 May; 2(5):303. PMID: 11850667.
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    283. Katzka DA, Sidhu M, Castell DO. Hypertensive lower esophageal sphincter pressures and gastroesophageal reflux: an apparent paradox that is not unusual. Am J Gastroenterol. 1995 Feb; 90(2):280-4. PMID: 7847301.
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    284. Gideon RM, Paoletti V, Castell DO. Omeprazole, serum gastrin, and gastric acid suppression. Ann Intern Med. 1995 Feb 01; 122(3):237-8. PMID: 7810948.
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    285. Castell DO. Treatment of acid reflux. N Engl J Med. 1995 Jan 19; 332(3):190. PMID: 7702656.
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    286. Castell JA, Castell DO, Duranceau CA, Topart P. Manometric characteristics of the pharynx, upper esophageal sphincter, esophagus, and lower esophageal sphincter in patients with oculopharyngeal muscular dystrophy. Dysphagia. 1995; 10(1):22-6. PMID: 7859528.
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    287. Just R, Katzka DA, Castell DO. Omeprazole failure in a patient with gastroesophageal reflux disease. Ann Intern Med. 1994 Dec 01; 121(11):899. PMID: 7978711.
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    288. Gastal OL, Castell JA, Castell DO. Frequency and site of gastroesophageal reflux in patients with chest symptoms. Studies using proximal and distal pH monitoring. Chest. 1994 Dec; 106(6):1793-6. PMID: 7988202.
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    289. Aisenberg J, Castell DO. Approach to the patient with unexplained chest pain. Mt Sinai J Med. 1994 Nov; 61(6):476-83. PMID: 7838162.
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    290. Just RJ, Castell DO. Chest pain of undetermined origin. Gastrointest Endosc Clin N Am. 1994 Oct; 4(4):731-46. PMID: 7812644.
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    291. DeVault KR, Castell DO. Current diagnosis and treatment of gastroesophageal reflux disease. Mayo Clin Proc. 1994 Sep; 69(9):867-76. PMID: 8065190.
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    292. Lasch H, DeVault KR, Castell DO. Intraesophageal balloon distention in the evaluation of sensory thresholds: studies on reproducibility and comparison of balloon composition. Am J Gastroenterol. 1994 Aug; 89(8):1185-90. PMID: 8053432.
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    293. Wo JM, Castell DO. Exclusion of meal periods from ambulatory 24-hour pH monitoring may improve diagnosis of esophageal acid reflux. Dig Dis Sci. 1994 Aug; 39(8):1601-7. PMID: 8050306.
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    294. Nguyen P, Castell DO. Stimulation of esophageal mechanoreceptors is dependent on rate and duration of distension. Am J Physiol. 1994 Jul; 267(1 Pt 1):G115-8. PMID: 8048523.
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    295. Katzka DA, Castell DO. Successful elimination of reflux symptoms does not insure adequate control of acid reflux in patients with Barrett's esophagus. Am J Gastroenterol. 1994 Jul; 89(7):989-91. PMID: 8017396.
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    296. Troshinsky MB, Kane GC, Varga J, Cater JR, Fish JE, Jimenez SA, Castell DO. Pulmonary function and gastroesophageal reflux in systemic sclerosis. Ann Intern Med. 1994 Jul 01; 121(1):6-10. PMID: 8198350.
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    297. Katz LC, Just R, Castell DO. Body position affects recumbent postprandial reflux. J Clin Gastroenterol. 1994 Jun; 18(4):280-3. PMID: 8071510.
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    298. Li Q, Castell JA, Castell DO. Manometric determination of esophageal length. Am J Gastroenterol. 1994 May; 89(5):722-5. PMID: 8172145.
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    299. Castell JA, Castell DO. Manometric analysis of the pharyngo-esophageal segment. Indian J Gastroenterol. 1994 Apr; 13(2):58-63. PMID: 8206539.
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    300. Nguyen P, Gideon RM, Castell DO. Dysphagia lusoria in the adult: associated esophageal manometric findings and diagnostic use of scanning techniques. Am J Gastroenterol. 1994 Apr; 89(4):620-3. PMID: 8147370.
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    301. Castell DO. Long-term management of GERD: the pill, the knife, or the endoscope? Gastrointest Endosc. 1994 Mar-Apr; 40(2 Pt 1):252-3. PMID: 7912211.
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    302. Castell JA, Stumacher SG, Castell DO. Approach to patients with oropharyngeal dysphagia. Gastroenterologist. 1994 Mar; 2(1):14-9. PMID: 8055227.
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    303. Castell DO, Castell JA. Abnormal proximal esophageal function in achalasia. Dysphagia. 1994; 9(1):20-1. PMID: 8131420.
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    304. DeVault KR, Beacham S, Streletz LJ, Castell DO. Cerebral evoked potentials. A method of quantification of central nervous system response to esophageal pain. Dig Dis Sci. 1993 Dec; 38(12):2241-6. PMID: 8261828.
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    305. Just R, Katz L, Verhille M, Schlagheck T, Castell D. A comparison of the effect of olestra and triglyceride on postprandial esophageal acid exposure. Am J Gastroenterol. 1993 Oct; 88(10):1734-7. PMID: 8213716.
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    306. Castell DO. The nutcracker and the ostrich. Am J Gastroenterol. 1993 Aug; 88(8):1287-8. PMID: 8123087.
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    307. DeVault KR, Georgeson S, Castell DO. Salivary stimulation mimics esophageal exposure to refluxed duodenal contents. Am J Gastroenterol. 1993 Jul; 88(7):1040-3. PMID: 8317402.
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    308. Miller LS, Liu JB, Klenn PJ, Holahan MP, Varga J, Feld RI, Troshinsky M, Jimenez SA, Castell DO, Goldberg BB. Endoluminal ultrasonography of the distal esophagus in systemic sclerosis. Gastroenterology. 1993 Jul; 105(1):31-9. PMID: 8514059.
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    309. Yarze JC, Varga J, Stampfl D, Castell DO, Jimenez SA. Esophageal function in systemic sclerosis: a prospective evaluation of motility and acid reflux in 36 patients. Am J Gastroenterol. 1993 Jun; 88(6):870-6. PMID: 8503383.
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    310. Langevin S, DeNuna SF, Castell DO. Does diet affect values obtained during prolonged ambulatory pressure monitoring. Dig Dis Sci. 1993 Feb; 38(2):225-32. PMID: 8425435.
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    311. Castell JA, Castell DO. Modern solid state computerized manometry of the pharyngoesophageal segment. Dysphagia. 1993; 8(3):270-5. PMID: 8359050.
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    312. Castell DO. Manometric evaluation of the pharynx. Dysphagia. 1993; 8(4):337-8. PMID: 8269726.
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    313. Dobhan R, Castell DO. Normal and abnormal proximal esophageal acid exposure: results of ambulatory dual-probe pH monitoring. Am J Gastroenterol. 1993 Jan; 88(1):25-9. PMID: 8420269.
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    314. Castell JA, Castell DO, Schultz AR, Georgeson S. Effect of head position on the dynamics of the upper esophageal sphincter and pharynx. Dysphagia. 1993; 8(1):1-6. PMID: 8436016.
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    315. Dudnick RS, Castell JA, Castell DO. Abnormal upper esophageal sphincter function in achalasia. Am J Gastroenterol. 1992 Dec; 87(12):1712-5. PMID: 1449131.
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    316. Castell DO. Idiopathic achalasia: are there different types? Am J Gastroenterol. 1992 Dec; 87(12):1693-4. PMID: 1449127.
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    317. Liu JB, Miller LS, Goldberg BB, Feld RI, Alexander AA, Needleman L, Castell DO, Klenn PJ, Millward CL. Transnasal US of the esophagus: preliminary morphologic and function studies. Radiology. 1992 Sep; 184(3):721-7. PMID: 1509056.
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    318. Cassidy KT, Geisinger KR, Kraus BB, Castell DO. Continuous versus intermittent acid exposure in production of esophagitis in feline model. Dig Dis Sci. 1992 Aug; 37(8):1206-11. PMID: 1499444.
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    319. Dobhan R, Castell DO. Prolonged intraesophageal pH monitoring with 16-hr overnight recording. Comparison with "24-hr" analysis. Dig Dis Sci. 1992 Jun; 37(6):857-64. PMID: 1587190.
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    320. Castell DO. Chest pain of undetermined origin: overview of pathophysiology. Am J Med. 1992 May 27; 92(5A):2S-4S. PMID: 1595759.
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    321. DeVault KR, Castell DO. Esophageal balloon distention and cerebral evoked potential recording in the evaluation of unexplained chest pain. Am J Med. 1992 May 27; 92(5A):20S-26S. PMID: 1595760.
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    322. Castell DO, Dalton CB, Becker D, Sinclair J, Castell JA. Alginic acid decreases postprandial upright gastroesophageal reflux. Comparison with equal-strength antacid. Dig Dis Sci. 1992 Apr; 37(4):589-93. PMID: 1551350.
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    323. Fulp SR, Castell DO. Manometric aspects of Zenker's diverticulum. Hepatogastroenterology. 1992 Apr; 39(2):123-6. PMID: 1634178.
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    324. Smout AJ, Devore MS, Dalton CB, Castell DO. Effects of nifedipine on esophageal tone and perception of esophageal distension. Dig Dis Sci. 1992 Apr; 37(4):598-602. PMID: 1551352.
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    325. DeVault KR, Miller LS, Yaghsezian H, Spirig AM, Dhuria M, Armenti FR, Connell DC, Martin P, Castell DO. Acute esophageal hemorrhage from a vagal neurilemoma. Gastroenterology. 1992 Mar; 102(3):1059-61. PMID: 1537496.
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    326. DeVault K, Castell DO. The irritable stomach syndrome. Am J Gastroenterol. 1992 Mar; 87(3):399-400. PMID: 1539583.
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    327. Smout AJ, DeVore MS, Dalton CB, Castell DO. Cerebral potentials evoked by oesophageal distension in patients with non-cardiac chest pain. Gut. 1992 Mar; 33(3):298-302. PMID: 1568646.
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    328. Sato TL, Wu WC, Castell DO. Randomized, double-blind, placebo-controlled crossover trial of pirenzepine in patients with gastroesophageal reflux. Dig Dis Sci. 1992 Feb; 37(2):297-302. PMID: 1735350.
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    329. Castell DO. Esophageal manometry in the evaluation of esophageal symptoms. Dysphagia. 1992; 7(1):1-2. PMID: 1424822.
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    330. Sears VW, Castell JA, Castell DO. Radial and longitudinal asymmetry of human pharyngeal pressures during swallowing. Gastroenterology. 1991 Dec; 101(6):1559-63. PMID: 1955121.
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    331. Langevin S, Castell DO. Esophageal motility disorders and chest pain. Med Clin North Am. 1991 Sep; 75(5):1045-63. PMID: 1895805.
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    332. Dalton CB, Castell DO, Hewson EG, Wu WC, Richter JE. Diffuse esophageal spasm. A rare motility disorder not characterized by high-amplitude contractions. Dig Dis Sci. 1991 Aug; 36(8):1025-8. PMID: 1864192.
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    333. Mendez L, Friedman LS, Castell DO. Swallowing disorders in the elderly. Clin Geriatr Med. 1991 May; 7(2):215-30. PMID: 1855155.
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    334. Kitchin LI, Castell DO. Rationale and efficacy of conservative therapy for gastroesophageal reflux disease. Arch Intern Med. 1991 Mar; 151(3):448-54. PMID: 1672062.
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    335. Cattau EL, Castell DO, Johnson DA, Spurling TJ, Hirszel R, Chobanian SJ, Richter JE. Diltiazem therapy for symptoms associated with nutcracker esophagus. Am J Gastroenterol. 1991 Mar; 86(3):272-6. PMID: 1998307.
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    336. Hylander BI, Dalton CB, Castell DO, Burkart J, Rössner S. Effect of intraperitoneal fluid volume changes on esophageal pressures: studies in patients on continuous ambulatory peritoneal dialysis. Am J Kidney Dis. 1991 Mar; 17(3):307-10. PMID: 1996574.
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    337. DeVault KR, Castell DO. A simplified technique for accurate placement of ambulatory pH probes. Am J Gastroenterol. 1991 Mar; 86(3):380-1. PMID: 1998325.
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    338. Castell DO. Rationale for high-dose H2-receptor blockade in the treatment of gastro-oesophageal reflux disease. Aliment Pharmacol Ther. 1991; 5 Suppl 1:59-67. PMID: 1679673.
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    339. Fulp SR, Dalton CB, Castell JA, Castell DO. Aging-related alterations in human upper esophageal sphincter function. Am J Gastroenterol. 1990 Dec; 85(12):1569-72. PMID: 2252018.
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    340. Dalton CB, Hewson EG, Castell DO, Richter JE. Edrophonium provocative test in noncardiac chest pain. Evaluation of testing techniques. Dig Dis Sci. 1990 Dec; 35(12):1445-51. PMID: 2253528.
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    341. Smout AJ, DeVore MS, Castell DO. Cerebral potentials evoked by esophageal distension in human. Am J Physiol. 1990 Dec; 259(6 Pt 1):G955-9. PMID: 2260664.
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    342. Mattox HE, Albertson DA, Castell DO, Richter JE. Dysphagia following fundoplication: "slipped" fundoplication versus achalasia complicated by fundoplication. Am J Gastroenterol. 1990 Nov; 85(11):1468-72. PMID: 2239875.
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    343. Stark GA, Castell DO, Richter JE, Wu WC. Prospective randomized comparison of Brown-McHardy and microvasive balloon dilators in treatment of achalasia. Am J Gastroenterol. 1990 Oct; 85(10):1322-6. PMID: 2220722.
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    344. Miller LS, Castell DO. Use of endoscopic laser therapy to prevent reflux. Gastrointest Endosc. 1990 Sep-Oct; 36(5):531-2. PMID: 2227336.
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    345. Geisinger KR, Cassidy KT, Nardi R, Castell DO. The histologic development of acid-induced esophagitis in the cat. Mod Pathol. 1990 Sep; 3(5):619-24. PMID: 2235988.
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    346. Sears VW, Castell JA, Castell DO. Comparison of effects of upright versus supine body position and liquid versus solid bolus on esophageal pressures in normal humans. Dig Dis Sci. 1990 Jul; 35(7):857-64. PMID: 2364840.
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    347. Geisinger KR, Scobey MW, Northway MG, Cassidy KT, Castell DO. Radiation-induced proctitis cystica profunda in the rat. Dig Dis Sci. 1990 Jul; 35(7):833-9. PMID: 2364837.
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    348. Kraus BB, Wu WC, Castell DO. Comparison of lower esophageal sphincter manometrics and gastroesophageal reflux measured by 24-hour pH recording. Am J Gastroenterol. 1990 Jun; 85(6):692-6. PMID: 2353688.
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    349. Knauer CM, Castell JA, Dalton CB, Nowak L, Castell DO. Pharyngeal/upper esophageal sphincter pressure dynamics in humans. Effects of pharmacologic agents and thermal stimulation. Dig Dis Sci. 1990 Jun; 35(6):774-80. PMID: 2344812.
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    350. Castell DO. Esophageal disorders in the elderly. Gastroenterol Clin North Am. 1990 Jun; 19(2):235-54. PMID: 2194944.
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    351. Castell DO. The gastroenterologist and microvascular angina. Gastroenterology. 1990 Apr; 98(4):1103-5. PMID: 2311868.
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    352. Kraus BB, Sinclair JW, Castell DO. Gastroesophageal reflux in runners. Characteristics and treatment. Ann Intern Med. 1990 Mar 15; 112(6):429-33. PMID: 2178535.
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    353. Castell DO, Wood JD, Frieling T, Wright FS, Vieth RF. Cerebral electrical potentials evoked by balloon distention of the human esophagus. Gastroenterology. 1990 Mar; 98(3):662-6. PMID: 2298370.
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    354. Castell JA, Dalton CB, Castell DO. Pharyngeal and upper esophageal sphincter manometry in humans. Am J Physiol. 1990 Feb; 258(2 Pt 1):G173-8. PMID: 2305883.
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    355. Castell JA, Dalton CB, Castell DO. Effects of body position and bolus consistency on the manometric parameters and coordination of the upper esophageal sphincter and pharynx. Dysphagia. 1990; 5(4):179-86. PMID: 2272216.
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    356. Fulp SR, Castell DO. Scleroderma esophagus. Dysphagia. 1990; 5(4):204-10. PMID: 2272219.
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    357. Wiener GJ, Koufman JA, Wu WC, Cooper JB, Richter JE, Castell DO. Chronic hoarseness secondary to gastroesophageal reflux disease: documentation with 24-h ambulatory pH monitoring. Am J Gastroenterol. 1989 Dec; 84(12):1503-8. PMID: 2596451.
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    358. Becker DJ, Castell DO. Acute airway obstruction in achalasia. Possible role of defective belch reflex. Gastroenterology. 1989 Nov; 97(5):1323-6. PMID: 2676685.
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    359. Castell DO, Holtz A. Gastroesophageal reflux. Don't forget to ask about heartburn. Postgrad Med. 1989 Oct; 86(5):141-4, 147-8. PMID: 2678058.
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    360. Wang JC, Castell DO, Sinclair JW, Wu WC. Does sleeping on a waterbed promote gastroesophageal reflux? Dig Dis Sci. 1989 Oct; 34(10):1585-9. PMID: 2791810.
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    361. Semble EL, Wu WC, Castell DO. Nonsteroidal antiinflammatory drugs and esophageal injury. Semin Arthritis Rheum. 1989 Oct; 19(2):99-109. PMID: 2683094.
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    362. Richter JE, Castell DO. 24 hour ambulatory oesophageal motility monitoring: how should motility data be analysed? Gut. 1989 Aug; 30(8):1040-7. PMID: 2767498.
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    363. Murphy DW, Faust KB, Chiantella VM, Castell DO. Assessment of accuracy of intraesophageal pH probe in a dog model. Dig Dis Sci. 1989 Jul; 34(7):1079-84. PMID: 2743847.
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    364. Becker DJ, Sinclair J, Castell DO, Wu WC. A comparison of high and low fat meals on postprandial esophageal acid exposure. Am J Gastroenterol. 1989 Jul; 84(7):782-6. PMID: 2741888.
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    365. Castell DO. Asthma and gastroesophageal reflux. Chest. 1989 Jul; 96(1):2-3. PMID: 2736977.
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    366. Clark CS, Kraus BB, Sinclair J, Castell DO. Gastroesophageal reflux induced by exercise in healthy volunteers. JAMA. 1989 Jun 23-30; 261(24):3599-601. PMID: 2724505.
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    367. Murphy DW, Yuan Y, Castell DO. Does the intraesophageal pH probe accurately detect acid reflux? Simultaneous recording with two pH probes in humans. Dig Dis Sci. 1989 May; 34(5):649-56. PMID: 2714140.
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    368. Waterman DC, Dalton CB, Ott DJ, Castell JA, Bradley LA, Castell DO, Richter JE. Hypertensive lower esophageal sphincter: what does it mean? J Clin Gastroenterol. 1989 Apr; 11(2):139-46. PMID: 2661657.
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    369. Hewson EG, Sinclair JW, Dalton CB, Wu WC, Castell DO, Richter JE. Acid perfusion test: does it have a role in the assessment of non cardiac chest pain? Gut. 1989 Mar; 30(3):305-10. PMID: 2707630.
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    370. Chen YM, Ott DJ, Hewson EG, Richter JE, Wu WC, Gelfand DW, Castell DO. Diffuse esophageal spasm: radiographic and manometric correlation. Radiology. 1989 Mar; 170(3 Pt 1):807-10. PMID: 2916033.
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    371. Waterman DC, Castell DO. Chest pain and inability to belch. Gastroenterology. 1989 Jan; 96(1):274-5. PMID: 2909435.
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    372. Ott DJ, Richter JE, Chen YM, Wu WC, Gelfand DW, Castell DO. Radiographic and manometric correlation in achalasia with apparent relaxation of the lower esophageal sphincter. Gastrointest Radiol. 1989; 14(1):1-5. PMID: 2910741.
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    373. Richter JE, Castell DO. Chest pain of esophageal origin. Dig Dis. 1989; 7(1):39-50. PMID: 2647322.
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    374. Richter JE, Bradley LA, Castell DO. Esophageal chest pain: current controversies in pathogenesis, diagnosis, and therapy. Ann Intern Med. 1989 Jan 01; 110(1):66-78. PMID: 2642283.
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    375. Castell JA, Dalton CB, Castell DO. On-line computer analysis of human lower esophageal sphincter relaxation. Am J Physiol. 1988 Dec; 255(6 Pt 1):G794-9. PMID: 3202172.
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    376. Dubois A, Nompleggi D, Castell DO. Histamine H2 receptor stimulation increases gastric emptying in monkeys. Am J Physiol. 1988 Dec; 255(6 Pt 1):G767-71. PMID: 2974243.
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    377. Wiener GJ, Morgan TM, Copper JB, Wu WC, Castell DO, Sinclair JW, Richter JE. Ambulatory 24-hour esophageal pH monitoring. Reproducibility and variability of pH parameters. Dig Dis Sci. 1988 Sep; 33(9):1127-33. PMID: 3044715.
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    378. Castell DO. Gastroesophageal reflux--the great imitator. West J Med. 1988 Jul; 149(1):81-2. PMID: 3407165.
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    379. Murphy DW, Castell DO. Chocolate and heartburn: evidence of increased esophageal acid exposure after chocolate ingestion. Am J Gastroenterol. 1988 Jun; 83(6):633-6. PMID: 3376917.
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    380. Dalton CB, Castell DO, Richter JE. The changing faces of the nutcracker esophagus. Am J Gastroenterol. 1988 Jun; 83(6):623-8. PMID: 3376915.
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    381. Nelson JB, Castell DO. Esophageal motility disorders. Dis Mon. 1988 Jun; 34(6):297-389. PMID: 3292177.
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    382. Peters L, Maas L, Petty D, Dalton C, Penner D, Wu W, Castell D, Richter J. Spontaneous noncardiac chest pain. Evaluation by 24-hour ambulatory esophageal motility and pH monitoring. Gastroenterology. 1988 Apr; 94(4):878-86. PMID: 3345887.
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    383. Wiener GJ, Richter JE, Copper JB, Wu WC, Castell DO. The symptom index: a clinically important parameter of ambulatory 24-hour esophageal pH monitoring. Am J Gastroenterol. 1988 Apr; 83(4):358-61. PMID: 3348191.
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    384. Holtz A, Castell DO. Chest pain associated with esophageal disease. Postgrad Med. 1988 Apr; 83(5):315-20. PMID: 3357867.
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    385. Katz PO, Geisinger KR, Hassan M, Wu WC, Huang D, Castell DO. Acid-induced esophagitis in cats is prevented by sucralfate but not synthetic prostaglandin E. Dig Dis Sci. 1988 Feb; 33(2):217-24. PMID: 3338369.
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    386. Gonzalez ER, Castell DO. Respiratory complications of gastroesophageal reflux. Am Fam Physician. 1988 Feb; 37(2):169-72. PMID: 2894146.
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    387. Richter JE, Castell DO. Esophageal disease as a cause of noncardiac chest pain. Adv Intern Med. 1988; 33:311-35. PMID: 3278509.
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    388. Peters LJ, Castell DO. Motility disorders of the esophagus. Compr Ther. 1988 Jan; 14(1):19-23. PMID: 2830076.
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    389. Green WE, Castell JA, Castell DO. Upper esophageal sphincter pressure recording: is an oval manometry catheter necessary? Dysphagia. 1988; 2(3):162-5. PMID: 3251691.
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    390. Castell DO. Long-term therapy for chronic gastroesophageal reflux. Arch Intern Med. 1987 Oct; 147(10):1701-2. PMID: 3116958.
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    391. Clark S, Katz PO, Wu WC, Geisinger KR, Castell DO. Comparison of potential cytoprotective action of sucralfate and cimetidine. Studies with experimental feline esophagitis. Am J Med. 1987 Sep 28; 83(3B):56-60. PMID: 3661611.
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    392. Caldwell JR, Roth SH, Wu WC, Semble EL, Castell DO, Heller MD, Marsh WH. Sucralfate treatment of nonsteroidal anti-inflammatory drug-induced gastrointestinal symptoms and mucosal damage. Am J Med. 1987 Sep 28; 83(3B):74-82. PMID: 3310631.
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    393. Williams RM, Orlando RC, Bozymski EM, Readling RD, Castell DO, Roufail WM, Rick GG, Rubin SE, Sinar DR. Multicenter trial of sucralfate suspension for the treatment of reflux esophagitis. Am J Med. 1987 Sep 28; 83(3B):61-6. PMID: 3310630.
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    394. Ott DJ, Richter JE, Wu WC, Chen YM, Castell DO, Gelfand DW. Radiographic evaluation of esophagus immediately after pneumatic dilatation for achalasia. Dig Dis Sci. 1987 Sep; 32(9):962-7. PMID: 3622190.
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    395. Ott DJ, Richter JE, Chen YM, Wu WC, Gelfand DW, Castell DO. Esophageal radiography and manometry: correlation in 172 patients with dysphagia. AJR Am J Roentgenol. 1987 Aug; 149(2):307-11. PMID: 3496755.
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    396. Wong RK, Maydonovitch C, Garcia JE, Johnson LF, Castell DO. The effect of terbutaline sulfate, nitroglycerin, and aminophylline on lower esophageal sphincter pressure and radionuclide esophageal emptying in patients with achalasia. J Clin Gastroenterol. 1987 Aug; 9(4):386-9. PMID: 3116071.
