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Last Name
Institution

Charlie B. Strange

Title
InstitutionMedical University of South Carolina
DepartmentPulmonary
AddressP.O. Box MSC 630
Clinical Science Bldg. - 96 Jonathan Lucas St.
Phone843-792-3174
Fax843-876-2057
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    Collapse Overview 
    Collapse overview
    Dr. Charlie Strange is a Professor of Pulmonary and Critical Care Medicine at MUSC with faculty appointments in the Department of Medicine and the Department of Graduate Studies. His clinical interests include chronic obstructive pulmonary disease (with specialty interest in alpha-1 antitrypsin deficiency and bronchoscopic lung volume reduction) and interstitial lung disease (with specialty interest in the connective tissue diseases).


    Dr. Strange has interest in rare lung diseases and participates in NIH programs to advance their treatment. He is the Principal Investigator for the Alpha-1 Foundation Research Registry, the largest registry of individuals with alpha-1 antitrypsin deficiency or the carrier state in the world. The Registry is used to support research on new therapies, genetic linkage studies, and social sciences research. The Alpha Coded Testing (ACT) study provides confidential testing for alpha-1 antitrypsin deficiency.


    Dr. Strange is available for physician consultations on the above research studies and continues active inpatient and outpatient clinical service. For this activity and teaching he has been listed in “Best Doctors in America” 2003-2015 for General Pulmonary and Critical Care Medicine, Interstitial Lung Diseases, and Chronic Obstructive Pulmonary Disease.

    Collapse keywords
    Liver, Pulmonary, Pulmonary Arterial Hypertension (PAH), Rare Diseases, Environmental Factors, Lung, Genetics, Shortness of Breath, Asthma, Breathing

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Lal C, Strange C. Evaluating fluticasone furoate + vilanterol for the treatment of chronic obstructive pulmonary disease (COPD). Expert Opin Pharmacother. 2019 Jun; 20(9):1075-1085. PMID: 30983423.
      View in: PubMed
    2. Gupta N, Lee HS, Young LR, Strange C, Moss J, Singer LG, Nakata K, Barker AF, Chapman JT, Brantly ML, Stocks JM, Brown KK, Lynch JP, Goldberg HJ, Downey GP, Taveira-DaSilva AM, Krischer JP, Setchell K, Trapnell BC, Inoue Y, McCormack FX. Analysis of the MILES cohort reveals determinants of disease progression and treatment response in lymphangioleiomyomatosis. Eur Respir J. 2019 Apr; 53(4). PMID: 30846465.
      View in: PubMed
    3. Strange C. Rare Disease Registries: Steps Forward. Chronic Obstr Pulm Dis. 2019 Apr; 6(2):126-128. PMID: 31063275.
      View in: PubMed
    4. Serban KA, Mikosz A, Strange C, Janciauskiene SM, Stolk J, Jonigk D, Sandhaus RA, Petrache I. Lectin Complement Pathway in Emphysema. Am J Respir Crit Care Med. 2019 Mar 01; 199(5):659-661. PMID: 30557515.
      View in: PubMed
    5. Slebos DJ, Cicenia J, Sciurba FC, Criner GJ, Hartman JE, Garner J, Deslée G, Delage A, Jantz M, Marquette CH, Strange C, Hatipoglu U, Mehta AC, LaPrad AS, Schmid-Bindert G, Herth FJF, Shah PL. Predictors of Response to Endobronchial Coil Therapy in Patients With Advanced Emphysema. Chest. 2019 May; 155(5):928-937. PMID: 30797746.
      View in: PubMed
    6. Pleasants RA, Heidari K, Ohar J, Donohue JF, Lugogo N, Richard CL, Kanotra S, Mannino DM, Kraft M, Liao W, Strange C. Use of a Cross-Sectional Survey in the Adult Population to Characterize Persons at High-Risk for Chronic Obstructive Pulmonary Disease. Healthcare (Basel). 2019 Jan 18; 7(1). PMID: 30669305.
      View in: PubMed
    7. Foil KE, Blanton MG, Sanders C, Kim J, Al Ashry HS, Kumbhare S, Strange C. Sequencing Alpha-1 MZ Individuals Shows Frequent Biallelic Mutations. Pulm Med. 2018; 2018:2836389. PMID: 30254761.
      View in: PubMed
    8. Garand KL, Strange C, Paoletti L, Hopkins-Rossabi T, Martin-Harris B. Oropharyngeal swallow physiology and swallowing-related quality of life in underweight patients with concomitant advanced chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2018; 13:2663-2671. PMID: 30214184.
      View in: PubMed
    9. Tashkin DP, Strange C. Inhaled corticosteroids for chronic obstructive pulmonary disease: what is their role in therapy? Int J Chron Obstruct Pulmon Dis. 2018; 13:2587-2601. PMID: 30214177.
      View in: PubMed
    10. Lal C, Hardiman G, Kumbhare S, Strange C. Proteomic biomarkers of cognitive impairment in obstructive sleep apnea syndrome. Sleep Breath. 2019 Mar; 23(1):251-257. PMID: 29968150.
      View in: PubMed
    11. Wang M, Song L, Strange C, Dong X, Wang H. Therapeutic Effects of Adipose Stem Cells from Diabetic Mice for the Treatment of Type 2 Diabetes. Mol Ther. 2018 08 01; 26(8):1921-1930. PMID: 30005867.
      View in: PubMed
    12. Strange C. Anti-Proteases and Alpha-1 Antitrypsin Augmentation Therapy. Respir Care. 2018 Jun; 63(6):690-698. PMID: 29794204.
      View in: PubMed
    13. Kumbhare S, Strange C. Mortality in Asthma-Chronic Obstructive Pulmonary Disease Overlap in the United States. South Med J. 2018 05; 111(5):293-298. PMID: 29767222.
