Keywords
Last Name
Institution

Colleen A. Hanlon

Title
InstitutionMedical University of South Carolina
DepartmentPsychiatry and Behavioral Sciences
AddressP.O. Box MSC 861
PH537 N
67 President St.
Phone843-792-5732
Fax843-792-5702
vCardDownload vCard

    Collapse Overview 
    Collapse overview
    The overall theme of Dr. Hanlon's scientific research has been to map neural circuit irregularities in substance dependent populations and then modulate these circuits using brain stimulation techniques or neurofeedback. She is leading NIH-funded research directed at 1) longitudinal investigations of neural connectivity in cocaine and alcohol dependent individuals undergoing substance abuse treatment, and 2) developing patient-tailored brain stimulation protocols which may either enhance cognitive control or attenuate craving in treatment seeking individuals. Dr. Hanlon's trainees and collaborators are pioneering non-invasive neuromodulatory strategies for treating addiction including continuous Theta Burst Stimulation to the medial prefrontal cortex, and real-time fMRI biofeedback. Dr. Hanlon has also received independent funding to pursue research in PTSD, Tourette Syndrome, and Stroke rehabilitation. She is dedicated to mentoring graduate students, medical students, medical residents, and other faculty members seeking training in neuroimaging and brain stimulation.

    Collapse keywords
    Drug Studies, Mental Health, Nervous System, Pediatrics, Brain, Movement Disorders, Smoking, Adolescents, Depression, Healthy Volunteer Studies, Pain, Psychiatry, Aging, Alcohol, Central Nervous System, Stroke, Substance Use

    Collapse ORNG Applications 
    Collapse Featured Videos
    Collapse studies/trials

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Philip NS, Sorensen DO, McCalley DM, Hanlon CA. Non-invasive Brain Stimulation for Alcohol Use Disorders: State of the Art and Future Directions. Neurotherapeutics. 2020 Jan; 17(1):116-126. PMID: 31452080.
      View in: PubMed
    2. Hanlon CA, Lench DH, Dowdle LT, Ramos TK. Neural Architecture Influences Repetitive Transcranial Magnetic Stimulation-Induced Functional Change: A Diffusion Tensor Imaging and Functional Magnetic Resonance Imaging Study of Cue-Reactivity Modulation in Alcohol Users. Clin Pharmacol Ther. 2019 Oct; 106(4):702-705. PMID: 31206172.
      View in: PubMed
    3. Ekhtiari H, Tavakoli H, Addolorato G, Baeken C, Bonci A, Campanella S, Castelo-Branco L, Challet-Bouju G, Clark VP, Claus E, Dannon PN, Del Felice A, den Uyl T, Diana M, di Giannantonio M, Fedota JR, Fitzgerald P, Gallimberti L, Grall-Bronnec M, Herremans SC, Herrmann MJ, Jamil A, Khedr E, Kouimtsidis C, Kozak K, Krupitsky E, Lamm C, Lechner WV, Madeo G, Malmir N, Martinotti G, McDonald WM, Montemitro C, Nakamura-Palacios EM, Nasehi M, Noël X, Nosratabadi M, Paulus M, Pettorruso M, Pradhan B, Praharaj SK, Rafferty H, Sahlem G, Salmeron BJ, Sauvaget A, Schluter RS, Sergiou C, Shahbabaie A, Sheffer C, Spagnolo PA, Steele VR, Yuan TF, van Dongen JDM, Van Waes V, Venkatasubramanian G, Verdejo-García A, Verveer I, Welsh JW, Wesley MJ, Witkiewitz K, Yavari F, Zarrindast MR, Zawertailo L, Zhang X, Cha YH, George TP, Frohlich F, Goudriaan AE, Fecteau S, Daughters SB, Stein EA, Fregni F, Nitsche MA, Zangen A, Bikson M, Hanlon CA. Transcranial electrical and magnetic stimulation (tES and TMS) for addiction medicine: A consensus paper on the present state of the science and the road ahead. Neurosci Biobehav Rev. 2019 09; 104:118-140. PMID: 31271802.
      View in: PubMed
    4. Kearney-Ramos TE, Dowdle LT, Mithoefer OJ, Devries W, George MS, Hanlon CA. State-Dependent Effects of Ventromedial Prefrontal Cortex Continuous Thetaburst Stimulation on Cocaine Cue Reactivity in Chronic Cocaine Users. Front Psychiatry. 2019; 10:317. PMID: 31133897.
