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David J. Cole

TitlePresident, Medical University of South Carolina
InstitutionMedical University of South Carolina
DepartmentGeneral Surgery
AddressP.O. Box MSC 001
Colcock Hall - 179 Ashley Ave.
Phone843-792-2211
Fax843-792-8827
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    President David J. Cole, M.D., FACS came to the Medical University in 1994 as an Assistant Professor in the Department of Surgery, Division of General Surgery. He quickly rose through the ranks and was promoted to Professor in 2002. At the same time, Dr. Cole assumed the positions of Vice Chairman for the Department of Surgery and Chief of the Division of General Surgery. In 2003 Dr. Cole was named the A. McKoy Rose, Jr., M.D. Endowed Chair in Surgical Oncology and was selected as Chairman for the Department of Surgery in September of 2007. From 2011 to 2013 Dr. Cole served as Secretary for MUSC Physicians (known at the time as University Medical Associates) and was elected President of MUSC Physicians in 2013. He held these esteemed titles until becoming President of MUSC on July 1, 2014.

    Dr. Cole is board certified through the American Board of Surgery with primary clinical fields of interest in breast cancer and gastro-intestinal malignancies. Dr Cole has been recognized as one of the nation’s leading surgeons over the past decade.

    In addition to his clinical expertise, Dr. Cole brings a strong research background with more than 17 years of continuous funding by the National Institutes of Health (NIH). He recently stepped down after seven years as the Medical Director for the Center for Cellular Therapy in order to concentrate on the needs surrounding his newest role. His research at the Center focused on novel cancer vaccine development and molecular diagnostics. As a thought-leader and innovator, Dr. Cole served as principal investigator for numerous clinical trials through the years and has secured multiple patents. He served on numerous National Cancer Institute (NCI) review panels and study sections, and authored more than 110 peer-reviewed publications and chapters.

    As a member of numerous professional and scientific societies including the American Association for Cancer Research, American Surgical Society, Southern Surgical Association, AAMC Council of Academic Societies, Society of University Surgeons, Halsted Society, and International Society of Surgery, Dr. Cole held many leadership positions including his current role as president for the Southeastern Surgical Congress, the largest regional organization for general surgeons in the United States.

    A New Mexico native, Dr. Cole received his Bachelor of Science degree in Biology from New Mexico State University in Las Cruces where he graduated with highest honors and was a Rhodes Scholarship finalist. He received his medical degree from Cornell University Medical College in New York and was elected to Alpha Omega Alpha Honor Medical Society. He interned and completed his residency at Emory University Affiliated Hospitals in Atlanta and his fellowship in Surgical Oncology at the NIH/NCI Surgery Branch in Bethesda.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Lockett MA, Turley C, Gibbons L, Stinson S, Adams JL, Cole D, Baliga PK. The South Carolina Surgical Quality Collaborative: A New Effort to Improve Surgical Outcomes in South Carolina. Am Surg. 2018 Jun 01; 84(6):916-919. PMID: 29981624.
      View in: PubMed
    2. Johnson CB, May BR, Riesenberg BP, Suriano S, Mehrotra S, Garrett-Mayer E, Salem ML, Jeng EK, Wong HC, Paulos CM, Wrangle JM, Cole DJ, Rubinstein MP. Enhanced Lymphodepletion Is Insufficient to Replace Exogenous IL2 or IL15 Therapy in Augmenting the Efficacy of Adoptively Transferred Effector CD8+ T Cells. Cancer Res. 2018 06 01; 78(11):3067-3074. PMID: 29636345.
      View in: PubMed
    3. Wrangle JM, Patterson A, Johnson CB, Neitzke DJ, Mehrotra S, Denlinger CE, Paulos CM, Li Z, Cole DJ, Rubinstein MP. IL-2 and Beyond in Cancer Immunotherapy. J Interferon Cytokine Res. 2018 Feb; 38(2):45-68. PMID: 29443657.
      View in: PubMed
    4. Adland E, Hill M, Lavandier N, Csala A, Edwards A, Chen F, Radkowski M, Kowalska JD, Paraskevis D, Hatzakis A, Valenzuela-Ponce H, Pfafferott K, Williams I, Pellegrino P, Borrow P, Mori M, Rockstroh J, Prado JG, Mothe B, Dalmau J, Martinez-Picado J, Tudor-Williams G, Frater J, Stryhn A, Buus S, Teran GR, Mallal S, John M, Buchbinder S, Kirk G, Martin J, Michael N, Fellay J, Deeks S, Walker B, Avila-Rios S, Cole D, Brander C, Carrington M, Goulder P. Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection. J Virol. 2018 02 15; 92(4). PMID: 29167337.
      View in: PubMed
    5. Aleksic T, Verrill C, Bryant RJ, Han C, Worrall AR, Brureau L, Larré S, Higgins GS, Fazal F, Sabbagh A, Haider S, Buffa FM, Cole D, Macaulay VM. IGF-1R associates with adverse outcomes after radical radiotherapy for prostate cancer. Br J Cancer. 2017 Nov 21; 117(11):1600-1606. PMID: 28972962.
      View in: PubMed
    6. Mehrotra S, Britten CD, Chin S, Garrett-Mayer E, Cloud CA, Li M, Scurti G, Salem ML, Nelson MH, Thomas MB, Paulos CM, Salazar AM, Nishimura MI, Rubinstein MP, Li Z, Cole DJ. Vaccination with poly(IC:LC) and peptide-pulsed autologous dendritic cells in patients with pancreatic cancer. J Hematol Oncol. 2017 04 07; 10(1):82. PMID: 28388966.
      View in: PubMed
    7. Neitzke DJ, Bowers JS, Andrijauskaite K, O'Connell NS, Garrett-Mayer E, Wrangle J, Li Z, Paulos CM, Cole DJ, Rubinstein MP. Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis. Cancer Immunol Immunother. 2017 Jun; 66(6):737-751. PMID: 28280853.
      View in: PubMed
    8. Li G, Liu D, Cooper TK, Kimchi ET, Qi X, Avella DM, Li N, Yang QX, Kester M, Rountree CB, Kaifi JT, Cole DJ, Rockey DC, Schell TD, Staveley-O'Carroll KF. Successful chemoimmunotherapy against hepatocellular cancer in a novel murine model. J Hepatol. 2017 01; 66(1):75-85. PMID: 27520877.
      View in: PubMed
    9. Doedens AL, Rubinstein MP, Gross ET, Best JA, Craig DH, Baker MK, Cole DJ, Bui JD, Goldrath AW. Molecular Programming of Tumor-Infiltrating CD8+ T Cells and IL15 Resistance. Cancer Immunol Res. 2016 09 02; 4(9):799-811. PMID: 27485135.
      View in: PubMed
    10. Banerjee A, Thyagarajan K, Chatterjee S, Chakraborty P, Kesarwani P, Soloshchenko M, Al-Hommrani M, Andrijauskaite K, Moxley K, Janakiraman H, Scheffel MJ, Helke K, Armenson K, Palanisamy V, Rubinstein MP, Mayer EG, Cole DJ, Paulos CM. Lack of p53 Augments Antitumor Functions in Cytolytic T Cells. Cancer Res. 2016 09 15; 76(18):5229-5240. PMID: 27466285.