      View in: PubMed
    14. Wang H, Strange C, Nietert PJ, Wang J, Turnbull TL, Cloud C, Owczarski S, Shuford B, Duke T, Gilkeson G, Luttrell L, Hermayer K, Fernandes J, Adams DB, Morgan KA. Autologous Mesenchymal Stem Cell and Islet Cotransplantation: Safety and Efficacy. Stem Cells Transl Med. 2018 Jan; 7(1):11-19. PMID: 29159905.
      View in: PubMed
    15. Lal C, Strange C. A review of current and developing fixed-dose LABA/LAMA combinations for treating COPD. Expert Opin Pharmacother. 2017 Dec; 18(17):1833-1843. PMID: 29115881.
      View in: PubMed
    16. Gupta N, Finlay GA, Kotloff RM, Strange C, Wilson KC, Young LR, Taveira-DaSilva AM, Johnson SR, Cottin V, Sahn SA, Ryu JH, Seyama K, Inoue Y, Downey GP, Han MK, Colby TV, Wikenheiser-Brokamp KA, Meyer CA, Smith K, Moss J, McCormack FX. Lymphangioleiomyomatosis Diagnosis and Management: High-Resolution Chest Computed Tomography, Transbronchial Lung Biopsy, and Pleural Disease Management. An Official American Thoracic Society/Japanese Respiratory Society Clinical Practice Guideline. Am J Respir Crit Care Med. 2017 11 15; 196(10):1337-1348. PMID: 29140122.
      View in: PubMed
    17. Kanaan R, Strange C. Use of multitarget tyrosine kinase inhibitors to attenuate platelet-derived growth factor signalling in lung disease. Eur Respir Rev. 2017 Dec 31; 26(146). PMID: 29070579.
      View in: PubMed
    18. Al Ashry HS, Strange C. COPD in individuals with the PiMZ alpha-1 antitrypsin genotype. Eur Respir Rev. 2017 Dec 31; 26(146). PMID: 29070580.
      View in: PubMed
    19. Song L, Sun Z, Kim DS, Gou W, Strange C, Dong H, Cui W, Gilkeson G, Morgan KA, Adams DB, Wang H. Adipose stem cells from chronic pancreatitis patients improve mouse and human islet survival and function. Stem Cell Res Ther. 2017 08 30; 8(1):192. PMID: 28854965.
      View in: PubMed
    20. Sun Z, Gou W, Kim DS, Dong X, Strange C, Tan Y, Adams DB, Wang H. Adipose Stem Cell Therapy Mitigates Chronic Pancreatitis via Differentiation into Acinar-like Cells in Mice. Mol Ther. 2017 11 01; 25(11):2490-2501. PMID: 28784560.
      View in: PubMed
    21. Argula RG, Karwa A, Lauer A, Gregg D, Silver RM, Feghali-Bostwick C, Schanpp LM, Egbert K, Usher BW, Ramakrishnan V, Hassoun PM, Strange C. Differences in Right Ventricular Functional Changes during Treatment between Systemic Sclerosis-associated Pulmonary Arterial Hypertension and Idiopathic Pulmonary Arterial Hypertension. Ann Am Thorac Soc. 2017 May; 14(5):682-689. PMID: 28282243.
      View in: PubMed
    22. Wang J, Sun Z, Gou W, Adams DB, Cui W, Morgan KA, Strange C, Wang H. a-1 Antitrypsin Enhances Islet Engraftment by Suppression of Instant Blood-Mediated Inflammatory Reaction. Diabetes. 2017 04; 66(4):970-980. PMID: 28069642.
      View in: PubMed
    23. Lal C, Strange C. Spotlight on fluticasone furoate/umeclidinium/vilanterol in COPD: design, development, and potential place in therapy. Int J Chron Obstruct Pulmon Dis. 2017; 12:135-140. PMID: 28115838.
      View in: PubMed
    24. McCormack FX, Gupta N, Finlay GR, Young LR, Taveira-DaSilva AM, Glasgow CG, Steagall WK, Johnson SR, Sahn SA, Ryu JH, Strange C, Seyama K, Sullivan EJ, Kotloff RM, Downey GP, Chapman JT, Han MK, D'Armiento JM, Inoue Y, Henske EP, Bissler JJ, Colby TV, Kinder BW, Wikenheiser-Brokamp KA, Brown KK, Cordier JF, Meyer C, Cottin V, Brozek JL, Smith K, Wilson KC, Moss J. Official American Thoracic Society/Japanese Respiratory Society Clinical Practice Guidelines: Lymphangioleiomyomatosis Diagnosis and Management. Am J Respir Crit Care Med. 2016 09 15; 194(6):748-61. PMID: 27628078.
      View in: PubMed
    25. Tashkin DP, Roth MD, Clements PJ, Furst DE, Khanna D, Kleerup EC, Goldin J, Arriola E, Volkmann ER, Kafaja S, Silver R, Steen V, Strange C, Wise R, Wigley F, Mayes M, Riley DJ, Hussain S, Assassi S, Hsu VM, Patel B, Phillips K, Martinez F, Golden J, Connolly MK, Varga J, Dematte J, Hinchcliff ME, Fischer A, Swigris J, Meehan R, Theodore A, Simms R, Volkov S, Schraufnagel DE, Scholand MB, Frech T, Molitor JA, Highland K, Read CA, Fritzler MJ, Kim GHJ, Tseng CH, Elashoff RM. Mycophenolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease (SLS II): a randomised controlled, double-blind, parallel group trial. Lancet Respir Med. 2016 09; 4(9):708-719. PMID: 27469583.