      View in: PubMed
    5. Dowdle LT, Borckardt JJ, Back SE, Morgan K, Adams D, Madan A, Balliet W, Hanlon CA. Sensitized brain response to acute pain in patients using prescription opiates for chronic pain: A pilot study. Drug Alcohol Depend. 2019 07 01; 200:6-13. PMID: 31071496.
      View in: PubMed
    6. Seo NJ, Lakshminarayanan K, Lauer AW, Ramakrishnan V, Schmit BD, Hanlon CA, George MS, Bonilha L, Downey RJ, DeVries W, Nagy T. Use of imperceptible wrist vibration to modulate sensorimotor cortical activity. Exp Brain Res. 2019 Mar; 237(3):805-816. PMID: 30607471.
      View in: PubMed
    7. Hanlon CA. Treating cue-reactivity with brain stimulation: a new (transdiagnostic) approach. Neuropsychopharmacology. 2019 01; 44(1):232-233. PMID: 30293999.
      View in: PubMed
    8. Adisetiyo V, McGill CE, DeVries WH, Jensen JH, Hanlon CA, Helpern JA. Elevated Brain Iron in Cocaine Use Disorder as Indexed by Magnetic Field Correlation Imaging. Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 06; 4(6):579-588. PMID: 30581153.
      View in: PubMed
    9. Hanlon CA, Shannon EE, Porrino LJ. Brain activity associated with social exclusion overlaps with drug-related frontal-striatal circuitry in cocaine users: A pilot study. Neurobiol Stress. 2019 Feb; 10:100137. PMID: 30937344.
      View in: PubMed
    10. Hanlon CA, Dowdle LT, Gibson NB, Li X, Hamilton S, Canterberry M, Hoffman M. Cortical substrates of cue-reactivity in multiple substance dependent populations: transdiagnostic relevance of the medial prefrontal cortex. Transl Psychiatry. 2018 09 07; 8(1):186. PMID: 30194288.
      View in: PubMed
    11. Hanlon CA, Philip NS, Price RB, Bickel WK, Downar J. A Case for the Frontal Pole as an Empirically Derived Neuromodulation Treatment Target. Biol Psychiatry. 2019 02 01; 85(3):e13-e14. PMID: 30126608.
      View in: PubMed
    12. Hanlon CA, Dowdle LT, Henderson JS. Modulating Neural Circuits with Transcranial Magnetic Stimulation: Implications for Addiction Treatment Development. Pharmacol Rev. 2018 07; 70(3):661-683. PMID: 29945899.
      View in: PubMed
    13. Bell SJ, Lauer A, Lench DH, Hanlon CA. Visual Attention Affects the Amplitude of the Transcranial Magnetic Stimulation-associated Motor-evoked Potential: A Preliminary Study With Clinical Utility. J Psychiatr Pract. 2018 07; 24(4):220-229. PMID: 30427805.
      View in: PubMed
    14. Charalambous CC, Dean JC, Adkins DL, Hanlon CA, Bowden MG. Characterizing the corticomotor connectivity of the bilateral ankle muscles during rest and isometric contraction in healthy adults. J Electromyogr Kinesiol. 2018 Aug; 41:9-18. PMID: 29715530.
      View in: PubMed
    15. Kearney-Ramos TE, Lench DH, Hoffman M, Correia B, Dowdle LT, Hanlon CA. Author Correction: Gray and white matter integrity influence TMS signal propagation: a multimodal evaluation in cocaine-dependent individuals. Sci Rep. 2018 Apr 20; 8(1):6497. PMID: 29679040.
      View in: PubMed
    16. Kearney-Ramos TE, Dowdle LT, Lench DH, Mithoefer OJ, Devries WH, George MS, Anton RF, Hanlon CA. Transdiagnostic Effects of Ventromedial Prefrontal Cortex Transcranial Magnetic Stimulation on Cue Reactivity. Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 07; 3(7):599-609. PMID: 29776789.
      View in: PubMed
    17. Dowdle LT, Brown TR, George MS, Hanlon CA. Single pulse TMS to the DLPFC, compared to a matched sham control, induces a direct, causal increase in caudate, cingulate, and thalamic BOLD signal. Brain Stimul. 2018 Jul - Aug; 11(4):789-796. PMID: 29530447.
