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Bryan P Toole

Title
InstitutionMedical University of South Carolina
DepartmentRegenerative Medicine and Cell Biology
AddressP.O. Box MSC 508
BSB 612
173 Ashley Ave.
Phone843-792-7004
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Dai L, Chen Y, Bonstaff K, Doyle L, Toole B, Parsons C, Qin Z. Induction of hyaluronan production by oncogenic KSHV and the contribution to viral pathogenesis in AIDS patients. Cancer Lett. 2015 Jul 01; 362(2):158-66. PMID: 25837851.
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    2. Zhang C, Cao S, Toole BP, Xu Y. Cancer may be a pathway to cell survival under persistent hypoxia and elevated ROS: a model for solid-cancer initiation and early development. Int J Cancer. 2015 May 01; 136(9):2001-11. PMID: 24828886.
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    3. Purushothaman A, Toole BP. Serglycin proteoglycan is required for multiple myeloma cell adhesion, in vivo growth, and vascularization. J Biol Chem. 2014 Feb 28; 289(9):5499-509. PMID: 24403068.
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    4. Grass GD, Dai L, Qin Z, Parsons C, Toole BP. CD147: regulator of hyaluronan signaling in invasiveness and chemoresistance. Adv Cancer Res. 2014; 123:351-73. PMID: 25081536.
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    5. Inai K, Burnside JL, Hoffman S, Toole BP, Sugi Y. BMP-2 induces versican and hyaluronan that contribute to post-EMT AV cushion cell migration. PLoS One. 2013; 8(10):e77593. PMID: 24147033.
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    6. Grass GD, Tolliver LB, Bratoeva M, Toole BP. CD147, CD44, and the epidermal growth factor receptor (EGFR) signaling pathway cooperate to regulate breast epithelial cell invasiveness. J Biol Chem. 2013 Sep 06; 288(36):26089-104. PMID: 23888049.
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    7. Spaeth EL, Labaff AM, Toole BP, Klopp A, Andreeff M, Marini FC. Mesenchymal CD44 expression contributes to the acquisition of an activated fibroblast phenotype via TWIST activation in the tumor microenvironment. Cancer Res. 2013 Sep 01; 73(17):5347-59. PMID: 23838935.
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    8. Dai L, Bai L, Lu Y, Xu Z, Reiss K, Del Valle L, Kaleeba J, Toole BP, Parsons C, Qin Z. Emmprin and KSHV: new partners in viral cancer pathogenesis. Cancer Lett. 2013 Sep 01; 337(2):161-6. PMID: 23743354.
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    9. Dai L, Guinea MC, Slomiany MG, Bratoeva M, Grass GD, Tolliver LB, Maria BL, Toole BP. CD147-dependent heterogeneity in malignant and chemoresistant properties of cancer cells. Am J Pathol. 2013 Feb; 182(2):577-85. PMID: 23178078.
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    10. Qin Z, Dai L, Defee M, Findlay VJ, Watson DK, Toole BP, Cameron J, Peruzzi F, Kirkwood K, Parsons C. Kaposi's sarcoma-associated herpesvirus suppression of DUSP1 facilitates cellular pathogenesis following de novo infection. J Virol. 2013 Jan; 87(1):621-35. PMID: 23097457.
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    11. Grass GD, Bratoeva M, Toole BP. Regulation of invadopodia formation and activity by CD147. J Cell Sci. 2012 Feb 01; 125(Pt 3):777-88. PMID: 22389410.
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    12. Dai L, Qin Z, Defee M, Toole BP, Kirkwood KL, Parsons C. Kaposi sarcoma-associated herpesvirus (KSHV) induces a functional tumor-associated phenotype for oral fibroblasts. Cancer Lett. 2012 May 28; 318(2):214-20. PMID: 22186301.
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    13. Dai L, Bratoeva M, Toole BP, Qin Z, Parsons C. KSHV activation of VEGF secretion and invasion for endothelial cells is mediated through viral upregulation of emmprin-induced signal transduction. Int J Cancer. 2012 Aug 15; 131(4):834-43. PMID: 21918972.
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    14. Harten IA, Zahr RS, Lemire JM, Machan JT, Moses MA, Doiron RJ, Curatolo AS, Rothman FG, Wight TN, Toole BP, Gordon LB. Age-dependent loss of MMP-3 in Hutchinson-Gilford progeria syndrome. J Gerontol A Biol Sci Med Sci. 2011 Nov; 66(11):1201-7. PMID: 21852285.
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    15. Kawakami T, Sameshima T, Hojo H, Koga K, Nakahara Y, Toole BP, Suzumiya J, Okada Y, Iwasaki A, Nabeshima K. Synthetic emmprin peptides with chitobiose substitution stimulate MMP-2 production by fibroblasts. BMC Cancer. 2011 Jul 17; 11:300. PMID: 21762534.
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    16. Qin Z, Dai L, Bratoeva M, Slomiany MG, Toole BP, Parsons C. Cooperative roles for emmprin and LYVE-1 in the regulation of chemoresistance for primary effusion lymphoma. Leukemia. 2011 Oct; 25(10):1598-609. PMID: 21660043.
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    17. Koga K, Aoki M, Sameshima T, Hamasaki M, Egawa N, Seiki M, Toole BP, Suzumiya J, Nabeshima K. Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion. Int J Oncol. 2011 Sep; 39(3):657-64. PMID: 21637915.