      View in: PubMed
    26. Shah PL, Gompelmann D, Valipour A, McNulty WH, Eberhardt R, Grah C, Egan J, Ficker JH, Wagner M, Witt C, Liebers U, Hopkins P, Gesierich W, Phillips M, Stanzel F, Petermann C, Strange C, Snell G, Herth FJF. Thermal vapour ablation to reduce segmental volume in patients with severe emphysema: STEP-UP 12 month results. Lancet Respir Med. 2016 09; 4(9):e44-e45. PMID: 27451345.
      View in: PubMed
    27. Strange C, Kumbhare S. Reply: Asthma/COPD Overlap Syndrome and Medicare 30-Day Readmissions. Ann Am Thorac Soc. 2016 07; 13(7):1192. PMID: 27388414.
      View in: PubMed
    28. Sandhaus RA, Turino G, Brantly ML, Campos M, Cross CE, Goodman K, Hogarth DK, Knight SL, Stocks JM, Stoller JK, Strange C, Teckman J. The Diagnosis and Management of Alpha-1 Antitrypsin Deficiency in the Adult. Chronic Obstr Pulm Dis. 2016 06 06; 3(3):668-682. PMID: 28848891.
      View in: PubMed
    29. Kumbhare S, Pleasants R, Ohar JA, Strange C. Characteristics and Prevalence of Asthma/Chronic Obstructive Pulmonary Disease Overlap in the United States. Ann Am Thorac Soc. 2016 06; 13(6):803-10. PMID: 26974689.
      View in: PubMed
    30. Sciurba FC, Criner GJ, Strange C, Shah PL, Michaud G, Connolly TA, Deslée G, Tillis WP, Delage A, Marquette CH, Krishna G, Kalhan R, Ferguson JS, Jantz M, Maldonado F, McKenna R, Majid A, Rai N, Gay S, Dransfield MT, Angel L, Maxfield R, Herth FJ, Wahidi MM, Mehta A, Slebos DJ. Effect of Endobronchial Coils vs Usual Care on Exercise Tolerance in Patients With Severe Emphysema: The RENEW Randomized Clinical Trial. JAMA. 2016 May 24-31; 315(20):2178-89. PMID: 27179849.
      View in: PubMed
    31. Wheaton AG, Pleasants RA, Croft JB, Ohar JA, Heidari K, Mannino DM, Liu Y, Strange C. Gender and asthma-chronic obstructive pulmonary disease overlap syndrome. J Asthma. 2016 09; 53(7):720-31. PMID: 27043854.
      View in: PubMed
    32. Kumbhare SD, Beiko T, Wilcox SR, Strange C. Characteristics of COPD Patients Using United States Emergency Care or Hospitalization. Chronic Obstr Pulm Dis. 2016 Mar 28; 3(2):539-548. PMID: 28848878.
      View in: PubMed
    33. Davis JR, Kern DM, Williams SA, Tunceli O, Wu B, Hollis S, Strange C, Trudo F. Health Care Utilization and Costs After Initiating Budesonide/Formoterol Combination or Fluticasone/Salmeterol Combination Among COPD Patients New to ICS/LABA Treatment. J Manag Care Spec Pharm. 2016 Mar; 22(3):293-304. PMID: 27003559.
      View in: PubMed
    34. Argula RG, Kokosi M, Lo P, Kim HJ, Ravenel JG, Meyer C, Goldin J, Lee HS, Strange C, McCormack FX. A Novel Quantitative Computed Tomographic Analysis Suggests How Sirolimus Stabilizes Progressive Air Trapping in Lymphangioleiomyomatosis. Ann Am Thorac Soc. 2016 Mar; 13(3):342-9. PMID: 26799509.
      View in: PubMed
    35. Panagiotou M, Polychronopoulos V, Strange C. Respiratory and lower limb muscle function in interstitial lung disease. Chron Respir Dis. 2016 May; 13(2):162-72. PMID: 26768011.
      View in: PubMed
    36. Sebaaly J, Bowers L, Mazur J, Kotloff R, Olmsted BR, Kaplan A, Strange C. Rapid oral desensitization to sirolimus in a patient with lymphangioleiomyomatosis. J Allergy Clin Immunol Pract. 2016 Mar-Apr; 4(2):352-3. PMID: 26725158.
      View in: PubMed
    37. Valipour A, Shah PL, Gesierich W, Eberhardt R, Snell G, Strange C, Barry R, Gupta A, Henne E, Bandyopadhyay S, Raffy P, Yin Y, Tschirren J, Herth FJ. Patterns of Emphysema Heterogeneity. Respiration. 2015; 90(5):402-11. PMID: 26430783.
      View in: PubMed
    38. Strange C, Senior RM, Sciurba F, O'Neal S, Morris A, Wisniewski SR, Bowler R, Hochheiser HS, Becich MJ, Zhang Y, Leader JK, Methé BA, Kaminski N, Sandhaus RA. Rationale and Design of the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis Study. Alpha-1 Protocol. Ann Am Thorac Soc. 2015 Oct; 12(10):1551-60. PMID: 26153726.
      View in: PubMed
    39. Trudo F, Kern DM, Davis JR, Tunceli O, Zhou S, Graham EL, Strange C, Williams SA. Comparative effectiveness of budesonide/formoterol combination and tiotropium bromide among COPD patients new to these controller treatments. Int J Chron Obstruct Pulmon Dis. 2015; 10:2055-66. PMID: 26451101.
      View in: PubMed
    40. Lal C, DiBartolo MM, Kumbhare S, Strange C, Joseph JE. Impact of obstructive sleep apnea syndrome on cognition in early postmenopausal women. Sleep Breath. 2016 May; 20(2):621-6. PMID: 26385776.