      View in: PubMed
    18. Kearney-Ramos TE, Lench DH, Hoffman M, Correia B, Dowdle LT, Hanlon CA. Gray and white matter integrity influence TMS signal propagation: a multimodal evaluation in cocaine-dependent individuals. Sci Rep. 2018 02 19; 8(1):3253. PMID: 29459743.
      View in: PubMed
    19. Hanlon CA, Kearney-Ramos T, Dowdle LT, Hamilton S, DeVries W, Mithoefer O, Austelle C, Lench DH, Correia B, Canterberry M, Smith JP, Brady KT, George MS. Developing Repetitive Transcranial Magnetic Stimulation (rTMS) as a Treatment Tool for Cocaine Use Disorder: a Series of Six Translational Studies. Curr Behav Neurosci Rep. 2017 Dec; 4(4):341-352. PMID: 30009124.
      View in: PubMed
    20. Li X, Sahlem GL, Badran BW, McTeague LM, Hanlon CA, Hartwell KJ, Henderson S, George MS. Transcranial magnetic stimulation of the dorsal lateral prefrontal cortex inhibits medial orbitofrontal activity in smokers. Am J Addict. 2017 Dec; 26(8):788-794. PMID: 28898485.
      View in: PubMed
    21. Hanlon CA, Dowdle LT, Correia B, Mithoefer O, Kearney-Ramos T, Lench D, Griffin M, Anton RF, George MS. Left frontal pole theta burst stimulation decreases orbitofrontal and insula activity in cocaine users and alcohol users. Drug Alcohol Depend. 2017 09 01; 178:310-317. PMID: 28686990.
      View in: PubMed
    22. Summers PM, Hanlon CA. BrainRuler-a free, open-access tool for calculating scalp to cortex distance. Brain Stimul. 2017 Sep - Oct; 10(5):1009-1010. PMID: 28528737.
      View in: PubMed
    23. Lench DH, DeVries W, Hanlon CA. The effect of task difficulty on motor performance and frontal-striatal connectivity in cocaine users. Drug Alcohol Depend. 2017 Apr 01; 173:178-184. PMID: 28260681.
      View in: PubMed
    24. Hanlon C. Blunt or precise? A note about the relative precision of figure-of-eight rTMS coils. Brain Stimul. 2017 Mar - Apr; 10(2):338-339. PMID: 28126249.
      View in: PubMed
    25. Hanlon CA, Dowdle LT, Jones JL. Biomarkers for Success: Using Neuroimaging to Predict Relapse and Develop Brain Stimulation Treatments for Cocaine-Dependent Individuals. Int Rev Neurobiol. 2016; 129:125-56. PMID: 27503451.
      View in: PubMed
    26. Canterberry M, Peltier MR, Brady KT, Hanlon CA. Attenuated neural response to emotional cues in cocaine-dependence: a preliminary analysis of gender differences. Am J Drug Alcohol Abuse. 2016 09; 42(5):577-586. PMID: 27441590.
      View in: PubMed
    27. Hanlon CA, Dowdle LT, Moss H, Canterberry M, George MS. Mobilization of Medial and Lateral Frontal-Striatal Circuits in Cocaine Users and Controls: An Interleaved TMS/BOLD Functional Connectivity Study. Neuropsychopharmacology. 2016 12; 41(13):3032-3041. PMID: 27374278.
      View in: PubMed
    28. Dunlop K, Hanlon CA, Downar J. Noninvasive brain stimulation treatments for addiction and major depression. Ann N Y Acad Sci. 2017 04; 1394(1):31-54. PMID: 26849183.
      View in: PubMed
    29. Mullins CR, Hanlon CA. MAVIN: An Open-Source Tool for Interactive Analysis and Visualization of EMG Data. Brain Stimul. 2016 Mar-Apr; 9(2):305-6. PMID: 26970384.
      View in: PubMed
    30. Hartwell KJ, Hanlon CA, Li X, Borckardt JJ, Canterberry M, Prisciandaro JJ, Moran-Santa Maria MM, LeMatty T, George MS, Brady KT. Individualized real-time fMRI neurofeedback to attenuate craving in nicotine-dependent smokers. J Psychiatry Neurosci. 2016 Jan; 41(1):48-55. PMID: 26505139.
      View in: PubMed
    31. Wesley MJ, Lile JA, Hanlon CA, Porrino LJ. Abnormal medial prefrontal cortex activity in heavy cannabis users during conscious emotional evaluation. Psychopharmacology (Berl). 2016 Mar; 233(6):1035-44. PMID: 26690589.