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    18. Defee MR, Qin Z, Dai L, Toole BP, Isaacs JS, Parsons CH. Extracellular Hsp90 serves as a co-factor for NF-?B activation and cellular pathogenesis induced by an oncogenic herpesvirus. Am J Cancer Res. 2011; 1(5):687-700. PMID: 21994906.
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    19. Qin Z, Dai L, Toole B, Robertson E, Parsons C. Regulation of Nm23-H1 and cell invasiveness by Kaposi's sarcoma-associated herpesvirus. J Virol. 2011 Apr; 85(7):3596-606. PMID: 21270158.
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    20. Qin Z, Dai L, Slomiany MG, Toole BP, Parsons C. Direct activation of emmprin and associated pathogenesis by an oncogenic herpesvirus. Cancer Res. 2010 May 15; 70(10):3884-9. PMID: 20406987.
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    21. Matsumoto K, Li Y, Jakuba C, Sugiyama Y, Sayo T, Okuno M, Dealy CN, Toole BP, Takeda J, Yamaguchi Y, Kosher RA. Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb. Development. 2009 Aug; 136(16):2825-35. PMID: 19633173.
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    22. Slomiany MG, Dai L, Bomar PA, Knackstedt TJ, Kranc DA, Tolliver L, Maria BL, Toole BP. Abrogating drug resistance in malignant peripheral nerve sheath tumors by disrupting hyaluronan-CD44 interactions with small hyaluronan oligosaccharides. Cancer Res. 2009 Jun 15; 69(12):4992-8. PMID: 19470767.
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    23. Slomiany MG, Grass GD, Robertson AD, Yang XY, Maria BL, Beeson C, Toole BP. Hyaluronan, CD44, and emmprin regulate lactate efflux and membrane localization of monocarboxylate transporters in human breast carcinoma cells. Cancer Res. 2009 Feb 15; 69(4):1293-301. PMID: 19176383.
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    24. Maria BL, Gupta N, Gilg AG, Abdel-Wahab M, Leonard AP, Slomiany M, Wheeler WG, Tolliver LB, Babcock MA, Lucas JT, Toole BP. Targeting hyaluronan interactions in spinal cord astrocytomas and diffuse pontine gliomas. J Child Neurol. 2008 Oct; 23(10):1214-20. PMID: 18952588.
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    25. Toole BP, Ghatak S, Misra S. Hyaluronan oligosaccharides as a potential anticancer therapeutic. Curr Pharm Biotechnol. 2008 Aug; 9(4):249-52. PMID: 18691085.
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    26. Toole BP, Slomiany MG. Hyaluronan, CD44 and Emmprin: partners in cancer cell chemoresistance. Drug Resist Updat. 2008 Jun; 11(3):110-21. PMID: 18490190.
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    27. Toole BP, Slomiany MG. Hyaluronan: a constitutive regulator of chemoresistance and malignancy in cancer cells. Semin Cancer Biol. 2008 Aug; 18(4):244-50. PMID: 18534864.
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    28. Gilg AG, Tye SL, Tolliver LB, Wheeler WG, Visconti RP, Duncan JD, Kostova FV, Bolds LN, Toole BP, Maria BL. Targeting hyaluronan interactions in malignant gliomas and their drug-resistant multipotent progenitors. Clin Cancer Res. 2008 Mar 15; 14(6):1804-13. PMID: 18347183.
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    29. Misra S, Obeid LM, Hannun YA, Minamisawa S, Berger FG, Markwald RR, Toole BP, Ghatak S. Hyaluronan constitutively regulates activation of COX-2-mediated cell survival activity in intestinal epithelial and colon carcinoma cells. J Biol Chem. 2008 May 23; 283(21):14335-44. PMID: 18326857.
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    30. Wirrig EE, Snarr BS, Chintalapudi MR, O'neal JL, Phelps AL, Barth JL, Fresco VM, Kern CB, Mjaatvedt CH, Toole BP, Hoffman S, Trusk TC, Argraves WS, Wessels A. Cartilage link protein 1 (Crtl1), an extracellular matrix component playing an important role in heart development. Dev Biol. 2007 Oct 15; 310(2):291-303. PMID: 17822691.
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    31. Li Y, Toole BP, Dealy CN, Kosher RA. Hyaluronan in limb morphogenesis. Dev Biol. 2007 May 15; 305(2):411-20. PMID: 17362908.
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    32. Koga K, Nabeshima K, Aoki M, Kawakami T, Hamasaki M, Toole BP, Nakayama J, Iwasaki H. Emmprin in epithelioid sarcoma: expression in tumor cell membrane and stimulation of MMP-2 production in tumor-associated fibroblasts. Int J Cancer. 2007 Feb 15; 120(4):761-8. PMID: 17131322.
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    33. Yokoyama U, Minamisawa S, Quan H, Ghatak S, Akaike T, Segi-Nishida E, Iwasaki S, Iwamoto M, Misra S, Tamura K, Hori H, Yokota S, Toole BP, Sugimoto Y, Ishikawa Y. Chronic activation of the prostaglandin receptor EP4 promotes hyaluronan-mediated neointimal formation in the ductus arteriosus. J Clin Invest. 2006 Nov; 116(11):3026-34. PMID: 17080198.
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    34. Misra S, Toole BP, Ghatak S. Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cells. J Biol Chem. 2006 Nov 17; 281(46):34936-41. PMID: 16959784.