      View in: PubMed
    11. Salem ML, Nassef M, Abdel Salam SG, Zidan A, Mahmoud MH, Badr G, Rubinstein M, Cole D. Effect of administration timing of postchemotherapy granulocyte colony-stimulating factor on host-immune cell recovery and CD8+ T-cell response. J Immunotoxicol. 2016 11; 13(6):784-792. PMID: 27417188.
      View in: PubMed
    12. Cole DJ. Crossroads-2016 Southeastern Surgical Congress Presidential Address. Am Surg. 2016 Jul; 82(7):571-4. PMID: 27457853.
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    13. Girijavallabhan V, Arasappan A, Bennett F, Chen K, Dang Q, Huang Y, Kerekes A, Nair L, Pissarnitski D, Verma V, Alvarez C, Chen P, Cole D, Esposite S, Huang Y, Hong Q, Liu Z, Pan W, Pu H, Rossman R, Truong Q, Vibulbhan B, Wang J, Zhao Z, Olsen D, Stamford A, Bogen S, Njoroge FG. 2'-Modified Guanosine Analogs for the Treatment of HCV. Nucleosides Nucleotides Nucleic Acids. 2016 Jun 02; 35(6):277-94. PMID: 27104963.
      View in: PubMed
    14. Nash CJ, Cole DJ, Bigler RS. A review of human sensory dynamics for application to models of driver steering and speed control. Biol Cybern. 2016 06; 110(2-3):91-116. PMID: 27086133.
      View in: PubMed
    15. Johnson CB, Wrangle J, Mehrotra S, Li Z, Paulos CM, Cole DJ, Surh CD, Rubinstein MP. Harnessing the IL-7/IL-7Ra axis to improve tumor immunotherapy. Oncoimmunology. 2016 May; 5(5):e1122865. PMID: 27467935.
      View in: PubMed
    16. Little EC, Camp ER, Wang C, Watson PM, Watson DK, Cole DJ. The CaSm (LSm1) oncogene promotes transformation, chemoresistance and metastasis of pancreatic cancer cells. Oncogenesis. 2016 Jan 11; 5:e182. PMID: 26751936.
      View in: PubMed
    17. Su EW, Moore CJ, Suriano S, Johnson CB, Songalia N, Patterson A, Neitzke DJ, Andrijauskaite K, Garrett-Mayer E, Mehrotra S, Paulos CM, Doedens AL, Goldrath AW, Li Z, Cole DJ, Rubinstein MP. IL-2Ra mediates temporal regulation of IL-2 signaling and enhances immunotherapy. Sci Transl Med. 2015 Oct 28; 7(311):311ra170. PMID: 26511507.
      View in: PubMed
    18. Johnson CB, Riesenberg BP, May BR, Gilreath SC, Li G, Staveley-O'Carroll KF, Garrett-Mayer E, Mehrotra S, Cole DJ, Rubinstein MP. Effector CD8+ T-cell Engraftment and Antitumor Immunity in Lymphodepleted Hosts Is IL7Ra Dependent. Cancer Immunol Res. 2015 Dec; 3(12):1364-74. PMID: 26297711.
      View in: PubMed
    19. Wang J, Lu Z, Wang J, Cui M, Yeung BZ, Cole DJ, Wientjes MG, Au JL. Paclitaxel tumor priming promotes delivery and transfection of intravenous lipid-siRNA in pancreatic tumors. J Control Release. 2015 Oct 28; 216:103-10. PMID: 26272765.
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    20. Andrijauskaite K, Suriano S, Cloud CA, Li M, Kesarwani P, Stefanik LS, Moxley KM, Salem ML, Garrett-Mayer E, Paulos CM, Mehrotra S, Kochenderfer JN, Cole DJ, Rubinstein MP. IL-12 conditioning improves retrovirally mediated transduction efficiency of CD8+ T cells. Cancer Gene Ther. 2015 Jul; 22(7):360-7. PMID: 26182912.
      View in: PubMed
    21. Anderson BJ, Hill EG, Sweeney RE, Wahlquist AE, Marshall DT, Staveley O'Carroll KF, Cole DJ, Camp ER. The impact of surgical diversion before neoadjuvant therapy for rectal cancer. Am Surg. 2015 May; 81(5):444-9. PMID: 25975325.
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    22. Bowers JS, Nelson MH, Kundimi S, Bailey SR, Huff LW, Schwartz KM, Cole DJ, Rubinstein MP, Paulos CM. Dendritic Cells in Irradiated Mice Trigger the Functional Plasticity and Antitumor Activity of Adoptively Transferred Tc17 Cells via IL12 Signaling. Clin Cancer Res. 2015 Jun 01; 21(11):2546-57. PMID: 25904754.
      View in: PubMed
    23. Rubinstein MP, Su EW, Suriano S, Cloud CA, Andrijauskaite K, Kesarwani P, Schwartz KM, Williams KM, Johnson CB, Li M, Scurti GM, Salem ML, Paulos CM, Garrett-Mayer E, Mehrotra S, Cole DJ. Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8(+) T cells. Cancer Immunol Immunother. 2015 May; 64(5):539-49. PMID: 25676709.
      View in: PubMed
    24. Nelson MH, Kundimi S, Bowers JS, Rogers CE, Huff LW, Schwartz KM, Thyagarajan K, Little EC, Mehrotra S, Cole DJ, Rubinstein MP, Paulos CM. The inducible costimulator augments Tc17 cell responses to self and tumor tissue. J Immunol. 2015 Feb 15; 194(4):1737-47. PMID: 25576595.
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    25. Esnaola NF, Chaudhary UB, O'Brien P, Garrett-Mayer E, Camp ER, Thomas MB, Cole DJ, Montero AJ, Hoffman BJ, Romagnuolo J, Orwat KP, Marshall DT. Phase 2 trial of induction gemcitabine, oxaliplatin, and cetuximab followed by selective capecitabine-based chemoradiation in patients with borderline resectable or unresectable locally advanced pancreatic cancer. Int J Radiat Oncol Biol Phys. 2014 Mar 15; 88(4):837-44. PMID: 24606850.
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    26. Wang J, Lu Z, Yeung BZ, Wientjes MG, Cole DJ, Au JL. Tumor priming enhances siRNA delivery and transfection in intraperitoneal tumors. J Control Release. 2014 Mar 28; 178:79-85. PMID: 24462901.
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    27. Lu Z, Tsai M, Wang J, Cole DJ, Wientjes MG, Au JL. Activity of drug-loaded tumor-penetrating microparticles in peritoneal pancreatic tumors. Curr Cancer Drug Targets. 2014; 14(1):70-8. PMID: 24200079.
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    28. Morse MA, Niedzwiecki D, Marshall JL, Garrett C, Chang DZ, Aklilu M, Crocenzi TS, Cole DJ, Dessureault S, Hobeika AC, Osada T, Onaitis M, Clary BM, Hsu D, Devi GR, Bulusu A, Annechiarico RP, Chadaram V, Clay TM, Lyerly HK. A randomized phase II study of immunization with dendritic cells modified with poxvectors encoding CEA and MUC1 compared with the same poxvectors plus GM-CSF for resected metastatic colorectal cancer. Ann Surg. 2013 Dec; 258(6):879-86. PMID: 23657083.