      View in: PubMed
    32. Bickel WK, Snider SE, Quisenberry AJ, Stein JS, Hanlon CA. Competing neurobehavioral decision systems theory of cocaine addiction: From mechanisms to therapeutic opportunities. Prog Brain Res. 2016; 223:269-93. PMID: 26806781.
      View in: PubMed
    33. Hanlon CA, DeVries W, Dowdle LT, West JA, Siekman B, Li X, George MS. A comprehensive study of sensorimotor cortex excitability in chronic cocaine users: Integrating TMS and functional MRI data. Drug Alcohol Depend. 2015 Dec 01; 157:28-35. PMID: 26541870.
      View in: PubMed
    34. Hanlon CA, Dowdle LT, Austelle CW, DeVries W, Mithoefer O, Badran BW, George MS. What goes up, can come down: Novel brain stimulation paradigms may attenuate craving and craving-related neural circuitry in substance dependent individuals. Brain Res. 2015 Dec 02; 1628(Pt A):199-209. PMID: 25770818.
      View in: PubMed
    35. Williams NR, Taylor JJ, Lamb K, Hanlon CA, Short EB, George MS. Role of functional imaging in the development and refinement of invasive neuromodulation for psychiatric disorders. World J Radiol. 2014 Oct 28; 6(10):756-78. PMID: 25349661.
      View in: PubMed
    36. Hanlon CA, Owens MM, Joseph JE, Zhu X, George MS, Brady KT, Hartwell KJ. Lower subcortical gray matter volume in both younger smokers and established smokers relative to non-smokers. Addict Biol. 2016 Jan; 21(1):185-95. PMID: 25125263.
      View in: PubMed
    37. Hanlon CA, Dowdle LT, Naselaris T, Canterberry M, Cortese BM. Visual cortex activation to drug cues: a meta-analysis of functional neuroimaging papers in addiction and substance abuse literature. Drug Alcohol Depend. 2014 Oct 01; 143:206-12. PMID: 25155889.
      View in: PubMed
    38. Stoeckel LE, Garrison KA, Ghosh S, Wighton P, Hanlon CA, Gilman JM, Greer S, Turk-Browne NB, deBettencourt MT, Scheinost D, Craddock C, Thompson T, Calderon V, Bauer CC, George M, Breiter HC, Whitfield-Gabrieli S, Gabrieli JD, LaConte SM, Hirshberg L, Brewer JA, Hampson M, Van Der Kouwe A, Mackey S, Evins AE. Optimizing real time fMRI neurofeedback for therapeutic discovery and development. Neuroimage Clin. 2014; 5:245-55. PMID: 25161891.
      View in: PubMed
    39. Moran-Santa Maria MM, Hartwell KJ, Hanlon CA, Canterberry M, Lematty T, Owens M, Brady KT, George MS. Right anterior insula connectivity is important for cue-induced craving in nicotine-dependent smokers. Addict Biol. 2015 Mar; 20(2):407-14. PMID: 24529072.
      View in: PubMed
    40. Goldman RL, Canterberry M, Borckardt JJ, Madan A, Byrne TK, George MS, O'Neil PM, Hanlon CA. Executive control circuitry differentiates degree of success in weight loss following gastric-bypass surgery. Obesity (Silver Spring). 2013 Nov; 21(11):2189-2196. PMID: 24136926.
      View in: PubMed
    41. Li X, Malcolm RJ, Huebner K, Hanlon CA, Taylor JJ, Brady KT, George MS, See RE. Low frequency repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex transiently increases cue-induced craving for methamphetamine: a preliminary study. Drug Alcohol Depend. 2013 Dec 01; 133(2):641-6. PMID: 24028801.
      View in: PubMed
    42. Canterberry M, Hanlon CA, Hartwell KJ, Li X, Owens M, LeMatty T, Prisciandaro JJ, Borckardt J, Saladin ME, Brady KT, George MS. Sustained reduction of nicotine craving with real-time neurofeedback: exploring the role of severity of dependence. Nicotine Tob Res. 2013 Dec; 15(12):2120-4. PMID: 23935182.
      View in: PubMed
    43. Hanlon CA, Canterberry M, Taylor JJ, DeVries W, Li X, Brown TR, George MS. Probing the frontostriatal loops involved in executive and limbic processing via interleaved TMS and functional MRI at two prefrontal locations: a pilot study. PLoS One. 2013; 8(7):e67917. PMID: 23874466.