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    35. Kern CB, Twal WO, Mjaatvedt CH, Fairey SE, Toole BP, Iruela-Arispe ML, Argraves WS. Proteolytic cleavage of versican during cardiac cushion morphogenesis. Dev Dyn. 2006 Aug; 235(8):2238-47. PMID: 16691565.
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    36. Haginoya E, Hojo H, Nakahara Y, Nakahara Y, Nabeshima K, Toole BP, Watanabe Y. Synthesis of a glycosylated peptide thioester by the Boc strategy and its application to segment condensation. Biosci Biotechnol Biochem. 2006 Jun; 70(6):1338-49. PMID: 16794312.
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    37. Lemire JM, Patis C, Gordon LB, Sandy JD, Toole BP, Weiss AS. Aggrecan expression is substantially and abnormally upregulated in Hutchinson-Gilford Progeria Syndrome dermal fibroblasts. Mech Ageing Dev. 2006 Aug; 127(8):660-9. PMID: 16650460.
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    38. Braundmeier AG, Fazleabas AT, Lessey BA, Guo H, Toole BP, Nowak RA. Extracellular matrix metalloproteinase inducer regulates metalloproteinases in human uterine endometrium. J Clin Endocrinol Metab. 2006 Jun; 91(6):2358-65. PMID: 16522689.
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    39. Schmidt R, Bültmann A, Ungerer M, Joghetaei N, Bülbül O, Thieme S, Chavakis T, Toole BP, Gawaz M, Schömig A, May AE. Extracellular matrix metalloproteinase inducer regulates matrix metalloproteinase activity in cardiovascular cells: implications in acute myocardial infarction. Circulation. 2006 Feb 14; 113(6):834-41. PMID: 16461815.
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    40. Boregowda RK, Appaiah HN, Siddaiah M, Kumarswamy SB, Sunila S, Thimmaiah KN, Mortha K, Toole B, Banerjee Sd. Expression of hyaluronan in human tumor progression. J Carcinog. 2006 Jan 10; 5:2. PMID: 16401353.
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    41. Misra S, Ghatak S, Toole BP. Regulation of MDR1 expression and drug resistance by a positive feedback loop involving hyaluronan, phosphoinositide 3-kinase, and ErbB2. J Biol Chem. 2005 May 27; 280(21):20310-5. PMID: 15784621.
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    42. Yan L, Zucker S, Toole BP. Roles of the multifunctional glycoprotein, emmprin (basigin; CD147), in tumour progression. Thromb Haemost. 2005 Feb; 93(2):199-204. PMID: 15711733.
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    43. Ghatak S, Misra S, Toole BP. Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells. J Biol Chem. 2005 Mar 11; 280(10):8875-83. PMID: 15632176.
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    44. Toole BP, Zoltan-Jones A, Misra S, Ghatak S. Hyaluronan: a critical component of epithelial-mesenchymal and epithelial-carcinoma transitions. Cells Tissues Organs. 2005; 179(1-2):66-72. PMID: 15942194.
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    45. Toole BP. Hyaluronan: from extracellular glue to pericellular cue. Nat Rev Cancer. 2004 Jul; 4(7):528-39. PMID: 15229478.
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    46. Nabeshima K, Suzumiya J, Nagano M, Ohshima K, Toole BP, Tamura K, Iwasaki H, Kikuchi M. Emmprin, a cell surface inducer of matrix metalloproteinases (MMPs), is expressed in T-cell lymphomas. J Pathol. 2004 Mar; 202(3):341-51. PMID: 14991900.
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    47. Marieb EA, Zoltan-Jones A, Li R, Misra S, Ghatak S, Cao J, Zucker S, Toole BP. Emmprin promotes anchorage-independent growth in human mammary carcinoma cells by stimulating hyaluronan production. Cancer Res. 2004 Feb 15; 64(4):1229-32. PMID: 14983875.
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    48. Zoltan-Jones A, Huang L, Ghatak S, Toole BP. Elevated hyaluronan production induces mesenchymal and transformed properties in epithelial cells. J Biol Chem. 2003 Nov 14; 278(46):45801-10. PMID: 12954618.
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    49. Misra S, Ghatak S, Zoltan-Jones A, Toole BP. Regulation of multidrug resistance in cancer cells by hyaluronan. J Biol Chem. 2003 Jul 11; 278(28):25285-8. PMID: 12738783.
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    50. Gordon LB, Harten IA, Calabro A, Sugumaran G, Csoka AB, Brown WT, Hascall V, Toole BP. Hyaluronan is not elevated in urine or serum in Hutchinson-Gilford Progeria Syndrome. Hum Genet. 2003 Jul; 113(2):178-87. PMID: 12728312.
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    51. Ward JA, Huang L, Guo H, Ghatak S, Toole BP. Perturbation of hyaluronan interactions inhibits malignant properties of glioma cells. Am J Pathol. 2003 May; 162(5):1403-9. PMID: 12707023.
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    52. Sameshima T, Nabeshima K, Toole BP, Inoue T, Yokogami K, Nakano S, Ohi T, Wakisaka S. Correlation of emmprin expression in vascular endothelial cells with blood-brain-barrier function: a study using magnetic resonance imaging enhanced by Gd-DTPA and immunohistochemistry in brain tumors. Virchows Arch. 2003 Jun; 442(6):577-84. PMID: 12719975.
