Christiana S. Kappler

Title
InstitutionMedical University of South Carolina
DepartmentReg Med & Cell Bio - Administration
AddressP.O. Box MSC 508
BSB 653
Basic Science Building - 173 Ashley Ave.
Phone843-792-5483
Fax843-876-2299
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ethier SP, Guest ST, Garrett-Mayer E, Armeson K, Wilson RC, Duchinski K, Couch D, Gray JW, Kappler C. Development and implementation of the SUM breast cancer cell line functional genomics knowledge base. NPJ Breast Cancer. 2020; 6:30. PMID: 32715085.
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    2. Giordano A, Liu Y, Armeson K, Park Y, Ridinger M, Erlander M, Reuben J, Britten C, Kappler C, Yeh E, Ethier S. Polo-like kinase 1 (Plk1) inhibition synergizes with taxanes in triple negative breast cancer. PLoS One. 2019; 14(11):e0224420. PMID: 31751384.
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    3. Irish JC, Mills JN, Turner-Ivey B, Wilson RC, Guest ST, Rutkovsky A, Dombkowski A, Kappler CS, Hardiman G, Ethier SP. Amplification of WHSC1L1 regulates expression and estrogen-independent activation of ERa in SUM-44 breast cancer cells and is associated with ERa over-expression in breast cancer. Mol Oncol. 2016 06; 10(6):850-65. PMID: 27005559.
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    4. Kappler CS, Guest ST, Irish JC, Garrett-Mayer E, Kratche Z, Wilson RC, Ethier SP. Oncogenic signaling in amphiregulin and EGFR-expressing PTEN-null human breast cancer. Mol Oncol. 2015 Feb; 9(2):527-43. PMID: 25454348.
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    5. Turner-Ivey B, Guest ST, Irish JC, Kappler CS, Garrett-Mayer E, Wilson RC, Ethier SP. KAT6A, a chromatin modifier from the 8p11-p12 amplicon is a candidate oncogene in luminal breast cancer. Neoplasia. 2014 Aug; 16(8):644-55. PMID: 25220592.
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    6. Xu L, Kappler CS, Mani SK, Shepherd NR, Renaud L, Snider P, Conway SJ, Menick DR. Chronic administration of KB-R7943 induces up-regulation of cardiac NCX1. J Biol Chem. 2009 Oct 02; 284(40):27265-72. PMID: 19661061.
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    7. Menick DR, Renaud L, Buchholz A, Müller JG, Zhou H, Kappler CS, Kubalak SW, Conway SJ, Xu L. Regulation of Ncx1 gene expression in the normal and hypertrophic heart. Ann N Y Acad Sci. 2007 Mar; 1099:195-203. PMID: 17446459.
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    8. Xu L, Renaud L, Müller JG, Baicu CF, Bonnema DD, Zhou H, Kappler CS, Kubalak SW, Zile MR, Conway SJ, Menick DR. Regulation of Ncx1 expression. Identification of regulatory elements mediating cardiac-specific expression and up-regulation. J Biol Chem. 2006 Nov 10; 281(45):34430-40. PMID: 16966329.
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    9. Xu L, Kappler CS, Menick DR. The role of p38 in the regulation of Na+-Ca2+ exchanger expression in adult cardiomyocytes. J Mol Cell Cardiol. 2005 May; 38(5):735-43. PMID: 15850567.
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    10. Xu L, Muller JG, Withers PR, Kappler C, Jiang W, Menick DR. Role of MAP kinases in the Na+/Ca2+ exchanger gene expression in feline adult cardiocytes. Ann N Y Acad Sci. 2002 Nov; 976:285-7. PMID: 12502571.
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    11. Müller JG, Isomatsu Y, Koushik SV, O'Quinn M, Xu L, Kappler CS, Hapke E, Zile MR, Conway SJ, Menick DR. Cardiac-specific expression and hypertrophic upregulation of the feline Na(+)-Ca(2+) exchanger gene H1-promoter in a transgenic mouse model. Circ Res. 2002 Feb 08; 90(2):158-64. PMID: 11834708.
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