      View in: PubMed
    44. Hanlon CA, Hartwell KJ, Canterberry M, Li X, Owens M, Lematty T, Prisciandaro JJ, Borckardt J, Brady KT, George MS. Reduction of cue-induced craving through realtime neurofeedback in nicotine users: the role of region of interest selection and multiple visits. Psychiatry Res. 2013 Jul 30; 213(1):79-81. PMID: 23683344.
      View in: PubMed
    45. Hanlon CA, Beveridge TJ, Porrino LJ. Recovering from cocaine: insights from clinical and preclinical investigations. Neurosci Biobehav Rev. 2013 Nov; 37(9 Pt A):2037-46. PMID: 23628740.
      View in: PubMed
    46. Li X, Hartwell KJ, Owens M, Lematty T, Borckardt JJ, Hanlon CA, Brady KT, George MS. Repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex reduces nicotine cue craving. Biol Psychiatry. 2013 Apr 15; 73(8):714-20. PMID: 23485014.
      View in: PubMed
    47. Taylor JJ, Borckardt JJ, Canterberry M, Li X, Hanlon CA, Brown TR, George MS. Naloxone-reversible modulation of pain circuitry by left prefrontal rTMS. Neuropsychopharmacology. 2013 Jun; 38(7):1189-97. PMID: 23314221.
      View in: PubMed
    48. Hanlon CA, Canterberry M. The use of brain imaging to elucidate neural circuit changes in cocaine addiction. Subst Abuse Rehabil. 2012 Sep; 3(1):115-128. PMID: 23162375.
      View in: PubMed
    49. Hanlon CA, Jones EM, Li X, Hartwell KJ, Brady KT, George MS. Individual variability in the locus of prefrontal craving for nicotine: implications for brain stimulation studies and treatments. Drug Alcohol Depend. 2012 Oct 01; 125(3):239-43. PMID: 22459915.
      View in: PubMed
    50. Hanlon CA, Dufault DL, Wesley MJ, Porrino LJ. Elevated gray and white matter densities in cocaine abstainers compared to current users. Psychopharmacology (Berl). 2011 Dec; 218(4):681-92. PMID: 21691942.
      View in: PubMed
    51. Hanlon CA, Wesley MJ, Stapleton JR, Laurienti PJ, Porrino LJ. The association between frontal-striatal connectivity and sensorimotor control in cocaine users. Drug Alcohol Depend. 2011 Jun 01; 115(3):240-3. PMID: 21193273.
      View in: PubMed
    52. Wesley MJ, Hanlon CA, Porrino LJ. Poor decision-making by chronic marijuana users is associated with decreased functional responsiveness to negative consequences. Psychiatry Res. 2011 Jan 30; 191(1):51-9. PMID: 21145211.
      View in: PubMed
    53. Hanlon CA, Wesley MJ, Roth AJ, Miller MD, Porrino LJ. Loss of laterality in chronic cocaine users: an fMRI investigation of sensorimotor control. Psychiatry Res. 2010 Jan 30; 181(1):15-23. PMID: 19959345.
      View in: PubMed
    54. Hanlon CA, Wesley MJ, Porrino LJ. Loss of functional specificity in the dorsal striatum of chronic cocaine users. Drug Alcohol Depend. 2009 Jun 01; 102(1-3):88-94. PMID: 19264428.
      View in: PubMed
    55. Beveridge TJ, Gill KE, Hanlon CA, Porrino LJ. Review. Parallel studies of cocaine-related neural and cognitive impairment in humans and monkeys. Philos Trans R Soc Lond B Biol Sci. 2008 Oct 12; 363(1507):3257-66. PMID: 18640916.
      View in: PubMed
    56. Hanlon CA, Buffington AL, McKeown MJ. New brain networks are active after right MCA stroke when moving the ipsilesional arm. Neurology. 2005 Jan 11; 64(1):114-20. PMID: 15642913.
      View in: PubMed
    57. Buffington AL, Hanlon CA, McKeown MJ. Acute and persistent pain modulation of attention-related anterior cingulate fMRI activations. Pain. 2005 Jan; 113(1-2):172-84. PMID: 15621378.
      View in: PubMed
    58. McKeown MJ, Hanlon CA. A post-processing/region of interest (ROI) method for discriminating patterns of activity in statistical maps of fMRI data. J Neurosci Methods. 2004 May 30; 135(1-2):137-47. PMID: 15020098.
      View in: PubMed
    Hanlon's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _