David Michael Neskey

Title
InstitutionMedical University of South Carolina
DepartmentOtolaryngology - Head and Neck Surgery
AddressP.O. Box MSC 550
1130
Rutledge Tower Building - 135 Rutledge Ave.
Phone843-792-8299
Fax843-792-0546
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    Cancer/Head & Neck

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Graboyes EM, Sterba KR, Li H, Warren GW, Alberg AJ, Calhoun EA, Nussenbaum B, McCay J, Marsh CH, Osazuwa-Peters N, Neskey DM, Kaczmar JM, Sharma AK, Harper J, Day TA, Hughes-Halbert C. Development and Evaluation of a Navigation-Based, Multilevel Intervention to Improve the Delivery of Timely, Guideline-Adherent Adjuvant Therapy for Patients With Head and Neck Cancer. JCO Oncol Pract. 2021 Mar 10; OP2000943. PMID: 33689399.
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    2. Yan F, Li H, de Almeida JR, Kaczmar JM, Pipkorn P, Zenga J, Richardson MS, Neskey DM, Sharma AK, Day TA, Graboyes EM. Microscopic Extranodal Extension in HPV-Negative Head and Neck Cancer and the Role of Adjuvant Chemoradiation. Otolaryngol Head Neck Surg. 2021 Feb 23; 194599821989637. PMID: 33618570.
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    3. Yan F, Li H, Kaczmar JM, Sharma AK, Day TA, Neskey DM, Pipkorn P, Zenga J, Graboyes EM. Evaluating Adjuvant Therapy With Chemoradiation vs Radiation Alone for Patients With HPV-Negative N2a Head and Neck Cancer. JAMA Otolaryngol Head Neck Surg. 2020 12 01; 146(12):1109-1119. PMID: 32790830.
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    4. Graboyes EM, Halbert CH, Li H, Warren GW, Alberg AJ, Calhoun EA, Nussenbaum B, Marsh CH, McCay J, Day TA, Kaczmar JM, Sharma AK, Neskey DM, Sterba KR. Barriers to the Delivery of Timely, Guideline-Adherent Adjuvant Therapy Among Patients With Head and Neck Cancer. JCO Oncol Pract. 2020 12; 16(12):e1417-e1432. PMID: 32853120.
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    5. Gleber-Netto FO, Neskey D, Costa AFM, Kataria P, Rao X, Wang J, Kowalski LP, Pickering CR, Dias-Neto E, Myers JN. Functionally impactful TP53 mutations are associated with increased risk of extranodal extension in clinically advanced oral squamous cell carcinoma. Cancer. 2020 10 15; 126(20):4498-4510. PMID: 32797678.
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    6. Yan F, Knochelmann HM, Morgan PF, Kaczmar JM, Neskey DM, Graboyes EM, Nguyen SA, Ogretmen B, Sharma AK, Day TA. The Evolution of Care of Cancers of the Head and Neck Region: State of the Science in 2020. Cancers (Basel). 2020 Jun 11; 12(6). PMID: 32545409.
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    7. Dwyer CJ, Arhontoulis DC, Rangel Rivera GO, Knochelmann HM, Smith AS, Wyatt MM, Rubinstein MP, Atkinson C, Thaxton JE, Neskey DM, Paulos CM. Ex vivo blockade of PI3K gamma or delta signaling enhances the antitumor potency of adoptively transferred CD8+ T cells. Eur J Immunol. 2020 09; 50(9):1386-1399. PMID: 32383488.
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    8. Gupta A, Koochakzadeh S, Neskey DM, Nguyen SA, Lentsch EJ. Incidence and survival trends of parotid malignancies over 42?years. Head Neck. 2020 09; 42(9):2308-2315. PMID: 32314846.
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    9. Xiong Y, Neskey DM, Horton JD, Paulos CM, Knochelmann HM, Armeson KE, Young MRI. Immunological effects of nivolumab immunotherapy in patients with oral cavity squamous cell carcinoma. BMC Cancer. 2020 Mar 17; 20(1):229. PMID: 32183719.
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    10. Graboyes EM, Hill EG, Marsh CH, Maurer S, Day TA, Hornig JD, Lentsch EJ, Neskey DM, Skoner J, Sterba KR. Temporal Trajectory of Body Image Disturbance in Patients with Surgically Treated Head and Neck Cancer. Otolaryngol Head Neck Surg. 2020 03; 162(3):304-312. PMID: 31906788.