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    397. Castell DO, Richter JE. Edrophonium testing for esophageal pain. Concurrence and discord. Dig Dis Sci. 1987 Aug; 32(8):897-9. PMID: 3608734.
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    398. De Vault K, Castell J, Castell D. How many swallows are required to establish reliable esophageal peristaltic parameters in normal subjects? An on-line computer analysis. Am J Gastroenterol. 1987 Aug; 82(8):754-7. PMID: 3605034.
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    399. Richter JE, Geisinger KR, Castell DO. Surveillance for Barrett's esophagus. Gastroenterology. 1987 Jul; 93(1):220-1. PMID: 3582911.
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    400. Richter JE, Dalton CB, Bradley LA, Castell DO. Oral nifedipine in the treatment of noncardiac chest pain in patients with the nutcracker esophagus. Gastroenterology. 1987 Jul; 93(1):21-8. PMID: 3582908.
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    401. Richter JE, Wu WC, Johns DN, Blackwell JN, Nelson JL, Castell JA, Castell DO. Esophageal manometry in 95 healthy adult volunteers. Variability of pressures with age and frequency of "abnormal" contractions. Dig Dis Sci. 1987 Jun; 32(6):583-92. PMID: 3568945.
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    402. DeVault KR, Castell DO. Effects of antireflux therapies on salivary function in normal humans. Dig Dis Sci. 1987 Jun; 32(6):603-8. PMID: 3568947.
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    403. Katz PO, Dalton CB, Richter JE, Wu WC, Castell DO. Esophageal testing of patients with noncardiac chest pain or dysphagia. Results of three years' experience with 1161 patients. Ann Intern Med. 1987 Apr; 106(4):593-7. PMID: 3826958.
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    404. Ward BW, Wu WC, Richter JE, Hackshaw BT, Castell DO. Long-term follow-up of symptomatic status of patients with noncardiac chest pain: is diagnosis of esophageal etiology helpful? Am J Gastroenterol. 1987 Mar; 82(3):215-8. PMID: 3826028.
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    405. Richter JE, Blackwell JN, Wu WC, Johns DN, Cowan RJ, Castell DO. Relationship of radionuclide liquid bolus transport and esophageal manometry. J Lab Clin Med. 1987 Feb; 109(2):217-24. PMID: 3805872.
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    406. Richter JE, Castell DO. Surgical myotomy for nutcracker esophagus. To be or not to be? Dig Dis Sci. 1987 Jan; 32(1):95-6. PMID: 3792184.
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    407. Castell DO, Richter JE. Editorial: esophageal symptoms and the "irritable esophagus". Dysphagia. 1987; 2(2):109-11. PMID: 3507294.
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    408. Castell DO, Donner MW. Evaluation of dysphagia: a careful history is crucial. Dysphagia. 1987; 2(2):65-71. PMID: 3507297.
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    409. Barish CF, Castell DO, Richter JE. Graded esophageal balloon distention. A new provocative test for noncardiac chest pain. Dig Dis Sci. 1986 Dec; 31(12):1292-8. PMID: 3803130.
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    410. Castell JA, Castell DO. Computer analysis of human esophageal peristalsis and lower esophageal sphincter pressure. II. An interactive system for on-line data collection and analysis. Dig Dis Sci. 1986 Nov; 31(11):1211-6. PMID: 3769705.
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    411. Richter JE, Barish CF, Castell DO. Abnormal sensory perception in patients with esophageal chest pain. Gastroenterology. 1986 Oct; 91(4):845-52. PMID: 3743962.
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    412. Ott DJ, Richter JE, Wu WC, Chen YM, Gelfand DW, Castell DO. Radiologic and manometric correlation in "nutcracker esophagus". AJR Am J Roentgenol. 1986 Oct; 147(4):692-5. PMID: 3489366.
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    413. Katz PO, Knuff TE, Benjamin SB, Castell DO. Abnormal esophageal pressures in reflux esophagitis: cause or effect? Am J Gastroenterol. 1986 Sep; 81(9):744-6. PMID: 3752036.
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    414. Hassan M, Dalton CB, Castell JA, Castell DO. Pirenzepine and propantheline effects on esophageal pressure responses to bethanechol. Am J Gastroenterol. 1986 May; 81(5):334-8. PMID: 2871750.
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    415. Meyer GW, Austin RM, Brady CE, Castell DO. Muscle anatomy of the human esophagus. J Clin Gastroenterol. 1986 Apr; 8(2):131-4. PMID: 3745845.
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    416. Katz PO, Richter JE, Cowan R, Castell DO. Apparent complete lower esophageal sphincter relaxation in achalasia. Gastroenterology. 1986 Apr; 90(4):978-83. PMID: 3949123.
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    417. Castell DO. Dysphagia in the elderly. J Am Geriatr Soc. 1986 Mar; 34(3):248-9. PMID: 3950295.
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    418. Blackwell JN, Dalton CB, Castell DO. Oral pirenzepine does not affect esophageal pressures in man. Dig Dis Sci. 1986 Mar; 31(3):230-5. PMID: 3753924.
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    419. Lanza FL, Smith V, Page-Castell JA, Castell DO. Effectiveness of foaming antacid in relieving induced heartburn. South Med J. 1986 Mar; 79(3):327-30. PMID: 3513329.
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    420. Dubois A, Castell DO. Histamine H2-receptor involvement in the regulation of gastric emptying. Am J Physiol. 1986 Feb; 250(2 Pt 1):G244-7. PMID: 3953804.
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    421. Cohen DJ, Benjamin SB, Graeber GM, Castell DO, Patrick DH, Cordova C, Dachman A, Friedman A. Evaluation of the Angelchik antireflux prosthesis using a model for esophageal reflux in rhesus monkeys. Ann Thorac Surg. 1986 Feb; 41(2):135-42. PMID: 3947163.
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    422. Castell DO. Medical therapy for reflux esophagitis: 1986 and beyond. Ann Intern Med. 1986 Jan; 104(1):112-4. PMID: 2866742.
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    423. Ward BW, Wu WC, Richter JE, Lui KW, Castell DO. Ambulatory 24-hour esophageal pH monitoring. Technology searching for a clinical application. J Clin Gastroenterol. 1986; 8 Suppl 1:59-67. PMID: 3734378.
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    424. Castell DO. Future medical therapy of reflux esophagitis. J Clin Gastroenterol. 1986; 8 Suppl 1:81-5. PMID: 2874169.
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    425. Sinar DR, Carey LC, Cordova C, Fletcher JR, Castell DO. Lidocaine inhibition of esophageal peristalsis and lower esophageal sphincter pressure in baboons. Dig Dis Sci. 1985 Nov; 30(11):1085-91. PMID: 2865090.
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    426. Barish CF, Wu WC, Castell DO. Respiratory complications of gastroesophageal reflux. Arch Intern Med. 1985 Oct; 145(10):1882-8. PMID: 2864025.
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    427. Castell DO. Diagnosis of noncardiac chest pain in older patients. Geriatrics. 1985 Oct; 40(10):61-3, 67, 70 passim. PMID: 4043738.
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    428. Richter JE, Dalton CB, Buice RG, Castell DO. Nifedipine: a potent inhibitor of contractions in the body of the human esophagus. Studies in healthy volunteers and patients with the nutcracker esophagus. Gastroenterology. 1985 Sep; 89(3):549-54. PMID: 4018501.
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    429. Richter JE, Wu WC, Castell DO. Double-peaked contraction waves--a variant of normal. Gastroenterology. 1985 Aug; 89(2):479-80. PMID: 4007432.
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    430. Katz PO, Castell DO. Esophageal motility disorders. Am J Med Sci. 1985 Aug; 290(2):61-9. PMID: 3898840.
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    431. Richter JE, Hackshaw BT, Wu WC, Castell DO. Edrophonium: a useful provocative test for esophageal chest pain. Ann Intern Med. 1985 Jul; 103(1):14-21. PMID: 4003972.
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    432. Richter JE, Johns DN, Wu WC, Castell DO. Are esophageal motility abnormalities produced during the intraesophageal acid perfusion test? JAMA. 1985 Apr 05; 253(13):1914-7. PMID: 3974081.
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    433. Nelson JL, Castell DO. Reflux esophagitis: an update. South Med J. 1985 Apr; 78(4):452-7. PMID: 2858922.
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    434. Castell DO. Esophageal motility disorders: the specter of the spectrum. Dig Dis Sci. 1985 Feb; 30(2):188-9. PMID: 3967566.
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    435. Castell DO. Calcium-channel blocking agents for gastrointestinal disorders. Am J Cardiol. 1985 Jan 25; 55(3):210B-213B. PMID: 3881916.