      View in: PubMed
    41. Pleasants RA, Heidari K, Wheaton AG, Ohar JA, Strange C, Croft JB, Liao W, Mannino DM, Kraft M. Targeting Persons With or At High Risk for Chronic Obstructive Pulmonary Disease by State-based Surveillance. COPD. 2015; 12(6):680-9. PMID: 26367193.
      View in: PubMed
    42. Strange C, Beiko T. Treatment of Alpha-1 Antitrypsin Deficiency. Semin Respir Crit Care Med. 2015 Aug; 36(4):470-7. PMID: 26238635.
      View in: PubMed
    43. Kern DM, Davis J, Williams SA, Tunceli O, Wu B, Hollis S, Strange C, Trudo F. Validation of an administrative claims-based diagnostic code for pneumonia in a US-based commercially insured COPD population. Int J Chron Obstruct Pulmon Dis. 2015; 10:1417-25. PMID: 26229461.
      View in: PubMed
    44. Liu Y, Pleasants RA, Croft JB, Wheaton AG, Heidari K, Malarcher AM, Ohar JA, Kraft M, Mannino DM, Strange C. Smoking duration, respiratory symptoms, and COPD in adults aged =45 years with a smoking history. Int J Chron Obstruct Pulmon Dis. 2015; 10:1409-16. PMID: 26229460.
      View in: PubMed
    45. Liu Y, Pleasants RA, Croft JB, Lugogo N, Ohar J, Heidari K, Strange C, Wheaton AG, Mannino DM, Kraft M. Body mass index, respiratory conditions, asthma, and chronic obstructive pulmonary disease. Respir Med. 2015 Jul; 109(7):851-9. PMID: 26006753.
      View in: PubMed
    46. Strange C, Monk R, Schwarz L, Walker D, Kumbhare S, Bieko T. The United States Alpha-1 Foundation Research Registry: Genesis, Impact and Future. COPD. 2015 May; 12 Suppl 1:42-5. PMID: 25938291.
      View in: PubMed
    47. Lo P, Brown MS, Kim H, Kim H, Argula R, Strange C, Goldin JG. Cyst-based measurements for assessing lymphangioleiomyomatosis in computed tomography. Med Phys. 2015 May; 42(5):2287-95. PMID: 25979023.
      View in: PubMed
    48. Wanner A, Groft SC, Teagarden JR, Krischer J, Davis BR, Coffey CS, Hickam DH, Teckman J, Nelson DR, McCaleb ML, Loomba R, Strange C, Sandhaus RA, Brantly M, Edelman JM, Farrugia A. Clinical Trial Design for Alpha-1 Antitrypsin Deficiency: A Model for Rare Diseases. Chronic Obstr Pulm Dis. 2015 Apr 28; 2(2):177-190. PMID: 28848840.
      View in: PubMed
    49. Kern DM, Davis J, Williams SA, Tunceli O, Wu B, Hollis S, Strange C, Trudo F. Comparative effectiveness of budesonide/formoterol combination and fluticasone/salmeterol combination among chronic obstructive pulmonary disease patients new to controller treatment: a US administrative claims database study. Respir Res. 2015 Apr 23; 16:52. PMID: 25899176.
      View in: PubMed
    50. Hoth KF, Wamboldt FS, Ford DW, Sandhaus RA, Strange C, Bekelman DB, Holm KE. The social environment and illness uncertainty in chronic obstructive pulmonary disease. Int J Behav Med. 2015 Apr; 22(2):223-32. PMID: 25008041.
      View in: PubMed
    51. Pastis NJ, Strange CB. Counterpoint: Should nurse practitioners perform transbronchial biopsies? No. Chest. 2015 Mar; 147(3):596-7. PMID: 25732442.
      View in: PubMed
    52. Pastis NJ, Strange CB. Rebuttal from Drs Pastis and Strange. Chest. 2015 Mar; 147(3):598-9. PMID: 25732444.
      View in: PubMed
    53. Lal C, Strange C. Aclidinium bromide plus formoterol for the treatment of chronic obstructive pulmonary disease. Expert Opin Pharmacother. 2015 Feb; 16(3):427-34. PMID: 25597386.
      View in: PubMed
    54. Lal C, Siddiqi N, Kumbhare S, Strange C. Impact of medications on cognitive function in obstructive sleep apnea syndrome. Sleep Breath. 2015 Sep; 19(3):939-45. PMID: 25566945.
      View in: PubMed
    55. Bandyopadhyay S, Henne E, Gupta A, Barry R, Snell G, Strange C, Herth FJ. Segmental approach to lung volume reduction therapy for emphysema patients. Respiration. 2015; 89(1):76-81. PMID: 25500669.
      View in: PubMed
    56. Bade BC, Strange C, Lal C. Effect of obstructive sleep apnea treatment on mail-in cognitive function screening instrument. Am J Med Sci. 2014 Sep; 348(3):215-8. PMID: 24736766.
      View in: PubMed
    57. Tan L, Dickens JA, Demeo DL, Miranda E, Perez J, Rashid ST, Day J, Ordoñez A, Marciniak SJ, Haq I, Barker AF, Campbell EJ, Eden E, McElvaney NG, Rennard SI, Sandhaus RA, Stocks JM, Stoller JK, Strange C, Turino G, Rouhani FN, Brantly M, Lomas DA. Circulating polymers in a1-antitrypsin deficiency. Eur Respir J. 2014 May; 43(5):1501-4. PMID: 24603821.
      View in: PubMed
    58. Williams PH, Shore L, Sineath M, Quill J, Warner B, Keith J, Walker D, Wienke S, Flavin S, Strange C. Genetics' influence on patient experiences with a rare chronic disorder: a photovoice study of living with alpha-1 antitrypsin deficiency. Nurs Clin North Am. 2013 Dec; 48(4):627-36. PMID: 24295190.