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    11. Gupta A, Koochakzadeh S, Neskey DM, Nguyen SA, Lentsch EJ. Carcinoma ex pleomorphic adenoma: A review of incidence, demographics, risk factors, and survival. Am J Otolaryngol. 2019 Nov - Dec; 40(6):102279. PMID: 31471126.
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    12. Gupta A, Koochakzadeh S, Neskey DM, Nguyen SA, Lentsch EJ. Salivary Carcinosarcoma: An Extremely Rare and Highly Aggressive Malignancy. Laryngoscope. 2020 05; 130(5):E335-E339. PMID: 31291005.
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    13. Horton JD, Knochelmann HM, Day TA, Paulos CM, Neskey DM. Immune Evasion by Head and Neck Cancer: Foundations for Combination Therapy. Trends Cancer. 2019 04; 5(4):208-232. PMID: 30961829.
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    14. Graboyes EM, Kompelli AR, Neskey DM, Brennan E, Nguyen S, Sterba KR, Warren GW, Hughes-Halbert C, Nussenbaum B, Day TA. Association of Treatment Delays With Survival for Patients With Head and Neck Cancer: A Systematic Review. JAMA Otolaryngol Head Neck Surg. 2019 02 01; 145(2):166-177. PMID: 30383146.
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    15. Kompelli AR, Morgan P, Li H, Harris W, Day TA, Neskey DM. Prognostic Impact of High-Risk Pathologic Features in HPV-Related Oropharyngeal Squamous Cell Carcinoma and Tobacco Use. Otolaryngol Head Neck Surg. 2019 05; 160(5):855-861. PMID: 30526292.
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    16. Kompelli AR, Li H, Neskey DM. Impact of Delay in Treatment Initiation on Overall Survival in Laryngeal Cancers. Otolaryngol Head Neck Surg. 2019 04; 160(4):651-657. PMID: 30322343.
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    17. Semelakova M, Grauzam S, Betadthunga P, Tiedeken J, Coaxum S, Neskey DM, Rosenzweig SA. Vimentin and Non-Muscle Myosin IIA are Members of the Neural Precursor Cell Expressed Developmentally Down-Regulated 9 (NEDD9) Interactome in Head and Neck Squamous Cell Carcinoma Cells. Transl Oncol. 2019 Jan; 12(1):49-61. PMID: 30267961.
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    18. Kompelli AR, Ni JS, Nguyen SA, Lentsch EJ, Neskey DM, Meyer TA. The outcomes of hypoglossal nerve stimulation in the management of OSA: A systematic review and meta-analysis. World J Otorhinolaryngol Head Neck Surg. 2019 Mar; 5(1):41-48. PMID: 30775701.
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    19. Fabie JE, Hatch JL, Cross AW, Oyer SL, Neskey DM, McRackan TR. Metastatic Salivary Ductal Carcinoma to the Mastoid Segment of the Facial Nerve. Otol Neurotol. 2018 09; 39(8):e722-e725. PMID: 30063500.
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    20. Janz TA, Graboyes EM, Nguyen SA, Ellis MA, Neskey DM, Harruff EE, Lentsch EJ. A Comparison of the NCDB and SEER Database for Research Involving Head and Neck Cancer. Otolaryngol Head Neck Surg. 2019 02; 160(2):284-294. PMID: 30129822.
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    21. Janz TA, Neskey DM, Nguyen SA, Lentsch EJ. Is the incidence of anaplastic thyroid cancer increasing: A population based epidemiology study. World J Otorhinolaryngol Head Neck Surg. 2019 Mar; 5(1):34-40. PMID: 30775700.
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    22. Janz TA, Neskey DM, Nguyen SA, Lentsch EJ. Is imaging of the brain necessary at diagnosis for cutaneous head and neck melanomas? Am J Otolaryngol. 2018 Sep - Oct; 39(5):631-635. PMID: 29929862.
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    23. Grauzam S, Brock AM, Holmes CO, Tiedeken JA, Boniface SG, Pierson BN, Patterson DG, Coaxum SD, Neskey DM, Rosenzweig SA. NEDD9 stimulated MMP9 secretion is required for invadopodia formation in oral squamous cell carcinoma. Oncotarget. 2018 May 22; 9(39):25503-25516. PMID: 29876004.
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    24. Zhan KY, Morgan PF, Neskey DM, Kim JJ, Huang AT, Garrett-Mayer E, Day TA. Preoperative predictors of occult nodal disease in cT1N0 oral cavity squamous cell carcinoma: Review of 2623 cases. Head Neck. 2018 09; 40(9):1967-1976. PMID: 29761586.