      View in: PubMed
    29. Rubinstein MP, Salem ML, Doedens AL, Moore CJ, Chiuzan C, Rivell GL, Cole DJ, Goldrath AW. G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses. J Hematol Oncol. 2013 Oct 01; 6:75. PMID: 24279871.
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    30. Johannesmeyer D, Smith V, Cole DJ, Esnaola NF, Camp ER. The impact of lymph node disease in extremity soft-tissue sarcomas: a population-based analysis. Am J Surg. 2013 Sep; 206(3):289-95. PMID: 23806824.
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    31. Camp ER, Wang C, Little EC, Watson PM, Pirollo KF, Rait A, Cole DJ, Chang EH, Watson DK. Transferrin receptor targeting nanomedicine delivering wild-type p53 gene sensitizes pancreatic cancer to gemcitabine therapy. Cancer Gene Ther. 2013 Apr; 20(4):222-8. PMID: 23470564.
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    32. Mehrotra S, Al-Khami AA, Klarquist J, Husain S, Naga O, Eby JM, Murali AK, Lyons GE, Li M, Spivey ND, Norell H, Martins da Palma T, Onicescu G, Diaz-Montero CM, Garrett-Mayer E, Cole DJ, Le Poole IC, Nishimura MI. A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice. J Immunol. 2012 Aug 15; 189(4):1627-38. PMID: 22798675.
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    33. Cole DJ, Rubinstein MP. Soluble IL-15/IL-15Ra complexes in human serum. Blood. 2012 Jul 05; 120(1):1-2. PMID: 22767572.
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    34. Wright S, Armeson K, Hill EG, Streck C, Leddy L, Cole D, Esnaola N, Camp ER. The role of sentinel lymph node biopsy in select sarcoma patients: a meta-analysis. Am J Surg. 2012 Oct; 204(4):428-33. PMID: 22578407.
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    35. Salem ML, Al-Khami AA, El-Nagaar SA, Zidan AA, Al-Sharkawi IM, Marcela Díaz-Montero C, Cole DJ. Kinetics of rebounding of lymphoid and myeloid cells in mouse peripheral blood, spleen and bone marrow after treatment with cyclophosphamide. Cell Immunol. 2012 Mar-Apr; 276(1-2):67-74. PMID: 22560674.
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    36. Kohlhapp FJ, Zloza A, O'Sullivan JA, Moore TV, Lacek AT, Jagoda MC, McCracken J, Cole DJ, Guevara-Patiño JA. CD8(+) T cells sabotage their own memory potential through IFN-?-dependent modification of the IL-12/IL-15 receptor a axis on dendritic cells. J Immunol. 2012 Apr 15; 188(8):3639-47. PMID: 22430740.
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    37. Rubinstein MP, Cloud CA, Garrett TE, Moore CJ, Schwartz KM, Johnson CB, Craig DH, Salem ML, Paulos CM, Cole DJ. Ex vivo interleukin-12-priming during CD8(+) T cell activation dramatically improves adoptive T cell transfer antitumor efficacy in a lymphodepleted host. J Am Coll Surg. 2012 Apr; 214(4):700-7; discussion 707-8. PMID: 22360982.
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    38. Keen SD, Cole DJ. Bias-free identification of a linear model-predictive steering controller from measured driver steering behavior. IEEE Trans Syst Man Cybern B Cybern. 2012 Apr; 42(2):434-43. PMID: 22334024.
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    39. Little EC, Wang C, Watson PM, Watson DK, Cole DJ, Camp ER. Novel immunocompetent murine models representing advanced local and metastatic pancreatic cancer. J Surg Res. 2012 Aug; 176(2):359-66. PMID: 22221605.
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    40. Díaz-Montero CM, Naga O, Zidan AA, Salem ML, Pallin M, Parmigiani A, Walker G, Wieder E, Komanduri K, Cole DJ, Montero AJ, Lichtenheld MG. Synergy of brief activation of CD8 T-cells in the presence of IL-12 and adoptive transfer into lymphopenic hosts promotes tumor clearance and anti-tumor memory. Am J Cancer Res. 2011 Aug 30; 1(7):882-96. PMID: 21915391.
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    41. Esnaola NF, Cole DJ. Perioperative normothermia during major surgery: is it important? Adv Surg. 2011; 45:249-63. PMID: 21954692.
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    42. Lehtinen SJ, Onicescu G, Kuhn KM, Cole DJ, Esnaola NF. Normothermia to prevent surgical site infections after gastrointestinal surgery: holy grail or false idol? Ann Surg. 2010 Oct; 252(4):696-704. PMID: 20881777.
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    43. Salem ML, Demcheva M, Gillanders WE, Cole DJ, Vournakis JN. Poly-N-acetyl glucosamine gel matrix as a non-viral delivery vector for DNA-based vaccination. Anticancer Res. 2010 Oct; 30(10):3889-94. PMID: 21036699.
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    44. Fisher CS, Cole DJ, Mitas M, Garrett-Meyer E, Metcalf JS, Gillanders WE, Mikhitarian K, Urist MM, Mann GB, Doherty G, Herrmann VM, Hill AD, Eremin O, El-Sheemy M, Orr RK, Valle AA, Henderson MA, Dewitty RL, Sugg SL, Frykberg E, Yeh K, Bell RM, Baker MK. Molecular detection of micrometastatic breast cancer in histopathology-negative axillary lymph nodes fails to predict breast cancer recurrence: a final analysis of a prospective multi-institutional cohort study. Ann Surg Oncol. 2010 Oct; 17 Suppl 3:312-20. PMID: 20853052.
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    45. Crawford FA, Cole DJ. The Department of Surgery at the Medical University of South Carolina (1824-2010). Am Surg. 2010 Sep; 76(9):925-32. PMID: 20836336.
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    46. Salem ML, Al-Khami AA, El-Naggar SA, Díaz-Montero CM, Chen Y, Cole DJ. Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a Flt3 ligand-dependent expansion of dendritic cells. J Immunol. 2010 Feb 15; 184(4):1737-47. PMID: 20083664.
      View in: PubMed
    47. Salem ML, El-Naggar SA, Cole DJ. Cyclophosphamide induces bone marrow to yield higher numbers of precursor dendritic cells in vitro capable of functional antigen presentation to T cells in vivo. Cell Immunol. 2010; 261(2):134-43. PMID: 20036354.
      View in: PubMed
    48. Salem ML, Cole DJ. Dendritic cell recovery post-lymphodepletion: a potential mechanism for anti-cancer adoptive T cell therapy and vaccination. Cancer Immunol Immunother. 2010 Mar; 59(3):341-53. PMID: 19921513.
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    49. Harper JL, Watkins JM, Zauls AJ, Wahlquist AE, Garrett-Mayer E, Baker MK, Cole DJ, Dragun AE, Jenrette JM. Six-year experience: long-term disease control outcomes for partial breast irradiation using MammoSite balloon brachytherapy. Am J Surg. 2010 Feb; 199(2):204-9. PMID: 19837390.
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    50. Hughes SJ, Xi L, Gooding WE, Cole DJ, Mitas M, Metcalf J, Bhargava R, Dabbs D, Ching J, Kozma L, McMillan W, Godfrey TE. A quantitative reverse transcription-PCR assay for rapid, automated analysis of breast cancer sentinel lymph nodes. J Mol Diagn. 2009 Nov; 11(6):576-82. PMID: 19797614.