      View in: PubMed
    59. Argula RG, Strange C, Ramakrishnan V, Goldin J. Baseline regional perfusion impacts exercise response to endobronchial valve therapy in advanced pulmonary emphysema. Chest. 2013 Nov; 144(5):1578-1586. PMID: 23828481.
      View in: PubMed
    60. Stoller JK, Strange C, Schwarz L, Kallstrom TJ, Chatburn RL. Detection of alpha-1 antitrypsin deficiency by respiratory therapists: experience with an educational program. Respir Care. 2014 May; 59(5):667-72. PMID: 24106322.
      View in: PubMed
    61. Wienke S, Brown K, Farmer M, Strange C. Expanded carrier screening panels-does bigger mean better? J Community Genet. 2014 Apr; 5(2):191-8. PMID: 24062228.
      View in: PubMed
    62. Young L, Lee HS, Inoue Y, Moss J, Singer LG, Strange C, Nakata K, Barker AF, Chapman JT, Brantly ML, Stocks JM, Brown KK, Lynch JP, Goldberg HJ, Downey GP, Swigris JJ, Taveira-DaSilva AM, Krischer JP, Trapnell BC, McCormack FX. Serum VEGF-D a concentration as a biomarker of lymphangioleiomyomatosis severity and treatment response: a prospective analysis of the Multicenter International Lymphangioleiomyomatosis Efficacy of Sirolimus (MILES) trial. Lancet Respir Med. 2013 Aug; 1(6):445-52. PMID: 24159565.
      View in: PubMed
    63. Campos MA, Kueppers F, Stocks JM, Strange C, Chen J, Griffin R, Wang-Smith L, Brantly ML. Safety and pharmacokinetics of 120 mg/kg versus 60 mg/kg weekly intravenous infusions of alpha-1 proteinase inhibitor in alpha-1 antitrypsin deficiency: a multicenter, randomized, double-blind, crossover study (SPARK). COPD. 2013 Dec; 10(6):687-95. PMID: 23862647.
      View in: PubMed
    64. Hoth KF, Wamboldt FS, Strand M, Ford DW, Sandhaus RA, Strange C, Bekelman DB, Holm KE. Prospective impact of illness uncertainty on outcomes in chronic lung disease. Health Psychol. 2013 Nov; 32(11):1170-4. PMID: 23772888.
      View in: PubMed
    65. Holm KE, Plaufcan MR, Ford DW, Sandhaus RA, Strand M, Strange C, Wamboldt FS. The impact of age on outcomes in chronic obstructive pulmonary disease differs by relationship status. J Behav Med. 2014 Aug; 37(4):654-63. PMID: 23645147.
      View in: PubMed
    66. Holm KE, Borson S, Sandhaus RA, Ford DW, Strange C, Bowler RP, Make BJ, Wamboldt FS. Differences in adjustment between individuals with alpha-1 antitrypsin deficiency (AATD)-associated COPD and non-AATD COPD. COPD. 2013 Apr; 10(2):226-34. PMID: 23547634.
      View in: PubMed
    67. Monk R, Graves M, Williams P, Strange C. Inhaled alpha 1-antitrypsin: gauging patient interest in a new treatment. COPD. 2013 Aug; 10(4):411-5. PMID: 23537112.
      View in: PubMed
    68. Strange C. Airway disease in alpha-1 antitrypsin deficiency. COPD. 2013 Mar; 10 Suppl 1:68-73. PMID: 23528021.
      View in: PubMed
    69. Holm KE, Wamboldt FS, Ford DW, Sandhaus RA, Strand M, Strange C, Hoth KF. The prospective association of perceived criticism with dyspnea in chronic lung disease. J Psychosom Res. 2013 May; 74(5):450-3. PMID: 23597335.
      View in: PubMed
    70. Argula RG, Strange C, Budisavljevic MN. Multiorgan system dysfunction in the chylomicronemia syndrome. J Intensive Care Med. 2014 May-Jun; 29(3):175-8. PMID: 23753228.
      View in: PubMed
    71. Baughman RP, Meyer KC, Nathanson I, Angel L, Bhorade SM, Chan KM, Culver D, Harrod CG, Hayney MS, Highland KB, Limper AH, Patrick H, Strange C, Whelan T. Monitoring of nonsteroidal immunosuppressive drugs in patients with lung disease and lung transplant recipients: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2012 Nov; 142(5):e1S-e111S. PMID: 23131960.
      View in: PubMed
    72. Baughman RP, Meyer KC, Nathanson I, Angel L, Bhorade SM, Chan KM, Culver D, Harrod CG, Hayney MS, Highland KB, Limper AH, Patrick H, Strange C, Whelan T. Executive summary: monitoring of nonsteroidal immunosuppressive drugs in patients with lung disease and lung transplant recipients: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2012 Nov; 142(5):1284-1288. PMID: 23131936.
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    73. Bains SN, Bains SS, Anis M, Strange C, Mohr LC. Rude awakening: acute abdominal pain with spontaneous resolution. Am J Med. 2012 Oct; 125(10):971-3. PMID: 22884177.
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    74. Siedlinski M, Klanderman B, Sandhaus RA, Barker AF, Brantly ML, Eden E, McElvaney NG, Rennard SI, Stocks JM, Stoller JK, Strange C, Turino GM, Campbell EJ, Demeo DL. Association of cigarette smoking and CRP levels with DNA methylation in a-1 antitrypsin deficiency. Epigenetics. 2012 Jul; 7(7):720-8. PMID: 22617718.
      View in: PubMed
    75. Lal C, Strange C, Bachman D. Neurocognitive impairment in obstructive sleep apnea. Chest. 2012 Jun; 141(6):1601-1610. PMID: 22670023.
