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Institution

Adviye Ergul

Title
InstitutionMedical University of South Carolina
DepartmentPathology and Laboratory Medicine
AddressP.O. Box MSC 908
STB 401
Thurmond Gazes - 30 Courtenay Drive
Phone843-876-5958
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Fouda AY, Fagan SC, Ergul A. Brain Vasculature and Cognition. Arterioscler Thromb Vasc Biol. 2019 Apr; 39(4):593-602. PMID: 30816798.
      View in: PubMed
    2. Eldahshan W, Ishrat T, Pillai B, Sayed MA, Alwhaibi A, Fouda AY, Ergul A, Fagan SC. Angiotensin II type 2 receptor stimulation with compound 21 improves neurological function after stroke in female rats: a pilot study. Am J Physiol Heart Circ Physiol. 2019 May 01; 316(5):H1192-H1201. PMID: 30822121.
      View in: PubMed
    3. Ward R, Valenzuela JP, Li W, Dong G, Fagan SC, Ergul A. Poststroke cognitive impairment and hippocampal neurovascular remodeling: the impact of diabetes and sex. Am J Physiol Heart Circ Physiol. 2018 Nov 01; 315(5):H1402-H1413. PMID: 30118341.
      View in: PubMed
    4. Abdul Y, Abdelsaid M, Li W, Webb RC, Sullivan JC, Dong G, Ergul A. Inhibition of Toll-Like Receptor-4 (TLR-4) Improves Neurobehavioral Outcomes After Acute Ischemic Stroke in Diabetic Rats: Possible Role of Vascular Endothelial TLR-4. Mol Neurobiol. 2019 Mar; 56(3):1607-1617. PMID: 29909454.
      View in: PubMed
    5. Lima VV, Giachini FR, Matsumoto T, Li W, Bressan AF, Chawla D, Webb RC, Ergul A, Tostes RC. High-fat diet increases O-GlcNAc levels in cerebral arteries: a link to vascular dysfunction associated with hyperlipidaemia/obesity? Clin Sci (Lond). 2016 06 01; 130(11):871-80. PMID: 26929437.
      View in: PubMed
    6. Thompson JA, Hardigan TA, Carrillo-Sepulveda MA, Mintz JD, Ergul A, Diamond MP, Webb RC. The contribution of Toll-like receptors to placental inflammation in diet-induced maternal obesity. Placenta. 2015 Oct; 36(10):1204-6. PMID: 26282853.
      View in: PubMed
    7. Goulopoulou S, Hannan JL, Matsumoto T, Ogbi S, Ergul A, Webb RC. Reduced vascular responses to soluble guanylyl cyclase but increased sensitivity to sildenafil in female rats with type 2 diabetes. Am J Physiol Heart Circ Physiol. 2015 Jul 15; 309(2):H297-304. PMID: 25957216.
      View in: PubMed
    8. Coucha M, Li W, Hafez S, Abdelsaid M, Johnson MH, Fagan SC, Ergul A. SOD1 overexpression prevents acute hyperglycemia-induced cerebral myogenic dysfunction: relevance to contralateral hemisphere and stroke outcomes. Am J Physiol Heart Circ Physiol. 2015 Mar 01; 308(5):H456-66. PMID: 25552308.
      View in: PubMed
    9. Coucha M, Li W, Johnson MH, Fagan SC, Ergul A. Reply to "Letter to the editor: 'Targeting cerebrovascular myogenic dysfunction in stroke'". Am J Physiol Heart Circ Physiol. 2014 May 15; 306(10):H1483. PMID: 24833734.
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    10. Abdelsaid M, Kaczmarek J, Coucha M, Ergul A. Dual endothelin receptor antagonism with bosentan reverses established vascular remodeling and dysfunctional angiogenesis in diabetic rats: relevance to glycemic control. Life Sci. 2014 Nov 24; 118(2):268-73. PMID: 24447630.