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    51. Salem ML, Díaz-Montero CM, Al-Khami AA, El-Naggar SA, Naga O, Montero AJ, Khafagy A, Cole DJ. Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C). J Immunol. 2009 Feb 15; 182(4):2030-40. PMID: 19201856.
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    52. Mason PC, Hosking BC, Nottingham RM, Cole DJ, Seewald W, McKay CH, Griffiths TM, Kaye-Smith BG, Chamberlain B. A large-scale clinical field study to evaluate the efficacy and safety of an oral formulation of the amino-acetonitrile derivative ( AAD ), monepantel , in sheep in New Zealand. N Z Vet J. 2009 Feb; 57(1):3-9. PMID: 19252536.
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    53. Salem ML, Diaz-Montero CM, El-Naggar SA, Chen Y, Moussa O, Cole DJ. The TLR3 agonist poly(I:C) targets CD8+ T cells and augments their antigen-specific responses upon their adoptive transfer into naïve recipient mice. Vaccine. 2009 Jan 22; 27(4):549-57. PMID: 19027047.
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    54. Watkins JM, Harper JL, Dragun AE, Ashenafi MS, Sinha D, Li J, Cole DJ, Jenrette JM. Incidence and prognostic factors for seroma development after MammoSite breast brachytherapy. Brachytherapy. 2008 Oct-Dec; 7(4):305-9. PMID: 18778970.
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    55. Blum C, Graham A, Yousefzadeh M, Shrout J, Benjamin K, Krishna M, Hoda R, Hoda R, Cole DJ, Garrett-Mayer E, Reed C, Wallace M, Mitas M. The expression ratio of Map7/B2M is prognostic for survival in patients with stage II colon cancer. Int J Oncol. 2008 Sep; 33(3):579-84. PMID: 18695889.
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    56. Rubinstein MP, Salem ML, Kadima AN, Nguyen CL, Gillanders WE, Nishimura MI, Cole DJ. Loss of T cell-mediated antitumor immunity after construct-specific downregulation of retrovirally encoded T-cell receptor expression in vivo. Cancer Gene Ther. 2009 Feb; 16(2):171-83. PMID: 18690205.
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    57. Diaz-Montero CM, Salem ML, Nishimura MI, Garrett-Mayer E, Cole DJ, Montero AJ. Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol Immunother. 2009 Jan; 58(1):49-59. PMID: 18446337.
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    58. Mikhitarian K, Martin RH, Ruppel MB, Gillanders WE, Hoda R, Schutte del H, Callahan K, Mitas M, Cole DJ. Detection of mammaglobin mRNA in peripheral blood is associated with high grade breast cancer: interim results of a prospective cohort study. BMC Cancer. 2008 Feb 20; 8:55. PMID: 18289390.
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    59. Watson PM, Miller SW, Fraig M, Cole DJ, Watson DK, Boylan AM. CaSm (LSm-1) overexpression in lung cancer and mesothelioma is required for transformed phenotypes. Am J Respir Cell Mol Biol. 2008 Jun; 38(6):671-8. PMID: 18218995.
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    60. Díaz-Montero CM, El Naggar S, Al Khami A, El Naggar R, Montero AJ, Cole DJ, Salem ML. Priming of naive CD8+ T cells in the presence of IL-12 selectively enhances the survival of CD8+CD62Lhi cells and results in superior anti-tumor activity in a tolerogenic murine model. Cancer Immunol Immunother. 2008 Apr; 57(4):563-72. PMID: 17726606.
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    61. Chen Y, Zheng B, Robbins DH, Lewin DN, Mikhitarian K, Graham A, Rumpp L, Glenn T, Gillanders WE, Cole DJ, Lu X, Hoffman BJ, Mitas M. Accurate discrimination of pancreatic ductal adenocarcinoma and chronic pancreatitis using multimarker expression data and samples obtained by minimally invasive fine needle aspiration. Int J Cancer. 2007 Apr 01; 120(7):1511-7. PMID: 17192896.
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    62. Dragun AE, Harper JL, Jenrette JM, Sinha D, Cole DJ. Predictors of cosmetic outcome following MammoSite breast brachytherapy: a single-institution experience of 100 patients with two years of follow-up. Int J Radiat Oncol Biol Phys. 2007 Jun 01; 68(2):354-8. PMID: 17383829.
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    63. Salem ML, Kadima AN, El-Naggar SA, Rubinstein MP, Chen Y, Gillanders WE, Cole DJ. Defining the ability of cyclophosphamide preconditioning to enhance the antigen-specific CD8+ T-cell response to peptide vaccination: creation of a beneficial host microenvironment involving type I IFNs and myeloid cells. J Immunother. 2007 Jan; 30(1):40-53. PMID: 17198082.
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    64. Salem ML, Gillanders WE, Kadima AN, El-Naggar S, Rubinstein MP, Demcheva M, Vournakis JN, Cole DJ. Review: novel nonviral delivery approaches for interleukin-12 protein and gene systems: curbing toxicity and enhancing adjuvant activity. J Interferon Cytokine Res. 2006 Sep; 26(9):593-608. PMID: 16978064.
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    65. Salem ML, El-Naggar SA, Kadima A, Gillanders WE, Cole DJ. The adjuvant effects of the toll-like receptor 3 ligand polyinosinic-cytidylic acid poly (I:C) on antigen-specific CD8+ T cell responses are partially dependent on NK cells with the induction of a beneficial cytokine milieu. Vaccine. 2006 Jun 12; 24(24):5119-32. PMID: 16704888.
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    66. Hughes SJ, Xi L, Raja S, Gooding W, Cole DJ, Gillanders WE, Mikhitarian K, McCarty K, Silver S, Ching J, McMillan W, Luketich JD, Godfrey TE. A rapid, fully automated, molecular-based assay accurately analyzes sentinel lymph nodes for the presence of metastatic breast cancer. Ann Surg. 2006 Mar; 243(3):389-98. PMID: 16495705.
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    67. Lou E, Marshall J, Aklilu M, Cole D, Chang D, Morse M. A phase II study of active immunotherapy with PANVAC or autologous, cultured dendritic cells infected with PANVAC after complete resection of hepatic metastases of colorectal carcinoma. Clin Colorectal Cancer. 2006 Jan; 5(5):368-71. PMID: 16512998.
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    68. Yan Y, Rubinchik S, Wood AL, Gillanders WE, Dong JY, Watson DK, Cole DJ. Bystander effect contributes to the antitumor efficacy of CaSm antisense gene therapy in a preclinical model of advanced pancreatic cancer. Mol Ther. 2006 Feb; 13(2):357-65. PMID: 16226492.
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    69. Mikhitarian K, Martin RH, Mitas M, Mauldin PD, Palesch Y, Metcalf JS, Cole DJ, Gillanders WE. Molecular analysis improves sensitivity of breast sentinel lymph node biopsy: results of a multi-institutional prospective cohort study. Surgery. 2005 Sep; 138(3):474-81. PMID: 16213901.
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    70. Fraser MM, Watson PM, Fraig MM, Kelley JR, Nelson PS, Boylan AM, Cole DJ, Watson DK. CaSm-mediated cellular transformation is associated with altered gene expression and messenger RNA stability. Cancer Res. 2005 Jul 15; 65(14):6228-36. PMID: 16024624.