      View in: PubMed
    76. Hoth KF, Ford DW, Sandhaus RA, Strange C, Wamboldt FS, Holm KE. Alcohol use predicts ER visits in individuals with alpha-1 antitrypsin deficiency (AATD) associated COPD. COPD. 2012 Aug; 9(4):417-25. PMID: 22651849.
      View in: PubMed
    77. Meyer KC, Raghu G, Baughman RP, Brown KK, Costabel U, du Bois RM, Drent M, Haslam PL, Kim DS, Nagai S, Rottoli P, Saltini C, Selman M, Strange C, Wood B. An official American Thoracic Society clinical practice guideline: the clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease. Am J Respir Crit Care Med. 2012 May 01; 185(9):1004-14. PMID: 22550210.
      View in: PubMed
    78. Rahaghi FF, Sandhaus RA, Brantly ML, Rouhani F, Campos MA, Strange C, Hogarth DK, Eden E, Stocks JM, Krowka MJ, Stoller JK. The prevalence of alpha-1 antitrypsin deficiency among patients found to have airflow obstruction. COPD. 2012 Aug; 9(4):352-8. PMID: 22506682.
      View in: PubMed
    79. Brown MS, Kim HJ, Abtin FG, Strange C, Galperin-Aizenberg M, Pais R, Da Costa IG, Ordookhani A, Chong D, Ni C, McNitt-Gray MF, Tashkin DP, Goldin JG. Emphysema lung lobe volume reduction: effects on the ipsilateral and contralateral lobes. Eur Radiol. 2012 Jul; 22(7):1547-55. PMID: 22466511.
      View in: PubMed
    80. Kim WJ, Wood AM, Barker AF, Brantly ML, Campbell EJ, Eden E, McElvaney G, Rennard SI, Sandhaus RA, Stocks JM, Stoller JK, Strange C, Turino G, Silverman EK, Stockley RA, Demeo DL. Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency. Respir Res. 2012 Feb 22; 13:16. PMID: 22356581.
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    81. Furst DE, Tseng CH, Clements PJ, Strange C, Tashkin DP, Roth MD, Khanna D, Li N, Elashoff R, Schraufnagel DE. Adverse events during the Scleroderma Lung Study. Am J Med. 2011 May; 124(5):459-67. PMID: 21531236.
      View in: PubMed
    82. Lal C, Barker J, Strange C. Unilateral pulmonary artery aplasia in a pregnant patient. Case Rep Med. 2011; 2011:806723. PMID: 21547212.
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    83. McGee D, Strange C, McClure R, Schwarz L, Erven M. The Alpha-1 Association Genetic Counseling Program: an innovative approach to service. J Genet Couns. 2011 Aug; 20(4):330-6. PMID: 21424325.
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    84. McCormack FX, Inoue Y, Moss J, Singer LG, Strange C, Nakata K, Barker AF, Chapman JT, Brantly ML, Stocks JM, Brown KK, Lynch JP, Goldberg HJ, Young LR, Kinder BW, Downey GP, Sullivan EJ, Colby TV, McKay RT, Cohen MM, Korbee L, Taveira-DaSilva AM, Lee HS, Krischer JP, Trapnell BC. Efficacy and safety of sirolimus in lymphangioleiomyomatosis. N Engl J Med. 2011 Apr 28; 364(17):1595-606. PMID: 21410393.
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    85. Lal C, Strange C. Is systemic sclerosis interstitial lung disease slowly progressive? J Bras Pneumol. 2011 Mar-Apr; 37(2):142-3. PMID: 21537648.
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    86. Strange C. COPD and lung cancer: are they both airways diseases? Chest. 2010 Dec; 138(6):1289-90. PMID: 21138878.
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    87. Stocks JM, Brantly ML, Wang-Smith L, Campos MA, Chapman KR, Kueppers F, Sandhaus RA, Strange C, Turino G. Pharmacokinetic comparability of Prolastin®-C to Prolastin® in alpha1-antitrypsin deficiency: a randomized study. BMC Clin Pharmacol. 2010 Sep 30; 10:13. PMID: 20920295.
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    88. Sciurba FC, Ernst A, Herth FJ, Strange C, Criner GJ, Marquette CH, Kovitz KL, Chiacchierini RP, Goldin J, McLennan G. A randomized study of endobronchial valves for advanced emphysema. N Engl J Med. 2010 Sep 23; 363(13):1233-44. PMID: 20860505.
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    89. Kamen DL, Strange C. Pulmonary manifestations of systemic lupus erythematosus. Clin Chest Med. 2010 Sep; 31(3):479-88. PMID: 20692540.
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    90. McGee D, Schwarz L, McClure R, Peterka L, Rouhani F, Brantly M, Strange C. Is PiSS Alpha-1 Antitrypsin Deficiency Associated with Disease? Pulm Med. 2010; 2010:570679. PMID: 21687342.
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    91. Drummond F, Doelken P, Ahmed QA, Gilbert GE, Strange C, Herpel L, Frye MD. Empiric auto-titrating CPAP in people with suspected obstructive sleep apnea. J Clin Sleep Med. 2010 Apr 15; 6(2):140-5. PMID: 20411690.
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    92. Kravitz JN, Strange C. How should we treat vascular and fibrotic lung disease in scleroderma? F1000 Med Rep. 2009 Jul 27; 1. PMID: 20948723.
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    93. Criner GJ, Pinto-Plata V, Strange C, Dransfield M, Gotfried M, Leeds W, McLennan G, Refaely Y, Tewari S, Krasna M, Celli B. Biologic lung volume reduction in advanced upper lobe emphysema: phase 2 results. Am J Respir Crit Care Med. 2009 May 01; 179(9):791-8. PMID: 19179484.