      View in: PubMed
    11. Abdelsaid M, Ma H, Coucha M, Ergul A. Late dual endothelin receptor blockade with bosentan restores impaired cerebrovascular function in diabetes. Life Sci. 2014 Nov 24; 118(2):263-7. PMID: 24434796.
      View in: PubMed
    12. Goulopoulou S, Hannan JL, Matsumoto T, Ergul A, Webb RC. Augmented dilation to nitric oxide in uterine arteries from rats with type 2 diabetes: implications for vascular adaptations to pregnancy. Am J Physiol Heart Circ Physiol. 2014 Feb 15; 306(4):H610-8. PMID: 24337459.
      View in: PubMed
    13. Coucha M, Li W, Johnson MH, Fagan SC, Ergul A. Protein nitration impairs the myogenic tone of rat middle cerebral arteries in both ischemic and nonischemic hemispheres after ischemic stroke. Am J Physiol Heart Circ Physiol. 2013 Dec; 305(12):H1726-35. PMID: 24097431.
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    14. Lobato NS, Filgueira FP, Prakash R, Giachini FR, Ergul A, Carvalho MH, Webb RC, Tostes RC, Fortes ZB. Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese Zucker rats. PLoS One. 2013; 8(5):e63449. PMID: 23667622.
      View in: PubMed
    15. Kelly-Cobbs AI, Prakash R, Li W, Pillai B, Hafez S, Coucha M, Johnson MH, Ogbi SN, Fagan SC, Ergul A. Targets of vascular protection in acute ischemic stroke differ in type 2 diabetes. Am J Physiol Heart Circ Physiol. 2013 Mar 15; 304(6):H806-15. PMID: 23335797.
      View in: PubMed
    16. Coucha M, Li W, Ergul A. The effect of endothelin receptor A antagonism on basilar artery endothelium-dependent relaxation after ischemic stroke. Life Sci. 2012 Oct 15; 91(13-14):676-80. PMID: 22365958.
      View in: PubMed
    17. Allahdadi KJ, Hannan JL, Ergul A, Tostes RC, Webb RC. Internal pudendal artery from type 2 diabetic female rats demonstrate elevated endothelin-1-mediated constriction. J Sex Med. 2011 Sep; 8(9):2472-83. PMID: 21718448.
      View in: PubMed
    18. Li W, Sachidanandam K, Ergul A. Comparison of selective versus dual endothelin receptor antagonism on cerebrovascular dysfunction in diabetes. Neurol Res. 2011 Mar; 33(2):185-91. PMID: 21801593.
      View in: PubMed
    19. Kelly-Cobbs AI, Harris AK, Elgebaly MM, Li W, Sachidanandam K, Portik-Dobos V, Johnson M, Ergul A. Endothelial endothelin B receptor-mediated prevention of cerebrovascular remodeling is attenuated in diabetes because of up-regulation of smooth muscle endothelin receptors. J Pharmacol Exp Ther. 2011 Apr; 337(1):9-15. PMID: 21205912.
      View in: PubMed
    20. Carneiro FS, Giachini FR, Carneiro ZN, Lima VV, Ergul A, Webb RC, Tostes RC. Erectile dysfunction in young non-obese type II diabetic Goto-Kakizaki rats is associated with decreased eNOS phosphorylation at Ser1177. J Sex Med. 2010 Nov; 7(11):3620-34. PMID: 20807325.
      View in: PubMed
    21. Lima VV, Giachini FR, Carneiro FS, Carneiro ZN, Saleh MA, Pollock DM, Fortes ZB, Carvalho MH, Ergul A, Webb RC, Tostes RC. O-GlcNAcylation contributes to augmented vascular reactivity induced by endothelin 1. Hypertension. 2010 Jan; 55(1):180-8. PMID: 19948983.