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    71. Mikhitarian K, Gillanders WE, Almeida JS, Hebert Martin R, Varela JC, Metcalf JS, Cole DJ, Mitas M. An innovative microarray strategy identities informative molecular markers for the detection of micrometastatic breast cancer. Clin Cancer Res. 2005 May 15; 11(10):3697-704. PMID: 15897566.
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    72. Salem ML, Kadima AN, Cole DJ, Gillanders WE. Defining the antigen-specific T-cell response to vaccination and poly(I:C)/TLR3 signaling: evidence of enhanced primary and memory CD8 T-cell responses and antitumor immunity. J Immunother. 2005 May-Jun; 28(3):220-8. PMID: 15838378.
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    73. Mitas M, Almeida JS, Mikhitarian K, Gillanders WE, Lewin DN, Spyropoulos DD, Hoover L, Graham A, Glenn T, King P, Cole DJ, Hawes R, Reed CE, Hoffman BJ. Accurate discrimination of Barrett's esophagus and esophageal adenocarcinoma using a quantitative three-tiered algorithm and multimarker real-time reverse transcription-PCR. Clin Cancer Res. 2005 Mar 15; 11(6):2205-14. PMID: 15788668.
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    74. Yan Y, Rubinchik S, Watson PM, Kelley JR, Fraser MM, Wood AL, Dong JY, Gillanders WE, Boylan AM, Watson DK, Cole DJ. Establishing a murine pancreatic cancer CaSm model: up-regulation of CaSm is required for the transformed phenotype of murine pancreatic adenocarcinoma. Mol Ther. 2005 Mar; 11(3):363-72. PMID: 15727932.
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    75. Wallace MB, Block MI, Gillanders W, Ravenel J, Hoffman BJ, Reed CE, Fraig M, Cole D, Mitas M. Accurate molecular detection of non-small cell lung cancer metastases in mediastinal lymph nodes sampled by endoscopic ultrasound-guided needle aspiration. Chest. 2005 Feb; 127(2):430-7. PMID: 15705978.
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    76. Osta WA, Chen Y, Mikhitarian K, Mitas M, Salem M, Hannun YA, Cole DJ, Gillanders WE. EpCAM is overexpressed in breast cancer and is a potential target for breast cancer gene therapy. Cancer Res. 2004 Aug 15; 64(16):5818-24. PMID: 15313925.
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    77. Schwaitzberg SD, Chan MW, Cole DJ, Read M, Nichols T, Bellinger D, Connolly RJ. Comparison of poly-N-acetyl glucosamine with commercially available topical hemostats for achieving hemostasis in coagulopathic models of splenic hemorrhage. J Trauma. 2004 Jul; 57(1 Suppl):S29-32. PMID: 15280748.
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    78. Gillanders WE, Mikhitarian K, Hebert R, Mauldin PD, Palesch Y, Walters C, Urist MM, Mann GB, Doherty G, Herrmann VM, Hill AD, Eremin O, El-Sheemy M, Orr RK, Valle AA, Henderson MA, Dewitty RL, Sugg SL, Frykberg E, Yeh K, Bell RM, Metcalf JS, Elliott BM, Brothers T, Robison J, Mitas M, Cole DJ. Molecular detection of micrometastatic breast cancer in histopathology-negative axillary lymph nodes correlates with traditional predictors of prognosis: an interim analysis of a prospective multi-institutional cohort study. Ann Surg. 2004 Jun; 239(6):828-37; discussion 837-40. PMID: 15166962.
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    79. Salem ML, Kadima AN, Zhou Y, Nguyen CL, Rubinstein MP, Demcheva M, Vournakis JN, Cole DJ, Gillanders WE. Paracrine release of IL-12 stimulates IFN-gamma production and dramatically enhances the antigen-specific T cell response after vaccination with a novel peptide-based cancer vaccine. J Immunol. 2004 May 01; 172(9):5159-67. PMID: 15100252.
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    80. Mikhitarian K, Reott S, Hoover L, Allen A, Cole DJ, Gillanders WE, Mitas M. Enhanced detection of RNA from paraffin-embedded tissue using a panel of truncated gene-specific primers for reverse transcription. Biotechniques. 2004 Mar; 36(3):474-8. PMID: 15038162.
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    81. Mitas M, Hoover L, Silvestri G, Reed C, Green M, Turrisi AT, Sherman C, Mikhitarian K, Cole DJ, Block MI, Gillanders WE. Lunx is a superior molecular marker for detection of non-small cell lung cancer in peripheral blood [corrected]. J Mol Diagn. 2003 Nov; 5(4):237-42. PMID: 14573783.
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    82. Baker MK, Mikhitarian K, Osta W, Callahan K, Hoda R, Brescia F, Kneuper-Hall R, Mitas M, Cole DJ, Gillanders WE. Molecular detection of breast cancer cells in the peripheral blood of advanced-stage breast cancer patients using multimarker real-time reverse transcription-polymerase chain reaction and a novel porous barrier density gradient centrifugation technology. Clin Cancer Res. 2003 Oct 15; 9(13):4865-71. PMID: 14581359.
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    83. Price LJ, Herbert D, Moss SR, Cole DJ, Harwood JL. Graminicide insensitivity correlates with herbicide-binding co-operativity on acetyl-CoA carboxylase isoforms. Biochem J. 2003 Oct 15; 375(Pt 2):415-23. PMID: 12859251.
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    84. Baker M, Gillanders WE, Mikhitarian K, Mitas M, Cole DJ. The molecular detection of micrometastatic breast cancer. Am J Surg. 2003 Oct; 186(4):351-8. PMID: 14553849.
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    85. Brazier M, Cole DJ, Edwards R. Partial purification and characterisation of a 2,4,5-trichlorophenol detoxifying O-glucosyltransferase from wheat. Phytochemistry. 2003 Sep; 64(2):419-24. PMID: 12943758.
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    86. Price LJ, Herbert D, Cole DJ, Harwood JL. Use of plant cell cultures to study graminicide effects on lipid metabolism. Phytochemistry. 2003 Jul; 63(5):533-41. PMID: 12809713.
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    87. Lao SH, Loutre C, Brazier M, Coleman JO, Cole DJ, Edwards R, Theodoulou FL. 3,4-Dichloroaniline is detoxified and exported via different pathways in Arabidopsis and soybean. Phytochemistry. 2003 Jul; 63(6):653-61. PMID: 12842137.
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    88. Nguyen CL, Salem ML, Rubinstein MP, Demcheva M, Vournakis JN, Cole DJ, Gillanders WE. Mechanisms of enhanced antigen-specific T cell response following vaccination with a novel peptide-based cancer vaccine and systemic interleukin-2 (IL-2). Vaccine. 2003 Jun 02; 21(19-20):2318-28. PMID: 12744862.
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    89. Cummins I, O'Hagan D, Jablonkai I, Cole DJ, Hehn A, Werck-Reichhart D, Edwards R. Cloning, characterization and regulation of a family of phi class glutathione transferases from wheat. Plant Mol Biol. 2003 Jun; 52(3):591-603. PMID: 12956529.