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    94. Garin MC, Highland KB, Silver RM, Strange C. Limitations to the 6-minute walk test in interstitial lung disease and pulmonary hypertension in scleroderma. J Rheumatol. 2009 Feb; 36(2):330-6. PMID: 19208563.
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    95. McLaughlin V, Strange C. Opportunities and challenges in the study of pulmonary arterial hypertension. Am J Respir Crit Care Med. 2009 Jan 15; 179(2):91-2. PMID: 19119151.
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    96. Dickson MR, Carter CL, Carpenter MJ, McClure RL, McGee DA, Zapka JG, Strange C. Barriers to genetic testing among persons at risk for alpha-1 antitrypsin deficiency. Genet Test. 2008 Dec; 12(4):501-5. PMID: 19072562.
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    97. Sandhaus RA, Turino G, Stocks J, Strange C, Trapnell BC, Silverman EK, Everett SE, Stoller JK. alpha1-Antitrypsin augmentation therapy for PI*MZ heterozygotes: a cautionary note. Chest. 2008 Oct; 134(4):831-4. PMID: 18842915.
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    98. Benza RL, Barst RJ, Galie N, Frost A, Girgis RE, Highland KB, Strange C, Black CM, Badesch DB, Rubin L, Fleming TR, Naeije R. Sitaxsentan for the treatment of pulmonary arterial hypertension: a 1-year, prospective, open-label observation of outcome and survival. Chest. 2008 Oct; 134(4):775-82. PMID: 18625676.
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    99. Strange C, Seibold JR. Scleroderma lung disease: "if you don't know where you are going, any road will take you there". Am J Respir Crit Care Med. 2008 Jun 01; 177(11):1178-9. PMID: 18487619.
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    100. Osorio JI, Watkins JM, Strange C, Jenrette JM. Radiation therapy for palliation of Eisenmenger's syndrome-associated painful splenomegaly. Radiat Med. 2008 Feb; 26(2):84-7. PMID: 18301984.
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    101. Kalluri M, Huggins JT, Strange C. A 56-year-old woman with arm pain, dyspnea, and an elevated diaphragm. Chest. 2008 Jan; 133(1):296-9. PMID: 18187758.
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    102. Stoller JK, Fromer L, Brantly M, Stocks J, Strange C. Primary care diagnosis of alpha-1 antitrypsin deficiency: issues and opportunities. Cleve Clin J Med. 2007 Dec; 74(12):869-74. PMID: 18183837.
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    103. Strange C, Bolster MB, Roth MD, Silver RM, Theodore A, Goldin J, Clements P, Chung J, Elashoff RM, Suh R, Smith EA, Furst DE, Tashkin DP. Bronchoalveolar lavage and response to cyclophosphamide in scleroderma interstitial lung disease. Am J Respir Crit Care Med. 2008 Jan 01; 177(1):91-8. PMID: 17901414.
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    104. Tashkin DP, Elashoff R, Clements PJ, Roth MD, Furst DE, Silver RM, Goldin J, Arriola E, Strange C, Bolster MB, Seibold JR, Riley DJ, Hsu VM, Varga J, Schraufnagel D, Theodore A, Simms R, Wise R, Wigley F, White B, Steen V, Read C, Mayes M, Parsley E, Mubarak K, Connolly MK, Golden J, Olman M, Fessler B, Rothfield N, Metersky M, Khanna D, Li N, Li G. Effects of 1-year treatment with cyclophosphamide on outcomes at 2 years in scleroderma lung disease. Am J Respir Crit Care Med. 2007 Nov 15; 176(10):1026-34. PMID: 17717203.
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    105. Demeo DL, Campbell EJ, Barker AF, Brantly ML, Eden E, McElvaney NG, Rennard SI, Sandhaus RA, Stocks JM, Stoller JK, Strange C, Turino G, Silverman EK. IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency. Am J Respir Cell Mol Biol. 2008 Jan; 38(1):114-20. PMID: 17690329.
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    106. Strange C, Herth FJ, Kovitz KL, McLennan G, Ernst A, Goldin J, Noppen M, Criner GJ, Sciurba FC. Design of the Endobronchial Valve for Emphysema Palliation Trial (VENT): a non-surgical method of lung volume reduction. BMC Pulm Med. 2007 Jul 03; 7:10. PMID: 17711594.
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    107. Khanna D, Yan X, Tashkin DP, Furst DE, Elashoff R, Roth MD, Silver R, Strange C, Bolster M, Seibold JR, Riley DJ, Hsu VM, Varga J, Schraufnagel DE, Theodore A, Simms R, Wise R, Wigley F, White B, Steen V, Read C, Mayes M, Parsley E, Mubarak K, Connolly MK, Golden J, Olman M, Fessler B, Rothfield N, Metersky M, Clements PJ. Impact of oral cyclophosphamide on health-related quality of life in patients with active scleroderma lung disease: results from the scleroderma lung study. Arthritis Rheum. 2007 May; 56(5):1676-84. PMID: 17469162.
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    108. Demeo DL, Sandhaus RA, Barker AF, Brantly ML, Eden E, McElvaney NG, Rennard S, Burchard E, Stocks JM, Stoller JK, Strange C, Turino GM, Campbell EJ, Silverman EK. Determinants of airflow obstruction in severe alpha-1-antitrypsin deficiency. Thorax. 2007 Sep; 62(9):806-13. PMID: 17389752.
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    109. Carpenter MJ, Strange C, Jones Y, Dickson MR, Carter C, Moseley MA, Gilbert GE. Does genetic testing result in behavioral health change? Changes in smoking behavior following testing for alpha-1 antitrypsin deficiency. Ann Behav Med. 2007 Feb; 33(1):22-8. PMID: 17291167.