      View in: PubMed
    22. Ergul A, Li W, Elgebaly MM, Bruno A, Fagan SC. Hyperglycemia, diabetes and stroke: focus on the cerebrovasculature. Vascul Pharmacol. 2009 Jul; 51(1):44-9. PMID: 19258053.
      View in: PubMed
    23. Sachidanandam K, Hutchinson JR, Elgebaly MM, Mezzetti EM, Dorrance AM, Motamed K, Ergul A. Glycemic control prevents microvascular remodeling and increased tone in type 2 diabetes: link to endothelin-1. Am J Physiol Regul Integr Comp Physiol. 2009 Apr; 296(4):R952-9. PMID: 19176890.
      View in: PubMed
    24. Giachini FR, Zemse SM, Carneiro FS, Lima VV, Carneiro ZN, Callera GE, Ergul A, Webb RC, Tostes RC. Interleukin-10 attenuates vascular responses to endothelin-1 via effects on ERK1/2-dependent pathway. Am J Physiol Heart Circ Physiol. 2009 Feb; 296(2):H489-96. PMID: 19074677.
      View in: PubMed
    25. Sachidanandam K, Hutchinson JR, Elgebaly MM, Mezzetti EM, Wang MH, Ergul A. Differential effects of diet-induced dyslipidemia and hyperglycemia on mesenteric resistance artery structure and function in type 2 diabetes. J Pharmacol Exp Ther. 2009 Jan; 328(1):123-30. PMID: 18941121.
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    26. Carneiro FS, Nunes KP, Giachini FR, Lima VV, Carneiro ZN, Nogueira EF, Leite R, Ergul A, Rainey WE, Clinton Webb R, Tostes RC. Activation of the ET-1/ETA pathway contributes to erectile dysfunction associated with mineralocorticoid hypertension. J Sex Med. 2008 Dec; 5(12):2793-807. PMID: 18823320.
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    27. Carneiro FS, Giachini FR, Lima VV, Carneiro ZN, Nunes KP, Ergul A, Leite R, Tostes RC, Webb RC. DOCA-salt treatment enhances responses to endothelin-1 in murine corpus cavernosum. Can J Physiol Pharmacol. 2008 Jun; 86(6):320-8. PMID: 18516094.
      View in: PubMed
    28. Elgebaly MM, Kelly A, Harris AK, Elewa H, Portik-Dobos V, Ketsawatsomkron P, Marrero M, Ergul A. Impaired insulin-mediated vasorelaxation in a nonobese model of type 2 diabetes: role of endothelin-1. Can J Physiol Pharmacol. 2008 Jun; 86(6):358-64. PMID: 18516099.
      View in: PubMed
    29. Sachidanandam K, Elgebaly MM, Harris AK, Hutchinson JR, Mezzetti EM, Portik-Dobos V, Ergul A. Effect of chronic and selective endothelin receptor antagonism on microvascular function in type 2 diabetes. Am J Physiol Heart Circ Physiol. 2008 Jun; 294(6):H2743-9. PMID: 18424628.
      View in: PubMed
    30. Harris AK, Elgebaly MM, Li W, Sachidanandam K, Ergul A. Effect of chronic endothelin receptor antagonism on cerebrovascular function in type 2 diabetes. Am J Physiol Regul Integr Comp Physiol. 2008 Apr; 294(4):R1213-9. PMID: 18287215.
      View in: PubMed
    31. Sachidanandam K, Portik-Dobos V, Harris AK, Hutchinson JR, Muller E, Johnson MH, Ergul A. Evidence for vasculoprotective effects of ETB receptors in resistance artery remodeling in diabetes. Diabetes. 2007 Nov; 56(11):2753-8. PMID: 17670915.
      View in: PubMed
    32. Elgebaly MM, Portik-Dobos V, Sachidanandam K, Rychly D, Malcom D, Johnson MH, Ergul A. Differential effects of ET(A) and ET(B) receptor antagonism on oxidative stress in type 2 diabetes. Vascul Pharmacol. 2007 Aug-Sep; 47(2-3):125-30. PMID: 17597010.