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    25. Ellis MA, Graboyes EM, Wahlquist AE, Neskey DM, Kaczmar JM, Schopper HK, Sharma AK, Morgan PF, Nguyen SA, Day TA. Primary Surgery vs Radiotherapy for Early Stage Oral Cavity Cancer. Otolaryngol Head Neck Surg. 2018 04; 158(4):649-659. PMID: 29256326.
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    26. Borucki RB, Neskey DM, Lentsch EJ. Malignant fibrous histiocytoma: Database review suggests a favorable prognosis in the head and neck. Laryngoscope. 2018 04; 128(4):885-888. PMID: 28988458.
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    27. Ellis MA, Graboyes EM, Day TA, Neskey DM. Prognostic factors and occult nodal disease in mucoepidermoid carcinoma of the oral cavity and oropharynx: An analysis of the National Cancer Database. Oral Oncol. 2017 09; 72:174-178. PMID: 28797455.
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    28. Lohia S, Momin S, Richardson MS, Neskey D. Intravascular Papillary Endothelial Hyperplasia of the Neck: A Case Report. OTO Open. 2017 Apr-Jun; 1(2):2473974X17699795. PMID: 30480181.
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    29. Coaxum SD, Tiedeken J, Garrett-Mayer E, Myers J, Rosenzweig SA, Neskey DM. The tumor suppressor capability of p53 is dependent on non-muscle myosin IIA function in head and neck cancer. Oncotarget. 2017 Apr 04; 8(14):22991-23007. PMID: 28160562.
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    30. Ellis MA, Gerry DR, Neskey DM, Lentsch EJ. Ewing Sarcoma of the Head and Neck. Ann Otol Rhinol Laryngol. 2017 Mar; 126(3):179-184. PMID: 28056517.
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    31. Majumder M, House R, Palanisamy N, Qie S, Day TA, Neskey D, Diehl JA, Palanisamy V. Correction: RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC. PLoS Genet. 2016 Oct; 12(10):e1006411. PMID: 27783624.
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    32. Majumder M, House R, Palanisamy N, Qie S, Day TA, Neskey D, Diehl JA, Palanisamy V. RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC. PLoS Genet. 2016 09; 12(9):e1006306. PMID: 27606879.
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    33. Osman AA, Neskey DM, Katsonis P, Patel AA, Ward AM, Hsu TK, Hicks SC, McDonald TO, Ow TJ, Alves MO, Pickering CR, Skinner HD, Zhao M, Sturgis EM, Kies MS, El-Naggar A, Perrone F, Licitra L, Bossi P, Kimmel M, Frederick MJ, Lichtarge O, Myers JN. Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients. Cancer Res. 2015 Apr 01; 75(7):1205-15. PMID: 25691460.
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    34. Neskey DM, Osman AA, Ow TJ, Katsonis P, McDonald T, Hicks SC, Hsu TK, Pickering CR, Ward A, Patel A, Yordy JS, Skinner HD, Giri U, Sano D, Story MD, Beadle BM, El-Naggar AK, Kies MS, William WN, Caulin C, Frederick M, Kimmel M, Myers JN, Lichtarge O. Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer. Cancer Res. 2015 Apr 01; 75(7):1527-36. PMID: 25634208.
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    35. Osman AA, Monroe MM, Ortega Alves MV, Patel AA, Katsonis P, Fitzgerald AL, Neskey DM, Frederick MJ, Woo SH, Caulin C, Hsu TK, McDonald TO, Kimmel M, Meyn RE, Lichtarge O, Myers JN. Wee-1 kinase inhibition overcomes cisplatin resistance associated with high-risk TP53 mutations in head and neck cancer through mitotic arrest followed by senescence. . 2015 Feb; 14(2):608-19. PMID: 25504633.
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    36. Pickering CR, Zhang J, Neskey DM, Zhao M, Jasser SA, Wang J, Ward A, Tsai CJ, Ortega Alves MV, Zhou JH, Drummond J, El-Naggar AK, Gibbs R, Weinstein JN, Wheeler DA, Wang J, Frederick MJ, Myers JN. Squamous cell carcinoma of the oral tongue in young non-smokers is genomically similar to tumors in older smokers. Clin Cancer Res. 2014 Jul 15; 20(14):3842-8. PMID: 24874835.
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    37. Neskey DM, Klein JD, Hicks S, Garden AS, Bell DM, El-Naggar AK, Kies MS, Weber RS, Kupferman ME. Prognostic factors associated with decreased survival in patients with acinic cell carcinoma. JAMA Otolaryngol Head Neck Surg. 2013 Nov; 139(11):1195-202. PMID: 24076756.