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    90. Kelley JR, Fraser MM, Hubbard JM, Watson DK, Cole DJ. CaSm antisense gene therapy: a novel approach for the treatment of pancreatic cancer. Anticancer Res. 2003 May-Jun; 23(3A):2007-13. PMID: 12894573.
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    91. Loutre C, Dixon DP, Brazier M, Slater M, Cole DJ, Edwards R. Isolation of a glucosyltransferase from Arabidopsis thaliana active in the metabolism of the persistent pollutant 3,4-dichloroaniline. Plant J. 2003 May; 34(4):485-93. PMID: 12753587.
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    92. Roszkowski JJ, Yu DC, Rubinstein MP, McKee MD, Cole DJ, Nishimura MI. CD8-independent tumor cell recognition is a property of the T cell receptor and not the T cell. J Immunol. 2003 Mar 01; 170(5):2582-9. PMID: 12594285.
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    93. Mitas M, Cole DJ, Hoover L, Fraig MM, Mikhitarian K, Block MI, Hoffman BJ, Hawes RH, Gillanders WE, Wallace MB. Real-time reverse transcription-PCR detects KS1/4 mRNA in mediastinal lymph nodes from patients with non-small cell lung cancer. Clin Chem. 2003 Feb; 49(2):312-5. PMID: 12560358.
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    94. Theodoulou FL, Clark IM, He XL, Pallett KE, Cole DJ, Hallahan DL. Co-induction of glutathione-S-transferases and multidrug resistance associated protein by xenobiotics in wheat. Pest Manag Sci. 2003 Feb; 59(2):202-14. PMID: 12587874.
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    95. Rubinstein MP, Kadima AN, Salem ML, Nguyen CL, Gillanders WE, Nishimura MI, Cole DJ. Transfer of TCR genes into mature T cells is accompanied by the maintenance of parental T cell avidity. J Immunol. 2003 Feb 01; 170(3):1209-17. PMID: 12538678.
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    96. Rubinstein MP, Kadima AN, Salem ML, Nguyen CL, Gillanders WE, Cole DJ. Systemic administration of IL-15 augments the antigen-specific primary CD8+ T cell response following vaccination with peptide-pulsed dendritic cells. J Immunol. 2002 Nov 01; 169(9):4928-35. PMID: 12391205.
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    97. Cole DJ, Bertagnolli MM, Nussbaum M. Society of University Surgeons statement on surgical resident work hours and education. Surgery. 2002 Aug; 132(2):115-8. PMID: 12219000.
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    98. Thom R, Cummins I, Dixon DP, Edwards R, Cole DJ, Lapthorn AJ. Structure of a tau class glutathione S-transferase from wheat active in herbicide detoxification. Biochemistry. 2002 Jun 04; 41(22):7008-20. PMID: 12033934.
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    99. Mitas M, Mikhitarian K, Hoover L, Lockett MA, Kelley L, Hill A, Gillanders WE, Cole DJ. Prostate-Specific Ets (PSE) factor: a novel marker for detection of metastatic breast cancer in axillary lymph nodes. Br J Cancer. 2002 Mar 18; 86(6):899-904. PMID: 11953821.
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    100. Lucas DG, Lockett MA, Cole DJ. Spontaneous infarction of a parathyroid adenoma: two case reports and review of the literature. Am Surg. 2002 Feb; 68(2):173-6. PMID: 11842966.
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    101. Brazier M, Cole DJ, Edwards R. O-Glucosyltransferase activities toward phenolic natural products and xenobiotics in wheat and herbicide-resistant and herbicide-susceptible black-grass (Alopecurus myosuroides). Phytochemistry. 2002 Jan; 59(2):149-56. PMID: 11809449.
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    102. Nguyen CL, Bui JT, Demcheva M, Vournakis JN, Cole DJ, Gillanders WE. Sustained release of granulocyte-macrophage colony-stimulating factor from a modular peptide-based cancer vaccine alters vaccine microenvironment and enhances the antigen-specific T-cell response. J Immunother. 2001 Sep-Oct; 24(5):420-9. PMID: 11696697.
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    103. Nguyen CL, Bui JT, Demcheva M, Vournakis JN, Cole DJ, Gillanders WE. Sustained Release of Granulocyte-Macrophage Colony-Stimulating Factor From a Modular Peptide-Based Cancer Vaccine Alters Vaccine Microenvironment and Enhances the Antigen-Specific T-Cell Response. J Immunother (1991). 2001 Sep-Oct; 24(5):420-429. PMID: 11685084.
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    104. Kelley JR, Fraser MM, Schweinfest CW, Vournakis JN, Watson DK, Cole DJ. CaSm/gemcitabine chemo-gene therapy leads to prolonged survival in a murine model of pancreatic cancer. Surgery. 2001 Aug; 130(2):280-8. PMID: 11490361.
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    105. Mitas M, Mikhitarian K, Walters C, Baron PL, Elliott BM, Brothers TE, Robison JG, Metcalf JS, Palesch YY, Zhang Z, Gillanders WE, Cole DJ. Quantitative real-time RT-PCR detection of breast cancer micrometastasis using a multigene marker panel. Int J Cancer. 2001 Jul 15; 93(2):162-71. PMID: 11410861.
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    106. Thom R, Dixon DP, Edwards R, Cole DJ, Lapthorn AJ. The structure of a zeta class glutathione S-transferase from Arabidopsis thaliana: characterisation of a GST with novel active-site architecture and a putative role in tyrosine catabolism. J Mol Biol. 2001 May 18; 308(5):949-62. PMID: 11352584.
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    107. Nguyen CL, McClay EF, Cole DJ, O'Brien PH, Gillanders WE, Metcalf JS, Maize JC, Baron PL. Melanoma thickness and histology predict sentinel lymph node status. Am J Surg. 2001 Jan; 181(1):8-11. PMID: 11248167.
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    108. Benedict S, Cole DJ, Baron L, Baron P. Factors influencing choice between mastectomy and lumpectomy for women in the Carolinas. J Surg Oncol. 2001 Jan; 76(1):6-12. PMID: 11223818.
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    109. Dixon DP, Cole DJ, Edwards R. Characterisation of a zeta class glutathione transferase from Arabidopsis thaliana with a putative role in tyrosine catabolism. Arch Biochem Biophys. 2000 Dec 15; 384(2):407-12. PMID: 11368331.
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    110. Kelley JR, Brown JM, Frasier MM, Baron PL, Schweinfest CW, Vournakis JN, Watson DK, Cole DJ. The cancer-associated Sm-like oncogene: a novel target for the gene therapy of pancreatic cancer. Surgery. 2000 Aug; 128(2):353-60. PMID: 10923016.
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    111. McClay EF, McClay ME, Monroe L, Baron PL, Cole DJ, O'Brien PH, Metcalf JS, Maize JC. The effect of tamoxifen and cisplatin on the disease-free and overall survival of patients with high risk malignant melanoma. Br J Cancer. 2000 Jul; 83(1):16-21. PMID: 10883662.
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    112. Ritvo P, Robinson G, Irvine J, Brown L, Matthew A, Murphy KJ, Stewart DS, Styra R, Wang C, Mullen M, Cole D, Rosen B. Psychological adjustment to familial genetic risk assessment: differences in two longitudinal samples. Patient Educ Couns. 2000 May; 40(2):163-72. PMID: 10771370.