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    53. Toole BP. Emmprin (CD147), a cell surface regulator of matrix metalloproteinase production and function. Curr Top Dev Biol. 2003; 54:371-89. PMID: 12696756.
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    54. Toole BP, Hascall VC. Hyaluronan and tumor growth. Am J Pathol. 2002 Sep; 161(3):745-7. PMID: 12213700.
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    55. Ghatak S, Misra S, Toole BP. Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway. J Biol Chem. 2002 Oct 11; 277(41):38013-20. PMID: 12145277.
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    56. Yurchenko V, Zybarth G, O'Connor M, Dai WW, Franchin G, Hao T, Guo H, Hung HC, Toole B, Gallay P, Sherry B, Bukrinsky M. Active site residues of cyclophilin A are crucial for its signaling activity via CD147. J Biol Chem. 2002 Jun 21; 277(25):22959-65. PMID: 11943775.
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    57. Toole BP. Hyaluronan promotes the malignant phenotype. Glycobiology. 2002 Mar; 12(3):37R-42R. PMID: 11971857.
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    58. Caudroy S, Polette M, Nawrocki-Raby B, Cao J, Toole BP, Zucker S, Birembaut P. EMMPRIN-mediated MMP regulation in tumor and endothelial cells. Clin Exp Metastasis. 2002; 19(8):697-702. PMID: 12553375.
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    59. Toole BP, Wight TN, Tammi MI. Hyaluronan-cell interactions in cancer and vascular disease. J Biol Chem. 2002 Feb 15; 277(7):4593-6. PMID: 11717318.
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    60. Yurchenko V, O'Connor M, Dai WW, Guo H, Toole B, Sherry B, Bukrinsky M. CD147 is a signaling receptor for cyclophilin B. Biochem Biophys Res Commun. 2001 Nov 09; 288(4):786-8. PMID: 11688976.
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    61. Zucker S, Hymowitz M, Rollo EE, Mann R, Conner CE, Cao J, Foda HD, Tompkins DC, Toole BP. Tumorigenic potential of extracellular matrix metalloproteinase inducer. Am J Pathol. 2001 Jun; 158(6):1921-8. PMID: 11395366.
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    62. Pushkarsky T, Zybarth G, Dubrovsky L, Yurchenko V, Tang H, Guo H, Toole B, Sherry B, Bukrinsky M. CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A. Proc Natl Acad Sci U S A. 2001 May 22; 98(11):6360-5. PMID: 11353871.
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    63. Toole BP. Hyaluronan in morphogenesis. Semin Cell Dev Biol. 2001 Apr; 12(2):79-87. PMID: 11292373.
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    64. Li R, Huang L, Guo H, Toole BP. Basigin (murine EMMPRIN) stimulates matrix metalloproteinase production by fibroblasts. J Cell Physiol. 2001 Mar; 186(3):371-9. PMID: 11169976.
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    65. Toole BP, Yu Q, Underhill CB. Hyaluronan and hyaluronan-binding proteins. Probes for specific detection. Methods Mol Biol. 2001; 171:479-85. PMID: 11450261.
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    66. Sameshima T, Nabeshima K, Toole BP, Yokogami K, Okada Y, Goya T, Koono M, Wakisaka S. Expression of emmprin (CD147), a cell surface inducer of matrix metalloproteinases, in normal human brain and gliomas. Int J Cancer. 2000 Oct 01; 88(1):21-7. PMID: 10962435.
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    67. Huang L, Grammatikakis N, Yoneda M, Banerjee SD, Toole BP. Molecular characterization of a novel intracellular hyaluronan-binding protein. J Biol Chem. 2000 Sep 22; 275(38):29829-39. PMID: 10887182.
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    68. Sameshima T, Nabeshima K, Toole BP, Yokogami K, Okada Y, Goya T, Koono M, Wakisaka S. Glioma cell extracellular matrix metalloproteinase inducer (EMMPRIN) (CD147) stimulates production of membrane-type matrix metalloproteinases and activated gelatinase A in co-cultures with brain-derived fibroblasts. Cancer Lett. 2000 Sep 01; 157(2):177-84. PMID: 10936678.
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    69. Toole BP. Hyaluronan is not just a goo! J Clin Invest. 2000 Aug; 106(3):335-6. PMID: 10930435.
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    70. Peterson RM, Yu Q, Stamenkovic I, Toole BP. Perturbation of hyaluronan interactions by soluble CD44 inhibits growth of murine mammary carcinoma cells in ascites. Am J Pathol. 2000 Jun; 156(6):2159-67. PMID: 10854236.
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    71. Guo H, Li R, Zucker S, Toole BP. EMMPRIN (CD147), an inducer of matrix metalloproteinase synthesis, also binds interstitial collagenase to the tumor cell surface. Cancer Res. 2000 Feb 15; 60(4):888-91. PMID: 10706100.
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    72. Bordador LC, Li X, Toole B, Chen B, Regezi J, Zardi L, Hu Y, Ramos DM. Expression of emmprin by oral squamous cell carcinoma. Int J Cancer. 2000 Feb 01; 85(3):347-52. PMID: 10652425.
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    73. Caudroy S, Polette M, Tournier JM, Burlet H, Toole B, Zucker S, Birembaut P. Expression of the extracellular matrix metalloproteinase inducer (EMMPRIN) and the matrix metalloproteinase-2 in bronchopulmonary and breast lesions. J Histochem Cytochem. 1999 Dec; 47(12):1575-80. PMID: 10567441.