      View in: PubMed
    33. Jafri F, Ergul A. Phosphorylation of endothelin converting enzyme-1 isoforms: relevance to subcellular localization. Exp Biol Med (Maywood). 2006 Jun; 231(6):713-7. PMID: 16740986.
      View in: PubMed
    34. Sachidanandam K, Harris A, Hutchinson J, Ergul A. Microvascular versus macrovascular dysfunction in type 2 diabetes: differences in contractile responses to endothelin-1. Exp Biol Med (Maywood). 2006 Jun; 231(6):1016-21. PMID: 16741041.
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    35. Song W, Ergul A. Type-2 diabetes-induced changes in vascular extracellular matrix gene expression: relation to vessel size. Cardiovasc Diabetol. 2006 Feb 17; 5:3. PMID: 16503991.
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    36. Portik-Dobos V, Harris AK, Song W, Hutchinson J, Johnson MH, Imig JD, Pollock DM, Ergul A. Endothelin antagonism prevents early EGFR transactivation but not increased matrix metalloproteinase activity in diabetes. Am J Physiol Regul Integr Comp Physiol. 2006 Feb; 290(2):R435-41. PMID: 16239374.
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    37. Harris AK, Hutchinson JR, Sachidanandam K, Johnson MH, Dorrance AM, Stepp DW, Fagan SC, Ergul A. Type 2 diabetes causes remodeling of cerebrovasculature via differential regulation of matrix metalloproteinases and collagen synthesis: role of endothelin-1. Diabetes. 2005 Sep; 54(9):2638-44. PMID: 16123352.
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    38. Ergul A, Johansen JS, Strømhaug C, Harris AK, Hutchinson J, Tawfik A, Rahimi A, Rhim E, Wells B, Caldwell RW, Anstadt MP. Vascular dysfunction of venous bypass conduits is mediated by reactive oxygen species in diabetes: role of endothelin-1. J Pharmacol Exp Ther. 2005 Apr; 313(1):70-7. PMID: 15608082.
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    39. Ergul A, Portik-Dobos V, Hutchinson J, Franco J, Anstadt MP. Downregulation of vascular matrix metalloproteinase inducer and activator proteins in hypertensive patients. Am J Hypertens. 2004 Sep; 17(9):775-82. PMID: 15363819.
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    40. Ergul S, Brunson CY, Hutchinson J, Tawfik A, Kutlar A, Webb RC, Ergul A. Vasoactive factors in sickle cell disease: in vitro evidence for endothelin-1-mediated vasoconstriction. Am J Hematol. 2004 Jul; 76(3):245-51. PMID: 15224360.
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    41. Anstadt MP, Franga DL, Portik-Dobos V, Pennathur A, Bannan M, Mawulawde K, Ergul A. Native matrix metalloproteinase characteristics may influence early stenosis of venous versus arterial coronary artery bypass grafting conduits. Chest. 2004 May; 125(5):1853-8. PMID: 15136400.
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    42. Mitchell BM, Dorrance AM, Ergul A, Webb RC. Sepiapterin decreases vasorelaxation in nitric oxide synthase inhibition-induced hypertension. J Cardiovasc Pharmacol. 2004 Jan; 43(1):93-8. PMID: 14668573.
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    43. Mehta SH, Webb RC, Ergul A, Tawfik A, Dorrance AM, Tawak A. Neuroprotection by tempol in a model of iron-induced oxidative stress in acute ischemic stroke. Am J Physiol Regul Integr Comp Physiol. 2004 Feb; 286(2):R283-8. PMID: 14592931.
      View in: PubMed
    44. Jafri F, Ergul A. Nuclear localization of endothelin-converting enzyme-1: subisoform specificity. Arterioscler Thromb Vasc Biol. 2003 Dec; 23(12):2192-6. PMID: 14551152.