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    113. Cole DJ, Baron PL, O'Brien P, Reed CE, Schlom J, Tsang KY. Phase I study of recombinant carcinoembryonic antigen (CEA) vaccinia virus vaccine with post vaccination carcinoembryonic antigen peptide (CAP-1) boost. Clin Lung Cancer. 2000 Feb; 1(3):227-9. PMID: 14733650.
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    114. Zhu MZ, Marshall J, Cole D, Schlom J, Tsang KY. Specific cytolytic T-cell responses to human CEA from patients immunized with recombinant avipox-CEA vaccine. Clin Cancer Res. 2000 Jan; 6(1):24-33. PMID: 10656428.
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    115. Clark JW, Snell L, Shiu RP, Orr FW, Maitre N, Vary CP, Cole DJ, Watson PH. The potential role for prolactin-inducible protein (PIP) as a marker of human breast cancer micrometastasis. Br J Cancer. 1999 Nov; 81(6):1002-8. PMID: 10576657.
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    116. Cole DJ, Connolly RJ, Chan MW, Schwaitzberg SD, Byrne TK, Adams DB, Baron PL, O'Brien PH, Metcalf JS, Demcheva M, Vournakis J. A pilot study evaluating the efficacy of a fully acetylated poly-N-acetyl glucosamine membrane formulation as a topical hemostatic agent. Surgery. 1999 Sep; 126(3):510-7. PMID: 10486603.
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    117. Ritvo P, Robinson G, Irvine J, Brown L, Murphy KJ, Stewart DS, Styra R, Wang C, Mullen M, Cole D, Rosen B. A longitudinal study of psychological adjustment to familial genetic risk assessment for ovarian cancer. Gynecol Oncol. 1999 Sep; 74(3):331-7. PMID: 10479489.
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    118. Rios G, Conrad A, Cole D, Adams D, Leveen M, O'Brien P, Baron P. Trends in indications and outcomes in the Whipple procedure over a 40-year period. Am Surg. 1999 Sep; 65(9):889-93. PMID: 10484097.
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    119. Dixon DP, Cole DJ, Edwards R. Dimerisation of maize glutathione transferases in recombinant bacteria. Plant Mol Biol. 1999 Aug; 40(6):997-1008. PMID: 10527424.
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    120. Cummins I, Cole DJ, Edwards R. A role for glutathione transferases functioning as glutathione peroxidases in resistance to multiple herbicides in black-grass. Plant J. 1999 May; 18(3):285-92. PMID: 10377994.
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    121. Maitre N, Brown JM, Demcheva M, Kelley JR, Lockett MA, Vournakis J, Cole DJ. Primary T-cell and activated macrophage response associated with tumor protection using peptide/poly-N-acetyl glucosamine vaccination. Clin Cancer Res. 1999 May; 5(5):1173-82. PMID: 10353754.
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    122. Cole DJ, Reynolds LW, Nary JC, Drummond JC, Patel PM, Jacobsen WK. Subarachnoid hemorrhage in rats: effect of singular or sustained hemodilution with alpha-alpha diaspirin crosslinked hemoglobin on cerebral hypoperfusion. Crit Care Med. 1999 May; 27(5):972-7. PMID: 10362422.
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    123. Grunfeld E, Gray A, Mant D, Yudkin P, Adewuyi-Dalton R, Coyle D, Cole D, Stewart J, Fitzpatrick R, Vessey M. Follow-up of breast cancer in primary care vs specialist care: results of an economic evaluation. Br J Cancer. 1999 Mar; 79(7-8):1227-33. PMID: 10098764.
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    124. Lockett MA, Baron PL, O'Brien PH, Elliott BM, Robison JG, Maitre N, Metcalf JS, Cole DJ. Detection of occult breast cancer micrometastases in axillary lymph nodes using a multimarker reverse transcriptase-polymerase chain reaction panel. J Am Coll Surg. 1998 Jul; 187(1):9-16. PMID: 9660019.
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    125. Lockett MA, Metcalf JS, Baron PL, O'Brien PH, Elliott BM, Robison JG, Cole DJ. Efficacy of reverse transcriptase-polymerase chain reaction screening for micrometastic disease in axillary lymph nodes of breast cancer patients. Am Surg. 1998 Jun; 64(6):539-43; discussion 543-4. PMID: 9619175.
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    126. Dixon DP, Cummins L, Cole DJ, Edwards R. Glutathione-mediated detoxification systems in plants. Curr Opin Plant Biol. 1998 Jun; 1(3):258-66. PMID: 10066594.
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    127. Houck WV, Kaplan AJ, Reed CE, Cole DJ. Intrathoracic aberrant thyroid: identification critical for appropriate operative approach. Am Surg. 1998 Apr; 64(4):360-2. PMID: 9544150.
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    128. Dixon DP, Cole DJ, Edwards R. Purification, regulation and cloning of a glutathione transferase (GST) from maize resembling the auxin-inducible type-III GSTs. Plant Mol Biol. 1998 Jan; 36(1):75-87. PMID: 9484464.
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    129. Pitre B, Baron PL, Baron LF, O'Brien PH, Cole DJ. Stereotactic core biopsy of the breast: results of one-year follow-up of 101 patients. Am Surg. 1997 Dec; 63(12):1124-7. PMID: 9393264.
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    130. Cole DJ, Wilson MC, Rivoltini L, Custer M, Nishimura MI. T-cell receptor repertoire in matched MART-1 peptide-stimulated peripheral blood lymphocytes and tumor-infiltrating lymphocytes. Cancer Res. 1997 Dec 01; 57(23):5320-7. PMID: 9393756.
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    131. Baron PL, Aabakken LE, Cole DJ, LeVeen MB, Baron LF, Daniel DM, Cunningham JT, Hawes RH, Adams DB, Hoffman BJ. Differentiation of benign from malignant pancreatic masses by endoscopic ultrasound. Ann Surg Oncol. 1997 Dec; 4(8):639-43. PMID: 9416411.
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    132. Tsang KY, Zhu M, Nieroda CA, Correale P, Zaremba S, Hamilton JM, Cole D, Lam C, Schlom J. Phenotypic stability of a cytotoxic T-cell line directed against an immunodominant epitope of human carcinoembryonic antigen. Clin Cancer Res. 1997 Dec; 3(12 Pt 1):2439-49. PMID: 9815645.
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    133. Feldman DR, Kulling DP, Kay CL, Cole DJ, Cunningham JT, Hawes RH, Tarnasky PR, Cotton PB, Baron PL. Magnetic resonance cholangiopancreatography: a novel approach to the evaluation of suspected pancreaticobiliary neoplasms. Ann Surg Oncol. 1997 Dec; 4(8):634-8. PMID: 9416410.
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    134. Shilyansky J, Yang JC, Custer MC, Spiess P, Mixon A, Cole DJ, Mulé JJ, Rosenberg SA, Nishimura MI. Identification of a T-cell receptor from a therapeutic murine T-cell clone. J Immunother. 1997 Jul; 20(4):247-55. PMID: 9220314.
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    135. Cole DJ, Gattoni-Celli S, McClay EF, Metcalf JS, Brown JM, Nabavi N, Newton DA, Woolhiser CB, Wilson MC, Vournakis JN. Characterization of a sustained-release delivery system for combined cytokine/peptide vaccination using a poly-N-acetyl glucosamine-based polymer matrix. Clin Cancer Res. 1997 Jun; 3(6):867-73. PMID: 9815761.