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    436. Castell DO. Esophageal chest pain. Am J Gastroenterol. 1984 Dec; 79(12):969-71. PMID: 6507423.
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    437. Blackwell JM, Richter JE, Wu WC, Cowan RJ, Castell DO. Esophageal radionuclide transit tests. Potential false-positive results. Clin Nucl Med. 1984 Dec; 9(12):679-83. PMID: 6509841.
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    438. Blackwell JN, Wu WC, Castell DO. Clinical applications of oesophageal motility studies? Br J Hosp Med. 1984 Nov; 32(5):267-71. PMID: 6498377.
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    439. Nelson JL, Richter JE, Johns DN, Castell DO, Centola GM. Esophageal contraction pressures are not affected by normal menstrual cycles. Gastroenterology. 1984 Oct; 87(4):867-71. PMID: 6468874.
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    440. Blackwell JN, Castell DO. Oesophageal motility: recent advances and implications. Clin Sci (Lond). 1984 Aug; 67(2):145-51. PMID: 6378490.
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    441. Winters C, Artnak EJ, Benjamin SB, Castell DO. Esophageal bougienage in symptomatic patients with the nutcracker esophagus. A primary esophageal motility disorder. JAMA. 1984 Jul 20; 252(3):363-6. PMID: 6376833.
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    442. Richter JE, Spurling TJ, Cordova CM, Castell DO. Effects of oral calcium blocker, diltiazem, on esophageal contractions. Studies in volunteers and patients with nutcracker esophagus. Dig Dis Sci. 1984 Jul; 29(7):649-56. PMID: 6734370.
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    443. Curtis DJ, Benjamin SB, Kerr R, Castell DO. Angelchik anti-reflux device: radiographic appearance of complications. Radiology. 1984 May; 151(2):311-3. PMID: 6424173.
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    444. Benjamin SB, Kerr R, Cohen D, Motaparthy V, Castell DO. Complications of the Angelchik antireflux prosthesis. Ann Intern Med. 1984 Apr; 100(4):570-5. PMID: 6367581.
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    445. Knuff TE, Benjamin SB, Worsham GF, Hancock JE, Castell DO. Histologic evaluation of chronic gastroesophageal reflux. An evaluation of biopsy methods and diagnostic criteria. Dig Dis Sci. 1984 Mar; 29(3):194-201. PMID: 6697859.
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    446. Ott DJ, Gelfand DW, Wu WC, Castell DO. Esophagogastric region and its rings. AJR Am J Roentgenol. 1984 Feb; 142(2):281-7. PMID: 6364745.
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    447. Richter JE, Castell DO. Diffuse esophageal spasm: a reappraisal. Ann Intern Med. 1984 Feb; 100(2):242-5. PMID: 6691670.
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    448. Castell DO. Sphincters of the oesophagus. Neth J Med. 1984; 27(7):234-41. PMID: 6387516.
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    449. Blackwell JN, Castell DO. Oesophageal chest pain: a point of view. Gut. 1984 Jan; 25(1):1-6. PMID: 6418620.
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    450. Castell DO, Dubois A, Davis CR, Cordova CM, Norman DO. Computer-Aided analysis of human esophageal peristalsis. I. Technical description and comparison with manual analysis. Dig Dis Sci. 1984 Jan; 29(1):65-72. PMID: 6692733.
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    451. Wu WC, Castell DO. Gastroesophageal reflux. Compr Ther. 1983 Nov; 9(11):57-63. PMID: 6357615.
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    452. Cattau EL, Artnak EJ, Castell DO, Meyer GW. Efficacy of atropine as an endoscopic premedication. Gastrointest Endosc. 1983 Nov; 29(4):285-8. PMID: 6357938.
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    453. Benjamin SB, O'Donnell JK, Hancock J, Nielsen P, Castell DO. Prolonged radionuclide transit in "nutcracker esophagus". Dig Dis Sci. 1983 Sep; 28(9):775-9. PMID: 6884162.
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    454. Benjamin SB, Castell DO, Richter JE. "When is esophageal spasm, spasm?". Gastroenterology. 1983 Jul; 85(1):219-20. PMID: 6852457.
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    455. Benjamin SB, Richter JE, Cordova CM, Knuff TE, Castell DO. Prospective manometric evaluation with pharmacologic provocation of patients with suspected esophageal motility dysfunction. Gastroenterology. 1983 May; 84(5 Pt 1):893-901. PMID: 6832564.
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    456. Hart G, Stokes TC, Harrison BD, Castell D. Erythrapheresis in patients with polycythaemia secondary to hypoxic lung disease. Br Med J (Clin Res Ed). 1983 Apr 16; 286(6373):1284. PMID: 6404430.
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    457. Benjamin SB, Castell DO. Chest pain of esophageal origin. Where are we, and where should we go? Arch Intern Med. 1983 Apr; 143(4):772-6. PMID: 6340626.
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    458. Benjamin SB, Knuff TK, Fink M, Woods E, Castell DO. The Angelchik antireflux prosthesis. Effects on the lower esophageal sphincter of primates. Ann Surg. 1983 Jan; 197(1):63-7. PMID: 6848055.
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    459. Sinar DR, Cordova CM, Fletcher JR, Castell DO. Decreased esophageal peristaltic amplitude in response to prostaglandin E1 and prostacyclin in the baboon. Dig Dis Sci. 1982 Dec; 27(12):1067-72. PMID: 6756831.
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    460. Castell DO. Clinical applications of esophageal manometry. Dig Dis Sci. 1982 Sep; 27(9):769-71. PMID: 7105949.
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    461. Meyer GW, Castell DO. Physiology of the oesophagus. Clin Gastroenterol. 1982 Sep; 11(3):439-51. PMID: 6754168.
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    462. Richter JE, Castell DO. Gastroesophageal reflux. Pathogenesis, diagnosis, and therapy. Ann Intern Med. 1982 Jul; 97(1):93-103. PMID: 6124198.
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    463. Richter JE, Sinar DR, Cordova CM, Castell DO. Verapamil--a potent inhibitor of esophageal contractions in the baboon. Gastroenterology. 1982 May; 82(5 Pt 1):882-6. PMID: 6277726.
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    464. Knuff TE, Benjamin SB, Castell DO. Pharyngoesophageal (Zenker's) diverticulum: a reappraisal. Gastroenterology. 1982 Apr; 82(4):734-6. PMID: 6800871.
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    465. Cattau EL, Benjamin SB, Knuff TE, Castell DO. The accuracy of the physical examination in the diagnosis of suspected ascites. JAMA. 1982 Feb 26; 247(8):1164-6. PMID: 7057606.
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    466. Benjamin SB, Eisold J, Gerhardt DC, Castell DO. Central nervous system lymphoma presenting as dysphagia. Dig Dis Sci. 1982 Feb; 27(2):155-60. PMID: 7075410.
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    467. Cattau EL, Castell DO. Symptoms of esophageal dysfunction. Adv Intern Med. 1982; 27:151-81. PMID: 7041542.
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    468. Meyer GW, Castell DO. Human esophageal response during chest pain induced by swallowing cold liquids. JAMA. 1981 Nov 06; 246(18):2057-9. PMID: 7288992.
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    469. Meyer GW, Castell DO. Evaluation and management of diseases of the esophagus. Am J Otolaryngol. 1981 Nov; 2(4):336-44. PMID: 7034570.
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    470. Richter JE, Castell DO. Drugs, foods, and other substances in the cause and treatment of reflux esophagitis. Med Clin North Am. 1981 Nov; 65(6):1223-34. PMID: 7035766.
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    471. Meyer GW, Castell DO. In support of the clinical usefulness of lower esophageal sphincter pressure determination. Dig Dis Sci. 1981 Nov; 26(11):1028-31. PMID: 7297372.
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    472. Meyer GW, Gerhardt DC, Castell DO. Human esophageal response to rapid swallowing: muscle refractory period or neural inhibition? Am J Physiol. 1981 Aug; 241(2):G129-36. PMID: 7270690.
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    473. Eastwood GL, Beck BD, Castell DO, Brown FC, Fletcher JR. Beneficial effect of indomethacin on acid-induced esophagitis in cats. Dig Dis Sci. 1981 Jul; 26(7):601-8. PMID: 7249895.
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    474. Richter JE, Pandol SJ, Castell DO, McCarthy DM. Gastroesophageal reflux disease in the Zollinger-Ellison syndrome. Ann Intern Med. 1981 Jul; 95(1):37-43. PMID: 7247125.
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    475. Benjamin SB, Castell DO. Achalasia and Hodgkin's disease: a chance association? J Clin Gastroenterol. 1981 Jun; 3(2):175-8. PMID: 7240695.