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    38. Gadhikar MA, Sciuto MR, Alves MV, Pickering CR, Osman AA, Neskey DM, Zhao M, Fitzgerald AL, Myers JN, Frederick MJ. Chk1/2 inhibition overcomes the cisplatin resistance of head and neck cancer cells secondary to the loss of functional p53. . 2013 Sep; 12(9):1860-73. PMID: 23839309.
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    39. Yang CZ, Ma J, Luo QQ, Neskey DM, Zhu DW, Liu Y, Myers JN, Zhang CP, Zhang ZY, Zhong LP. Elevated level of serum growth differentiation factor 15 is associated with oral leukoplakia and oral squamous cell carcinoma. J Oral Pathol Med. 2014 Jan; 43(1):28-34. PMID: 23710769.
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    40. Pickering CR, Zhang J, Yoo SY, Bengtsson L, Moorthy S, Neskey DM, Zhao M, Ortega Alves MV, Chang K, Drummond J, Cortez E, Xie TX, Zhang D, Chung W, Issa JP, Zweidler-McKay PA, Wu X, El-Naggar AK, Weinstein JN, Wang J, Muzny DM, Gibbs RA, Wheeler DA, Myers JN, Frederick MJ. Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers. Cancer Discov. 2013 Jul; 3(7):770-81. PMID: 23619168.
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    41. Perez A, Neskey DM, Wen J, Pereira L, Reategui EP, Goodwin WJ, Carraway KL, Franzmann EJ. CD44 interacts with EGFR and promotes head and neck squamous cell carcinoma initiation and progression. Oral Oncol. 2013 Apr; 49(4):306-13. PMID: 23265944.
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    42. Eloy JA, Neskey DM, Vivero RJ, Ruiz JW, Choudhry OJ, Casiano RR. High-resolution computed tomography analysis of the frontal sinus ostium: a pilot study. Am J Otolaryngol. 2013 Mar-Apr; 34(2):99-102. PMID: 23102967.
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    43. Ma J, Liu Y, Huang XL, Zhang ZY, Myers JN, Neskey DM, Zhong LP. Induction chemotherapy decreases the rate of distant metastasis in patients with head and neck squamous cell carcinoma but does not improve survival or locoregional control: a meta-analysis. Oral Oncol. 2012 Nov; 48(11):1076-84. PMID: 22800881.
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    44. Neskey DM, Hatoum G, Modh R, Civantos F, Telischi FF, Angeli SI, Weed D, Sargi Z. Outcomes after surgical resection of head and neck paragangliomas: a review of 61 patients. Skull Base. 2011 May; 21(3):171-6. PMID: 22451821.
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    45. Lee SL, Neskey D, Mouzakes J. Potential predisposition for nasal septal perforation with methotrexate use: report of 2 cases and literature review. Ear Nose Throat J. 2009 Aug; 88(8):E12-4. PMID: 19688702.
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    46. Neskey D, Eloy JA, Casiano RR. Nasal, septal, and turbinate anatomy and embryology. Otolaryngol Clin North Am. 2009 Apr; 42(2):193-205, vii. PMID: 19328886.
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    47. Neskey DM, Ambesi A, Pumiglia KM, McKeown-Longo PJ. Endostatin and anastellin inhibit distinct aspects of the angiogenic process. J Exp Clin Cancer Res. 2008 Nov 04; 27:61. PMID: 18983664.
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    48. Gross KL, Neskey DM, Manchanda N, Weremowicz S, Kleinman MS, Nowak RA, Ligon AH, Rogalla P, Drechsler K, Bullerdiek J, Morton CC. HMGA2 expression in uterine leiomyomata and myometrium: quantitative analysis and tissue culture studies. Genes Chromosomes Cancer. 2003 Sep; 38(1):68-79. PMID: 12874787.
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    49. Quade BJ, Weremowicz S, Neskey DM, Vanni R, Ladd C, Dal Cin P, Morton CC. Fusion transcripts involving HMGA2 are not a common molecular mechanism in uterine leiomyomata with rearrangements in 12q15. Cancer Res. 2003 Mar 15; 63(6):1351-8. PMID: 12649198.
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    50. Dal Cin P, Quade BJ, Neskey DM, Kleinman MS, Weremowicz S, Morton CC. Intravenous leiomyomatosis is characterized by a der(14)t(12;14)(q15;q24). Genes Chromosomes Cancer. 2003 Feb; 36(2):205-6. PMID: 12508249.
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