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    74. Lim M, Martinez T, Jablons D, Cameron R, Guo H, Toole B, Li JD, Basbaum C. Tumor-derived EMMPRIN (extracellular matrix metalloproteinase inducer) stimulates collagenase transcription through MAPK p38. FEBS Lett. 1998 Dec 11; 441(1):88-92. PMID: 9877171.
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    75. Guo H, Majmudar G, Jensen TC, Biswas C, Toole BP, Gordon MK. Characterization of the gene for human EMMPRIN, a tumor cell surface inducer of matrix metalloproteinases. Gene. 1998 Oct 05; 220(1-2):99-108. PMID: 9767135.
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    76. Zeng C, Toole BP, Kinney SD, Kuo JW, Stamenkovic I. Inhibition of tumor growth in vivo by hyaluronan oligomers. Int J Cancer. 1998 Jul 29; 77(3):396-401. PMID: 9663602.
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    77. Huang L, Grammatikakis N, Toole BP. Organization of the chick CDC37 gene. J Biol Chem. 1998 Feb 06; 273(6):3598-603. PMID: 9452487.
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    78. Yu Q, Toole BP, Stamenkovic I. Induction of apoptosis of metastatic mammary carcinoma cells in vivo by disruption of tumor cell surface CD44 function. J Exp Med. 1997 Dec 15; 186(12):1985-96. PMID: 9396767.
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    79. Toole BP. Hyaluronan in morphogenesis. J Intern Med. 1997 Jul; 242(1):35-40. PMID: 9260564.
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    80. Polette M, Gilles C, Marchand V, Lorenzato M, Toole B, Tournier JM, Zucker S, Birembaut P. Tumor collagenase stimulatory factor (TCSF) expression and localization in human lung and breast cancers. J Histochem Cytochem. 1997 May; 45(5):703-9. PMID: 9154157.
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    81. Guo H, Zucker S, Gordon MK, Toole BP, Biswas C. Stimulation of matrix metalloproteinase production by recombinant extracellular matrix metalloproteinase inducer from transfected Chinese hamster ovary cells. J Biol Chem. 1997 Jan 03; 272(1):24-7. PMID: 8995219.
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    82. Yu Q, Toole BP. Common pattern of CD44 isoforms is expressed in morphogenetically active epithelia. Dev Dyn. 1997 Jan; 208(1):1-10. PMID: 8989516.
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    83. Yu Q, Grammatikakis N, Toole BP. Expression of multiple CD44 isoforms in the apical ectodermal ridge of the embryonic mouse limb. Dev Dyn. 1996 Oct; 207(2):204-14. PMID: 8906423.
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    84. Yu Q, Toole BP. A new alternatively spliced exon between v9 and v10 provides a molecular basis for synthesis of soluble CD44. J Biol Chem. 1996 Aug 23; 271(34):20603-7. PMID: 8702806.
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    85. Yeo TK, Nagy JA, Yeo KT, Dvorak HF, Toole BP. Increased hyaluronan at sites of attachment to mesentery by CD44-positive mouse ovarian and breast tumor cells. Am J Pathol. 1996 Jun; 148(6):1733-40. PMID: 8669459.
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    86. DeCastro R, Zhang Y, Guo H, Kataoka H, Gordon MK, Toole Bp, Biswas G. Human keratinocytes express EMMPRIN, an extracellular matrix metalloproteinase inducer. J Invest Dermatol. 1996 Jun; 106(6):1260-5. PMID: 8752667.
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    87. Knudson CB, Munaim SI, Toole BP. Ectodermal stimulation of the production of hyaluronan-dependent pericellular matrix by embryonic limb mesodermal cells. Dev Dyn. 1995 Oct; 204(2):186-91. PMID: 8589442.
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    88. Deyst KA, Toole BP. Production of hyaluronan-dependent pericellular matrix by embryonic rat glial cells. Brain Res Dev Brain Res. 1995 Aug 28; 88(1):122-5. PMID: 7493403.
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    89. Grammatikakis N, Grammatikakis A, Yoneda M, Yu Q, Banerjee SD, Toole BP. A novel glycosaminoglycan-binding protein is the vertebrate homologue of the cell cycle control protein, Cdc37. J Biol Chem. 1995 Jul 07; 270(27):16198-205. PMID: 7608185.
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    90. Grammatikakis N, Toole BP. Functional domain mapping using M13 deletions. Biochem Mol Biol Int. 1995 Jul; 36(4):771-9. PMID: 8528139.
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    91. Yu Q, Toole BP. Biotinylated hyaluronan as a probe for detection of binding proteins in cells and tissues. Biotechniques. 1995 Jul; 19(1):122-4, 126-9. PMID: 7545407.
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    92. Toole BP, Turner RE, Banerjee SD. Hyaluronan-binding protein in chondrogenesis and angiogenesis in the developing limb. Prog Clin Biol Res. 1993; 383B:437-44. PMID: 7509488.
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    93. Banerjee SD, Toole BP. Hyaluronan-binding protein in endothelial cell morphogenesis. J Cell Biol. 1992 Nov; 119(3):643-52. PMID: 1383238.
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    94. Yu Q, Banerjee SD, Toole BP. The role of hyaluronan-binding protein in assembly of pericellular matrices. Dev Dyn. 1992 Feb; 193(2):145-51. PMID: 1374658.