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    476. Northway MG, Castell DO. Do prostaglandins cause gastrointestinal mucosal injury? Dig Dis Sci. 1981 May; 26(5):453-6. PMID: 7249885.
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    477. Richter JE, Castell DO. Current approaches in the medical treatment of oesophageal reflux. Drugs. 1981 Apr; 21(4):283-91. PMID: 7014172.
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    478. Dubois A, Castell DO. Abnormal gastric emptying response to pentagastrin in duodenal ulcer disease. Dig Dis Sci. 1981 Apr; 26(4):292-6. PMID: 7238257.
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    479. Sinar DR, Fletcher JR, Castell DO. Prostaglandin E1 effects on resting and cholinergically stimulated lower esophageal sphincter pressure in cats. Prostaglandins. 1981 Apr; 21(4):581-90. PMID: 6114513.
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    480. Humphries TJ, Castell DO. Effect of oral bethanechol on parameters of esophageal peristalsis. Dig Dis Sci. 1981 Feb; 26(2):129-32. PMID: 7460715.
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    481. Richter JE, Gerhardt DC, Pasquale DN, Castell DO. Cimetidine and hematologic suppression: things are not always as they appear. Dig Dis Sci. 1980 Dec; 25(12):960-3. PMID: 7449591.
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    482. Castell DO. Medical therapy of reflux esophagitis. Ann Intern Med. 1980 Dec; 93(6):926-7. PMID: 7004295.
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    483. Meyer GW, Castell DO. Current concepts of esophageal function. Am J Otolaryngol. 1980 Nov; 1(5):440-6. PMID: 7457764.
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    484. Castell DO. Medical problems of the VIP. Mil Med. 1980 Jul; 145(7):476-9. PMID: 6772988.
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    485. Shea-Donohue PT, Myers L, Castell DO, Dubois A. Effect of prostacyclin on gastric emptying and secretion in rhesus monkeys. Gastroenterology. 1980 Jun; 78(6):1476-9. PMID: 6768636.
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    486. Castell DO. Esophageal manometric studies: a perspective of their physiologic and clinical relevance. J Clin Gastroenterol. 1980 Jun; 2(2):191-6. PMID: 7440952.
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    487. Gerhardt DC, Castell DO, Winship DH, Shuck TJ. Esophageal dysfunction in esophagopharyngeal regurgitation. Gastroenterology. 1980 May; 78(5 Pt 1):893-7. PMID: 7053042.
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    488. Nompleggi D, Myers L, Castell DO, Dubois A. Effect of a prostaglandin E2 analog on gastric emptying and secretion in rhesus monkeys. J Pharmacol Exp Ther. 1980 Mar; 212(3):491-5. PMID: 6767018.
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    489. Sinar DR, Fletcher JR, Castell DO. Comparison of the effect of continuous intravenous infusion of prostaglandins E1, E2, I, or 6-keto-PGF1 alpha on lower esophageal sphincter pressure. Adv Prostaglandin Thromboxane Res. 1980; 8:1507-10. PMID: 6990721.
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    490. Nompleggi D, Myers L, Ramwell P, Castell D, Dubois A. PGE2 involvement in the regulation of gastric emptying. Adv Prostaglandin Thromboxane Res. 1980; 8:1587-8. PMID: 6769319.
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    491. Shea-Donohue PT, Myers L, Castell DO, Dubois A. Effect of prostacyclin on gastric emptying and secretion in rhesus monkeys. Adv Prostaglandin Thromboxane Res. 1980; 8:1557-8. PMID: 6769318.
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    492. Castell DO. Motor disorders of the esophagus. N Engl J Med. 1979 Nov 15; 301(20):1124. PMID: 492261.
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    493. Chernow B, Johnson LF, Janowitz WR, Castell DO. Pulmonary aspiration as a consequence of gastroesophageal reflux: a diagnostic approach. Dig Dis Sci. 1979 Nov; 24(11):839-44. PMID: 520103.
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    494. Castell D. How big is the normal liver, indeed! Arch Intern Med. 1979 Sep; 139(9):968-9. PMID: 475533.
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    495. Benjamin SB, Gerhardt DC, Castell DO. High amplitude, peristaltic esophageal contractions associated with chest pain and/or dysphagia. Gastroenterology. 1979 Sep; 77(3):478-83. PMID: 456842.
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    496. Dubois A, Gross HA, Ebert MH, Castell DO. Altered gastric emptying and secretion in primary anorexia nervosa. Gastroenterology. 1979 Aug; 77(2):319-23. PMID: 376392.
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    497. Bybee DE, Brown FC, Georges LP, Castell DO, McGuigan JE. Somatostatin effects on lower esophageal sphincter function. Am J Physiol. 1979 Jul; 237(1):E77-81. PMID: 111562.
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    498. Chernow B, Castell DO. Diet and heartburn. JAMA. 1979 May 25; 241(21):2307-8. PMID: 439304.
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    499. Castell DO, Knuff TE, Brown FC, Gerhardt DC, Burns TW, Gaskins RD. Clinical conference. Dysphagia. Gastroenterology. 1979 May; 76(5 Pt 1):1015-24. PMID: 437406.
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    500. Siegel SR, Brown FC, Castell DO, Johnson LF, Said SI. Effects of vasoactive intestinal polypeptide (VIP) on lower esophageal sphincter in awake baboons: comparison with glucagon and secretin. Dig Dis Sci. 1979 May; 24(5):345-9. PMID: 110570.
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    501. Castell DO. The spectrum of esophageal motility disorders. Gastroenterology. 1979 Mar; 76(3):639-40. PMID: 428717.
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    502. Chernow B, Castell DO. Nutritional balance in patients with malignant disease of the oral cavity. Otolaryngol Clin North Am. 1979 Feb; 12(1):161-6. PMID: 108649.
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    503. Dubois A, Price SF, Castell DO. Gastric retention in peptic ulcer disease. A reappraisal. Am J Dig Dis. 1978 Nov; 23(11):993-7. PMID: 717362.
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    504. Castell DO. Sense with cimetidine. JAMA. 1978 Aug 11; 240(6):564. PMID: 671673.
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    505. Price SF, Smithson KW, Castell DO. Food sensitivity in reflux esophagitis. Gastroenterology. 1978 Aug; 75(2):240-3. PMID: 27414.
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    506. Price CS, Castell DO. Esophageal mythology. JAMA. 1978 Jul 07; 240(1):44-6. PMID: 660810.
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    507. Brown FC, Gideon RM, Voelker FA, Castell DO. Muscle function and structure of the esophagus of the baboon (Papio anubis). Am J Vet Res. 1978 Jul; 39(7):1209-11. PMID: 98078.
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    508. Brown FC, Dubois A, Castell DO. Histaminergic pharmacology of primate lower esophageal sphincter. Am J Physiol. 1978 Jul; 235(1):E42-6. PMID: 98059.
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    509. Forman SA, Castell DO. Food intolerance and peptic ulcer disease. Gastroenterology. 1978 Jul; 75(1):162-3. PMID: 401088.
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    510. Castell DO. The aging esophagus. Am J Dig Dis. 1978 Jul; 23(7):667-8. PMID: 685932.
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    511. Castell DO. Lower esophageal sphincter hypotension or intragastric hypertension? Am J Dig Dis. 1978 Jul; 23(7):668-9. PMID: 685933.
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    512. Wen-Shung A, Lin M, Castell DO. Evidence of the importance of pH and salt concentration on column chromatography with Sepharose gel filtration in separation of proteins. Anal Biochem. 1978 Jun 01; 86(2):345-56. PMID: 26283.
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    513. Castell DO. Malnutrition in patients with malignant lesions of the head and neck. West J Med. 1978 Apr; 128(4):359. PMID: 18748199.
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    514. Humphries TJ, Higgs RH, Castell DO, Mcguigan JE. Serum gastrin concentrations following oral bethanechol with and without a meal. Am J Dig Dis. 1978 Mar; 23(3):225-8. PMID: 352137.
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    515. Behar J, Brand DL, Brown FC, Castell DO, Cohen S, Crossley RJ, Pope CE, Winans CS. Cimetidine in the treatment of symptomatic gastroesophageal reflux: a double blind controlled trial. Gastroenterology. 1978 Feb; 74(2 Pt 2):441-8. PMID: 340333.
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    516. Ludewig RM, Castell DO. Correlation between xenon-133 rectum-to-heart time and portal venous hemodynamics. J Surg Res. 1978 Feb; 24(2):92-6. PMID: 625107.
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    517. Castell DO. Gastrin and lower esophageal sphincter tone. Arch Intern Med. 1978 Feb; 138(2):196. PMID: 626547.