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    136. Gattoni-Celli S, Cole DJ. Melanoma-associated tumor antigens and their clinical relevance to immunotherapy. Semin Oncol. 1996 Dec; 23(6):754-8. PMID: 8970598.
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    137. Cole DJ, Baron PL. Surgical management of patients with intermediate thickness melanoma: current role of elective lymph node dissection. Semin Oncol. 1996 Dec; 23(6):719-24. PMID: 8970593.
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    138. Herbert D, Price LJ, Alban C, Dehaye L, Job D, Cole DJ, Pallett KE, Harwood JL. Kinetic studies on two isoforms of acetyl-CoA carboxylase from maize leaves. Biochem J. 1996 Sep 15; 318 ( Pt 3):997-1006. PMID: 8836149.
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    139. Cole DJ, Wilson MC, Baron PL, O'Brien P, Reed C, Tsang KY, Schlom J. Phase I study of recombinant CEA vaccinia virus vaccine with post vaccination CEA peptide challenge. Hum Gene Ther. 1996 Jul 10; 7(11):1381-94. PMID: 8818725.
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    140. Roilides E, Lyman CA, Mertins SD, Cole DJ, Venzon D, Pizzo PA, Chanock SJ, Walsh TJ. Ex vivo effects of macrophage colony-stimulating factor on human monocyte activity against fungal and bacterial pathogens. Cytokine. 1996 Jan; 8(1):42-8. PMID: 8742065.
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    141. Cole DJ, Weil DP, Shilyansky J, Custer M, Kawakami Y, Rosenberg SA, Nishimura MI. Characterization of the functional specificity of a cloned T-cell receptor heterodimer recognizing the MART-1 melanoma antigen. Cancer Res. 1995 Feb 15; 55(4):748-52. PMID: 7531614.
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    142. Hug EB, Spiro IJ, Cole DJ, Suit HD. Combined surgery and radiotherapy for conservative management of soft tissue sarcomas. Recent Results Cancer Res. 1995; 138:47-55. PMID: 7899698.
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    143. Cole DJ, Weil DP, Shamamian P, Rivoltini L, Kawakami Y, Topalian S, Jennings C, Eliyahu S, Rosenberg SA, Nishimura MI. Identification of MART-1-specific T-cell receptors: T cells utilizing distinct T-cell receptor variable and joining regions recognize the same tumor epitope. Cancer Res. 1994 Oct 15; 54(20):5265-8. PMID: 7522957.
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    144. Herbert D, Alban C, Cole DJ, Pallett KE, Harwood JL. Characteristics of two forms of acetyl-CoA carboxylase from maize leaves. Biochem Soc Trans. 1994 Aug; 22(3):261S. PMID: 7821523.
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    145. Cole DJ, Ettinghausen SE, Pass HI, Danforth DN, Linehan MW, Myers CW, Cooper MR, Sindelar WF. Postoperative complications in patients receiving suramin therapy. Surgery. 1994 Jul; 116(1):90-5. PMID: 8023275.
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    146. Cole DJ, Taubenberger JK, Pockaj BA, Yannelli JR, Carter C, Carrasquillo J, Leitman S, Steinberg SM, Rosenberg SA, Yang YC. Histopathological analysis of metastatic melanoma deposits in patients receiving adoptive immunotherapy with tumor-infiltrating lymphocytes. Cancer Immunol Immunother. 1994 May; 38(5):299-303. PMID: 8162611.
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    147. Cole DJ, Sanda MG, Yang JC, Schwartzentruber DJ, Weber J, Ettinghausen SE, Pockaj BA, Kim HI, Levin RD, Pogrebniak HW, et al. Phase I trial of recombinant human macrophage colony-stimulating factor administered by continuous intravenous infusion in patients with metastatic cancer. J Natl Cancer Inst. 1994 Jan 05; 86(1):39-45. PMID: 8271281.
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    148. Sano T, Patel PM, Drummond JC, Cole DJ. Combined therapy with dizocilpine and levemopamil does not reduce ischemic neuronal injury in rats. J Neurosurg Anesthesiol. 1993 Jul; 5(3):194-201. PMID: 8400759.
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    149. Herbert D, Cole DJ, Pallett KE, Harwood JL. Differential sensitivity of lipid metabolism in monocotyledons to grass-specific herbicides. Biochem Soc Trans. 1993 May; 21(2):183S. PMID: 8359436.
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    150. Weber J, Yang JC, Topalian SL, Parkinson DR, Schwartzentruber DS, Ettinghausen SE, Gunn H, Mixon A, Kim H, Cole D, et al. Phase I trial of subcutaneous interleukin-6 in patients with advanced malignancies. J Clin Oncol. 1993 Mar; 11(3):499-506. PMID: 7680375.
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    151. Cole DJ, Mackay GJ, Walker BF, Wooden WA, Murray DR, Coleman JJ. Melanoma of the external ear. J Surg Oncol. 1992 Jun; 50(2):110-4. PMID: 1593881.
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    152. Cole DJ, Brown DC, Crossley E, Alcock CJ, Gatter KC. Carcinoma of the cervix uteri: an assessment of the relationship of tumour proliferation to prognosis. Br J Cancer. 1992 May; 65(5):783-5. PMID: 1586610.
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    153. Cole DJ, Ferguson CM. Complications of hepatic resection for colorectal carcinoma metastasis. Am Surg. 1992 Feb; 58(2):88-91. PMID: 1550311.
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    154. Sano T, Drummond JC, Patel PM, Grafe MR, Watson JC, Cole DJ. A comparison of the cerebral protective effects of isoflurane and mild hypothermia in a model of incomplete forebrain ischemia in the rat. Anesthesiology. 1992 Feb; 76(2):221-8. PMID: 1736699.
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    155. Patel PM, Drummond JC, Cole DJ. Induced hypertension during restoration of flow after temporary middle cerebral artery occlusion in the rat: effect on neuronal injury and edema. Surg Neurol. 1991 Sep; 36(3):195-201. PMID: 1876969.
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    156. Ashton IP, Pallett KE, Cole DJ, Harwood JL. The effect of diflufenican on lipid metabolism in plants. Biochem Soc Trans. 1991 Aug; 19(3):320S. PMID: 1838339.
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    157. Patel PM, Drummond JC, Cole DJ, Giamela R, Steinauer J. Delayed institution of hypertension during focal cerebral ischemia: effect on brain edema. Acta Neuropathol. 1991; 81(3):339-44. PMID: 1711760.
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    158. Colamonici OR, Rosolen A, Cole D, Kirsch I, Felix C, Poplack DG, Neckers LM. Stimulation of the beta-subunit of the IL-2 receptor induces MHC-unrestricted cytotoxicity in T acute lymphoblastic leukemia cells and normal thymocytes. J Immunol. 1988 Aug 15; 141(4):1202-5. PMID: 3135323.
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    159. Glenn EH, Cole D, Wunderlich HO. Combined radiotherapy and chemotherapy for treatment of unresectable and or metastatic cancer. Int J Clin Pharmacol. 1974 Jan; 9(1):37-40. PMID: 4593128.
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