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    110. Strange C. Infection in the intensive care unit: a clinician's view of the role of imaging. Semin Roentgenol. 2007 Jan; 42(1):7-10. PMID: 17174170.
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    111. Clayton SB, Mazur JE, Condren S, Hermayer KL, Strange C. Evaluation of an intensive insulin protocol for septic patients in a medical intensive care unit. Crit Care Med. 2006 Dec; 34(12):2974-8. PMID: 17075371.
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    112. Tashkin DP, Elashoff R, Clements PJ, Goldin J, Roth MD, Furst DE, Arriola E, Silver R, Strange C, Bolster M, Seibold JR, Riley DJ, Hsu VM, Varga J, Schraufnagel DE, Theodore A, Simms R, Wise R, Wigley F, White B, Steen V, Read C, Mayes M, Parsley E, Mubarak K, Connolly MK, Golden J, Olman M, Fessler B, Rothfield N, Metersky M. Cyclophosphamide versus placebo in scleroderma lung disease. N Engl J Med. 2006 Jun 22; 354(25):2655-66. PMID: 16790698.
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    113. Strange C, Moseley MA, Jones Y, Schwarz L, Xie L, Brantly ML. Genetic testing of minors for alpha1-antitrypsin deficiency. Arch Pediatr Adolesc Med. 2006 May; 160(5):531-4. PMID: 16651497.
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    114. Stocks JM, Brantly M, Pollock D, Barker A, Kueppers F, Strange C, Donohue JF, Sandhaus R. Multi-center study: the biochemical efficacy, safety and tolerability of a new alpha1-proteinase inhibitor, Zemaira. COPD. 2006 Mar; 3(1):17-23. PMID: 17175661.
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    115. Eden E, Strange C, Holladay B, Xie L. Asthma and allergy in alpha-1 antitrypsin deficiency. Respir Med. 2006 Aug; 100(8):1384-91. PMID: 16403617.
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    116. Stoller JK, Sandhaus RA, Turino G, Dickson R, Rodgers K, Strange C. Delay in diagnosis of alpha1-antitrypsin deficiency: a continuing problem. Chest. 2005 Oct; 128(4):1989-94. PMID: 16236846.
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    117. Strange C, Highland KB. Pulmonary hypertension in interstitial lung disease. Curr Opin Pulm Med. 2005 Sep; 11(5):452-5. PMID: 16093821.
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    118. Strange C, Stoller JK, Sandhaus RA, Dickson R, Turino G. Results of a survey of patients with alpha-1 antitrypsin deficiency. Respiration. 2006; 73(2):185-90. PMID: 16141711.
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    119. Flume PA, Strange C, Ye X, Ebeling M, Hulsey T, Clark LL. Pneumothorax in cystic fibrosis. Chest. 2005 Aug; 128(2):720-8. PMID: 16100160.
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    120. Bowlus CL, Willner I, Zern MA, Reuben A, Chen P, Holladay B, Xie L, Woolson RF, Strange C. Factors associated with advanced liver disease in adults with alpha1-antitrypsin deficiency. Clin Gastroenterol Hepatol. 2005 Apr; 3(4):390-6. PMID: 15822045.
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    121. Stoller JK, Tomashefski J, Crystal RG, Arroliga A, Strange C, Killian DN, Schluchter MD, Wiedemann HP. Mortality in individuals with severe deficiency of alpha1-antitrypsin: findings from the National Heart, Lung, and Blood Institute Registry. Chest. 2005 Apr; 127(4):1196-204. PMID: 15821195.
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    122. Fanos JH, Strange C. "The lion, the witch and the wardrobe": impact on sibs of individuals with AAT deficiency. Am J Med Genet A. 2004 Oct 15; 130A(3):251-7. PMID: 15378547.
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    123. Strange C, Highland KB. Interstitial lung disease in the patient who has connective tissue disease. Clin Chest Med. 2004 Sep; 25(3):549-59, vii. PMID: 15331191.
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    124. Strange C, Dickson R, Carter C, Carpenter MJ, Holladay B, Lundquist R, Brantly ML. Genetic testing for alpha1-antitrypsin deficiency. Genet Med. 2004 Jul-Aug; 6(4):204-10. PMID: 15266208.
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    125. Highland KB, Strange C, Mazur J, Simpson KN. Treatment of pulmonary arterial hypertension: a preliminary decision analysis. Chest. 2003 Dec; 124(6):2087-92. PMID: 14665484.
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    126. Highland KB, Strange C, Heffner JE. Long-term effects of inhaled corticosteroids on FEV1 in patients with chronic obstructive pulmonary disease. A meta-analysis. Ann Intern Med. 2003 Jun 17; 138(12):969-73. PMID: 12809453.
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    127. Loveland SM, Lewin JJ, Amabile CM, Strange C, Mazur JE. Obese man treated with drotrecogin alfa (activated). Ann Pharmacother. 2003 Jun; 37(6):918-9. PMID: 12773088.
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    128. Doelken P, Strange C. Chest ultrasound for "Dummies". Chest. 2003 Feb; 123(2):332-3. PMID: 12576345.
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    129. Strange C. Alpha-1 Foundation research registry: from the past to the future. J Pediatr Gastroenterol Nutr. 2002 Jan; 34(1):1. PMID: 11791523.
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    130. Strange C, Bolster M, Mazur J, Taylor M, Gossage JR, Silver R. Hemodynamic effects of epoprostenol in patients with systemic sclerosis and pulmonary hypertension. Chest. 2000 Oct; 118(4):1077-82. PMID: 11035680.
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    131. Strange C. Pleural complications in the intensive care unit. Clin Chest Med. 1999 Jun; 20(2):317-27. PMID: 10386259.
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