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    518. Castell DO. Medical measures that influence the gastroesophageal junction. South Med J. 1978 Jan; 71 Suppl 1:26-8. PMID: 24274.
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    519. Castell DO, Frank BB. Abdominal examination: role of percussion and auscultation. Postgrad Med. 1977 Dec; 62(6):131-4. PMID: 928243.
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    520. Hollis JB, Castell DO, Braddom RL. Esophageal function in diabetes mellitus and its relation to peripheral neuropathy. Gastroenterology. 1977 Nov; 73(5):1098-1102. PMID: 198334.
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    521. Humphries TJ, Castell DO. Pressure profile of esophageal peristalsis in normal humans as measured by direct intraesophageal transducers. Am J Dig Dis. 1977 Jul; 22(7):641-5. PMID: 879131.
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    522. Braddom RL, Hollis JB, Castell DO. Diabetic peripheral neuropathy: a correlation of nerve conduction studies and clinical findings. Arch Phys Med Rehabil. 1977 Jul; 58(7):308-13. PMID: 880006.
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    523. Chernow B, Castell DO. Asthma and gastroesophageal reflux. JAMA. 1977 May 30; 237(22):2379. PMID: 576934.
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    524. Brown FC, Johnson RB, Castell DO. Gastric perforation during pneumatic dilation for achalasia. Gastroenterology. 1977 May; 72(5 Pt 1):983-4. PMID: 849827.
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    525. Freeland GR, Higgs RH, Castell DO. Lower esophageal sphincter response to oral administration of cimetidine in normal subjects. Gastroenterology. 1977 Jan; 72(1):28-30. PMID: 11144.
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    526. Higgs RH, Castell DO. The effect of truncal vagotomy on lower esophageal sphincter pressure and response to cholinergic stimulation. Proc Soc Exp Biol Med. 1976 Dec; 153(3):379-82. PMID: 1013146.
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    527. Nebel OT, Fornes MF, Castell DO. Symptomatic gastroesophageal reflux: incidence and precipitating factors. Am J Dig Dis. 1976 Nov; 21(11):953-6. PMID: 984016.
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    528. Higgs RH, Humphries TJ, Castell DO, McGuigan JE. Lower esophageal sphincter pressures and serum gastrin levels after cholinergic stimulation. Am J Physiol. 1976 Oct; 231(4):1250-3. PMID: 984209.
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    529. Freeland GR, Higgs RH, Castell DO, McGuigan JE. Lower esophageal sphincter and gastric acid response to intravenous infusions of synthetic human gastrin I heptadecapeptide. Gastroenterology. 1976 Oct; 71(4):570-4. PMID: 955342.
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    530. Higgs RH, Castell DO, Eastwood GL. Studies on the mechanism of esophagitis-induced lower esophageal sphincter hypotension in cats. Gastroenterology. 1976 Jul; 71(1):51-6. PMID: 1278649.
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    531. Castell DO. Letter: Quantitation of gastroesophageal reflux. Gastroenterology. 1976 Jul; 71(1):179-80. PMID: 1278643.
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    532. Castell DO. Achalasia and diffuse esophageal spasm. Arch Intern Med. 1976 May; 136(5):571-9. PMID: 773328.
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    533. Ma Lin AW, Davis LM, Castell DO. Isoenzyme composition of human plasma monoamine oxidase in normal subjects and in fibrotic liver disease. Proc Soc Exp Biol Med. 1976 Jan; 151(1):40-3. PMID: 1250854.
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    534. Hollis JB, Castell DO. Effects of cholinergic stimulation on human esophageal peristalsis. J Appl Physiol. 1976 Jan; 40(1):40-3. PMID: 1248980.
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    535. Castell DO. Letter: LES pressure. Am J Dig Dis. 1975 Nov; 20(11):1095-6. PMID: 1200004.
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    536. Castell DO. Diet and the lower esophageal sphincter. Am J Clin Nutr. 1975 Nov; 28(11):1296-8. PMID: 1190108.
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    537. Higgs RH, Castell DO, Farrell RL. Evaluation of the effect of fundoplication on the incompetent lower esophageal sphincter. Surg Gynecol Obstet. 1975 Oct; 141(4):571-5. PMID: 1166384.
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    538. Castell DO. Physiology and pathophysiology of the lower esophageal sphincter. Ann Otol Rhinol Laryngol. 1975 Sep-Oct; 84(5 Pt 1):569-75. PMID: 1190666.
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    539. Castell DO. The lower esophageal sphincter. Physiologic and clinical aspects. Ann Intern Med. 1975 Sep; 83(3):390-401. PMID: 1236715.
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    540. Wright LE, Castell DO. The adverse effect of chocolate on lower esophageal sphincter pressure. Am J Dig Dis. 1975 Aug; 20(8):703-7. PMID: 239592.
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    541. Eastwood GL, Castell DO, Higgs RH. Experimental esophagitis in cats impairs lower esophageal sphincter pressure. Gastroenterology. 1975 Jul; 69(1):146-53. PMID: 1150019.
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    542. Lin AW, Castell DO. Multiple forms of monoamine oxidase in human plasma. Biochem Med. 1975 Jun; 13(2):141-56. PMID: 1191272.
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    543. Hollis JB, Castell DO. Effect of dry swallows and wet swallows of different volumes on esophageal peristalsis. J Appl Physiol. 1975 Jun; 38(6):1161-4. PMID: 1141133.
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    544. Higgs RH, Castell DO. Cholinergic stimulation of the lower esophageal sphincter in patients with vagotomy and antrectomy. Am J Dig Dis. 1975 Mar; 20(3):195-200. PMID: 1124744.
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    545. Nebel OT, Fornes MF, Macionus RF, Castell DO. Duodenoscopy in the diagnosis of upper gastrointestinal bleeding. Mil Med. 1975 Feb; 140(2):110-3. PMID: 803653.
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    546. Nebel OT, el-Masry NA, Castell DO, Farid Z, Fornes MF, Sparks HA. Schistosomal disease of the colon: a reversible form of polyposis. Gastroenterology. 1974 Nov; 67(5):939-43. PMID: 4426495.
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    547. Higgs RH, Smyth RD, Castell DO. Gastric alkalinization. Effect on lower-esophageal-sphincter pressure and serum gastrin. N Engl J Med. 1974 Sep 05; 291(10):486-90. PMID: 4852129.
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    548. Castell DO. Editorial: Acid perfusion revisited. Am J Dig Dis. 1974 Sep; 19(9):874-5. PMID: 4851486.
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    549. Farrell RL, Castell DO, McGuigan JE. Measurements and comparisons of lower esophageal sphincter pressures and serum gastrin levels in patients with gastroesophageal reflux. Gastroenterology. 1974 Sep; 67(3):415-22. PMID: 4853121.
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    550. Farrell RL, Roling GT, Castell DO. Cholinergic therapy of chronic heartburn. A controlled trial. Ann Intern Med. 1974 May; 80(5):573-6. PMID: 4596046.
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    551. Lin AW, Castell DO. Comparative studies on human plasma monoamine oxidase in normal subjects and in fibrotic liver disease. Biochem Med. 1974 Apr; 9(4):373-85. PMID: 4832206.
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    552. Hollis JB, Castell DO. Esophageal function in elderly man. A new look at "presbyesophagus". Ann Intern Med. 1974 Mar; 80(3):371-4. PMID: 4816179.
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    553. Nebel OT, el-Masry NA, Castell DO, Farid Z, Fornes MF, Sparks HA. Schistosomal colonic polyposis: endoscopic and histologic characteristics. Gastrointest Endosc. 1974 Feb; 20(3):99-101. PMID: 4815036.
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    554. Castell DO, Farrell RL. Letter: Weak gut sphincters in pernicious anemia. N Engl J Med. 1973 Nov 22; 289(21):1146-7. PMID: 4754955.
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    555. Farrell RL, Nebel OT, McGuire AT, Castell DO. The abnormal lower oesophageal sphincter in pernicious anaemia. Gut. 1973 Oct; 14(10):767-72. PMID: 4758657.
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    556. Farrell RL, Roling GT, Castell DO. Stimulation of the incompetent lower esophageal sphincter. A possible advance in therapy of heartburn. Am J Dig Dis. 1973 Aug; 18(8):646-50. PMID: 4721126.
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    557. Nebel OT, Castell DO. Kinetics of fat inhibition of the lower esophageal sphincter. J Appl Physiol. 1973 Jul; 35(1):6-8. PMID: 4716164.
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    558. Babka JC, Castell DO. On the genesis of heartburn. The effects of specific foods on the lower esophageal sphincter. Am J Dig Dis. 1973 May; 18(5):391-7. PMID: 4739809.