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    45. Ergul A, Portik-Dobos V, Giulumian AD, Molero MM, Fuchs LC. Stress upregulates arterial matrix metalloproteinase expression and activity via endothelin A receptor activation. Am J Physiol Heart Circ Physiol. 2003 Nov; 285(5):H2225-32. PMID: 12842810.
      View in: PubMed
    46. Portik-Dobos V, Anstadt MP, Hutchinson J, Bannan M, Ergul A. Evidence for a matrix metalloproteinase induction/activation system in arterial vasculature and decreased synthesis and activity in diabetes. Diabetes. 2002 Oct; 51(10):3063-8. PMID: 12351448.
      View in: PubMed
    47. Grubbs AL, Anstadt MP, Ergul A. Saphenous vein endothelin system expression and activity in African American patients. Arterioscler Thromb Vasc Biol. 2002 Jul 01; 22(7):1122-7. PMID: 12117726.
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    48. Anstadt MP, Hutchinson J, Portik-Dobos V, Jafri F, Bannan M, Mawulawde K, Ergul A. Vascular endothelin converting enzyme-1 expression and activity is upregulated in clinical diabetes. Ethn Dis. 2002; 12(4):S3-5-9. PMID: 12477147.
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    49. Brothers TE, Grubbs AL, Zhang Y, Ergul A. Selective downregulation of endothelin-B receptors in diabetic African-American patients. Ethn Dis. 2002; 12(1):S1-46-50. PMID: 11913620.
      View in: PubMed
    50. Ergul A. Endothelin-1 and endothelin receptor antagonists as potential cardiovascular therapeutic agents. Pharmacotherapy. 2002 Jan; 22(1):54-65. PMID: 11794430.
      View in: PubMed
    51. Mondy JS, Anstadt MP, Franga DL, Portik-Dobos V, Hutchinson J, Ergul A. Decreased vascular matrix metalloproteinase abundance in diabetic patients with symptomatic macroangiopathy. Ethn Dis. 2002; 12(4):S3-18-22. PMID: 12477149.
      View in: PubMed
    52. Ergul A, Joffs C, Walker AC, Spinale FG. Potential role of endothelin receptor antagonists in the setting of cardiopulmonary bypass: relevance to myocardial performance. Heart Fail Rev. 2001 Dec; 6(4):287-94. PMID: 11447303.
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    53. Walker CA, Ergul A, Grubbs A, Zile MR, Zellner JL, Crumbley AJ, Spinale FG. beta-Adrenergic and endothelin receptor interaction in dilated human cardiomyopathic myocardium. J Card Fail. 2001 Jun; 7(2):129-37. PMID: 11420764.
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    54. Grubbs AL, Ergul A. A review of endothelin and hypertension in African-American individuals. Ethn Dis. 2001; 11(4):741-8. PMID: 11763297.
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    55. Ergul A, Grubbs AL, Zhang Y, Spinale FG. Selective upregulation of endothelin converting enzyme-1a in the human failing heart. J Card Fail. 2000 Dec; 6(4):314-20. PMID: 11145756.
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    56. Walker CA, Baicu SC, Goldberg AT, Widener CE, Fary DJ, Almany DK, Ergul A, Crawford FA, Spinale FG. Temporal endothelin dynamics of the myocardial interstitium and systemic circulation in cardiopulmonary bypass. J Thorac Cardiovasc Surg. 2000 Nov; 120(5):864-71. PMID: 11044311.
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    57. Ergul A. Hypertension in black patients: an emerging role of the endothelin system in salt-sensitive hypertension. Hypertension. 2000 Jul; 36(1):62-7. PMID: 10904013.
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    58. Ergul A, Walker CA, Goldberg A, Baicu SC, Hendrick JW, King MK, Spinale FG. ET-1 in the myocardial interstitium: relation to myocyte ECE activity and expression. Am J Physiol Heart Circ Physiol. 2000 Jun; 278(6):H2050-6. PMID: 10843904.
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