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    95. Banerjee SD, Toole BP. Monoclonal antibody to chick embryo hyaluronan-binding protein: changes in distribution of binding protein during early brain development. Dev Biol. 1991 Jul; 146(1):186-97. PMID: 1711984.
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    96. Munaim SI, Klagsbrun M, Toole BP. Hyaluronan-dependent pericellular coats of chick embryo limb mesodermal cells: induction by basic fibroblast growth factor. Dev Biol. 1991 Feb; 143(2):297-302. PMID: 1899405.
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    97. Toole BP. Hyaluronan and its binding proteins, the hyaladherins. Curr Opin Cell Biol. 1990 Oct; 2(5):839-44. PMID: 1707285.
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    98. Marks MS, Chi-Rosso G, Toole BP. Hyaluronate-binding proteins of murine brain. J Neurochem. 1990 Jan; 54(1):171-80. PMID: 1688375.
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    99. McCarthy MT, Toole BP. Membrane-associated hyaluronate-binding activity of chondrosarcoma chondrocytes. J Cell Physiol. 1989 Oct; 141(1):191-202. PMID: 2476451.
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    100. Toole BP, Munaim SI, Welles S, Knudson CB. Hyaluronate-cell interactions and growth factor regulation of hyaluronate synthesis during limb development. Ciba Found Symp. 1989; 143:138-45; discussion 145-9 281-5. PMID: 2680342.
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    101. Knudson W, Biswas C, Li XQ, Nemec RE, Toole BP. The role and regulation of tumour-associated hyaluronan. Ciba Found Symp. 1989; 143:150-9; discussion 159-69, 281-5. PMID: 2680343.
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    102. Munaim SI, Klagsbrun M, Toole BP. Developmental changes in fibroblast growth factor in the chicken embryo limb bud. Proc Natl Acad Sci U S A. 1988 Nov; 85(21):8091-3. PMID: 3186711.
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    103. Knudson W, Toole BP. Membrane association of the hyaluronate stimulatory factor from LX-1 human lung carcinoma cells. J Cell Biochem. 1988 Nov; 38(3):165-77. PMID: 3147984.
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    104. Knudson CB, Toole BP. Epithelial-mesenchymal interaction in the regulation of hyaluronate production during limb development. Biochem Int. 1988 Oct; 17(4):735-45. PMID: 3240321.
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    105. Nemec RE, Toole BP, Knudson W. The cell surface hyaluronate binding sites of invasive human bladder carcinoma cells. Biochem Biophys Res Commun. 1987 Nov 30; 149(1):249-57. PMID: 2446619.
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    106. Knudson CB, Toole BP. Hyaluronate-cell interactions during differentiation of chick embryo limb mesoderm. Dev Biol. 1987 Nov; 124(1):82-90. PMID: 2444482.
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    107. Goldberg RL, Toole BP. Hyaluronate inhibition of cell proliferation. Arthritis Rheum. 1987 Jul; 30(7):769-78. PMID: 3619961.
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    108. Chi-Rosso G, Toole BP. Hyaluronate-binding protein of simian virus 40-transformed 3T3 cells: membrane distribution and reconstitution into lipid vesicles. J Cell Biochem. 1987 Mar; 33(3):173-83. PMID: 2437135.
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    109. Knudson CB, Toole BP. Changes in the pericellular matrix during differentiation of limb bud mesoderm. Dev Biol. 1985 Dec; 112(2):308-18. PMID: 3935502.
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    110. Knudson CB, Toole BP. Fluorescent morphological probe for hyaluronate. J Cell Biol. 1985 May; 100(5):1753-8. PMID: 2580846.
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    111. Orkin RW, Knudson W, Toole BP. Loss of hyaluronate-dependent coat during myoblast fusion. Dev Biol. 1985 Feb; 107(2):527-30. PMID: 3972168.
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    112. Goldberg RL, Toole BP. Pericellular coat of chick embryo chondrocytes: structural role of hyaluronate. J Cell Biol. 1984 Dec; 99(6):2114-22. PMID: 6501414.
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    113. Knudson W, Biswas C, Toole BP. Interactions between human tumor cells and fibroblasts stimulate hyaluronate synthesis. Proc Natl Acad Sci U S A. 1984 Nov; 81(21):6767-71. PMID: 6593727.
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    114. Goldberg RL, Seidman JD, Chi-Rosso G, Toole BP. Endogenous hyaluronate-cell surface interactions in 3T3 and simian virus-transformed 3T3 cells. J Biol Chem. 1984 Aug 10; 259(15):9440-6. PMID: 6086634.
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    115. Goldberg RL, Toole BP. Hyaluronate coat formation and cell spreading in rat fibrosarcoma cells. Exp Cell Res. 1984 Mar; 151(1):258-63. PMID: 6698121.
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    116. Knudson W, Biswas C, Toole BP. Stimulation of glycosaminoglycan production in murine tumors. J Cell Biochem. 1984; 25(4):183-96. PMID: 6511822.
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    117. Underhill CB, Chi-Rosso G, Toole BP. Effects of detergent solubilization on the hyaluronate-binding protein from membranes of simian virus 40-transformed 3T3 cells. J Biol Chem. 1983 Jul 10; 258(13):8086-91. PMID: 6190806.
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    118. Goldberg RL, Toole BP. Monensin inhibition of hyaluronate synthesis in rat fibrosarcoma cells. J Biol Chem. 1983 Jun 10; 258(11):7041-6. PMID: 6853512.