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    559. Babka JC, Hager GW, Castell DO. The effect of body position on lower esophageal sphincter pressure. Am J Dig Dis. 1973 May; 18(5):441-2. PMID: 4701043.
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    560. Nebel OT, Castell DO. Inhibition of the lower oesophageal sphincter by fat--a mechanism for fatty food intolerance. Gut. 1973 Apr; 14(4):270-4. PMID: 4706907.
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    561. Dennish GW, Castell DO. Caffeine and the lower esophageal sphincter. Am J Dig Dis. 1972 Nov; 17(11):993-6. PMID: 5082433.
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    562. Nebel OT, Castell DO. Lower esophageal sphincter pressure changes after food ingestion. Gastroenterology. 1972 Nov; 63(5):778-83. PMID: 5079488.
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    563. Hollis JB, Castell DO. Amplitude of esophageal peristalsis as determined by rapid infusion. Gastroenterology. 1972 Sep; 63(3):417-22. PMID: 5071282.
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    564. Castell DO, Conn HO. The determination of portacaval shunt patency: a critical review of methodology. Medicine (Baltimore). 1972 Jul; 51(4):315-36. PMID: 4537518.
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    565. Roling GT, Farrell RL, Castell DO. Cholinergic response of the lower esophageal sphincter. Am J Physiol. 1972 Apr; 222(4):967-72. PMID: 5027107.
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    566. Hollis JB, Levine SM, Castell DO. Differential sensitivity of the human esophagus to pentagastrin. Am J Physiol. 1972 Apr; 222(4):870-4. PMID: 5027095.
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    567. Cirillo NB, Castell DO, Jacoby WJ. Gastric acid secretion in infectious hepatitis. Mil Med. 1972 Feb; 137(2):64-6. PMID: 4621913.
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    568. Roling GT, Burke EL, Castell DO, Egleston TA. The esophago-gastric junction as evaluated by gastroscopy, esophageal manometry, and roentgenography. Gastrointest Endosc. 1971 Nov; 18(2):63-5. PMID: 5129976.
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    569. Castell DO. Changes in lower esophageal sphincter pressure during insulin-induced hypoglycemia. Gastroenterology. 1971 Jul; 61(1):10-5. PMID: 5088521.
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    570. Dennish GW, Castell DO. Inhibitory effect of smoking on the lower esophageal sphincter. N Engl J Med. 1971 May 20; 284(20):1136-7. PMID: 5553487.
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    571. Strickland GT, Castell DO, Kronmal RA. Prolonged observations on the liver function tests in infectious hepatitis. Am J Gastroenterol. 1971 Mar; 55(3):257-64. PMID: 5578089.
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    572. Castell DO, Levine SM. Lower esophageal sphincter response to gastric alkalinization. A new mechanism for treatment of heartburn with antacids. Ann Intern Med. 1971 Feb; 74(2):223-7. PMID: 5545230.
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    573. Castell DO, Moore EW. Ammonia absorption from the human colon. The role of nonionic diffusion. Gastroenterology. 1971 Jan; 60(1):33-42. PMID: 5101396.
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    574. Castell DO, Cohen S, Harris LD. Response of human ileocecal sphincter to gastrin. Am J Physiol. 1970 Sep; 219(3):712-5. PMID: 5450876.
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    575. Castell DO, Harris LD. Hormonal control of gastroesophageal-sphincter strength. N Engl J Med. 1970 Apr 16; 282(16):886-9. PMID: 5434934.
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    576. Castell DO, Grace ND, Wennar MH, Chalmers TC, Moore EW. Evaluation of portal circulation in hepatic cirrhosis. A new method using xenon. Gastroenterology. 1969 Nov; 57(5):533-41. PMID: 5348088.
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    577. Castell DO. Percussion of the liver. Ann Intern Med. 1969 Oct; 71(4):868. PMID: 5360296.
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    578. Linscheer WG, Castell DO, Platt RR. A new method for evaluation of portasystemic shunting. The rectal octanoate tolerance test. Gastroenterology. 1969 Oct; 57(4):415-23. PMID: 5212384.
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    579. Grace ND, Castell DO, Wennar MH. A comparison of the oral fructose and ammonia tolerance tests in cirrhosis. Arch Intern Med. 1969 Sep; 124(3):330-5. PMID: 5812417.
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    580. Castell DO, O'Brien KD, Muench H, Chalmers TC. Eastimation of liver size by percussion in normal individuals. Ann Intern Med. 1969 Jun; 70(6):1183-9. PMID: 5795743.
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    581. Johnson RB, Castell DO, Lukash WM. Liver scanning for detection of collateral circulation in liver disease. A survey of 567 hepatic photoscans. JAMA. 1969 Jan 20; 207(3):528-32. PMID: 5818215.
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    582. Conger JD, Castell DO, Jacoby WJ. Hodgkin's disease of the jejunum. Perforation during radiation therapy. Arch Intern Med. 1968 Feb; 121(2):174-6. PMID: 5636061.
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    583. Castell DO. The spleen percussion sign. A useful diagnostic technique. Ann Intern Med. 1967 Dec; 67(6):1265-7. PMID: 6061941.
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    584. Castell DO, Jacoby WJ. Gastrectasia of unknown etiology. A case report. Am J Gastroenterol. 1967 Oct; 48(4):343-8. PMID: 6075363.
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    585. Castell DO. Ascites in cirrhosis. Relative importance of portal hypertension and hypoalbuminemia. Am J Dig Dis. 1967 Sep; 12(9):916-22. PMID: 6039572.
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    586. McEwen CM, Castell DO. Abnormalities of serum monoamine oxidase in chronic liver disease. J Lab Clin Med. 1967 Jul; 70(1):36-47. PMID: 6027096.
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    587. Castell DO, Johnson RB, Sparks HA. Abbreviated Histalog gastric analysis. Comparison with peak acid output. Am J Dig Dis. 1967 Jul; 12(7):713-9. PMID: 6027595.
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    588. Castell DO, Sode J. Meprobamate intoxication treated with peritoneal dialysis. IMJ Ill Med J. 1967 Mar; 131(3):298-9. PMID: 4382659.
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    589. Castell DO, Sparks HA, Johnson RB. The importance of fluoroscopic tube placement during gastric analysis. Am J Dig Dis. 1967 Jan; 12(1):26-9. PMID: 6017990.
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    590. Castell DO. Evaluation of the hypertensive patient. GP. 1966 Nov; 34(5):109-12. PMID: 5917005.
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    591. Cohn R, Castell DO. The effect of acute hyperammoniemia on the electroencephalogram. J Lab Clin Med. 1966 Aug; 68(2):195-205. PMID: 5912595.
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    592. Castell DO, Johnson RB. The 198-Au liver scan. An index of portal-systemic collateral circulation in chronic liver disease. N Engl J Med. 1966 Jul 28; 275(4):188-92. PMID: 5938867.
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    593. Sode J, Zimmerman JE, Castell DO, Powell MR. Some unusual aspects of pheochromocytoma. Report of four cases. Med Ann Dist Columbia. 1966 Jun; 35(6):310-5. PMID: 5219901.
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    594. Castell DO. The ammonia tolerance test: an index of portal hypertension. Gastroenterology. 1965 Nov; 49(5):539-43. PMID: 5853161.
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    595. SCHMIDT E, CASTELL D, BROWN P. A RETROSPECTIVE STUDY OF 42 CASES OF BEHAVIOUR THERAPY. Behav Res Ther. 1965 Aug; 3:9-19. PMID: 14340598.
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    596. CASTELL DO. RENOVASCULAR HYPERTENSION: A THERAPEUTIC DILEMMA. GP. 1965 Aug; 32:118-23. PMID: 14334859.
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    597. CASTELL DO, SPARKS HA. NEPHROGENIC DIABETES INSIPIDUS DUE TO DEMETHYLCHLORTETRACYCLINE HYDROCHLORIDE. JAMA. 1965 Jul 19; 193:237-9. PMID: 14310339.
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    598. CASTELL DO. AMMONIA LOADS. N Engl J Med. 1965 Jan 14; 272:105-6. PMID: 14223120.
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    599. WARRENDER WF, CASTELL DO, KARLSBERG RC. RENOVASCULAR HYPERTENSION. Med Ann Dist Columbia. 1964 Oct; 33:481-6. PMID: 14198507.
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    600. THORPE JG, SCHMIDT E, BROWN PT, CASTELL D. AVERSION-RELIEF THERAPY: A NEW METHOD FOR GENERAL APPLICATION. Behav Res Ther. 1964 May; 2:71-82. PMID: 14170312.
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