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    119. Belsky E, Toole BP. Hyaluronate and hyaluronidase in the developing chick embryo kidney. Cell Differ. 1983 Feb; 12(2):61-6. PMID: 6402309.
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    120. Goldberg RL, Underhill CB, Toole BP. Affinity chromatography of hyaluronate on glutaraldehyde-fixed SV-3T3 cells. Anal Biochem. 1982 Sep 01; 125(1):59-65. PMID: 6293340.
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    121. Orkin RW, Underhill CB, Toole BP. Hyaluronate degradation in 3T3 and simian virus-transformed 3T3 cells. J Biol Chem. 1982 May 25; 257(10):5821-6. PMID: 6279615.
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    122. Underhill CB, Toole BP. Transformation-dependent loss of the hyaluronate-containing coats of cultured cells. J Cell Physiol. 1982 Feb; 110(2):123-8. PMID: 7040425.
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    123. Toole BP. Transitions in extracellular macromolecules during avian ocular development. Prog Clin Biol Res. 1982; 82:17-34. PMID: 6810370.
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    124. Toole BP. Developmental role of hyaluronate. Connect Tissue Res. 1982; 10(1):93-100. PMID: 6216071.
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    125. Wright TC, Underhill CB, Toole BP, Karnovsky MJ. Divalent cation-independent aggregation of rat-1 fibroblasts infected with a temperature-sensitive mutant of Rous sarcoma virus. Cancer Res. 1981 Dec; 41(12 Pt 1):5107-13. PMID: 6272988.
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    126. Mikuni-Takagaki Y, Toole BP. Hyaluronate-protein complex of rous sarcoma virus-transformed chick embryo fibroblasts. J Biol Chem. 1981 Aug 25; 256(16):8463-9. PMID: 6267045.
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    127. Underhill CB, Toole BP. Receptors for hyaluronate on the surface of parent and virus-transformed cell lines: binding and aggregation studies. Exp Cell Res. 1981 Feb; 131(2):419-23. PMID: 7202543.
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    128. Underhill CB, Toole BP. Physical characteristics of hyaluronate binding to the surface of simian virus 40-transformed 3T3 cells. J Biol Chem. 1980 May 25; 255(10):4544-9. PMID: 6246078.
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    129. Mikuni-Takagaki Y, Toole BP. Cell-substratum attachment and cell surface hyaluronate of Rous sarcoma virus-transformed chondrocytes. J Cell Biol. 1980 May; 85(2):481-8. PMID: 6246121.
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    130. Orkin RW, Toole BP. Chick embryo fibroblasts produce two forms of hyaluronidase. J Cell Biol. 1980 May; 85(2):248-57. PMID: 7372707.
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    131. Orkin RW, Toole BP. Isolation and characterization of hyaluronidase from cultures of chick embryo skin- and muscle-derived fibroblasts. J Biol Chem. 1980 Feb 10; 255(3):1036-42. PMID: 7356648.
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    132. Toole BP, Biswas C, Gross J. Hyaluronate and invasiveness of the rabbit V2 carcinoma. Proc Natl Acad Sci U S A. 1979 Dec; 76(12):6299-303. PMID: 293721.
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    133. Mikuni-Takagaki Y, Toole BP. Shedding of hyaluronate from the cell surface of Rous sarcoma virus-transformed chondrocytes. J Biol Chem. 1979 Sep 10; 254(17):8409-15. PMID: 224053.
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    134. Underhill CB, Toole BP. Binding of hyaluronate to the surface of cultured cells. J Cell Biol. 1979 Aug; 82(2):475-84. PMID: 479311.
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    135. Hull SA, Schuetz A, Toole B. In vitro inhibition of oocyte and follicular maturation and spawning in starfish (Asterias forbesi) by 2-4-dinitrophenol. Differentiation. 1979; 15(2):127-32. PMID: 527774.
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    136. Linsenmayer TF, Gibney E, Toole BP, Gross J. Cellular adhesion to collagen. Exp Cell Res. 1978 Oct 15; 116(2):470-4. PMID: 101384.
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    137. Orkin RW, Toole BP. Hyaluronidase activity and hyaluronate content of the developing chick embryo heart. Dev Biol. 1978 Oct; 66(2):308-20. PMID: 29813.
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    138. Toole BP, Linsenmayer TF. Newer knowledge of skeletogenesis: macromolecular transitions in the extracellular matrix. Clin Orthop Relat Res. 1977 Nov-Dec; (129):258-78. PMID: 343963.
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    139. Orkin RW, Jackson G, Toole BP. Hyaluronidase activity in cultured chick embryo skin fibroblasts. Biochem Biophys Res Commun. 1977 Jul 11; 77(1):132-8. PMID: 19016.
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    140. Toole BP, Okayama M, Orkin RW, Yoshimura M, Muto M, Kaji A. Developmental roles of hyaluronate and chondroitin sulfate proteoglycans. Soc Gen Physiol Ser. 1977; 32:139-54. PMID: 333591.
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    141. Linsenmayer TF, Toole BP. Biosynthesis of different collagens and glycosaminoglycans during limb development. Birth Defects Orig Artic Ser. 1977; 13(1):19-35. PMID: 322747.
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    142. Polansky JR, Toole BP. Hyaluronidase activity during thyroxine-induced tadpole metamorphosis. Dev Biol. 1976 Oct 01; 53(1):30-5. PMID: 1086262.
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    143. Toole BP. Binding and precipitation of soluble collagens by chick embryo cartilage proteoglycan. J Biol Chem. 1976 Feb 10; 251(3):895-7. PMID: 129475.
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    144. Smith GN, Toole BP, Gross J. Hyaluronidase activity and glycosaminoglycan synthesis in the amputated newt limb: comparison of denervated, nonregenerating limbs with regenerates. Dev Biol. 1975 Apr; 43(2):221-32. PMID: 123872.
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    145. Trelstad RL, Hayashi K, Toole BP. Epithelial collagens and glycosaminoglycans in the embryonic cornea. Macromolecular order and morphogenesis in the basement membrane. J Cell Biol. 1974 Sep; 62(3):815-30. PMID: 4136721.
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    146. Toole BP, Schuetz AW. Evidence for metabolism of 1-methyladenine during induction of starfish oocyte maturation in vitro. Dev Biol. 1974 Jul; 39(1):177-82. PMID: 4857976.
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    147. Polansky JR, Toole BP, Gross J. Brain hyaluronidase: changes in activity during chick development. Science. 1974 Mar 01; 183(4127):862-4. PMID: 4810844.
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    148. Toole B, Schuetz AW, Boylan E. Uptake and cellular localization of 3H-1-methyladenine and 3H-adenine in the starfish gonad and oocytes. Gen Comp Endocrinol. 1974 Feb; 22(2):199-208. PMID: 4815161.
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    149. Toole BP. Extracellular events in limb development. Birth Defects Orig Artic Ser. 1974; 10(9):187-91. PMID: 4417539.
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    150. Linsenmayer TF, Toole BP, Trelstad RL. Temporal and spatial transitions in collagen types during embryonic chick limb development. Dev Biol. 1973 Dec; 35(2):232-9. PMID: 4788220.
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    151. Linsenmayer TF, Trelstad RL, Toole BP, Gross J. The collagen of osteogenic cartilage in the embryonic chick. Biochem Biophys Res Commun. 1973 Jun 08; 52(3):870-6. PMID: 4710569.
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    152. Toole BP. Hyaluronate inhibition of chondrogenesis: antagonism of thyroxine, growth hormone, and calcitonin. Science. 1973 Apr 20; 180(4083):302-3. PMID: 4349508.
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    153. Harper E, Toole BP. Collagenase and hyaluronidase stimulation by dibutyryl adenosine cyclic 3':5'-monophosphate. J Biol Chem. 1973 Apr 10; 248(7):2625-6. PMID: 4349043.
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    154. Toole BP. Hyaluronate turnover during chondrogenesis in the developing chick limb and axial skeleton. Dev Biol. 1972 Nov; 29(3):321-9. PMID: 4652271.
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    155. Trelstad RL, Kang AH, Toole BP, Gross J. Collagen heterogeneity. High resolution separation of native ( 1(I) 2 2 and ( 1(II) 3 and their component chains. J Biol Chem. 1972 Oct 25; 247(20):6469-73. PMID: 5076766.
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    156. Toole BP, Jackson G, Gross J. Hyaluronate in morphogenesis: inhibition of chondrogenesis in vitro. Proc Natl Acad Sci U S A. 1972 Jun; 69(6):1384-6. PMID: 4504347.
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    157. Toole BP, Kang AH, Trelstad RL, Gross J. Collagen heterogeneity within different growth regions of long bones of rachitic and non-rachitic chicks. Biochem J. 1972 May; 127(4):715-20. PMID: 4651137.
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    158. Toole BP, Trelstad RL. Hyaluronate production and removal during corneal development in the chick. Dev Biol. 1971 Sep; 26(1):28-35. PMID: 5111769.
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    159. Toole BP, Gross J. The extracellular matrix of the regenerating newt limb: synthesis and removal of hyaluronate prior to differentiation. Dev Biol. 1971 May; 25(1):57-77. PMID: 5557969.
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    160. Gross J, Trelstad R, Kang A, Toole B, Igarashi S. Heterogeneity of collagen molecules. Isr J Med Sci. 1971 Mar; 7(3):453-4. PMID: 5567512.
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    161. Toole BP. Solubility of collagen fibrils formed in vitro in the presence of sulphated acid mucopolysaccharide-protein. Nature. 1969 May 31; 222(5196):872-3. PMID: 4238970.
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    162. Toole BP, Lowther DA. Dermatan sulfate-protein: isolation from and interaction with collagen. Arch Biochem Biophys. 1968 Dec; 128(3):567-78. PMID: 4236454.
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    163. Toole BP, Lowther DA. The effect of chondroitin sulphate-protein on the formation of collagen fibrils in vitro. Biochem J. 1968 Oct; 109(5):857-66. PMID: 5696867.
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    164. Toole BP, Lowther DA. Precipitation of collagen fibrils in vitro by protein polysaccharides. Biochem Biophys Res Commun. 1967 Nov 30; 29(4):515-20. PMID: 16496528.
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    165. Toole BP, Lowther DA. The organisation of hexosamine-containing compounds in bovine skin. Biochim Biophys Acta. 1966 Jun 29; 121(2):315-25. PMID: 4225462.
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    166. Toole BP, Lowther DA. The isolation of a dermatan sulphate-protein complex from bovine heart valves. Biochim Biophys Acta. 1965 Nov 01; 101(3):364-6. PMID: 4222033.
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